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Effects of transcranial direct current stimulation on different cognitive domains in Alzheimer's disease: a meta-study. 经颅直流电刺激对阿尔茨海默病不同认知领域的影响:一项荟萃研究。
Pub Date : 2024-09-01 Epub Date: 2024-07-10 DOI: 10.1111/psyg.13158
Xintong Li, Yue Dou, Bin Xiao, Yuming Chen

Background: Numerous studies have investigated the potential effects of transcranial direct current stimulation (tDCS) on improving symptoms related to Alzheimer's disease (AD). However, these studies have produced inconsistent results, leading to a need for further investigation.

Methods: A comprehensive search was conducted, including articles published from the initial availability date to 5 April 2024. The extracted study data were analyzed using STATA 12.0 software. The standard mean difference (SMD) and a 95% confidence interval (CI) were calculated to assess the effects of tDCS.

Results: A total of 18 studies assessing the effects of tDCS on AD were included in the study. The study revealed that tDCS has an immediate positive impact on general cognitive, executive, language, and visuospatial function. However, the study did not observe any other significant effect of tDCS treatment on improvements in brain function, including long-term effects on general cognitive, attention, language, and memory function, as well as immediate effects on attention and memory function.

Conclusions: In conclusion, the study suggests that tDCS may be a promising intervention for improving the cognitive function of patients with AD. However, given the complex and multifactorial nature of AD, further well-designed studies with larger sample sizes are necessary to clarify the effectiveness of tDCS and determine the optimal combination of tDCS parameters.

背景:许多研究调查了经颅直流电刺激(tDCS)对改善阿尔茨海默病(AD)相关症状的潜在作用。然而,这些研究的结果并不一致,因此需要进一步调查:方法:进行了一次全面检索,包括从最初可用日期到 2024 年 4 月 5 日发表的文章。提取的研究数据使用 STATA 12.0 软件进行分析。计算标准平均差(SMD)和 95% 置信区间(CI)来评估 tDCS 的效果:研究共纳入了 18 项评估 tDCS 对注意力缺失症影响的研究。研究显示,tDCS 对一般认知、执行、语言和视觉空间功能有立竿见影的积极影响。然而,研究并未观察到 tDCS 治疗对大脑功能改善的其他显著影响,包括对一般认知、注意力、语言和记忆功能的长期影响,以及对注意力和记忆功能的即时影响:总之,该研究表明,tDCS 可能是一种有希望改善注意力缺失症患者认知功能的干预方法。然而,鉴于注意力缺失症的复杂性和多因素性,有必要进一步开展设计合理、样本量更大的研究,以明确 tDCS 的有效性,并确定 tDCS 参数的最佳组合。
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引用次数: 0
Donepezil as a safe alternative treatment after maculo-papular eruption related to rivastigmine in Lewy body disease: a case report and pharmacovigilance data. 多奈哌齐作为路易体病中与利巴斯的明相关的黄斑丘疹后的一种安全替代治疗方法:病例报告和药物警戒数据。
Pub Date : 2024-09-01 Epub Date: 2024-07-25 DOI: 10.1111/psyg.13166
Margot Chouchana, Sylvine Pinel, Hester Colboc, Angele Soria, Geraldine Buard, Clément Delage, Vanessa Bloch, Matthieu Lilamand
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引用次数: 0
Non-pharmacological management of wandering in persons with dementia: an integrative review. 对痴呆症患者走失的非药物治疗:综合综述。
Pub Date : 2024-09-01 Epub Date: 2024-08-08 DOI: 10.1111/psyg.13173
Sojung Park, Yaelim Lee

Background: Wandering behaviour affects a significant portion of dementia patients, ranging from 15% to 80%, presenting a serious safety concern and adding to caregivers' burden. Recent studies emphasise the effectiveness of non-pharmacological interventions over pharmacological ones due to their minimal side effects. Consequently, in current literature there has been a surge of interest in exploring non-pharmacological methods for managing wandering.

Purpose: This integrative literature review aims to deepen comprehension of wandering behaviour, presents recent studies on non-pharmacological approaches, and inspires further research in this field.

Methods: Electronic data collection spanned from 2019 to 2024, sourcing 20 relevant articles from PubMed and Scopus databases using search terms such as 'dementia', 'Alzheimer's disease', 'wandering', and 'management'. A thematic analysis methodology was employed to identify non-pharmacological treatment themes for managing wandering. This approach involves scrutinising and synthesising themes within the dataset. Qualitative data analysis focused on significant phrases and keywords, grouping them to derive relevant themes.

