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A Blast and Burn Hand Injury Caused by an Exploding Vaping Device in a Pediatric Patient: A Case Report. 一名儿科患者因吸食电子烟设备爆炸导致手部爆炸和烧伤:病例报告。
Pub Date : 2024-07-01 Epub Date: 2024-07-03 DOI: 10.1097/PSN.0000000000000565
Murtaza Kadhum, Abdulrahman El-Hilly, Jennifer O'Neill

In this report, we present an injury to the hand caused by an exploding vaping device. This report summarizes the burn, blast and chemical injury, and discusses best practice for treatment. This case provides a warning to healthcare professionals and the public about the potential for and the seriousness of this injury. We hope to emphasize the rising incidence of vaping among children, the injuries that may occur, and the methods for treatment.

在本报告中,我们介绍了一个因吸食电子烟装置爆炸而造成的手部伤害。本报告概述了烧伤、爆炸伤和化学伤,并讨论了最佳治疗方法。本病例为医护人员和公众提供了一个警示,让他们认识到这种伤害的潜在性和严重性。我们希望强调儿童吸食电子烟发病率的上升、可能发生的伤害以及治疗方法。
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引用次数: 0
Prevention, Diagnosis, and Management of Diplopia Secondary to Neurotoxin Injections. 继发于神经毒素注射的复视的预防、诊断和处理。
Pub Date : 2024-07-01 Epub Date: 2024-07-03 DOI: 10.1097/PSN.0000000000000579
Sharon Ann Van Wicklin
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引用次数: 0
Profhilo® Structura, Current Status and Future Perspectives: A Practical Review. Profhilo® Structura、现状和未来展望:实用综述。
Pub Date : 2024-07-01 Epub Date: 2024-07-03 DOI: 10.1097/PSN.0000000000000571
Riccardo Forte, Giovanni Salti, Antonello Tateo

Hyaluronic acid (HA)-based injectables continue to grow in popularity and are used worldwide to improve facial changes associated with aging. Profhilo® Structura (IBSA Farmaceutici Italia, Lodi, Italy) is a novel HA-based product that uses nano hybrid complex of hyaluronic acid (NAHYCO)® technology to create hybrid cooperative complexes consisting of high and low molecular weight HA. Profhilo® Structura's high concentration (45 mg of total HA) and rheological properties (ie, viscosity [resistance to flow] and elasticity [stickiness]) have been specially formulated to restore facial adipose tissue. Because of their early involvement in the facial aging process, the superficial medial and lateral-temporal cheek fat compartments are good candidates for treatment. However, recommendations and guidelines are necessary to ensure that treatment is safe and effective. Three experts were invited to IBSA Farmaceutici Italia Srl to discuss clinical rationale, optimal injection techniques, and clinical outcomes for treating the superficial medial and lateral-temporal cheek fat compartments with Profhilo® Structura. These techniques were developed using patients presenting with either initial hypotrophy of fat compartments within the preauricular area (ie, sinkers) or jowl sagging due to hypotrophy within the preauricular and zygomatic areas (ie, saggers). Targeting these areas using the optimal injection site can maximize product diffusion and minimize the risk for vascular compromise. Targeting these areas also leads to lateral tightening and lipolifting effects due to adipose tissue restoration. The experts agreed that Profhilo® Structura is currently the first and only HA-based injectable treatment that can integrate and restore the adipose tissue in these affected fat compartments.

以透明质酸(HA)为基础的注射剂越来越受欢迎,在全球范围内被用于改善与衰老相关的面部变化。Profhilo® Structura(IBSA Farmaceutici Italia,意大利洛迪)是一种以透明质酸为基础的新型产品,它采用透明质酸纳米杂化复合物(NAHYCO)® 技术,创造出由高分子量和低分子量透明质酸组成的杂化协同复合物。Profhilo® Structura 的高浓度(45 毫克总 HA)和流变特性(即粘度[流动阻力]和弹性[粘性])是专为恢复面部脂肪组织而配制的。由于脸部衰老过程的早期参与,浅内侧和外侧-颞颊脂肪区是治疗的良好候选区。不过,为了确保治疗安全有效,有必要制定相关建议和指南。三位专家应邀参加了 IBSA Farmaceutici Italia Srl 讨论 Profhilo® Structura 治疗颊浅内侧和颞外侧脂肪区的临床原理、最佳注射技术和临床效果。这些技术是根据耳前区脂肪区最初萎缩(即下陷者)或因耳前区和颧区萎缩导致下颌下垂(即下垂者)的患者情况开发的。针对这些区域采用最佳注射部位,可以最大限度地提高产品扩散效果,并将血管受损的风险降至最低。针对这些区域的注射还能通过脂肪组织的修复,达到侧向收紧和脂肪提升的效果。专家们一致认为,Profhilo® Structura 是目前第一种也是唯一一种基于 HA 的注射疗法,可以整合和恢复这些受影响脂肪区的脂肪组织。
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引用次数: 0
Study of Genetic Mutations and Their Association With the Development of Atopic Dermatitis and Other Skin Diseases. 研究基因突变及其与特应性皮炎和其他皮肤病发病的关系。
Pub Date : 2024-07-01 Epub Date: 2024-07-03 DOI: 10.1097/PSN.0000000000000564
Ilona Hartmane

