Pub Date : 2023-05-20DOI: 10.25251/skin.7.supp.210
J. Harper, L. Kircik, M. Gold, Adelaide Hebert, J. Sugarman, L. Green, L. Stein Gold, H. Baldwin, J. D. Del Rosso, E. Guenin
{"title":"Early and Sustained Reductions in Moderate-to-Severe Acne With Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel","authors":"J. Harper, L. Kircik, M. Gold, Adelaide Hebert, J. Sugarman, L. Green, L. Stein Gold, H. Baldwin, J. D. Del Rosso, E. Guenin","doi":"10.25251/skin.7.supp.210","DOIUrl":"https://doi.org/10.25251/skin.7.supp.210","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44115570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ewing Sarcoma is the second most common primary bone cancer. To date, only a few cases of primary cutaneous Ewing Sarcoma have been published. We present a unique case of primary cutaneous Ewing Sarcoma, which presented as a blue to violaceous mass on a young woman’s chest. The lesion clinically did not align with previous reports of primary cutaneous Ewing Sarcoma but pathology and immunohistochemical stains confirmed the diagnosis. Because primary cutaneous Ewing Sarcoma may masquerade as benign tumors, dermatologists must be suspicious of otherwise benign looking tumors.
{"title":"A Violaceous Mass of the Chest: An Unsuspected Diagnosis of Primary Ewing Sarcoma","authors":"A. Levin, Armaan Guyara, Leela Athalye","doi":"10.25251/skin.7.3.15","DOIUrl":"https://doi.org/10.25251/skin.7.3.15","url":null,"abstract":"Ewing Sarcoma is the second most common primary bone cancer. To date, only a few cases of primary cutaneous Ewing Sarcoma have been published. We present a unique case of primary cutaneous Ewing Sarcoma, which presented as a blue to violaceous mass on a young woman’s chest. The lesion clinically did not align with previous reports of primary cutaneous Ewing Sarcoma but pathology and immunohistochemical stains confirmed the diagnosis. Because primary cutaneous Ewing Sarcoma may masquerade as benign tumors, dermatologists must be suspicious of otherwise benign looking tumors.","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42607231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Filmmakers use dermatologic findings to help the audiences decipher between ‘good’ and ‘bad’ characters by portraying villains with recognizable skin findings. The objective of this study was to analyze 18 Disney live-action movies in relation to their earlier animated releases to determine whether there were changes or correlation about how the industry portrayed certain characters based on their roles as heroes or villains. Methods: To better understand how the use of dermatological findings are changing in the film industry, eighteen Disney live-action movies in relation to their earlier animated releases were compared for changes or correlation on how the industry portrays certain characters based on their roles as heroes or villains. Results: Film antagonists were depicted with significantly more dermatologic findings than protagonists (p<0.0001). In addition, the frequency of periorbital hyperpigmentation (p=0.02) and nasolabial folds (p=0.05) were significantly higher in antagonists verses protagonists. Conclusion: These findings have important implications about the dermatological content of movies directed toward children. Findings of this study suggest filmmakers are continuing to use common dermatological findings to indirectly portray characters as ‘good’ or ‘bad.’
{"title":"Dermatological Findings in Children’s Films","authors":"Fareen Momin, V. Reese, Richard F. Wagner Jr.","doi":"10.25251/skin.7.3.8","DOIUrl":"https://doi.org/10.25251/skin.7.3.8","url":null,"abstract":"Introduction: Filmmakers use dermatologic findings to help the audiences decipher between ‘good’ and ‘bad’ characters by portraying villains with recognizable skin findings. The objective of this study was to analyze 18 Disney live-action movies in relation to their earlier animated releases to determine whether there were changes or correlation about how the industry portrayed certain characters based on their roles as heroes or villains.\u0000Methods: To better understand how the use of dermatological findings are changing in the film industry, eighteen Disney live-action movies in relation to their earlier animated releases were compared for changes or correlation on how the industry portrays certain characters based on their roles as heroes or villains.\u0000Results: Film antagonists were depicted with significantly more dermatologic findings than protagonists (p<0.0001). In addition, the frequency of periorbital hyperpigmentation (p=0.02) and nasolabial folds (p=0.05) were significantly higher in antagonists verses protagonists.\u0000Conclusion: These findings have important implications about the dermatological content of movies directed toward children. Findings of this study suggest filmmakers are continuing to use common dermatological findings to indirectly portray characters as ‘good’ or ‘bad.’","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43889609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-20DOI: 10.25251/skin.7.supp.215
D. Zakria, S. Morgan-Linnell, N. Brownstone
{"title":"The i31-GEP for sentinel lymph node (SLN) biopsy outperforms the MSKCC nomogram in predicting the risk of having a positive SLN in patients with cutaneous melanoma","authors":"D. Zakria, S. Morgan-Linnell, N. Brownstone","doi":"10.25251/skin.7.supp.215","DOIUrl":"https://doi.org/10.25251/skin.7.supp.215","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43033465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Weir, H. Ahmed, M. Broughton, Lauren C. S. Kole
Introduction Hidradenitis Suppurativa (HS) is a chronic inflammatory disease of the skin highly associated with firsthand smoking. Secondhand smoke, defined as the inhalation of smoke from burning a tobacco product or smoke that is exhaled by smokers, and its relationship to HS has not been assessed. This study aims to determine the prevalence of secondhand smoke exposure in the HS population. Methods In this cross-sectional study (N=136), surveys were both administered in a dermatology clinic and emailed to patients with HS, verruca vulgaris (VV), and atopic dermatitis (AD). Control groups were selected based on secondhand smoke associations: AD has a known association, whereas VV does not. Results The survey response rate was 67.3% (N=136). We found that more than half of HS patients (58.73%) were exposed to secondhand smoke within the last 12 months, whereas 38.30% and 30.77% in the AD and VV groups were exposed, respectively (p=0.0209). Additionally, our data did not identify a significant correlation between secondhand smoke and HS disease severity. Conclusion Our study is the first to assess the prevalence of secondhand smoke exposure in the HS population. However, due to the limitations of the study design and significant differences between study groups, we were unable to assess the true association between HS and secondhand smoke exposure. While our study did not identify an increased prevalence of secondhand smoke exposure in the HS population, it highlights an area for further investigation evaluating the relationship between passive tobacco exposure and inflammatory skin disease.