Results: Recent literature extensively explores non-pharmacological methods for managing wandering. These include understanding behaviours, identifying and targeting high-risk groups, facilitating safe wandering, addressing environmental factors, promoting exercise and activity, and offering caregiver support.

Conclusions: This study significantly advances understanding of wandering behaviour and highlights recent research on non-pharmacological interventions. The findings suggest the potential for providing safe and effective treatment to wandering dementia patients, thereby alleviating stress for both patients and caregivers.

背景:游走行为影响着很大一部分痴呆症患者,比例从 15%到 80%不等,是一个严重的安全问题,也加重了护理人员的负担。最近的研究强调,非药物干预措施比药物干预措施更有效,因为它们的副作用最小。因此,在目前的文献中,人们对探索管理走失的非药物方法产生了浓厚的兴趣。目的:这篇综合性文献综述旨在加深对走失行为的理解,介绍最近关于非药物方法的研究,并启发在这一领域的进一步研究:电子数据收集时间跨度为2019年至2024年,使用 "痴呆症"、"阿尔茨海默病"、"走失 "和 "管理 "等检索词从PubMed和Scopus数据库中收集了20篇相关文章。我们采用了主题分析方法来确定管理走失的非药物治疗主题。这种方法包括对数据集中的主题进行仔细检查和综合。定性数据分析的重点是重要的短语和关键词,将其分组以得出相关主题:最近的文献广泛探讨了管理走失的非药物方法。这些方法包括了解行为、识别并锁定高危人群、促进安全徘徊、解决环境因素、促进运动和活动以及提供护理支持:这项研究极大地促进了人们对流浪行为的了解,并突出强调了有关非药物干预措施的最新研究。研究结果表明,有可能为徘徊的痴呆症患者提供安全有效的治疗,从而减轻患者和护理人员的压力。
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引用次数: 0
Assessment of the relation between depression, frailty, nutrition and quality of life among older adults: findings from a cross-sectional study in Greece. 评估老年人抑郁、虚弱、营养和生活质量之间的关系:希腊一项横断面研究的结果。
Pub Date : 2024-09-01 Epub Date: 2024-06-26 DOI: 10.1111/psyg.13160
Chrysoula Argyriou, Ioanna Dimitriadou, Maria Saridi, Aikaterini Toska, Maria Lavdaniti, Evangelos C Fradelos

Background: Quality of life (QOL) among older adults is a crucial aspect of geriatric care, particularly in the context of global demographic shifts toward ageing societies. Understanding the determinants of QOL in older adults is essential for developing effective interventions to promote well-being in this population.

Methods: This cross-sectional study conducted in Greece aimed to investigate the complex relationship between depression, frailty, nutritional status, and QOL on 90 older adults (aged ≤65). Assessment instruments including the World Health Organization Quality of Life (WHOQoL)-BREF questionnaire, Geriatric Depression Scale (GDS), Clinical Frailty Scale (CFS), and Mini Nutritional Assessment (MNA) were utilised to evaluate various dimensions of QOL, depressive symptoms, frailty, and nutritional status.

Results: The study revealed significant negative correlations between depression and frailty with all domains of QOL (P < 0.05), indicating that higher levels of depressive symptoms and frailty were associated with lower QOL across physical, psychological, social, and environmental dimensions. Conversely, positive correlations were found between nutritional status and all QOL domains (P < 0.05), suggesting that better nutritional status was linked to higher QOL. Multivariate logistic regression analysis further demonstrated associations between nutritional status and participant characteristics, with females being more likely to be malnourished (odds ratio (OR) = 6.56, P = 0.013), while better health status (OR = 0.34, P = 0.486) and marital status (OR = 0.02, P = 0.019) were protective against malnutrition.

Conclusion: These findings underscore the interconnectedness of depression, frailty, and nutritional status in shaping QOL among individuals. Holistic interventions targeting mental health, physical vulnerability, and nutritional well-being are essential for promoting overall well-being and functional outcomes in this population.

