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Squamotransitional Cell Carcinoma of the Uterine Cervix with Ovarian Metastasis and Benign Brenner Tumor: A Case Report 宫颈鳞状移行细胞癌合并卵巢转移及良性勃勒纳瘤1例报告
Pub Date : 2023-11-13 DOI: 10.3390/reports6040054
Angel Yordanov, Milen Karaivanov, Ivan Ivanov, Stoyan Kostov, Venelina Todorova, Ilko Iliev, Eva Tzoneva, Diana Strateva
Introduction: Cervical cancer is the fourth most common malignancy in women and the fourth leading cause of death among women. The main histological types of cervical cancer are squamous cell carcinoma—75% of all cases; adenocarcinoma—10–25%; and all other rare variants including adenosquamous carcinoma and neuroendocrine carcinoma. Squamotransitional cervical cancer is an extremely rare and poorly studied subtype of squamous cell carcinoma. Case report: We present a case of a 64-year-old female patient with early-stage squamotransitional carcinoma. A metastasis was observed in the left ovary and the left fallopian tube and a benign Brenner tumor in the right ovary. Discussion: Although it is believed that this cervical cancer subtype shares the same risk factors and prognosis as squamous cell carcinoma, it is more likely to metastasize and recur. It is not unusual for spread to exist within nearby structures like the cervix and adnexa. It is impossible to tell which is the predominant focus from the immunoprofile of the lesions. Practically speaking, the best course of action in these situations is to rule out the presence of a primary tumor in the urinary tract before clarifying the condition of the cervix, uterus, and adnexal tissues. The presence of a Brenner tumor raises the possibility of a connection between the tumor’s differentiation from a cell population and potential urothelial differentiation. Conclusion: Squamotransitional cervical cancer is a rare tumor with a poorly studied clinical behavior. Despite a shortage of information in the literature, it should be regarded as a more aggressive variety of squamous cell carcinoma and, as such, should be treated and followed up more aggressively. This case is the first described with involvement of the cervix, endometrium, and adnexal structures and a concomitant Brenner tumor.
引言:宫颈癌是妇女中第四大最常见的恶性肿瘤,也是妇女死亡的第四大原因。宫颈癌的主要组织学类型是鳞状细胞癌,占所有病例的75%;腺癌- 10 - 25%;以及所有其他罕见的变异包括腺鳞癌和神经内分泌癌。鳞状移行性宫颈癌是一种极为罕见且研究较少的鳞状细胞癌亚型。病例报告:我们报告一例64岁女性早期鳞状移行癌。左侧卵巢及左侧输卵管有转移,右侧卵巢有良性勃勒纳瘤。讨论:虽然认为该宫颈癌亚型与鳞状细胞癌具有相同的危险因素和预后,但它更容易转移和复发。在宫颈和附件等附近的结构中扩散并不罕见。这是不可能告诉哪是主要焦点从免疫档案的病变。实际上,在这些情况下,最好的做法是在明确子宫颈、子宫和附件组织的状况之前,排除泌尿道中原发肿瘤的存在。勃勒纳瘤的存在提出了肿瘤从细胞群分化和潜在的尿路上皮分化之间的联系的可能性。结论:宫颈鳞状移行性宫颈癌是一种罕见的肿瘤,临床行为研究较少。尽管文献资料缺乏,但应将其视为一种更具侵袭性的鳞状细胞癌,因此应更积极地治疗和随访。本病例是第一例累及子宫颈、子宫内膜和附件结构并伴有勃勒纳瘤的病例。
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引用次数: 0
Prophylaxis Failure and Successful Management of Delayed-Onset Malaria with Renal Complications: A Case Report with Oral Artemether-Lumefantrine Treatment 延迟性疟疾伴肾脏并发症的预防失败和成功治疗:口服蒿甲醚-氨苯曲明治疗1例报告
Pub Date : 2023-11-08 DOI: 10.3390/reports6040053
Ilir Tolaj, Gramoz Bunjaku, Murat Mehmeti, Yllka Begolli
