J. Sarker, Md. Rahmat Ali, M. A. Khan, M. Rahman, A. S. Hossain, A. Alam
{"title":"The Plant Aerva sanguinolenta: A Review on Traditional uses, Phytoconstituents and Pharmacological Activities","authors":"J. Sarker, Md. Rahmat Ali, M. A. Khan, M. Rahman, A. S. Hossain, A. Alam","doi":"10.5530/phrev.2019.2.9","DOIUrl":"https://doi.org/10.5530/phrev.2019.2.9","url":null,"abstract":"","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74747197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Narrative and Meta‑Analytic Study of in vivo Efficiency of the Bioactive Compounds of Propolis in Tooth Decay","authors":"Y. Kim, Y. Yong, Muhammad Shahzad Aslam","doi":"10.5530/PHREV.2019.2.1","DOIUrl":"https://doi.org/10.5530/PHREV.2019.2.1","url":null,"abstract":"","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78788107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danilo Maciel Carneiro, T. Jardim, Y. Araújo, A. Arantes, A. Sousa, W. Barroso, A. Sousa, L. C. Cunha, Hérica Núbia Cardoso Cirilo, M. Bara, P. Jardim
1Hypertension League, School of Medicine, Federal University of Goiás (UFG). Goiânia Goiás, BRAZIL. 2Reference Center in Integrative and Complementary Medicine of the State Health Department of Goiás, Goiânia – Goiás, BRAZIL. 3NEPET-UFG – Toxicopharmacological Studies and Research Group (School of Pharmacy-UFG). Goiânia – Goiás, BRAZIL. 4School of Medicine of UFG. FM/HC/UFG Hypertension League. Goiânia – Goiás, BRAZIL.
{"title":"Equisetum arvense: New Evidences Supports Medical use in Daily Clinic","authors":"Danilo Maciel Carneiro, T. Jardim, Y. Araújo, A. Arantes, A. Sousa, W. Barroso, A. Sousa, L. C. Cunha, Hérica Núbia Cardoso Cirilo, M. Bara, P. Jardim","doi":"10.5530/PHREV.2019.2.4","DOIUrl":"https://doi.org/10.5530/PHREV.2019.2.4","url":null,"abstract":"1Hypertension League, School of Medicine, Federal University of Goiás (UFG). Goiânia Goiás, BRAZIL. 2Reference Center in Integrative and Complementary Medicine of the State Health Department of Goiás, Goiânia – Goiás, BRAZIL. 3NEPET-UFG – Toxicopharmacological Studies and Research Group (School of Pharmacy-UFG). Goiânia – Goiás, BRAZIL. 4School of Medicine of UFG. FM/HC/UFG Hypertension League. Goiânia – Goiás, BRAZIL.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76688132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.4103/PHREV.PHREV_26_18
A. Nurcahyanti
Cancer has become a growing health threat due to the emergence of multidrug resistance and the increasing diversity of cancer cells. The continuous investigation into the development of anticancer agents and treatments is crucial because the current treatments can cause adverse side effects and are often ineffective. Anticancer derived medicinal plants are a potential source of treatment. However, the abundance of medicinal plant species can cause several problems, like the adulteration. The author aims to demonstrate DNA Barcoding technique as a tool to perform phylogenetic positions of Mangifera and Impatiens species grown in Sumatra. The phylogenetic positions of the plants are supported by the review on the active secondary metabolites from Mangifera and Impatiens. The current study is based on unpublished work on DNA Barcoding technique, an established modern technique to identify the phylogenetic position and also adulteration in medicinal plants. The review on the active secondary metabolites including the mechanism of action as anticancer is based on pertinent papers that were retrieved using relevant keywords in PubMed and Science Direct. Work using DNA Barcoding technique confirmed that Mangifera and Impatiens from Sumatra are closely related to Momordica foetida and Impatiens balsamina from other areas, indicating that they may share the same anticancer traits with those species. The mechanism of action of Mangifera and Impatiens includes inhibition of the cell cycle, cytotoxicity activity, apoptosis and leading to cell death, and anti-angiogenesis activity. Further research on both species is needed to identify their relevant chemical components to potentially develop anticancer drugs, either as a single compound or as a drug combination with minimal side effects and also to determine possible adverse reactions.