The purpose of this study was to identify the heterogeneity of atopic dermatitis and to identify key genetic factors. This can lead to new approaches and personalized treatment strategies. I conducted a literature review of three scientific publication platforms (i.e., PubMed, Cochrane Library, Scopus) for records published between July 2011 and July 2023 using key words related to the genetics of atopic dermatitis. The high heritability and genetic pleiotropia of atopic dermatitis emphasize the importance of its genetic predisposition and interaction with concomitant diseases. The study also shows the role of various genes associated with immunity and inflammatory reactions, as well as the high heritability of atopic dermatitis, particularly among twins. Genetic mutations, specifically polymorphisms of genes encoding immune factors and inflammatory responses, determine an individual's predisposition to atopic dermatitis. Research findings also point to genetic aspects associated with other skin conditions such as psoriasis and vitiligo, confirming the existence of common genetic mechanisms between these diseases. Specifically, polymorphisms of the filaggrin gene have been found to be key genetic determinants of atopic dermatitis. I analyzed the genetic basis of atopic dermatitis, emphasizing the importance of genetic determinants and their interaction with the immune system and extracellular matrix. This study contributes to the understanding of the mechanisms of atopic dermatitis and opens new perspectives for individualized treatments.

这项研究的目的是确定特应性皮炎的异质性,并找出关键的遗传因素。这将有助于制定新的方法和个性化治疗策略。我在三个科学出版物平台(即 PubMed、Cochrane Library 和 Scopus)上使用特应性皮炎遗传学相关关键词对 2011 年 7 月至 2023 年 7 月期间发表的记录进行了文献综述。特应性皮炎的高遗传率和遗传多向性强调了其遗传易感性以及与伴随疾病相互作用的重要性。研究还显示了与免疫和炎症反应相关的各种基因的作用,以及特应性皮炎的高遗传性,尤其是在双胞胎中。基因突变,特别是编码免疫因子和炎症反应的基因的多态性,决定了个体易患特应性皮炎的倾向。研究结果还指出了与牛皮癣和白癜风等其他皮肤病相关的遗传因素,证实了这些疾病之间存在共同的遗传机制。具体而言,研究发现丝胶蛋白基因的多态性是特应性皮炎的关键遗传决定因素。我分析了特应性皮炎的遗传基础,强调了遗传决定因素及其与免疫系统和细胞外基质相互作用的重要性。这项研究有助于人们了解特应性皮炎的发病机制,并为个体化治疗开辟了新的前景。
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引用次数: 0
Study of Genetic Mutations and Their Association With the Development of Atopic Dermatitis and Other Skin Diseases. 研究基因突变及其与特应性皮炎和其他皮肤病发病的关系。
Pub Date : 2024-07-01 Epub Date: 2024-07-03 DOI: 10.1097/PSN.0000000000000592
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引用次数: 0
Using an Innovative Protective Sleeve to Reduce Skin Compression Complications in Axillary Osmidrosis Surgery. 使用创新型保护套减少腋窝蚕豆症手术中的皮肤压迫并发症。
Pub Date : 2024-07-01 Epub Date: 2024-07-03 DOI: 10.1097/PSN.0000000000000573
Benjamin Xi En Ho, Wen-Tsao Ho

Osmidrosis is a condition characterized by malodorous sweat production in the armpits that often necessitates surgical intervention with tie-over bandages in the axillary area. Standard tie-over bandages may cause skin compression-related complications, such as bruising and skin erosion. To address this issue, we developed a novel technique using a modified protective sleeve. We conducted an observational study involving 60 patients undergoing axillary osmidrosis surgery and divided them into groups. In the experimental group we used a novel technique that included using a modified protective sleeve secured with 4-0 silk sutures. In the control group we used standard tie-over bandages. We created the protective sleeve from the tail of a 3 mL syringe by drilling holes on both sides and securing it onto a 10 mm-wide Penrose drain. We threaded sutures through the holes and provided padding between the sutures and the skin. We assessed primary outcomes of bruising and skin breakdown at eight anchoring sites. We found that using the novel protective sleeve significantly reduced skin complications. Compared with standard bandages, the incidence of bruising was reduced by 83.33% (i.e., 16.7% vs 70%). The incidence of skin erosion was reduced by 75% (10% vs 40%). Notably, the control group exhibited delayed complications, such as hypertrophic scars.

