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Effects of Exosome-Containing Skin Booster and Microneedling Treatment on Facial Aging: A Retrospective Analysis of 40 Cases. 含外泌体促肤剂联合微针治疗面部衰老40例回顾性分析。
Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1097/PSN.0000000000000631
Byungki Cho, Kyung-Tae Bae, Jovian Wan, Kyu-Ho Yi

Skin aging is caused by extrinsic and intrinsic factors and can lead to various aesthetic concerns and psychosocial stress. Exosome-based treatments have recently gained attention in the field of skin rejuvenation. This study aimed to retrospectively analyze the clinical efficacy of an exosome (CUREDOC EXOSOME REPAIR Advanced Solution Skin Booster, CUREDOC, Sejong, Korea) combined with microneedling treatment. We analyzed the medical records of 40 patients who received exosome skin booster (50 mcg/mL) and microneedling combination therapy at a single medical institution from January to March 2024. Physicians performed the treatment on each patient every 2 weeks for a total of 4 sessions. The physicians followed each patient for 8 weeks after the final treatment. The physicians evaluated each patient by taking clinical photographs, having each patient complete a satisfaction survey, assessing each patient using the Global Aesthetic Improvement Scale (GAIS), and documenting adverse events. The patient group had a mean age of 41.2 ± 6.3 years. The results of the study showed a high patient acceptance rate, with an overall satisfaction of 87.5%, an 82% intention to undergo repeat treatment, and an 85% willingness to recommend the treatment. According to the GAIS assessments, 85% of patients scored "improved" or greater. Adverse events were transient and mild, and there were no serious adverse reactions reported. Based on the results of this study, the combination of exosome skin booster and microneedling treatment can be considered a safe and effective option for improving facial aging.

皮肤老化是由外在和内在因素引起的,并可能导致各种审美问题和社会心理压力。近年来,基于外泌体的治疗方法在皮肤再生领域受到了广泛关注。本研究旨在回顾性分析外泌体(CUREDOC exosome REPAIR Advanced Solution Skin Booster, CUREDOC, Sejong, Korea)联合微针治疗的临床疗效。我们分析了2024年1月至3月在同一医疗机构接受外泌体皮肤增强剂(50 mcg/mL)和微针联合治疗的40例患者的病历。医生每两周对每位患者进行一次治疗,共进行4次治疗。医生在最终治疗后随访每位患者8周。医生通过拍摄临床照片,让每位患者完成满意度调查,使用全球审美改善量表(GAIS)评估每位患者,并记录不良事件,对每位患者进行评估。患者组平均年龄41.2±6.3岁。研究结果显示,患者接受率高,总体满意度为87.5%,82%的患者愿意重复治疗,85%的患者愿意推荐治疗。根据GAIS评估,85%的患者得分“改善”或更高。不良事件是短暂的和轻微的,没有严重的不良反应报道。基于本研究的结果,外泌体皮肤增强剂和微针治疗相结合可以被认为是改善面部衰老的安全有效的选择。
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引用次数: 0
Strategies to Enhance Flap Survival and Prevent Hematoma in Osmidrosis Surgery. 提高瓣存活及预防血肿的策略。
Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1097/PSN.0000000000000670
Wen-Tsao Ho
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引用次数: 0
Pressure Injuries and the Plastic and Aesthetic Nurse. 压伤与整形美容护理。
Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1097/PSN.0000000000000681
Kathleen Soso
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引用次数: 0
Investigation of the Relationship Between Health Literacy and Surgical Acceptance in Aesthetic Surgery Patients. 美容手术患者健康素养与手术接受度关系的调查。
Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1097/PSN.0000000000000638
İbrahim Kiyat, Nuray Akyüz

In this cross-sectional study, we evaluated the relationship between health literacy and acceptance of cosmetic surgery using the Turkish Health Literacy Scale-32 and the Acceptance of Cosmetic Surgery Scale. The mean age of the 379 patients included in the study was 31.19 ± 7.02 years. A total of 61.7% (n = 234) of the participants had a history of cosmetic surgery. The most common aesthetic surgery was performed on the face, and the most preferred type of surgical intervention was rhinoplasty. Patients stated that they primarily obtained information about plastic surgery from social media and the internet. We found a strong statistically significant positive correlation between the two scales (r = 0.757; p < .001). We found statistically significantly different scale scores based on the patients' education (p < .001) and income levels (p < .05). Patients with a history of plastic surgery had statistically significant higher acceptance levels (p = .003). There is a need for education and counseling services to increase the health literacy of plastic surgery patients and support them in making informed decisions.

在这项横断面研究中,我们使用土耳其健康素养量表-32和接受整容手术量表评估了健康素养与接受整容手术之间的关系。纳入研究的379例患者平均年龄为31.19±7.02岁。共有61.7% (n = 234)的参与者有整容手术史。最常见的美容手术是在面部进行的,最受欢迎的手术干预类型是鼻整形术。患者表示,他们主要从社交媒体和互联网上获取有关整形手术的信息。我们发现两个量表之间有很强的统计学显著正相关(r = 0.757; p < 0.001)。我们发现患者的教育程度和收入水平在量表得分上存在显著差异(p < 0.001)。有整形手术史的患者接受度有统计学意义(p = 0.003)。有必要提供教育和咨询服务,以提高整形手术患者的健康素养,并支持他们做出明智的决定。
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引用次数: 0
Past and Present. 过去和现在。
Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1097/PSN.0000000000000685
Lisa Griffin
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引用次数: 0
Shaping the Future of ISPAN. 塑造ISPAN的未来。
Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1097/PSN.0000000000000688
Rebecca Suess
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引用次数: 0
Gender-Affirming Genital Masculinization: Part 3 of the Plastic Surgeon's Perspective of Gender-Affirming Surgery. 性别确认生殖器男性化:第三部分整形外科医生的性别确认手术的观点。
Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1097/PSN.0000000000000689
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引用次数: 0
Long-Term Safety and Efficacy of Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid to Improve Skin Laxity of the Inner Upper Arms: A Single-Arm Study. 高分子量和低分子量透明质酸混合配合物改善上臂内侧皮肤松弛的长期安全性和有效性:单臂研究
Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1097/PSN.0000000000000636
Adele Sparavigna, Clara Cigni, Laura Tanzini, Roberto Lualdi, Franco Grimolizzi