{"title":"Mangifera and Impatiens from Sumatra: Phylogenetic positions and their modes of action as anticancer agents","authors":"A. Nurcahyanti","doi":"10.4103/PHREV.PHREV_26_18","DOIUrl":"https://doi.org/10.4103/PHREV.PHREV_26_18","url":null,"abstract":"Cancer has become a growing health threat due to the emergence of multidrug resistance and the increasing diversity of cancer cells. The continuous investigation into the development of anticancer agents and treatments is crucial because the current treatments can cause adverse side effects and are often ineffective. Anticancer derived medicinal plants are a potential source of treatment. However, the abundance of medicinal plant species can cause several problems, like the adulteration. The author aims to demonstrate DNA Barcoding technique as a tool to perform phylogenetic positions of Mangifera and Impatiens species grown in Sumatra. The phylogenetic positions of the plants are supported by the review on the active secondary metabolites from Mangifera and Impatiens. The current study is based on unpublished work on DNA Barcoding technique, an established modern technique to identify the phylogenetic position and also adulteration in medicinal plants. The review on the active secondary metabolites including the mechanism of action as anticancer is based on pertinent papers that were retrieved using relevant keywords in PubMed and Science Direct. Work using DNA Barcoding technique confirmed that Mangifera and Impatiens from Sumatra are closely related to Momordica foetida and Impatiens balsamina from other areas, indicating that they may share the same anticancer traits with those species. The mechanism of action of Mangifera and Impatiens includes inhibition of the cell cycle, cytotoxicity activity, apoptosis and leading to cell death, and anti-angiogenesis activity. Further research on both species is needed to identify their relevant chemical components to potentially develop anticancer drugs, either as a single compound or as a drug combination with minimal side effects and also to determine possible adverse reactions.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"28 1","pages":"16 - 23"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75513960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernanda Granja da Silva Oliveira, B. O. Veras, J. Silva, D. D. S. Barbosa, Tayane de Cássia Dias Mendes Silva, L. Amorim, C. Assis, Elisabete Regina Fernandes Ramos Ribeiro, A. G. Silva, M. Silva, J. Almeida
Cite this article: Oliveira FGS, Veras BO, Silva JMDS, Barbosa DCS, Silva TCDM, Amorim LC, et al. Medicinal Plants with Acetylcholinesterase Inhibitory Activity: Therapeutic Potential of Brazilian Plants for the Treatment of Alzheimer’s Disease. Phcog Rev 2019;13(26):45-9. ABSTRACT Alzheimer’s disease (AD) is characterized by persistent impairment of cognitive and psychomotor functions, resulting in reduced short-term memory. In current pharmacotherapy, some available acetylcholinesterase inhibitors (AChEi) have side effects, such as hepatotoxicity. Hence, it is necessary to investigate other sources to obtain compounds inhibiting AChE. In this context, the objective of this study was to review the main publications involving plants collected in Brazil tested for the inhibition of AChE, which may lead to new phytotherapeutic inhibitors. This review was carried out by searching the PubMed, Scopus, and Science Direct databases during September 2018, using several combinations of the following keywords: extract, AChE, Brazil and Alzheimer’s. Inclusion criteria were articles with plant studies collected in Brazil for the inhibition of AChE (in vivo and/or in vitro), with keywords in the title, abstract, or full text. Articles with studies of purified, synthetic, or semi-synthetic compounds were excluded. In this research, 298 articles were identified and 31 articles were selected. More than forty species of the families Fabaceae, Anacardiaceae, Annonaceae, Malvaceae, Myrtaceae, Arecaceae and Lauraceae were found, and the most cited substances were the phenolic compounds and flavonoids. Alkaloids and steroids were also found in some active plants. The relevance and importance of this work lies in the review of new potential herbal drugs for the treatment of AD, and this survey could collaborate for the development of new medicinal alternatives for this and other neurodegenerative problems related to cerebral availability of acetylcholine.
