Pub Date : 2025-01-22DOI: 10.1016/j.psycr.2025.100248
Lily Porsa DO
This paper presents a case study of a 14-year-old female admitted with first-episode psychosis and catatonic features following delta-9 tetrahydrocannabinol (THC) use. The rising prevalence of cannabis, especially among adolescents, underscores the need to distinguish between substance-induced and primary psychoses. The discussion explores the challenges in diagnosis, emphasizing predictors such as family history and trauma. Treatment strategies, including abstinence promotion, medical evaluation, and early psychosis intervention, are crucial for effective management. The case highlights the complexities of psychosis management, emphasizing a comprehensive approach for improved outcomes and prevention of future episodes.
{"title":"A case of first-episode psychosis with catatonic features in an adolescent following THC use","authors":"Lily Porsa DO","doi":"10.1016/j.psycr.2025.100248","DOIUrl":"10.1016/j.psycr.2025.100248","url":null,"abstract":"<div><div>This paper presents a case study of a 14-year-old female admitted with first-episode psychosis and catatonic features following delta-9 tetrahydrocannabinol (THC) use. The rising prevalence of cannabis, especially among adolescents, underscores the need to distinguish between substance-induced and primary psychoses. The discussion explores the challenges in diagnosis, emphasizing predictors such as family history and trauma. Treatment strategies, including abstinence promotion, medical evaluation, and early psychosis intervention, are crucial for effective management. The case highlights the complexities of psychosis management, emphasizing a comprehensive approach for improved outcomes and prevention of future episodes.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100248"},"PeriodicalIF":0.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-15DOI: 10.1016/j.psycr.2025.100247
Megan S. Barker , Neil A. Shneider , Masood Manoochehri , Edward D. Huey , Elizabeth C. Lindenberger
Although amyotrophic lateral sclerosis (ALS) is defined as a neuromuscular disease, cognitive and/or behavioral symptoms are relatively common, and a portion of ALS patients will meet criteria for behavioral variant frontotemporal dementia (bvFTD). In this report, we describe the case of a man with ALS with bvFTD (ALS-FTD) presenting with excessive emotional reactivity, including severe anger, aggression, and obsessive thoughts. We contrast this case with the decreased emotional reactivity that is usually observed in patients with bvFTD without ALS. We discuss possible explanations including that: 1) the behavioral symptoms of bvFTD and ALS-FTD are the same, but the motor dysfunction influences the clinical manifestations of the behavioral symptoms in ALS-FTD; 2) the emotional and behavioral symptoms of bvFTD and ALS-FTD are the same, but ALS-FTD patients come to clinical attention earlier in the course of their FTD than bvFTD patients without ALS; and 3) the emotional and behavioral symptoms of bvFTD and ALS-FTD could differ.
{"title":"Excessive emotional reactivity in a case of behavioral variant frontotemporal dementia with amyotrophic lateral sclerosis","authors":"Megan S. Barker , Neil A. Shneider , Masood Manoochehri , Edward D. Huey , Elizabeth C. Lindenberger","doi":"10.1016/j.psycr.2025.100247","DOIUrl":"10.1016/j.psycr.2025.100247","url":null,"abstract":"<div><div>Although amyotrophic lateral sclerosis (ALS) is defined as a neuromuscular disease, cognitive and/or behavioral symptoms are relatively common, and a portion of ALS patients will meet criteria for behavioral variant frontotemporal dementia (bvFTD). In this report, we describe the case of a man with ALS with bvFTD (ALS-FTD) presenting with excessive emotional reactivity, including severe anger, aggression, and obsessive thoughts. We contrast this case with the decreased emotional reactivity that is usually observed in patients with bvFTD without ALS. We discuss possible explanations including that: 1) the behavioral symptoms of bvFTD and ALS-FTD are the same, but the motor dysfunction influences the clinical manifestations of the behavioral symptoms in ALS-FTD; 2) the emotional and behavioral symptoms of bvFTD and ALS-FTD are the same, but ALS-FTD patients come to clinical attention earlier in the course of their FTD than bvFTD patients without ALS; and 3) the emotional and behavioral symptoms of bvFTD and ALS-FTD could differ.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100247"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-12DOI: 10.1016/j.psycr.2025.100246
Jamie Torrance , Jessica Smith , Philip Newall
While most previous adolescent gambling research focuses on the illegal use of age-restricted products, adolescents can also often gamble legally using machines such as coin pushers (aka ‘penny falls’ machines). Using a qualitative case report design, we use an in-depth interview to complement previous findings, which have associated recollected adolescent use of coin pusher machines with levels of adult gambling-related harm. We recruited a 57-year-old male with a history of significant gambling-related harm, whose initiation into gambling involved the adolescent use of coin pusher machines. The interview was audio recorded, transcribed, and analyzed using interpretative phenomenological analysis. Three themes were identified: the structural similarities between coin pushers and traditional gambling formats, the role of proximity and normalization in facilitating progression to riskier gambling, and the participant's suggestions for population-level harm prevention measures. This novel case report highlights how a person's lifelong struggles with severe gambling-related harms began with adolescent exposure to coin pusher machines. Greater awareness of this case could encourage more gamblers to share similar experiences, alongside helping to educate parents and policymakers about the potential harmful consequences of using coin pusher machines.
