Pub Date : 2024-05-11DOI: 10.1007/s11141-024-10321-y
D. S. Sitnikov, V. A. Revkova, I. V. Ilina, R. O. Shatalova, M. A. Konoplyannikov, V. A. Kalsin, V. P. Baklaushev
We present the results of studying the impact of high-intensity terahertz pulses on the differentiation of induced human neural progenitor cells (drNPCs). The differentiation was estimated using the immunocytochemical analysis, i.e., the marker of the undifferentiated cells (SOX2) and the markers of the neuronal (β-III-tubulin and MAP2b) and glial (GFAP) phenotype. The cell exposure was performed by terahertz pulses with an intensity of 21 GW/cm2 and an electric field of 2.8 MV/cm for 30 min. As a result of exposure, the phenotype of induced neural progenitor cells did not differ from that of unexposed cells and the appearance of mature neurons or glial cells was not detected. The ability of the terahertz radiation to cause effects in neural cell cultures apparently requires further studies for higher exposure intensity or duration.
{"title":"Influence of High-Intensity Terahertz Radiation on the Differentiation of Human Neural Progenitor Cells","authors":"D. S. Sitnikov, V. A. Revkova, I. V. Ilina, R. O. Shatalova, M. A. Konoplyannikov, V. A. Kalsin, V. P. Baklaushev","doi":"10.1007/s11141-024-10321-y","DOIUrl":"10.1007/s11141-024-10321-y","url":null,"abstract":"<p>We present the results of studying the impact of high-intensity terahertz pulses on the differentiation of induced human neural progenitor cells (drNPCs). The differentiation was estimated using the immunocytochemical analysis, i.e., the marker of the undifferentiated cells (SOX2) and the markers of the neuronal (β-III-tubulin and MAP2b) and glial (GFAP) phenotype. The cell exposure was performed by terahertz pulses with an intensity of 21 GW/cm<sup>2</sup> and an electric field of 2.8 MV/cm for 30 min. As a result of exposure, the phenotype of induced neural progenitor cells did not differ from that of unexposed cells and the appearance of mature neurons or glial cells was not detected. The ability of the terahertz radiation to cause effects in neural cell cultures apparently requires further studies for higher exposure intensity or duration.</p>","PeriodicalId":748,"journal":{"name":"Radiophysics and Quantum Electronics","volume":"66 7-8","pages":"618 - 628"},"PeriodicalIF":0.8,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140925597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-11DOI: 10.1007/s11141-024-10315-w
E. M. Novak, A. V. Savilov, S. V. Samsonov
We develop the spatiotemporal theory of a gyrotron backward-wave oscillator (gyro-BWO) which allows broad frequency tuning and is based on the use of a sectioned quasi-optical system with a zigzag path of the signal wave beam. The theory explains the characteristic features of the dependences of the frequency and power of the output signal on the magnitude of the operating magnetic field. We study the competition between various modes of the system during the excitation of the auto-oscillator, predict the possibility of achieving auto-modulation generation regimes (including the regime with a short powerful superradiant pulse formed), and consider the hysteresis effect of frequency characteristics (when the operating magnetic field is varied over an extended generated pulse). Additionally, an external feedback system is proposed as a way to increase the generation efficiency.
{"title":"Sectioned Gyrotron Backward-Wave Oscillator with a Zigzag-Shaped Quasioptical System: Spatiotemporal Theory and Some of Its Results","authors":"E. M. Novak, A. V. Savilov, S. V. Samsonov","doi":"10.1007/s11141-024-10315-w","DOIUrl":"10.1007/s11141-024-10315-w","url":null,"abstract":"<p>We develop the spatiotemporal theory of a gyrotron backward-wave oscillator (gyro-BWO) which allows broad frequency tuning and is based on the use of a sectioned quasi-optical system with a zigzag path of the signal wave beam. The theory explains the characteristic features of the dependences of the frequency and power of the output signal on the magnitude of the operating magnetic field. We study the competition between various modes of the system during the excitation of the auto-oscillator, predict the possibility of achieving auto-modulation generation regimes (including the regime with a short powerful superradiant pulse formed), and consider the hysteresis effect of frequency characteristics (when the operating magnetic field is varied over an extended generated pulse). Additionally, an external feedback system is proposed as a way to increase the generation efficiency.</p>","PeriodicalId":748,"journal":{"name":"Radiophysics and Quantum Electronics","volume":"66 7-8","pages":"548 - 560"},"PeriodicalIF":0.8,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141255432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-11DOI: 10.1007/s11141-024-10310-1
I. A. Ashanin, I. V. Bandurkin, N. Yu. Bylinsky, A. A. Vikharev, K. V. Mineev, N. Yu. Peskov, S. M. Polozov, N. Yu. Samarokov, A. E. Fedotov
We present the results of studies aimed at creation of accelerating structures for a photoinjector accelerator that is currently under construction at the IAP RAS. Based on the general theory of coupled oscillators, a simple method for diagnosing the resonant properties of two-cell accelerating structures is given. Electrodynamic measurements of the manufactured photogun at a low power level confirm the ability to achieve the required acceleration gradient, although they show quite a notable difference between its resonant properties and the design. These measurements are in good agreement with analytical estimates and numerical simulations. The project of an additional accelerating structure designed to further accelerate the photoinjector electron bunches up to the energy providing their efficient injection into a wakefield plasma accelerator is also presented.