{"title":"Medicinal Plants with Acetylcholinesterase Inhibitory Activity: Therapeutic Potential of Brazilian Plants for the Treatment of Alzheimer's Disease","authors":"Fernanda Granja da Silva Oliveira, B. O. Veras, J. Silva, D. D. S. Barbosa, Tayane de Cássia Dias Mendes Silva, L. Amorim, C. Assis, Elisabete Regina Fernandes Ramos Ribeiro, A. G. Silva, M. Silva, J. Almeida","doi":"10.5530/phrev.2019.2.3","DOIUrl":"https://doi.org/10.5530/phrev.2019.2.3","url":null,"abstract":"Cite this article: Oliveira FGS, Veras BO, Silva JMDS, Barbosa DCS, Silva TCDM, Amorim LC, et al. Medicinal Plants with Acetylcholinesterase Inhibitory Activity: Therapeutic Potential of Brazilian Plants for the Treatment of Alzheimer’s Disease. Phcog Rev 2019;13(26):45-9. ABSTRACT Alzheimer’s disease (AD) is characterized by persistent impairment of cognitive and psychomotor functions, resulting in reduced short-term memory. In current pharmacotherapy, some available acetylcholinesterase inhibitors (AChEi) have side effects, such as hepatotoxicity. Hence, it is necessary to investigate other sources to obtain compounds inhibiting AChE. In this context, the objective of this study was to review the main publications involving plants collected in Brazil tested for the inhibition of AChE, which may lead to new phytotherapeutic inhibitors. This review was carried out by searching the PubMed, Scopus, and Science Direct databases during September 2018, using several combinations of the following keywords: extract, AChE, Brazil and Alzheimer’s. Inclusion criteria were articles with plant studies collected in Brazil for the inhibition of AChE (in vivo and/or in vitro), with keywords in the title, abstract, or full text. Articles with studies of purified, synthetic, or semi-synthetic compounds were excluded. In this research, 298 articles were identified and 31 articles were selected. More than forty species of the families Fabaceae, Anacardiaceae, Annonaceae, Malvaceae, Myrtaceae, Arecaceae and Lauraceae were found, and the most cited substances were the phenolic compounds and flavonoids. Alkaloids and steroids were also found in some active plants. The relevance and importance of this work lies in the review of new potential herbal drugs for the treatment of AD, and this survey could collaborate for the development of new medicinal alternatives for this and other neurodegenerative problems related to cerebral availability of acetylcholine.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85257050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ethnobotany and Pharmacognosy of Qust/ Kut (Saussurea lappa, C. B. Clarke) with Special Reference of Unani Medicine","authors":"S. Ansari","doi":"10.5530/phrev.2019.2.7","DOIUrl":"https://doi.org/10.5530/phrev.2019.2.7","url":null,"abstract":"","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87208170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vietnamese Ginseng (Panax vietnamensis Ha and Grushv.): Phylogenetic, Phytochemical, and Pharmacological Profiles","authors":"T. Nguyen, T. Phuong","doi":"10.5530/phrev.2019.2.5","DOIUrl":"https://doi.org/10.5530/phrev.2019.2.5","url":null,"abstract":"","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89566390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.4103/PHREV.PHREV_25_18
I. Ng, C. Chua
Xanthones are well known for their significant biological activities and can be found in many herbal medicines. These compounds have the ability to regulate various inflammatory activities and signaling pathways in immune cells, especially macrophages. Macrophages are innate immune cells that can either fuel or dampen an inflammatory response depending on their activation states and play an active role in the development of inflammatory diseases such as atherosclerosis, arthritis, cancer, and diabetes. Many traditional medicines used as a remedy for these diseases contain xanthones, and their bioactivities may be partially attributed to their ability in regulating macrophage responses. In this review, we discuss the in vitro and in vivo findings on the effects of xanthones on different macrophage immune functions including nitric oxide and cytokine production, migration, polarization, and phagocytosis. Their specific modes of action are highlighted whenever known. We also discuss the potential and challenges in using xanthones as a therapeutic option in various inflammatory diseases. It is hoped that this review can pave the way for future research that focuses on developing xanthones as specific macrophage-targeted therapeutics.
