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[An Enlarged Perivascular Space: Clinical Relevance and the Role of Imaging in Aging and Neurologic Disorders]. [血管周围空间增大:衰老和神经系统疾病的临床相关性和影像学作用]。
Pub Date : 2022-05-01 Epub Date: 2022-05-25 DOI: 10.3348/jksr.2022.0049
Younghee Yim, Won-Jin Moon

The perivascular space (PVS) of the brain, also known as Virchow-Robin space, consists of cerebrospinal fluid and connective tissues bordered by astrocyte endfeet. The PVS, in a word, is the route over the arterioles, capillaries, and venules where the substances can move. Although the PVS was identified and described first in the literature approximately over 150 years ago, its importance has been highlighted recently after the function of the waste clearing system of the interstitial fluid and wastes was revealed. The PVS is known to be a microscopic structure detected using T2-weighted brain MRI as dot-like hyperintensity lesions when enlarged. Although until recently regarded as normal with no clinical consequence and ignored in many circumstances, several studies have argued the association of an enlarged PVS with neurodegenerative or other diseases. Many questions and unknown facts about this structure still exist; we can only assume that the normal PVS functions are crucial in keeping the brain healthy. In this review, we covered the history, anatomy, pathophysiology, and MRI findings of the PVS; finally, we briefly touched upon the recent trials to better visualize the PVS by providing a glimpse of the brain fluid dynamics and clinical importance of the PVS.

脑的血管周围空间(PVS),也称为Virchow-Robin空间,由脑脊液和结缔组织组成,由星形胶质细胞端足包围。总而言之,PVS是物质通过小动脉、毛细血管和小静脉的通道。尽管PVS在150多年前就被发现并在文献中首次被描述,但其重要性在最近的研究中才得到强调,因为它具有清除组织液和废物的功能。已知PVS是一种显微镜结构,当扩大时,使用t2加权脑MRI检测到点状高强度病变。虽然直到最近才被认为是正常的,没有临床后果,在许多情况下被忽视,但一些研究认为PVS增大与神经退行性或其他疾病有关。关于这个结构的许多问题和未知的事实仍然存在;我们只能假设正常的PVS功能对保持大脑健康至关重要。在这篇综述中,我们涵盖了PVS的历史、解剖、病理生理和MRI表现;最后,我们简要介绍了最近的试验,通过提供脑流体动力学的一瞥和PVS的临床重要性,以更好地可视化PVS。
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引用次数: 1
[Mediastinal Teratoma: A Pictorial Essay]. [纵隔畸胎瘤:图片论文]。
Pub Date : 2022-05-01 Epub Date: 2022-05-25 DOI: 10.3348/jksr.2021.0186
Sang Gyun Kim, Won Gi Jeong, Sang Yun Song, Taebum Lee, Jong Eun Lee, Hye Mi Park, Yun-Hyeon Kim

The mediastinum is the most prevalent site of extragonadal teratomas. Patients with mediastinal mature teratomas are usually young adults, and the condition does not show significant sexual differences. Mediastinal teratomas are mostly located in the anterior mediastinum. Patients are usually asymptomatic, although they can have several complications when the teratomas become large or rupture. Most mediastinal teratomas can be diagnosed using CT. Diagnosing ruptured or malignant teratomas is challenging because of their atypical clinical and radiological presentations. In this article, we describe various manifestations of mediastinal teratomas, with an emphasis on radiologic features.

