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Early and Sustained Reductions in Moderate-to-Severe Acne With Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel 固定剂量1.2%克林霉素磷酸酯、3.1%过氧化苯甲酰和0.15%阿达帕林凝胶治疗中重度痤疮的早期和持续疗效
Pub Date : 2023-05-20 DOI: 10.25251/skin.7.supp.210
J. Harper, L. Kircik, M. Gold, Adelaide Hebert, J. Sugarman, L. Green, L. Stein Gold, H. Baldwin, J. D. Del Rosso, E. Guenin
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引用次数: 0
A Violaceous Mass of the Chest: An Unsuspected Diagnosis of Primary Ewing Sarcoma 胸部紫色肿块:原发性尤文氏肉瘤的意外诊断
Pub Date : 2023-05-20 DOI: 10.25251/skin.7.3.15
A. Levin, Armaan Guyara, Leela Athalye
Ewing Sarcoma is the second most common primary bone cancer. To date, only a few cases of primary cutaneous Ewing Sarcoma have been published. We present a unique case of primary cutaneous Ewing Sarcoma, which presented as a blue to violaceous mass on a young woman’s chest. The lesion clinically did not align with previous reports of primary cutaneous Ewing Sarcoma but pathology and immunohistochemical stains confirmed the diagnosis. Because primary cutaneous Ewing Sarcoma may masquerade as benign tumors, dermatologists must be suspicious of otherwise benign looking tumors.
尤文氏肉瘤是第二常见的原发性骨癌。迄今为止,只有少数病例的原发性皮肤尤文氏肉瘤已发表。我们提出一个独特的病例原发性皮肤尤文氏肉瘤,其表现为一个蓝色到紫色肿块在一个年轻的女人的胸部。该病变与先前报道的原发性皮肤尤文氏肉瘤不一致,但病理和免疫组织化学染色证实了诊断。因为原发性皮肤尤文氏肉瘤可能伪装成良性肿瘤,皮肤科医生必须怀疑其他良性肿瘤。
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引用次数: 0
Dermatological Findings in Children’s Films 儿童电影中的皮肤病学发现
Pub Date : 2023-05-20 DOI: 10.25251/skin.7.3.8
Fareen Momin, V. Reese, Richard F. Wagner Jr.
Introduction: Filmmakers use dermatologic findings to help the audiences decipher between ‘good’ and ‘bad’ characters by portraying villains with recognizable skin findings. The objective of this study was to analyze 18 Disney live-action movies in relation to their earlier animated releases to determine whether there were changes or correlation about how the industry portrayed certain characters based on their roles as heroes or villains.Methods: To better understand how the use of dermatological findings are changing in the film industry, eighteen Disney live-action movies in relation to their earlier animated releases were compared for changes or correlation on how the industry portrays certain characters based on their roles as heroes or villains.Results: Film antagonists were depicted with significantly more dermatologic findings than protagonists (p<0.0001). In addition, the frequency of periorbital hyperpigmentation (p=0.02) and nasolabial folds (p=0.05) were significantly higher in antagonists verses protagonists.Conclusion: These findings have important implications about the dermatological content of movies directed toward children. Findings of this study suggest filmmakers are continuing to use common dermatological findings to indirectly portray characters as ‘good’ or ‘bad.’