{"title":"Design and Testing of the Photogun Resonator and Biperiodic Accelerating Structure with Traveling Wave for the Photoinjector at the IAP RAS","authors":"I. A. Ashanin, I. V. Bandurkin, N. Yu. Bylinsky, A. A. Vikharev, K. V. Mineev, N. Yu. Peskov, S. M. Polozov, N. Yu. Samarokov, A. E. Fedotov","doi":"10.1007/s11141-024-10310-1","DOIUrl":"10.1007/s11141-024-10310-1","url":null,"abstract":"<p>We present the results of studies aimed at creation of accelerating structures for a photoinjector accelerator that is currently under construction at the IAP RAS. Based on the general theory of coupled oscillators, a simple method for diagnosing the resonant properties of two-cell accelerating structures is given. Electrodynamic measurements of the manufactured photogun at a low power level confirm the ability to achieve the required acceleration gradient, although they show quite a notable difference between its resonant properties and the design. These measurements are in good agreement with analytical estimates and numerical simulations. The project of an additional accelerating structure designed to further accelerate the photoinjector electron bunches up to the energy providing their efficient injection into a wakefield plasma accelerator is also presented.</p>","PeriodicalId":748,"journal":{"name":"Radiophysics and Quantum Electronics","volume":"66 7-8","pages":"504 - 512"},"PeriodicalIF":0.8,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140925619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-11DOI: 10.1007/s11141-024-10318-7
E. S. Semenov, M. D. Proyavin, M. V. Morozkin, A. S. Zuev, M. V. Kamensky
The paper is devoted to a comparison of the results of an experimental study of a 28 GHz/25 kW gyrotron with a magnetically shielded system and the results of calculating the electron–wave interaction with the use of the ANGEL software code on the basis of a self-consistent model with an unfixed radio-frequency field structure. The good agreement between the results confirms the validity of using the developed code for creation of new gyrotrons. Comparison of various experimental data with the calculation results for the electron–wave interaction as well as for electron optics makes possible implicit reevaluation of the actual values of some important gyrotron parameters (the electron pitch factor, transverse velocity spread, etc.).
{"title":"Analysis of Generation Regimes in a Technological Gyrotron with a Magnetically Shielded System in the Angel Software Environment","authors":"E. S. Semenov, M. D. Proyavin, M. V. Morozkin, A. S. Zuev, M. V. Kamensky","doi":"10.1007/s11141-024-10318-7","DOIUrl":"10.1007/s11141-024-10318-7","url":null,"abstract":"<p>The paper is devoted to a comparison of the results of an experimental study of a 28 GHz/25 kW gyrotron with a magnetically shielded system and the results of calculating the electron–wave interaction with the use of the ANGEL software code on the basis of a self-consistent model with an unfixed radio-frequency field structure. The good agreement between the results confirms the validity of using the developed code for creation of new gyrotrons. Comparison of various experimental data with the calculation results for the electron–wave interaction as well as for electron optics makes possible implicit reevaluation of the actual values of some important gyrotron parameters (the electron pitch factor, transverse velocity spread, etc.).</p>","PeriodicalId":748,"journal":{"name":"Radiophysics and Quantum Electronics","volume":"66 7-8","pages":"583 - 600"},"PeriodicalIF":0.8,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140925689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1007/s11141-024-10306-x
A. V. Lebedev, S. A. Manakov, D. V. Dubovoy
We consider the problem of Rayleigh wave scattering by an inclusion of small wave sizes in the form of an oblate ellipsoid located under the free surface of an elastic isotropic half-space. The material parameters of the filling of the inclusion can have an arbitrary contrast with respect to the material parameters of the elastic medium containing the inhomogeneity. The solution of the problem is based on the formalism of the Green’s functions of a force source in a half-space and the reciprocity theorem for an elastic medium. The examples demonstrate the possibility of diagnosing the presence of a cavity, as well as estimating its sizes and orientation by analyzing the features of the distribution of the displacement vector projection amplitudes in the scattered field.