背景:老年人的生活质量(QOL)是老年护理的一个重要方面,尤其是在全球人口向老龄化社会转变的背景下。了解老年人生活质量的决定因素对于制定有效的干预措施以提高这一人群的幸福感至关重要:这项横断面研究在希腊进行,旨在调查 90 名老年人(年龄小于 65 岁)的抑郁、虚弱、营养状况和 QOL 之间的复杂关系。评估工具包括世界卫生组织生活质量(WHOQoL)-BREF问卷、老年抑郁量表(GDS)、临床虚弱量表(CFS)和迷你营养评估(MNA),用于评估QOL、抑郁症状、虚弱和营养状况的各个方面:研究结果表明,抑郁症状和虚弱程度与所有 QOL 领域之间均存在明显的负相关关系(P这些发现强调了抑郁、虚弱和营养状况在影响个人 QOL 方面的相互关联性。针对心理健康、身体虚弱和营养状况的综合干预措施对于促进这类人群的整体健康和功能结果至关重要。
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引用次数: 0
The effects of spiritual wellbeing on life satisfaction in hematologic cancer patients aged 65 and older in Turkey: mediating role of hope. 精神健康对土耳其 65 岁及以上血液肿瘤患者生活满意度的影响:希望的中介作用。
Pub Date : 2024-09-01 Epub Date: 2024-08-11 DOI: 10.1111/psyg.13175
Gülcan Bahcecioglu Turan, Zülfünaz Özer, Safiye YanmıŞ

Background: The mediating role of hope in the effects of spiritual wellbeing on life satisfaction in elderly haematologic cancer patients in Turkey was investigated in the present study.

Methods: The study was conducted in a descriptive, cross-sectional and correlational design. The study was conducted with 150 patients aged 65 and older who were diagnosed with haematologic cancer and who were referred to a university hospital haematology clinic and outpatient clinic. Research data were collected with Descriptive Information Form, Dispositional Hope Scale (DHS), Spiritual Well-being Scale (FACIT-Sp-12) and Satisfaction with Life Scale (SWLS).

Results: FACIT-Sp-12 score was 37.25 ± 7.29; DHS score was 40.42 ± 8.29, SWLS score was 16.24 ± 8.79. FACIT-Sp-12 (β = 0.668) and DHS (β = 0.226) were found to affect SWLS positively. In terms of the effect of FACIT-Sp-12 on SWLS, DHS has a mediating role and makes the positive effect of FACIT-Sp-12 on SWLS stronger (β = 0.771).

Conclusions: Spiritual wellbeing levels of the participants in our study were found to be high, while their levels of satisfaction with life and hope were found to be moderate. It was also concluded that spiritual wellbeing had a direct effect on satisfaction with life and an indirect effect through the mediating role of hope.

背景:本研究探讨了希望在精神健康对土耳其老年血液肿瘤患者生活满意度的影响中所起的中介作用:研究采用描述性、横断面和相关性设计。研究对象为 150 名 65 岁及以上确诊为血液肿瘤的患者,他们被转诊至一家大学医院的血液学诊所和门诊部。研究数据通过描述性信息表、性格希望量表(DHS)、精神健康量表(FACIT-Sp-12)和生活满意度量表(SWLS)收集:FACIT-Sp-12得分(37.25 ± 7.29),DHS得分(40.42 ± 8.29),SWLS得分(16.24 ± 8.79)。结果发现,FACIT-Sp-12(β = 0.668)和 DHS(β = 0.226)对 SWLS 有积极影响。就 FACIT-Sp-12 对 SWLS 的影响而言,DHS 起着中介作用,使 FACIT-Sp-12 对 SWLS 的积极影响更强(β = 0.771):结论:我们的研究发现,参与者的精神幸福感水平较高,而他们对生活的满意度和希望水平适中。研究还得出结论,精神健康对生活满意度有直接影响,并通过希望的中介作用产生间接影响。
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引用次数: 0
Effects of a case management-based intervention on non-motor risk factors for falls in older people with history of falls: a randomised clinical trial. 基于个案管理的干预措施对有跌倒史的老年人非运动性跌倒风险因素的影响:随机临床试验。
Pub Date : 2024-09-01 Epub Date: 2024-07-22 DOI: 10.1111/psyg.13167
João Vitor Businaro Florido, Maria Joana Duarte Caetano, Ana Luísa Janducci, Mariana Ignácio Sossai, Ana Laura Oliveira Dias, Karina Gramani-Say, Juliana Hotta Ansai

Background: Falls are directly related to morbidity and mortality of older people. Multifactorial approaches that are individualised and based on fall risk factors are necessary. This study aims to verify the effects of a case management-based intervention on non-motor risk factors for falls in community-dwelling older people with a history of falls.

Methods: The intervention applied a multidimensional assessment of risk factors for falls, a discussion about the identified risk factors, the preparation of an individualised plan with the participant, and the application, monitoring and review of the plan.