This case report presents a critical clinical scenario involving a 55-year-old patient who developed severe Plasmodium falciparum malaria with renal complications despite receiving doxycycline prophylaxis while traveling in a malaria-endemic region. The case emphasizes the potential failure of doxycycline prophylaxis and highlights the importance of considering malaria in patients with a history of travel to endemic areas, even if they have adhered to prophylactic treatment. The patient’s clinical presentation included fever, extreme fatigue, and loss of consciousness, leading to hospitalization. Laboratory findings revealed severe anemia, elevated liver enzymes, and impaired renal function, consistent with the criteria for severe malaria. The diagnosis was confirmed by the presence of Plasmodium falciparum parasites on thin blood smears. Due to limited access to parenteral antimalarial medications in Kosovo, the patient received oral artemether-lumefantrine, resulting in clinical improvement. Supportive care and dialysis played a vital role in the patient’s recovery. This case report underscores the need for increased awareness of prophylaxis failure, the challenges of managing severe malaria in non-endemic countries, and the importance of timely and appropriate interventions to improve outcomes in severe malaria cases, particularly those with renal involvement.
本病例报告提出了一个关键的临床情景,涉及一名55岁患者,尽管在疟疾流行地区旅行时接受了强力霉素预防治疗,但仍出现了严重的恶性疟原虫疟疾并伴有肾脏并发症。该病例强调了强力霉素预防的潜在失败,并强调了在有去过流行地区旅行史的患者中考虑疟疾的重要性,即使他们坚持了预防性治疗。患者的临床表现包括发烧、极度疲劳和意识丧失,导致住院。实验室结果显示严重贫血、肝酶升高和肾功能受损,符合严重疟疾的标准。薄血涂片上发现恶性疟原虫,证实了诊断。在科索沃,由于获得肠外抗疟疾药物的机会有限,患者接受了口服蒿甲醚-氨苯曲明治疗,导致临床改善。支持性护理和透析在患者的康复中发挥了至关重要的作用。本病例报告强调有必要提高对预防失败的认识、在非疟疾流行国家管理严重疟疾的挑战,以及及时和适当干预措施以改善严重疟疾病例,特别是肾脏受累病例预后的重要性。
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引用次数: 0
Digital Workflow in Full Mouth Rehabilitation with Immediate Loading, Intraoral Welding and 3D-Printed Reconstructions in a Periodontal Patient: A Case Report 数字工作流程在全口康复与即时加载,口腔内焊接和3d打印重建牙周患者:一个案例报告
Pub Date : 2023-11-01 DOI: 10.3390/reports6040052
Adam Nowicki, Karolina Osypko
Background: Complex implant reconstructions in patients with residual dentition due to periodontitis is a challenging task in many aspects. Methods: This study shows a full digital workflow combining 3D printing, guided implant placement, intraoral scanning and welding with immediate loading and digital smile design. An analog impression was taken to validate the passive fit of final restorations. The whole treatment plan was divided into three stages. The first stage included an intraoral scan of baseline dentition, and then the extraction of all teeth was performed, implanting four temporary implants and providing the patient with removable temporary prosthesis. The second stage was to scan the removable temporaries, implanting 10 implants and multi-unit abutments (MUA), and create a rigid construction via the intraoral welding of titanium bar and by fixing it to the 3D-printed temporary reconstructions (designed with DSD) as a form of immediate loading. The third stage included the scanning of screw-retained temporary reconstructions, then scanning from the MUA level and creating final reconstruction. Results: The presented workflow enabled the delivery of some sort of restoration to the patient at every moment of the treatment and to sustain the required esthetic effect with decent comfort of use even in the early stages. Conclusions: A full digital workflow is a reliable treatment method even in complex cases.