{"title":"The Prevalence of Secondhand Smoke Exposure in Hidradenitis Suppurativa: A Cross-Sectional Survey Study","authors":"S. Weir, H. Ahmed, M. Broughton, Lauren C. S. Kole","doi":"10.25251/skin.7.3.6","DOIUrl":"https://doi.org/10.25251/skin.7.3.6","url":null,"abstract":"Introduction\u0000Hidradenitis Suppurativa (HS) is a chronic inflammatory disease of the skin highly associated with firsthand smoking. Secondhand smoke, defined as the inhalation of smoke from burning a tobacco product or smoke that is exhaled by smokers, and its relationship to HS has not been assessed. This study aims to determine the prevalence of secondhand smoke exposure in the HS population.\u0000Methods\u0000In this cross-sectional study (N=136), surveys were both administered in a dermatology clinic and emailed to patients with HS, verruca vulgaris (VV), and atopic dermatitis (AD). Control groups were selected based on secondhand smoke associations: AD has a known association, whereas VV does not.\u0000Results\u0000The survey response rate was 67.3% (N=136). We found that more than half of HS patients (58.73%) were exposed to secondhand smoke within the last 12 months, whereas 38.30% and 30.77% in the AD and VV groups were exposed, respectively (p=0.0209). Additionally, our data did not identify a significant correlation between secondhand smoke and HS disease severity.\u0000Conclusion\u0000Our study is the first to assess the prevalence of secondhand smoke exposure in the HS population. However, due to the limitations of the study design and significant differences between study groups, we were unable to assess the true association between HS and secondhand smoke exposure. While our study did not identify an increased prevalence of secondhand smoke exposure in the HS population, it highlights an area for further investigation evaluating the relationship between passive tobacco exposure and inflammatory skin disease.","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42221261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-20DOI: 10.25251/skin.7.supp.217
Leon H Kircik Md, Ryan Hartung PhD, Garrett Campbell, Ewa Hawkins MD PhD
{"title":"Diethylene Glycol Monoethyl Ether Versus Propylene Glycol and Their Impact on Topical Clobetasol Propionate Drug Delivery","authors":"Leon H Kircik Md, Ryan Hartung PhD, Garrett Campbell, Ewa Hawkins MD PhD","doi":"10.25251/skin.7.supp.217","DOIUrl":"https://doi.org/10.25251/skin.7.supp.217","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45490869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-13DOI: 10.25251/skin.7.supp.184
B. King, J. Shapiro, M. Ohyama, A. Egeberg, Y. Dutronc, Yun-Fei Chen, Wen-Shuo Wu, Yu-xin Ding, N. Somani, Rodney D Sinclair
{"title":"Trajectories For Scalp Hair Regrowth In Patients With Severe Alopecia Areata Treated With Baricitinib","authors":"B. King, J. Shapiro, M. Ohyama, A. Egeberg, Y. Dutronc, Yun-Fei Chen, Wen-Shuo Wu, Yu-xin Ding, N. Somani, Rodney D Sinclair","doi":"10.25251/skin.7.supp.184","DOIUrl":"https://doi.org/10.25251/skin.7.supp.184","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42062103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kate Beekman, D. DePalo, J. Grichnik, L. Correa, Jonathan Zager
{"title":"At-Home Microneedling of Acral Skin to Increase Percutaneous Absorption of Imiquimod","authors":"Kate Beekman, D. DePalo, J. Grichnik, L. Correa, Jonathan Zager","doi":"10.25251/skin.7.2.17","DOIUrl":"https://doi.org/10.25251/skin.7.2.17","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42593900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-13DOI: 10.25251/skin.7.supp.151
J. Thyssen, A. Bewley, S. Ständer, Carla Castro, L. Miséry, Brian S. Kim, P. Biswas, G. Chan, D. Myers, Melissa Watkins, J. Alderfer, Erman Güler, J. Silverberg
{"title":"Abrocitinib Reduces Skin Pain in Adolescent and Adult Patients With Moderate-to-Severe Atopic Dermatitis","authors":"J. Thyssen, A. Bewley, S. Ständer, Carla Castro, L. Miséry, Brian S. Kim, P. Biswas, G. Chan, D. Myers, Melissa Watkins, J. Alderfer, Erman Güler, J. Silverberg","doi":"10.25251/skin.7.supp.151","DOIUrl":"https://doi.org/10.25251/skin.7.supp.151","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48598575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-13DOI: 10.25251/skin.7.supp.145
P. Lio, Yestle Kim, S. Balu, A. Guana, D. Bates, D. Mackie, H. Costantino, A. López, J. Soung
{"title":"Real World Baseline Characteristics and Early Patient Reported Outcomes in Adult Patients with Moderate to Severe Atopic Dermatitis Treated with Tralokinumab","authors":"P. Lio, Yestle Kim, S. Balu, A. Guana, D. Bates, D. Mackie, H. Costantino, A. López, J. Soung","doi":"10.25251/skin.7.supp.145","DOIUrl":"https://doi.org/10.25251/skin.7.supp.145","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48733782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}