Results: There was a significant interaction between groups and assessments only in the visuospatial domain (P = 0.031). After simple main effects analysis, differences between groups and assessments were not significant, although there was a tendency of worse visuospatial performance in the control group in the follow-up assessment (P = 0.099). There were no significant differences between groups or between assessments in other variables.

Conclusion: The intervention has the potential to maintain non-motor risk factors for falls in community-dwelling older people with a history of falls. However, more clinical trials are needed to prove its effects.

背景:跌倒与老年人的发病率和死亡率直接相关。有必要根据跌倒风险因素采取个性化的多因素方法。本研究旨在验证基于个案管理的干预措施对有跌倒史的社区老年人跌倒的非运动风险因素的影响:干预措施包括对跌倒风险因素进行多维度评估,讨论已识别的风险因素,与参与者一起制定个性化计划,以及实施、监测和审查该计划:只有在视觉空间领域,组别与评估之间存在明显的交互作用(P = 0.031)。经过简单的主效应分析,虽然对照组在后续评估中的视觉空间表现有变差的趋势(P = 0.099),但组间和评估之间的差异并不显著。其他变量在组间和评估间均无明显差异:结论:干预措施有可能维持有跌倒史的社区老年人的非运动性跌倒风险因素。然而,还需要更多的临床试验来证明其效果。
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引用次数: 0
Effects of policy interventions on psychotropic polypharmacy in Japanese older adults. 政策干预对日本老年人精神药物多药滥用的影响。
Pub Date : 2024-09-01 Epub Date: 2024-07-15 DOI: 10.1111/psyg.13165
Masahiro Takeshima, Kazuhisa Yoshizawa, Masaya Ogasawara, Mizuki Kudo, Yu Itoh, Naoko Ayabe, Kazuo Mishima
{"title":"Effects of policy interventions on psychotropic polypharmacy in Japanese older adults.","authors":"Masahiro Takeshima, Kazuhisa Yoshizawa, Masaya Ogasawara, Mizuki Kudo, Yu Itoh, Naoko Ayabe, Kazuo Mishima","doi":"10.1111/psyg.13165","DOIUrl":"10.1111/psyg.13165","url":null,"abstract":"","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":" ","pages":"1176-1179"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11578015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The clinical application value of psychological nursing intervention for patients with prostatic hyperplasia during treatment. 前列腺增生患者治疗期间心理护理干预的临床应用价值。
Pub Date : 2024-09-01 Epub Date: 2024-08-08 DOI: 10.1111/psyg.13172
Tingting Lin, Linlin Zhong

Objective: To investigate the therapeutic utility of psychological nursing interventions for prostatic hyperplasia clients while they are receiving therapy.

Methods: Clinical data of 110 patients with prostate group hyperplasia who underwent treatment in our hospital were collected and analysed retrospectively, and the selected period was from October 2021 to October 2023. The 110 cases of prostate group hyperplasia patients were divided into a research group and a control group according to the different methods of care, and each group had 55 cases each. The research group received psychological nursing intervention based on the conventional nursing care given to the control group. The total treatment compliance rate and contentment with nursing were contrasted between the research and control groups, and changes in the Self Rating Anxiety Scale (SAS) score, Self Rating Depression Scale (SDS) score, Health Survey Short Form score, and sleep problems were observed between the research group and the control group.

Results: The research group's overall compliance rate was 94.55% (52/53), a substantial increase over the control group's rate, 69.09% (38/55), P < 0.01. Following nursing, the research group's SAS and SDS scores were considerably more reduced than those of the control group, and both groups' scores were substantially lower than they were prior to nursing (P < 0.05).

Conclusion: This retrospective study found that psychological nursing intervention applied to patients with prostatic hyperplasia can effectively improve the patient's compliance with treatment, effectively reduce the occurrence of negative emotions, improve the patient's quality of life, and improve sleep problems. In addition, psychological nursing intervention can effectively alleviate the tension between nurses and patients, and is worthy of clinical application.