In a single-center study conducted over a 12-month study period, we investigated the long-term safety and efficacy of Profilo Body® (IBSA Farmaceutici Italia Srl, Lodi, Italy) for treating upper inner arm skin laxity. The study participants included women (37-65 years) with at least initial signs of skin laxity and roughness on their upper arms. The treatment consisted of two injections of Profhilo Body® one month apart, followed by five injections two months apart, and a follow-up evaluation one month later. We assessed the study participants using the IBSA Photographic Scale for Assessment of Upper Inner Arm Skin Laxity. At the end of the study, the participants also completed a self-evaluation questionnaire related to product efficacy and tolerability. A total of 34 enrolled participants received the first three injections. A total of 32 participants received the next four injections. We found that slight ecchymosis occurred in 36 participants. The results of the study showed a significant decrease in median IBSA Photographic Scale for Assessment of Upper Inner Arm Skin Laxity scores at Month 3 compared with baseline scores (p < .0001). This decrease was maintained through Month 12. At least 50% of the participants experienced a moderate improvement in skin firmness, smoothness, brightness, hydration, and overall inner arm appearance that continued through Month 12. The participants self-evaluated tolerability of the product as "optimal." Based on the results of this study, we conclude that long-term use of Profhilo® Body is safe and effective for reducing skin laxity of the upper inner arms.

在一项为期12个月的单中心研究中,我们调查了Profilo Body®(IBSA Farmaceutici Italia Srl, Lodi, Italy)治疗上臂内侧皮肤松弛的长期安全性和有效性。研究参与者包括上臂皮肤松弛和粗糙的女性(37-65岁)。治疗包括间隔一个月两次注射Profhilo Body®,然后间隔两个月进行五次注射,并在一个月后进行随访评估。我们使用IBSA上臂内侧皮肤松弛度摄影量表对研究参与者进行评估。在研究结束时,参与者还完成了一份与产品功效和耐受性相关的自我评估问卷。共有34名参与者接受了前三次注射。共有32名参与者接受了接下来的四次注射。我们发现36名参与者出现轻微瘀斑。研究结果显示,与基线评分相比,第3个月IBSA上臂内侧皮肤松弛度摄影评分中位数显著下降(p < 0.0001)。这种下降一直持续到第12个月。至少50%的参与者经历了持续到12个月的皮肤紧致度、光滑度、亮度、水合性和整体手臂内部外观的适度改善。参与者自我评价产品的耐受性为“最佳”。根据本研究结果,我们得出结论,长期使用Profhilo®Body对于减轻上臂内侧皮肤松弛是安全有效的。
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引用次数: 0
WALANT Technique Advances Hand Surgery With Faster Recovery and Greater Efficiency. WALANT技术进步手外科手术更快的恢复和更高的效率。
Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1097/PSN.0000000000000680
Sharon Ann Van Wicklin
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引用次数: 0
Needles Versus Cannulas: Advantages, Disadvantages, and Selection Criteria for Injecting Dermal Fillers. 针与套管:注射皮肤填充物的优点、缺点和选择标准。
Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1097/PSN.0000000000000629
Gi-Woong Hong, Kyu-Ho Yi

This review explores the efficacy and safety of using needles compared with cannulas for administering dermal fillers. We assessed and compared needles and cannulas based on the accuracy of injection, amount of associated tissue damage, procedural duration, vascular complications, and injection techniques and also highlighted their respective advantages and limitations. Needles facilitate rapid, precise injections and are suitable for shallow, targeted applications; however, because of their sharp points, if not handled with exacting techniques, needles pose a higher risk for misplacement, vascular damage, and tissue trauma. Conversely, because of their blunt tips, cannulas significantly reduce the potential for perforating blood vessels and thus provide a safer alternative for use in areas with a dense vascular network such as the forehead and nasolabial folds. Although requiring a longer procedure time and the creation of an entry point, using cannulas minimizes tissue disruption and is less likely to cause severe vascular complications. This research highlights the importance of choosing the appropriate injection tool based on specific treatment areas, desired outcomes, and inherent risks. Implementing an informed approach when using needles and cannulas can enhance both patient safety and aesthetic results in facial enhancements.

这篇综述探讨了使用针头和套管进行皮肤填充物管理的有效性和安全性。我们根据注射的准确性、相关组织损伤的数量、手术时间、血管并发症和注射技术对针和套管进行了评估和比较,并强调了它们各自的优点和局限性。针头有助于快速,精确的注射,适合浅层,有针对性的应用;然而,由于针尖锋利,如果不采用严格的技术,针头会造成错位、血管损伤和组织损伤的风险更高。相反,由于其尖端较钝,插管显著减少了血管穿孔的可能性,因此为前额和鼻唇沟等血管网络密集的区域提供了更安全的选择。虽然需要较长的手术时间和创建切入点,但使用套管可以最大限度地减少组织破坏,并且不太可能引起严重的血管并发症。这项研究强调了根据具体治疗领域、预期结果和固有风险选择合适注射工具的重要性。在使用针头和套管时,实施知情的方法可以提高患者的安全性和面部增强的美观效果。
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引用次数: 0
期刊
Plastic and aesthetic nursing
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