背景:牙周炎遗留牙列患者的复杂种植体重建在许多方面都是一项具有挑战性的任务。方法:本研究展示了3D打印、引导种植体植入、口腔内扫描和焊接即时加载以及数字微笑设计相结合的全数字化工作流程。采用模拟印模来验证最终修复体的被动拟合。整个治疗计划分为三个阶段。第一阶段包括基线牙列的口腔内扫描,然后拔出所有牙齿,种植4个临时种植体,并为患者提供可移动的临时假体。第二阶段是扫描可移动的临时体,植入10个种植体和多单元基台(MUA),并通过钛棒的口内焊接,将其固定在3d打印的临时重建体(用DSD设计)上,作为一种即时加载形式,创建一个刚性结构。第三阶段包括扫描螺钉保留的临时重建,然后从MUA水平扫描并创建最终重建。结果:所提出的工作流程能够在治疗的每一刻为患者提供某种修复,并且即使在早期阶段也能维持所需的美学效果和良好的使用舒适性。结论:完整的数字化工作流程是治疗复杂病例的可靠方法。
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引用次数: 0
Enhanced Gait Recovery in Chronic Post-COVID-19 Stroke: The Role of Combined Physical Rehabilitation 增强covid -19后慢性卒中的步态恢复:联合物理康复的作用
Pub Date : 2023-10-20 DOI: 10.3390/reports6040051
Hunor Pál Fodor, Hunor Dávid, Attila Czont, Ildikó Miklóssy, Kálmán-Csongor Orbán, Gyöngyi Tar, Abony Fodor, Zita Kovács, Beáta Albert, Pál Salamon
Background: Rehabilitation programs applied in cases of COVID-19-related stroke should counteract not only the effects of the stroke but also the effects of long-term COVID-19. As the molecular processes underlying these cases are still not fully understood, and evidence-based clinical outcomes are scarcely documented, there is a valid need to gather information and develop rehabilitation strategies for these patients. The risks, already clarified in the case of stroke, need to be assessed taking into account the coincidence of the two diseases. Endothelial injuries and emboli that develop after the hypercoagulable state of COVID-19 may take longer to heal, and complications may occur during exercise. This case study attempts to determine what the rehabilitation of a COVID-19-related stroke patient should include. The participant was a 64-year-old male with ischemic right middle cerebral artery stroke, left-side hemiplegia, and middle cerebral artery stenosis, and the CT showed a well-defined area of hypoattenuation in the basal ganglia territory involving the right lentiform nucleus, the anterior and posterior limbs of the internal capsule, and the dorsal part of the external capsule. His NIHSS score was 14, and he registered 15 points on the Barthel index. The patient had a COVID-19 infection two weeks before the stroke event. Methods: Conventional physical therapy was combined with adaptive ballistic strength training, a high-intensity interval training regimen, and manual treatment for myofascial release throughout the chronic recovery phase. Our primary goals were gait rehabilitation, muscle strengthening, weakness management, as well as spasticity reduction, while three different rehabilitation approaches were adopted in a single rehabilitation program to improve the outcome and long-term functional recovery of the patient. Results: The patient progressed in almost every aspect of the assessment criteria. This combined approach’s main success was improved gait speed, gait quality, and improved cardiovascular fitness. Take-away message: In the case of a stroke caused by COVID-19, where the endothelium cells are compromised, HIIT may be questionable due to the poor vascular condition. Based on our results, the low-volume HIIT approach proved appropriate and effective.