腋臭是一种以腋窝分泌恶臭汗液为特征的疾病,通常需要在腋窝部位使用扎带进行手术干预。标准的绑扎绷带可能会引起皮肤压迫相关并发症,如瘀伤和皮肤侵蚀。为了解决这个问题,我们开发了一种使用改良保护套的新技术。我们进行了一项观察性研究,涉及 60 名接受腋窝渗出手术的患者,并将他们分成几组。在实验组中,我们采用了一种新技术,包括使用改良的保护套,并用 4-0 丝线缝合。在对照组中,我们使用了标准的绑扎绷带。我们用 3 毫升注射器的尾部制作了保护套,在两侧钻孔并将其固定在 10 毫米宽的 Penrose 引流管上。我们将缝合线穿入孔中,并在缝合线和皮肤之间提供衬垫。我们评估了八个固定部位的瘀伤和皮肤破损的主要结果。我们发现,使用新型保护套能显著减少皮肤并发症。与标准绷带相比,瘀伤发生率降低了 83.33%(即 16.7% 对 70%)。皮肤糜烂的发生率降低了 75%(10% 对 40%)。值得注意的是,对照组出现了延迟并发症,如增生性疤痕。
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引用次数: 0
Evaluating Member Needs and Planning Strategically. 评估会员需求,制定战略规划。
Pub Date : 2024-07-01 Epub Date: 2024-07-03 DOI: 10.1097/PSN.0000000000000583
Kristi Elliott
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引用次数: 0
Local Anesthetic Systemic Toxicity (LAST). 局麻药全身毒性(LAST)。
Pub Date : 2024-07-01 Epub Date: 2024-07-03 DOI: 10.1097/PSN.0000000000000582
Sharon Ann Van Wicklin
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引用次数: 0
Safe and Effective Use of Local Anesthetics. 安全有效地使用局部麻醉剂。
Pub Date : 2024-07-01 Epub Date: 2024-07-03 DOI: 10.1097/PSN.0000000000000580
Sharon Ann Van Wicklin
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引用次数: 0
Occipito-Cervico-Dorsal Flap for Neck Reconstruction After Postburn Contractures: A Case Report and Literature Review. 用于烧伤后挛缩颈部重建的枕颈背皮瓣:病例报告与文献综述
Pub Date : 2024-04-01 DOI: 10.1097/PSN.0000000000000552
Pedro Alvedro-Ruiz, Nerea Díaz-Ros, María García-García, Mar Merino-Romero, Iván Heredia-Alcalde, Belén Andresen-Lorca, Aranzazu Pérez-Plaza, María Dolores Pérez Del Caz
Because the head and neck are one of the most frequent locations of burns, it is of paramount importance that plastic surgeons and plastic surgical nurses understand the most effective surgical methods for treating neck contractures and the reconstructive technique required for each case. We introduce the case of a 42-year-old woman who presented with a severe postburn neck contracture that was reconstructed with a pedicled occipito-cervico-dorsal flap. We closed the donor-site wound primarily and completely covered the defect with good results. In addition to conventional skin grafts, dermal matrices, and microsurgical techniques, using an occipito-cervico-dorsal flap should be considered for reconstructing postburn neck contractures as it offers good aesthetic and functional outcomes, provides enough tissue and pliable skin, and results in minimal donor-site morbidity.
由于头颈部是烧伤最常见的部位之一,因此整形外科医生和整形外科护士必须了解治疗颈部挛缩最有效的手术方法以及每个病例所需的重建技术。我们介绍了一例 42 岁女性烧伤后严重颈部挛缩的病例,该病例采用带蒂枕颈背皮瓣进行了重建。我们主要封闭了供皮区伤口,并完全覆盖了缺损,取得了良好的效果。除了传统的皮肤移植、真皮基质和显微外科技术外,在重建烧伤后颈部挛缩时还应考虑使用枕颈背皮瓣,因为它具有良好的美学和功能效果,能提供足够的组织和柔韧的皮肤,并能将供体部位的发病率降至最低。
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Plastic and aesthetic nursing
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