{"title":"The potential of xanthones as a therapeutic option in macrophage-associated inflammatory diseases","authors":"I. Ng, C. Chua","doi":"10.4103/PHREV.PHREV_25_18","DOIUrl":"https://doi.org/10.4103/PHREV.PHREV_25_18","url":null,"abstract":"Xanthones are well known for their significant biological activities and can be found in many herbal medicines. These compounds have the ability to regulate various inflammatory activities and signaling pathways in immune cells, especially macrophages. Macrophages are innate immune cells that can either fuel or dampen an inflammatory response depending on their activation states and play an active role in the development of inflammatory diseases such as atherosclerosis, arthritis, cancer, and diabetes. Many traditional medicines used as a remedy for these diseases contain xanthones, and their bioactivities may be partially attributed to their ability in regulating macrophage responses. In this review, we discuss the in vitro and in vivo findings on the effects of xanthones on different macrophage immune functions including nitric oxide and cytokine production, migration, polarization, and phagocytosis. Their specific modes of action are highlighted whenever known. We also discuss the potential and challenges in using xanthones as a therapeutic option in various inflammatory diseases. It is hoped that this review can pave the way for future research that focuses on developing xanthones as specific macrophage-targeted therapeutics.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"70 1","pages":"28 - 33"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81117076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.4103/PHREV.PHREV_29_18
Yik-Ling Chew
Atopic dermatitis (AD) is a chronic, inflammatory skin disease that is characterized by intense pruritus and eczematous lesions. It is an increasingly pruritic inflammatory skin disorder which can affect both children and adults. Natural products offer great hope in the identification of bioactive lead compounds and their development into topical cream or ointment in managing skin diseases which are associated with inflammatory response. One of the most popular natural products which have been vastly used in managing AD is virgin coconut oil (VCO). VCO is extracted from the fresh and mature kernel of the coconut (Cocos nucifera L.) through wet and dry methods, without altering the valuable phytochemicals and physiochemical properties of the oil. It possesses numerous health benefits from the retained physiochemical properties from its triglycerides and medium chain fatty acids. The use of VCO in the management of AD is one of the topical therapies which have been proven to have good therapeutic effects and it is safe for topical applications. Studies have been proven that VCO exhibits antioxidant, anti-inflammatory, antibacterial, wound healing, and moisturizing properties which were extremely important in the management of AD.
{"title":"The beneficial properties of virgin coconut oil in management of atopic dermatitis","authors":"Yik-Ling Chew","doi":"10.4103/PHREV.PHREV_29_18","DOIUrl":"https://doi.org/10.4103/PHREV.PHREV_29_18","url":null,"abstract":"Atopic dermatitis (AD) is a chronic, inflammatory skin disease that is characterized by intense pruritus and eczematous lesions. It is an increasingly pruritic inflammatory skin disorder which can affect both children and adults. Natural products offer great hope in the identification of bioactive lead compounds and their development into topical cream or ointment in managing skin diseases which are associated with inflammatory response. One of the most popular natural products which have been vastly used in managing AD is virgin coconut oil (VCO). VCO is extracted from the fresh and mature kernel of the coconut (Cocos nucifera L.) through wet and dry methods, without altering the valuable phytochemicals and physiochemical properties of the oil. It possesses numerous health benefits from the retained physiochemical properties from its triglycerides and medium chain fatty acids. The use of VCO in the management of AD is one of the topical therapies which have been proven to have good therapeutic effects and it is safe for topical applications. Studies have been proven that VCO exhibits antioxidant, anti-inflammatory, antibacterial, wound healing, and moisturizing properties which were extremely important in the management of AD.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"10 1","pages":"24 - 27"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88211613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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