背景:在COVID-19相关卒中病例中应用的康复方案不仅要抵消卒中的影响,还要抵消COVID-19的长期影响。由于这些病例背后的分子过程仍未被完全理解,基于证据的临床结果几乎没有记录,因此有必要为这些患者收集信息并制定康复策略。在中风的情况下,风险已经明确,需要考虑到这两种疾病的巧合来评估。在COVID-19高凝状态后发生的内皮损伤和栓塞可能需要更长的时间才能愈合,并且在运动过程中可能发生并发症。本案例研究试图确定covid -19相关中风患者的康复应包括哪些内容。参与者男性,64岁,右侧大脑中动脉缺血性卒中,左侧偏瘫,大脑中动脉狭窄,CT示基底节区明显低衰减区,累及右侧晶状体核、内囊前后肢、外囊背侧。他的NIHSS分数是14分,他在巴特尔指数上的得分是15分。该患者在中风前两周感染了COVID-19。方法:常规物理治疗结合适应性弹道力量训练,高强度间歇训练方案,并在整个慢性恢复期进行肌筋膜释放的手工治疗。我们的主要目标是步态康复、肌肉强化、无力管理和痉挛减少,同时在单一康复计划中采用三种不同的康复方法来改善结果和患者的长期功能恢复。结果:患者在各项评估指标上均取得进展。这种联合方法的主要成功是改善了步态速度、步态质量和改善了心血管健康。结论:在COVID-19引起中风的情况下,内皮细胞受损,由于血管状况不佳,HIIT可能值得怀疑。根据我们的结果,小容量HIIT方法被证明是适当和有效的。
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引用次数: 0
Cardiopulmonary Resuscitation-Related Head Trauma: A Case Report 心肺复苏相关头部创伤1例报告
Pub Date : 2023-10-19 DOI: 10.3390/reports6040050
Ilina Brainova, Pavel Timonov, Antoaneta Fasova, Alexandar Alexandrov
Introduction: In all cases of cardiac arrest, adequate cardiopulmonary resuscitation (CPR) performance is crucial for survival. There are differences between the performances of CPR in pediatric cases compared to CPR in adults. In all cases in which CPR is needed, there is a possibility for the occurrence of CPR-related traumatic injuries. Aims and methods: We used all available forensic examination methods in order to provide objective forensic investigation conclusions and feedback to clinicians. Results: We present an untypical case of head trauma with intracranial bleeding caused via CPR-related traumatic injury. Although it is not connected with the mechanism and genesis of death, it should be noted as being practically casuistic. The child had a severe congenital heart malformation. The surgical team decided that surgery was absolutely necessary. Complications developed in the postoperative period. On the second postoperative day, cardiac arrest occurred, CPR was performed, and the girl survived for 15 minuntil there was a second cardiac arrest. A second CPR was performed, but she died. During the forensic autopsy, with the exception of expected findings, head bruising and intracranial bleeding were registered. Conclusion: The forensic conclusion was that the head trauma was caused accidentally during CPR due to the non-voluntary impact of the head with respect to the background of anticoagulant therapy, which was one possible factor for the massive bleeding.
在所有心脏骤停的病例中,适当的心肺复苏(CPR)表现对生存至关重要。与成人心肺复苏术相比,儿童心肺复苏术的表现存在差异。在所有需要心肺复苏术的病例中,都有可能发生与心肺复苏术相关的创伤性损伤。目的和方法:利用现有的法医检验方法,为临床医生提供客观的法医调查结论和反馈。结果:我们报告了一例非典型的颅脑外伤合并颅内出血的病例。虽然它与死亡的机制和起源没有联系,但应该指出它实际上是诡辩的。这孩子有严重的先天性心脏畸形。手术小组认为手术是绝对必要的。术后出现并发症。术后第二天,发生心脏骤停,进行了心肺复苏术,女孩存活了15分钟,直到第二次心脏骤停。医生给她做了第二次心肺复苏术,但她还是死了。在法医尸检期间,除了预期的发现外,还记录了头部瘀伤和颅内出血。结论:法医学结论认为,在抗凝治疗的背景下,由于头部的非自愿撞击,是心肺复苏术中意外造成的头部创伤,这可能是导致大出血的原因之一。
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引用次数: 0
Challenges in Assessing Aphasia in Congenital Blind Patients: A Case Report 先天性失明患者失语评估的挑战:1例报告
Pub Date : 2023-10-11 DOI: 10.3390/reports6040049
Maria Grazia Nicoletta, Francesco Riganello, Lucia Francesca Lucca, Maria Daniela Cortese
This case report focuses on assessing aphasia in a congenitally blind patient with an ischemic lesion using the Aachener Aphasia Test. The method involved adapting existing assessment tools to the patient, integrating Braille as an accessible technology, and incorporating the patient’s family for emotional support and for the identification of patient-specific communication strategies. The assessment revealed patient strengths in areas such as articulation, prosody, and repetition skills, but also exposed challenges in semantic and syntactic structures. However, the unavailability to assess and score naming and comprehension limited a full assessment of the patient’s language abilities. The findings underscore the need for flexible, tailored assessment strategies and collaborative approaches involving healthcare professionals and families. Moreover, it suggests a considerable research gap and a need for standard tools to assess blind patients with aphasia comprehensively. This case report contributes to the limited knowledge of assessing aphasia in blind individuals and calls for further research in this area to refine and expand the available tools and strategies.