{"title":"Rayleigh Wave Scattering by a Near-Surface Inclusion in Elastic Half-Space","authors":"A. V. Lebedev, S. A. Manakov, D. V. Dubovoy","doi":"10.1007/s11141-024-10306-x","DOIUrl":"10.1007/s11141-024-10306-x","url":null,"abstract":"<p>We consider the problem of Rayleigh wave scattering by an inclusion of small wave sizes in the form of an oblate ellipsoid located under the free surface of an elastic isotropic half-space. The material parameters of the filling of the inclusion can have an arbitrary contrast with respect to the material parameters of the elastic medium containing the inhomogeneity. The solution of the problem is based on the formalism of the Green’s functions of a force source in a half-space and the reciprocity theorem for an elastic medium. The examples demonstrate the possibility of diagnosing the presence of a cavity, as well as estimating its sizes and orientation by analyzing the features of the distribution of the displacement vector projection amplitudes in the scattered field.</p>","PeriodicalId":748,"journal":{"name":"Radiophysics and Quantum Electronics","volume":"66 5-6","pages":"441 - 459"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140596720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1007/s11141-024-10307-w
I. V. Kuz’min, S. Yu. Mironov, M. A. Martyanov, A. K. Potemkin
We consider specific features of highly efficient generation of the second (eo-e and oe-o synchronism types) and third (oo-e synchronism type) harmonics using laser pulses with opposite frequency chirps for further application in electron photoinjectors. The relationships of the frequency chirps of the pulses interacting in a nonlinear crystal are obtained for the three-wave frequency summation process, which allow one to ensure high energy efficiency of the conversion and reproduce the spatiotemporal distribution of the intensity of the initial pulses in the generated signal.
{"title":"Features of Generating the Sum-Frequency Radiation Using Laser Pulses with Opposite Frequency Chirps","authors":"I. V. Kuz’min, S. Yu. Mironov, M. A. Martyanov, A. K. Potemkin","doi":"10.1007/s11141-024-10307-w","DOIUrl":"10.1007/s11141-024-10307-w","url":null,"abstract":"<p>We consider specific features of highly efficient generation of the second (eo-e and oe-o synchronism types) and third (oo-e synchronism type) harmonics using laser pulses with opposite frequency chirps for further application in electron photoinjectors. The relationships of the frequency chirps of the pulses interacting in a nonlinear crystal are obtained for the three-wave frequency summation process, which allow one to ensure high energy efficiency of the conversion and reproduce the spatiotemporal distribution of the intensity of the initial pulses in the generated signal.</p>","PeriodicalId":748,"journal":{"name":"Radiophysics and Quantum Electronics","volume":"66 5-6","pages":"460 - 468"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140597228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1007/s11141-024-10308-9
E. A. Khazanov, A. A. Kochetkov, D. E. Silin
We have studied the spectral properties of the inhomogeneities in the surface profile of a quartz plate in the spatial range from 10 μm to 100 mm on the basis of precision interferometric measurements. Analytical integral relations connecting one- and two-dimensional spectral densities of an isotropic random function, such as surface profile or spatial phase distribution of the laser beam, were obtained. It is shown that if the one-dimensional spectral density in a certain range of spatial frequencies decreases in a power-law manner, then the two-dimensional spectral density in the same range also decreases in a power-law manner with an exponent greater by one. The experimental data are in good agreement with the theoretical ones.
我们在精密干涉测量的基础上,研究了石英板表面轮廓在 10 μm 至 100 mm 空间范围内不均匀性的光谱特性。获得了连接各向同性随机函数(如表面轮廓或激光束的空间相位分布)的一维和二维光谱密度的分析积分关系。结果表明,如果空间频率一定范围内的一维光谱密度以幂律方式下降,那么同一范围内的二维光谱密度也会以指数大于 1 的幂律方式下降。实验数据与理论数据十分吻合。
{"title":"Spectral Density of Spatial Noise of a Laser Beam Upon Reflection from a Non-Ideal Surface","authors":"E. A. Khazanov, A. A. Kochetkov, D. E. Silin","doi":"10.1007/s11141-024-10308-9","DOIUrl":"10.1007/s11141-024-10308-9","url":null,"abstract":"<p>We have studied the spectral properties of the inhomogeneities in the surface profile of a quartz plate in the spatial range from 10 μm to 100 mm on the basis of precision interferometric measurements. Analytical integral relations connecting one- and two-dimensional spectral densities of an isotropic random function, such as surface profile or spatial phase distribution of the laser beam, were obtained. It is shown that if the one-dimensional spectral density in a certain range of spatial frequencies decreases in a power-law manner, then the two-dimensional spectral density in the same range also decreases in a power-law manner with an exponent greater by one. The experimental data are in good agreement with the theoretical ones.</p>","PeriodicalId":748,"journal":{"name":"Radiophysics and Quantum Electronics","volume":"66 5-6","pages":"469 - 478"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140596958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1007/s11141-024-10305-y
N. S. Petrukhin, E. N. Pelinovsky, T. G. Talipova
We study the vertical propagation of acoustic waves in a strongly inhomogeneous atmosphere. The class of monotonically varying profiles for the sound velocity, gas density, and gas pressure, for which acoustic waves can propagate with no reflection outside the framework of the classical WKB approximation, is found. This class of solutions, called reflectionless, is obtained by transforming the levels for waves in an ideal gas located in the gravity field into the Euler—Darboux—Poisson equation of a special kind, which has a solution in the form of a superposition of non-interacting waves propagating in opposite directions. It is noted that with this stratification, acoustic waves can have any frequency, in contrast to the exponential atmosphere, where the cutoff frequency is present.