摘要研究前列腺增生患者在接受治疗期间心理护理干预的治疗作用:收集并回顾性分析在我院接受治疗的110例前列腺增生患者的临床资料,选取时间为2021年10月至2023年10月。将110例前列腺增生患者按照不同的护理方法分为研究组和对照组,每组各55例。研究组在对照组常规护理的基础上进行心理护理干预。对比研究组和对照组的总治疗依从率和护理满意度,观察研究组和对照组的焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、健康调查简表评分和睡眠问题的变化:结果:研究组的总体达标率为 94.55%(52/53),比对照组的 69.09%(38/55)有了大幅提高:该回顾性研究发现,对前列腺增生患者实施心理护理干预,可有效提高患者的治疗依从性,有效减少患者负性情绪的发生,提高患者的生活质量,改善患者的睡眠问题。此外,心理护理干预还能有效缓解护患之间的紧张关系,值得临床应用。
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引用次数: 0
Reflecting on the promising role of transcranial direct current stimulation in Alzheimer's disease. 反思经颅直流电刺激在阿尔茨海默病中的前景。
Pub Date : 2024-09-01 Epub Date: 2024-08-06 DOI: 10.1111/psyg.13170
Lien-Chung Wei, En-Liang Wu
{"title":"Reflecting on the promising role of transcranial direct current stimulation in Alzheimer's disease.","authors":"Lien-Chung Wei, En-Liang Wu","doi":"10.1111/psyg.13170","DOIUrl":"10.1111/psyg.13170","url":null,"abstract":"","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":" ","pages":"1184"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141899140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between the level of social participation and depressive symptoms among older Japanese adults: a cross-sectional survey. 日本老年人的社会参与程度与抑郁症状之间的关系:一项横断面调查。
Pub Date : 2024-09-01 Epub Date: 2024-07-16 DOI: 10.1111/psyg.13163
Takahiro Shimoda, Kouki Tomida, Chika Nakajima, Ayuka Kawakami, Hiroyuki Shimada

Background: Social participation is recommended for older adults to remain actively involved in daily life. Social participation is a broad concept, ranging from 'interacting with others without doing a specific activity with them' to 'actively contributing to society.' However, previous studies have not taken into account the components of social participation. Depressive symptoms are significant outcomes in older adults. Social participation mitigates these risks owing to its association with reduced mortality and enhanced quality of life. This study aimed to examine the association between the level of social participation and depressive symptoms in community-dwelling older adults.

Methods: We included 17 040 individuals aged ≥65 years. Social participation was categorised into Level 3, interacting with others without doing a specific activity with them; Level 4, engaging in an activity with others; Level 5, helping others; and Level 6, contributing to society, based on a previous study by Levasseur et al. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale. Logistic regression models were used to examine the association between the level of social participation and depressive symptoms.

Results: Overall, 15 069 older adults met the inclusion criteria. A higher level of social participation was associated with lower odds ratios (ORs) for depressive symptoms (Level 6 = OR: 0.43, 95% confidence interval (CI): 0.37-0.50; Level 5 = OR: 0.50, 95% CI: 0.41-0.60; and Level 4 = OR: 0.60, 95% CI: 0.52-0.69). Subgroup analyses based on age and sex yielded similar results across all participants.

Conclusions: Among older adults in Japan, a higher level of social participation was associated with lower rates of depressive symptoms. The relationship between depressive symptoms and the levels of social participation may help develop measures to reduce or prevent depressive symptoms in older adults.

背景:建议老年人积极参与社会生活。社会参与是一个宽泛的概念,从 "与他人互动但不与他们一起进行特定活动 "到 "积极为社会做贡献"。然而,以往的研究并没有考虑到社会参与的组成部分。抑郁症状对老年人的影响很大。社会参与可降低这些风险,因为它与降低死亡率和提高生活质量有关。本研究旨在探讨社区老年人的社会参与程度与抑郁症状之间的关系:我们纳入了 17 040 名年龄≥65 岁的老年人。根据 Levasseur 等人之前的研究,社会参与分为 3 级:与他人互动,但不与他人一起进行特定活动;4 级:与他人一起参与活动;5 级:帮助他人;6 级:为社会做出贡献。抑郁症状采用 15 项老年抑郁量表进行评估。采用逻辑回归模型来研究社会参与程度与抑郁症状之间的关系:共有 15 069 名老年人符合纳入标准。较高的社会参与度与较低的抑郁症状几率比(ORs)相关(6级=OR:0.43,95%置信区间(CI):0.37-0.50;5级=OR:0.50,95%置信区间(CI):0.41-0.60;4级=OR:0.60,95%置信区间(CI):0.52-0.69)。基于年龄和性别的分组分析结果与所有参与者的结果相似:在日本的老年人中,较高的社会参与度与较低的抑郁症状发生率有关。抑郁症状与社会参与程度之间的关系可能有助于制定减少或预防老年人抑郁症状的措施。
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引用次数: 0
期刊
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society
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