简介:电影制作人利用皮肤科的发现来帮助观众区分“好”和“坏”角色,通过塑造有可识别皮肤发现的反派角色。本研究的目的是分析18部迪士尼真人电影与其早期动画电影的对比,以确定该行业根据英雄或反派角色对某些角色的刻画是否存在变化或相关性。方法:为了更好地了解皮肤科检查结果在电影行业的使用是如何变化的,将18部迪士尼真人电影与早期动画电影进行了比较,以了解电影行业根据英雄或反派角色塑造某些角色的变化或相关性。结果:膜拮抗剂的皮肤学表现明显多于主角(p<0.0001)。此外,与主角相比,膜拮抗剂眶周色素沉着过度(p=0.02)和鼻唇沟(p=0.05)的频率明显更高。结论:这些发现对儿童电影的皮肤学内容具有重要意义。这项研究的结果表明,电影制作人继续使用常见的皮肤病学发现来间接地将角色描绘成“好”或“坏”
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引用次数: 0
The i31-GEP for sentinel lymph node (SLN) biopsy outperforms the MSKCC nomogram in predicting the risk of having a positive SLN in patients with cutaneous melanoma 在预测皮肤黑色素瘤患者前哨淋巴结(SLN)活检的风险方面,i31-GEP优于MSKCC nomogram
Pub Date : 2023-05-20 DOI: 10.25251/skin.7.supp.215
D. Zakria, S. Morgan-Linnell, N. Brownstone
{"title":"The i31-GEP for sentinel lymph node (SLN) biopsy outperforms the MSKCC nomogram in predicting the risk of having a positive SLN in patients with cutaneous melanoma","authors":"D. Zakria, S. Morgan-Linnell, N. Brownstone","doi":"10.25251/skin.7.supp.215","DOIUrl":"https://doi.org/10.25251/skin.7.supp.215","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43033465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Prevalence of Secondhand Smoke Exposure in Hidradenitis Suppurativa: A Cross-Sectional Survey Study 二手烟暴露在化脓性汗腺炎中的流行:一项横断面调查研究
Pub Date : 2023-05-20 DOI: 10.25251/skin.7.3.6
S. Weir, H. Ahmed, M. Broughton, Lauren C. S. Kole
IntroductionHidradenitis Suppurativa (HS) is a chronic inflammatory disease of the skin highly associated with firsthand smoking. Secondhand smoke, defined as the inhalation of smoke from burning a tobacco product or smoke that is exhaled by smokers, and its relationship to HS has not been assessed. This study aims to determine the prevalence of secondhand smoke exposure in the HS population.MethodsIn this cross-sectional study (N=136), surveys were both administered in a dermatology clinic and emailed to patients with HS, verruca vulgaris (VV), and atopic dermatitis (AD). Control groups were selected based on secondhand smoke associations: AD has a known association, whereas VV does not.ResultsThe survey response rate was 67.3% (N=136). We found that more than half of HS patients (58.73%) were exposed to secondhand smoke within the last 12 months, whereas 38.30% and 30.77% in the AD and VV groups were exposed, respectively (p=0.0209). Additionally, our data did not identify a significant correlation between secondhand smoke and HS disease severity.ConclusionOur study is the first to assess the prevalence of secondhand smoke exposure in the HS population. However, due to the limitations of the study design and significant differences between study groups, we were unable to assess the true association between HS and secondhand smoke exposure. While our study did not identify an increased prevalence of secondhand smoke exposure in the HS population, it highlights an area for further investigation evaluating the relationship between passive tobacco exposure and inflammatory skin disease.
简介:化脓性肢端炎(HS)是一种与直接吸烟密切相关的皮肤慢性炎症性疾病。二手烟,定义为吸入燃烧烟草制品产生的烟雾或吸烟者呼出的烟雾,其与HS的关系尚未得到评估。本研究旨在确定HS人群中二手烟暴露的患病率。方法在这项横断面研究(N=136)中,调查在皮肤科诊所进行,并通过电子邮件发送给HS、寻常疣(VV)和特应性皮炎(AD)患者。对照组是根据二手烟的关联选择的:AD有已知的关联,而VV没有。结果调查有效率为67.3%(N=136)。我们发现,超过一半的HS患者(58.73%)在过去12个月内接触过二手烟,而AD组和VV组分别有38.30%和30.77%接触过二手烟雾(p=0.0209)。此外,我们的数据没有发现二手烟与HS疾病严重程度之间的显著相关性。结论我们的研究首次评估了HS人群中二手烟暴露的患病率。然而,由于研究设计的局限性和研究组之间的显著差异,我们无法评估HS与二手烟暴露之间的真实联系。虽然我们的研究没有发现HS人群中二手烟暴露的患病率增加,但它强调了一个需要进一步调查的领域,即评估被动烟草暴露与炎症性皮肤病之间的关系。