{"title":"Reflectionless Acoustic Waves in an Inhomogeneous Atmosphere","authors":"N. S. Petrukhin, E. N. Pelinovsky, T. G. Talipova","doi":"10.1007/s11141-024-10305-y","DOIUrl":"10.1007/s11141-024-10305-y","url":null,"abstract":"<p>We study the vertical propagation of acoustic waves in a strongly inhomogeneous atmosphere. The class of monotonically varying profiles for the sound velocity, gas density, and gas pressure, for which acoustic waves can propagate with no reflection outside the framework of the classical WKB approximation, is found. This class of solutions, called reflectionless, is obtained by transforming the levels for waves in an ideal gas located in the gravity field into the Euler—Darboux—Poisson equation of a special kind, which has a solution in the form of a superposition of non-interacting waves propagating in opposite directions. It is noted that with this stratification, acoustic waves can have any frequency, in contrast to the exponential atmosphere, where the cutoff frequency is present.</p>","PeriodicalId":748,"journal":{"name":"Radiophysics and Quantum Electronics","volume":"66 5-6","pages":"431 - 440"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140596957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-29DOI: 10.1007/s11141-024-10304-z
L. A. Ostrovsky
We give an outline of selected theoretical and experimental studies associated with the periodaverage action of an oscillating acoustic field (acoustic radiation force) on the medium and microparticles. The main attention is paid to two problems related to biomedical research. One is the generation of shear waves by ultrasonic beams in weakly compressible (rubber-like) media, particularly in soft biological tissues. The other is the dynamics of microparticles in acoustic resonators. Some other aspects of the problem, such as bubble dynamics and acoustic levitation, are briefly mentioned. Elements of the history of early studies are also included.
{"title":"Notes on the Acoustic Radiation Force","authors":"L. A. Ostrovsky","doi":"10.1007/s11141-024-10304-z","DOIUrl":"10.1007/s11141-024-10304-z","url":null,"abstract":"<p>We give an outline of selected theoretical and experimental studies associated with the periodaverage action of an oscillating acoustic field (acoustic radiation force) on the medium and microparticles. The main attention is paid to two problems related to biomedical research. One is the generation of shear waves by ultrasonic beams in weakly compressible (rubber-like) media, particularly in soft biological tissues. The other is the dynamics of microparticles in acoustic resonators. Some other aspects of the problem, such as bubble dynamics and acoustic levitation, are briefly mentioned. Elements of the history of early studies are also included.</p>","PeriodicalId":748,"journal":{"name":"Radiophysics and Quantum Electronics","volume":"66 5-6","pages":"421 - 430"},"PeriodicalIF":0.8,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140325333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-27DOI: 10.1007/s11141-024-10300-3
S. N. Vlasov, E. V. Koposova
We develop the theory of wave-beam diffraction from a reflective grating. The structures are found of the beams that are produced by diffraction of a wave beam from a reflective grating in the regime which is close to the self-collimation one with a high reflection coefficient. The structures of the beams reflected in the backward and mirror directions are presented.
{"title":"Diffraction of Wave Beams from a Reflective Grating","authors":"S. N. Vlasov, E. V. Koposova","doi":"10.1007/s11141-024-10300-3","DOIUrl":"10.1007/s11141-024-10300-3","url":null,"abstract":"<p>We develop the theory of wave-beam diffraction from a reflective grating. The structures are found of the beams that are produced by diffraction of a wave beam from a reflective grating in the regime which is close to the self-collimation one with a high reflection coefficient. The structures of the beams reflected in the backward and mirror directions are presented.</p>","PeriodicalId":748,"journal":{"name":"Radiophysics and Quantum Electronics","volume":"66 5-6","pages":"345 - 356"},"PeriodicalIF":0.8,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140314250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}