本病例报告的重点是评估失语症在先天性失明患者与缺血性病变使用Aachener失语症测试。该方法包括调整现有的评估工具以适应患者,将盲文作为一种可访问的技术,并结合患者家庭的情感支持和确定患者特定的沟通策略。该评估显示了患者在发音、韵律和重复技能等方面的优势,但也暴露了他们在语义和句法结构方面的挑战。然而,无法评估和评分命名和理解限制了对患者语言能力的全面评估。研究结果强调需要灵活的、量身定制的评估策略和涉及医疗保健专业人员和家庭的协作方法。此外,这表明研究差距较大,需要标准的工具来全面评估盲人失语症患者。本病例报告对评估盲人失语症的有限知识做出了贡献,并呼吁在这一领域进行进一步的研究,以完善和扩展现有的工具和策略。
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引用次数: 0
Diagnostic Study of Mandibular Cortical Index Classification Using Dental Cone-Beam Computed Tomography Findings: A Preliminary Cross-Sectional Study 用牙锥束计算机断层扫描结果诊断下颌骨皮质指数分类的初步横断面研究
Pub Date : 2023-10-11 DOI: 10.3390/reports6040048
Keisuke Seki, Tona Yoshino, Shouhei Ogisawa, Yushi Arai, Morio Tonogi, Toshimitsu Iinuma
The prevalence of osteoporosis is high, reportedly affecting 200 million people worldwide. A major problem associated with osteoporosis is that femoral fractures cause a decline in general function and loss of independence, greatly reducing patients’ quality of life. Notably, osteoporosis is an asymptomatic chronic metabolic disease, and its detection is thus often delayed. Interestingly, mandibular cortical index (MCI) classification using dental panoramic radiography is reportedly useful for early detection of osteoporosis. However, this visual classification method can lead to differences in diagnoses among surgeons. The aim of this preliminary study was to analyze cone-beam computed tomography (CBCT) data and examine an objective MCI classification using the findings obtained. MCI classification (classified as C1, C2, or C3) was performed by three examiners on 70 women (91 sites) aged ≥20 years. The mandibular cortical width of all sites was measured using CBCT images. The results showed that the mandibular cortical width was not particularly correlated with age or number of present teeth, and no significant quantitative differences were found between C1 and C2. However, coronal CBCT images of C2 revealed multiple characteristic trabecular bone structures. These structures may be an important finding affecting the classification of two-dimensional dental panoramic radiography images.