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引用次数: 0
Diethylene Glycol Monoethyl Ether Versus Propylene Glycol and Their Impact on Topical Clobetasol Propionate Drug Delivery 二甘醇单乙醚与丙二醇对丙酸氯倍他索局部给药的影响
Pub Date : 2023-05-20 DOI: 10.25251/skin.7.supp.217
Leon H Kircik Md, Ryan Hartung PhD, Garrett Campbell, Ewa Hawkins MD PhD
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引用次数: 0
Trajectories For Scalp Hair Regrowth In Patients With Severe Alopecia Areata Treated With Baricitinib Baricitinib治疗严重斑秃患者头皮头发再生的轨迹
Pub Date : 2023-03-13 DOI: 10.25251/skin.7.supp.184
B. King, J. Shapiro, M. Ohyama, A. Egeberg, Y. Dutronc, Yun-Fei Chen, Wen-Shuo Wu, Yu-xin Ding, N. Somani, Rodney D Sinclair
{"title":"Trajectories For Scalp Hair Regrowth In Patients With Severe Alopecia Areata Treated With Baricitinib","authors":"B. King, J. Shapiro, M. Ohyama, A. Egeberg, Y. Dutronc, Yun-Fei Chen, Wen-Shuo Wu, Yu-xin Ding, N. Somani, Rodney D Sinclair","doi":"10.25251/skin.7.supp.184","DOIUrl":"https://doi.org/10.25251/skin.7.supp.184","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42062103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
At-Home Microneedling of Acral Skin to Increase Percutaneous Absorption of Imiquimod 在家微针注射肢端皮肤以增加咪喹莫特的经皮吸收
Pub Date : 2023-03-13 DOI: 10.25251/skin.7.2.17
Kate Beekman, D. DePalo, J. Grichnik, L. Correa, Jonathan Zager
{"title":"At-Home Microneedling of Acral Skin to Increase Percutaneous Absorption of Imiquimod","authors":"Kate Beekman, D. DePalo, J. Grichnik, L. Correa, Jonathan Zager","doi":"10.25251/skin.7.2.17","DOIUrl":"https://doi.org/10.25251/skin.7.2.17","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42593900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abrocitinib Reduces Skin Pain in Adolescent and Adult Patients With Moderate-to-Severe Atopic Dermatitis 阿布替尼减轻青少年和成人中重度特应性皮炎患者的皮肤疼痛
Pub Date : 2023-03-13 DOI: 10.25251/skin.7.supp.151
J. Thyssen, A. Bewley, S. Ständer, Carla Castro, L. Miséry, Brian S. Kim, P. Biswas, G. Chan, D. Myers, Melissa Watkins, J. Alderfer, Erman Güler, J. Silverberg
{"title":"Abrocitinib Reduces Skin Pain in Adolescent and Adult Patients With Moderate-to-Severe Atopic Dermatitis","authors":"J. Thyssen, A. Bewley, S. Ständer, Carla Castro, L. Miséry, Brian S. Kim, P. Biswas, G. Chan, D. Myers, Melissa Watkins, J. Alderfer, Erman Güler, J. Silverberg","doi":"10.25251/skin.7.supp.151","DOIUrl":"https://doi.org/10.25251/skin.7.supp.151","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48598575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real World Baseline Characteristics and Early Patient Reported Outcomes in Adult Patients with Moderate to Severe Atopic Dermatitis Treated with Tralokinumab 接受曲洛单抗治疗的中度至重度特应性皮炎成年患者的真实基线特征和早期患者报告的结果
Pub Date : 2023-03-13 DOI: 10.25251/skin.7.supp.145
P. Lio, Yestle Kim, S. Balu, A. Guana, D. Bates, D. Mackie, H. Costantino, A. López, J. Soung
{"title":"Real World Baseline Characteristics and Early Patient Reported Outcomes in Adult Patients with Moderate to Severe Atopic Dermatitis Treated with Tralokinumab","authors":"P. Lio, Yestle Kim, S. Balu, A. Guana, D. Bates, D. Mackie, H. Costantino, A. López, J. Soung","doi":"10.25251/skin.7.supp.145","DOIUrl":"https://doi.org/10.25251/skin.7.supp.145","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48733782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Skin (Milwood, N.Y.)
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