{"title":"‘I wouldn't have become addicted to fruit machines if it wasn't for coin pushers’: A case report of adolescent coin pusher use leading to lifelong gambling-related harm","authors":"Jamie Torrance , Jessica Smith , Philip Newall","doi":"10.1016/j.psycr.2025.100246","DOIUrl":"10.1016/j.psycr.2025.100246","url":null,"abstract":"<div><div>While most previous adolescent gambling research focuses on the illegal use of age-restricted products, adolescents can also often gamble legally using machines such as coin pushers (aka ‘penny falls’ machines). Using a qualitative case report design, we use an in-depth interview to complement previous findings, which have associated recollected adolescent use of coin pusher machines with levels of adult gambling-related harm. We recruited a 57-year-old male with a history of significant gambling-related harm, whose initiation into gambling involved the adolescent use of coin pusher machines. The interview was audio recorded, transcribed, and analyzed using interpretative phenomenological analysis. Three themes were identified: the structural similarities between coin pushers and traditional gambling formats, the role of proximity and normalization in facilitating progression to riskier gambling, and the participant's suggestions for population-level harm prevention measures. This novel case report highlights how a person's lifelong struggles with severe gambling-related harms began with adolescent exposure to coin pusher machines. Greater awareness of this case could encourage more gamblers to share similar experiences, alongside helping to educate parents and policymakers about the potential harmful consequences of using coin pusher machines.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100246"},"PeriodicalIF":0.0,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-08DOI: 10.1016/j.psycr.2025.100245
Martin Blay , Inès Benmakhlouf , Mario Speranza
Psychotherapy enhanced by psychedelics has recently been found to be helpful for the treatment of several psychiatric disorders, notably depressive disorders. However, it has only been considered scarcely in patients suffering from personality disorders. Here, we report the case of a 37 years-old woman suffering from severe mixed personality disorder and ADHD. Alongside the beginning of her GPM-based psychotherapeutic treatment, and despite our concerns, she started closely monitored psychedelic micro-dosing, using products bought online, punctuated by occasional macro-dosing After one-year of this psychotherapy associated with concomitant independent use of psychedelics, paranoid, narcissistic and borderline personality dimensions were largely improved, as well as emotion regulation, impulsivity, mentalization abilities, and social functioning. Given the actual evidence regarding the efficacy of psychedelics to improve the latter four dimensions, given the patient's reported experience, and despite important limits, we make the hypothesis that the concomitant use of psychedelics has enhanced psychotherapy efficacy. Overall, this case asks the question of the potential usefulness of psychedelics associated with psychotherapy in patients with PD. Further pilot studies should be conducted on this issue.