骨质疏松症的患病率很高,据报道全世界有2亿人受到影响。与骨质疏松症相关的一个主要问题是股骨骨折导致一般功能下降和独立性丧失,极大地降低了患者的生活质量。值得注意的是,骨质疏松症是一种无症状的慢性代谢性疾病,因此它的检测经常被延迟。有趣的是,据报道,下颌皮质指数(MCI)分类使用牙科全景x线摄影有助于早期发现骨质疏松症。然而,这种视觉分类方法可能导致外科医生之间的诊断差异。本初步研究的目的是分析锥束计算机断层扫描(CBCT)数据,并根据所获得的结果客观地检查MCI分类。70名年龄≥20岁的女性(91个部位)由3名检查人员进行MCI分类(分为C1、C2或C3)。使用CBCT图像测量下颌骨皮质各部位的宽度。结果表明,下颌骨皮质宽度与年龄、现牙数无明显相关性,C1、C2间无明显定量差异。然而,C2的冠状位CBCT图像显示多个特征性骨小梁结构。这些结构可能是影响二维牙科全景x线摄影图像分类的重要发现。
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引用次数: 0
Facial Nerve Palsy after Inferior Alveolar Nerve Block: A Rare Presentation of Ocular Complication and Literature Review 下肺泡神经阻滞后面神经麻痹:罕见的眼部并发症及文献回顾
Pub Date : 2023-10-04 DOI: 10.3390/reports6040047
Glauco Chisci, Dafne Chisci, Enea Chisci, Viola Chisci, Elettra Chisci
Many ocular complications are described in the literature after dental injections. Facial nerve palsy is a rare complication. We report a case of a 60-year-old woman in the American Society of Anesthesiologists (ASA) I classification under orthodontic treatment with aligners that required an inferior alveolar block for endodontic treatment. Optocaine with epinephrine 1:200,000 and a disposable needle 25 G × 36 mm mounted on a dental syringe were used, and the effect of the anesthesia arose after 10 min. Facial nerve palsy on the side of the injection arose after 1 h and 40 min from the injection, and the patient was immediately visited by an ophthalmologist who reported the examination reported in the present case report. The authors report this unusual case with a subsequent onset and short duration of facial nerve palsy and discuss possible anesthetic solution pathways.
文献中描述了许多牙科注射后的眼部并发症。面神经麻痹是一种罕见的并发症。我们报告一例60岁的妇女在美国麻醉医师协会(ASA) I分类下正畸治疗与对准器需要下牙槽阻滞根管治疗。使用肾上腺素1:20万的光卡因,一次性针头25 G × 36 mm安装在牙科注射器上,麻醉10分钟后出现效果。注射后1小时40分钟后出现注射侧面神经麻痹,患者立即由眼科医生就诊,报告了本病例报告中的检查结果。作者报告了这个不寻常的病例,随后发作和持续时间短的面神经麻痹,并讨论了可能的麻醉溶液途径。
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引用次数: 0
Surgical Treatment of Lung Cancer in Situs Inversus Totalis—A Case Report 肺癌逆行手术治疗1例报告
Pub Date : 2023-09-26 DOI: 10.3390/reports6040046
Janusz Wójcik, Tomasz Grodzki, Jarosław Pieróg, Norbert Wójcik, Dawid Kordykiewicz, Kajetan Kiełbowski, Maja Morozik, Stanisław Brożyna, Paulina Borowik, Małgorzata Edyta Wojtyś
Situs inversus totalis (SIT) is a congenital anomaly that involves the mirror rearrangement of the thoracic and abdominal internal organs. In this paper, we report a 56-year-old male patient with previously confirmed SIT, who was admitted to the hospital for the diagnosis and surgical treatment of non-small-cell lung cancer, located in the sixth right pulmonary segment. The patient underwent segmentectomy with mediastinal and hilar lymphadenectomy. Furthermore, we screened the PubMed and Embase databases for reports of the surgical treatment of patients with SIT and lung cancer. Articles describing inoperable and disseminated disease, as well as patients qualified for palliative treatment, were not included. Ultimately, we compared 21 articles (including the one described here). Data about the clinical condition, tumor characteristics, treatment, and histopathological examination were extracted and summarized.
完全性倒位(SIT)是一种先天性异常,涉及胸腹内脏器官的镜像重排。本文报告一名56岁男性患者,既往确诊为SIT,因右肺第六段非小细胞肺癌而入院接受手术治疗。患者行纵隔淋巴节段切除术及肺门淋巴切除术。此外,我们从PubMed和Embase数据库中筛选了SIT和肺癌患者手术治疗的报告。描述不能手术和播散性疾病的文章以及有资格接受姑息治疗的患者未被纳入。最后,我们比较了21篇文章(包括本文描述的那篇)。对患者的临床情况、肿瘤特征、治疗方法、组织病理学检查等资料进行提取和总结。
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引用次数: 0
Rare Onset of Tubercular Peritonitis Amidst Chronic Renal Dysfunction 慢性肾功能不全时少见的结核性腹膜炎
Pub Date : 2023-09-22 DOI: 10.3390/reports6040044
Romeo Popa, Cristian-Corneliu Georgescu, Daniel-Cosmin Caragea, Daniela Cana-Ruiu, Cristina Ene, Lucretiu Radu, Victor Gheorman, Marius-Ciprian Varut, Veronica Gheorman, Andrei Orezanu, Andrei Razvan Codea, Mirela Ghilusi, Loredana-Adriana Popa, Magdalena Diaconu
Tuberculosis Peritonitis is a serious condition, whose diagnosis is established late due to the nonspecific nature of the clinical features, which delays the performance of imaging investigations and, implicitly, the setting of the diagnosis through biopsy and histopathological examination. We report the case of a 49-year-old man who presented in our clinic with nonspecific symptoms and significant nitrogen retention, with ascites fluid detected during the clinical–paraclinical examination, ultimately confirming the diagnosis of bacillary peritonitis. Confirmation of tuberculous etiology through biopsy and/or bacteriological examination is sovereign for the diagnosis. The therapeutic protocol includes three anti-tuberculostatic drugs, for a period of at least 6 months, with or without the combination of corticosteroid therapy during the first months of treatment. The patient evolution under treatment was initially favorable, but due to peritoneal adhesions, it underwent complications later.
结核性腹膜炎是一种严重的疾病,由于临床特征的非特异性,其诊断建立较晚,从而延迟了影像学检查的进行,并且隐含地延迟了通过活检和组织病理学检查诊断的设置。我们报告一例49岁男性患者,在我们的诊所出现非特异性症状和明显的氮潴留,在临床-临床旁检查中发现腹水,最终确认细菌性腹膜炎的诊断。通过活检和/或细菌学检查确认结核病因是诊断的首要依据。治疗方案包括三种抗结核药物,疗程至少为6个月,在治疗的头几个月联合或不联合使用皮质类固醇治疗。患者在治疗初期进展良好,但由于腹膜粘连,后来出现并发症。
{"title":"Rare Onset of Tubercular Peritonitis Amidst Chronic Renal Dysfunction","authors":"Romeo Popa, Cristian-Corneliu Georgescu, Daniel-Cosmin Caragea, Daniela Cana-Ruiu, Cristina Ene, Lucretiu Radu, Victor Gheorman, Marius-Ciprian Varut, Veronica Gheorman, Andrei Orezanu, Andrei Razvan Codea, Mirela Ghilusi, Loredana-Adriana Popa, Magdalena Diaconu","doi":"10.3390/reports6040044","DOIUrl":"https://doi.org/10.3390/reports6040044","url":null,"abstract":"Tuberculosis Peritonitis is a serious condition, whose diagnosis is established late due to the nonspecific nature of the clinical features, which delays the performance of imaging investigations and, implicitly, the setting of the diagnosis through biopsy and histopathological examination. We report the case of a 49-year-old man who presented in our clinic with nonspecific symptoms and significant nitrogen retention, with ascites fluid detected during the clinical–paraclinical examination, ultimately confirming the diagnosis of bacillary peritonitis. Confirmation of tuberculous etiology through biopsy and/or bacteriological examination is sovereign for the diagnosis. The therapeutic protocol includes three anti-tuberculostatic drugs, for a period of at least 6 months, with or without the combination of corticosteroid therapy during the first months of treatment. The patient evolution under treatment was initially favorable, but due to peritoneal adhesions, it underwent complications later.","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136060670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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