{"title":"Could psychedelics be useful in the treatment of patients with personality disorder? A case report of psychotherapy with concomitant use of psychedelics","authors":"Martin Blay , Inès Benmakhlouf , Mario Speranza","doi":"10.1016/j.psycr.2025.100245","DOIUrl":"10.1016/j.psycr.2025.100245","url":null,"abstract":"<div><div>Psychotherapy enhanced by psychedelics has recently been found to be helpful for the treatment of several psychiatric disorders, notably depressive disorders. However, it has only been considered scarcely in patients suffering from personality disorders. Here, we report the case of a 37 years-old woman suffering from severe mixed personality disorder and ADHD. Alongside the beginning of her GPM-based psychotherapeutic treatment, and despite our concerns, she started closely monitored psychedelic micro-dosing, using products bought online, punctuated by occasional macro-dosing After one-year of this psychotherapy associated with concomitant independent use of psychedelics, paranoid, narcissistic and borderline personality dimensions were largely improved, as well as emotion regulation, impulsivity, mentalization abilities, and social functioning. Given the actual evidence regarding the efficacy of psychedelics to improve the latter four dimensions, given the patient's reported experience, and despite important limits, we make the hypothesis that the concomitant use of psychedelics has enhanced psychotherapy efficacy. Overall, this case asks the question of the potential usefulness of psychedelics associated with psychotherapy in patients with PD. Further pilot studies should be conducted on this issue.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100245"},"PeriodicalIF":0.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-04DOI: 10.1016/j.psycr.2025.100244
Annabelle M. Mournet, Allison K. Ruork, Evan M. Kleiman, Shireen L. Rizvi
Introduction
Sleep disturbances are a well-established suicide risk factor. This case series represents an investigation into the individual-level associations between objectively measured sleep using actigraphy and fatigue on next-day suicidal ideation, self-harm urges, and desire to be alive.
Methods
This case series utilizes data from seven adults with borderline personality disorder receiving dialectical behavioral therapy (DBT). Participants wore a Phillips HealthBand wearable device to collect actigraphy data and completed ecological momentary assessment (EMA). Data was collected for one week per month for each of the six months of treatment. We conducted a series of individual linear regressions.
Results
For participant 1, fatigue was associated with self-injury urges. Sleep duration and time in bed were predictive of desire to be alive. For participant 3, fatigue was associated with suicidal ideation. Sleep efficiency was predictive of desire to be alive. Participant 5′s WASO was predictive of suicidal ideation and desire to be alive. For participant 6, WASO predicted desire to be alive. For participant 7, fatigue was predictive of desire to be alive.
Discussion
This case series provides evidence that certain aspects of sleep, as measured by actigraphy, is predictive of SI, self-harm urges, and desire to be alive among certain DBT patients. Results points to the importance of examining actigraphy findings on an individual level. Future research should continue to utilize multimodal data to advance understanding of the associations between sleep metrics with STBs, as well as how to continue to best leverage actigraphy data in combination with other methodologies.
{"title":"An actigraphy case series: Sleep disturbance associations with suicidal ideation, self-harm and desire to live","authors":"Annabelle M. Mournet, Allison K. Ruork, Evan M. Kleiman, Shireen L. Rizvi","doi":"10.1016/j.psycr.2025.100244","DOIUrl":"10.1016/j.psycr.2025.100244","url":null,"abstract":"<div><h3>Introduction</h3><div>Sleep disturbances are a well-established suicide risk factor. This case series represents an investigation into the individual-level associations between objectively measured sleep using actigraphy and fatigue on next-day suicidal ideation, self-harm urges, and desire to be alive.</div></div><div><h3>Methods</h3><div>This case series utilizes data from seven adults with borderline personality disorder receiving dialectical behavioral therapy (DBT). Participants wore a Phillips HealthBand wearable device to collect actigraphy data and completed ecological momentary assessment (EMA). Data was collected for one week per month for each of the six months of treatment. We conducted a series of individual linear regressions.</div></div><div><h3>Results</h3><div>For participant 1, fatigue was associated with self-injury urges. Sleep duration and time in bed were predictive of desire to be alive. For participant 3, fatigue was associated with suicidal ideation. Sleep efficiency was predictive of desire to be alive. Participant 5′s WASO was predictive of suicidal ideation and desire to be alive. For participant 6, WASO predicted desire to be alive. For participant 7, fatigue was predictive of desire to be alive.</div></div><div><h3>Discussion</h3><div>This case series provides evidence that certain aspects of sleep, as measured by actigraphy, is predictive of SI, self-harm urges, and desire to be alive among certain DBT patients. Results points to the importance of examining actigraphy findings on an individual level. Future research should continue to utilize multimodal data to advance understanding of the associations between sleep metrics with STBs, as well as how to continue to best leverage actigraphy data in combination with other methodologies.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100244"},"PeriodicalIF":0.0,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 2","pages":"Article 100263"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146688255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 2","pages":"Article 100298"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146688259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 2","pages":"Article 100273"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146688263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100252"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146822517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100259"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146822532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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