纵膈是角外畸胎瘤最常见的部位。纵隔成熟畸胎瘤的患者多为青壮年,性别差异不明显。纵隔畸胎瘤多位于前纵隔。患者通常是无症状的,尽管当畸胎瘤变大或破裂时,他们会有一些并发症。大多数纵隔畸胎瘤可通过CT诊断。诊断破裂或恶性畸胎瘤是具有挑战性的,因为他们的临床和放射表现不典型。在这篇文章中,我们描述了纵隔畸胎瘤的各种表现,重点是放射学特征。
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引用次数: 0
Bladder Cancer Metastasis to the Breast in a Male Patient: Imaging Findings on Mammography and Ultrasonography. 1例男性膀胱癌向乳腺转移:乳房x光和超声的影像学表现。
Pub Date : 2022-05-01 Epub Date: 2021-11-04 DOI: 10.3348/jksr.2021.0070
In Na Yoon, Eun Suk Cha, Jeoung Hyun Kim, Jee Eun Lee, Jin Chung

Male breast cancer is rare, accounting for approximately 1% of breast cancers. Metastasis from extra-mammary malignancy to the breast in men is extremely rare. The most common primary tumors that metastasize to the breast in male are prostate, lung, stomach, colorectal cancer, melanoma, and sarcoma. To our knowledge, only a few cases of bladder cancer presenting with metastasis to the male breast have been reported, and metastasis with infiltration rather than mass is extremely rare. We report imaging findings on mammography and ultrasonography in a 59-year-old male with bladder cancer metastatic to the breast.

男性乳腺癌很少见,约占乳腺癌的1%。男性从乳腺外恶性肿瘤转移到乳房是极为罕见的。男性最常见的转移到乳房的原发肿瘤有前列腺癌、肺癌、胃癌、结直肠癌、黑色素瘤和肉瘤。据我们所知,只有少数膀胱癌转移到男性乳房的病例被报道过,而转移以浸润而非肿块的形式出现是极为罕见的。我们报告一位59岁男性膀胱癌转移至乳房的乳房x光检查和超声检查结果。
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引用次数: 1
Transarterial Embolization for Sporadic Renal Angiomyolipoma: Patient Selection and Technical Considerations for Optimal Therapeutic Outcomes. 经动脉栓塞治疗散发性肾血管平滑肌脂肪瘤:患者选择和最佳治疗结果的技术考虑。
Pub Date : 2022-05-01 Epub Date: 2021-12-23 DOI: 10.3348/jksr.2021.0120
Yena Jung, Min Jeong Choi, Bong Man Kim, You Me Kim, Yumi Seo

Although renal angiomyolipoma (AML) is a benign tumor, treatment may be necessary occasionally because it can cause potentially life-threatening retroperitoneal hemorrhage. Transarterial embolization (TAE) is a safe and effective treatment option to prevent the hemorrhagic rupture of AMLs and relieve the symptoms caused by enlarged lesions or active bleeding. However, there is no clear consensus regarding the indications for prophylactic TAE in patients with sporadic renal AMLs. In urgent TAE for bleeding AMLs, there is a likelihood of incomplete embolization when the focus is on stabilizing the clinical symptoms. This pictorial essay discusses the patient selection and technical considerations to achieve optimal therapeutic effects as well as the follow-up findings after TAE.

虽然肾血管平滑肌脂肪瘤(AML)是一种良性肿瘤,但治疗有时是必要的,因为它可能导致潜在的危及生命的腹膜后出血。经动脉栓塞(TAE)是一种安全有效的治疗方法,可防止aml出血性破裂,缓解病变扩大或活动性出血引起的症状。然而,对于散发性肾aml患者预防性TAE的适应症尚无明确的共识。在出血aml的紧急TAE中,当重点是稳定临床症状时,可能存在不完全栓塞的可能性。这篇图片文章讨论了患者的选择和技术考虑,以达到最佳的治疗效果,以及TAE后的随访结果。
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引用次数: 0
Arterio-Biliary Fistula as a Rare Life-Threatening Complication of Transjugular Intrahepatic Portosystemic Shunt: A Case Report. 动脉胆道瘘是经颈静脉肝内门静脉系统分流术中一种罕见的危及生命的并发症:1例报告。
Pub Date : 2022-05-01 Epub Date: 2021-12-11 DOI: 10.3348/jksr.2021.0083
Ji Su Ko, Lyo Min Kwon, Han Myun Kim, Min-Jeong Kim, Hong Il Ha, Ji Won Park, Ji Young Woo

A 46-year-old male with alcoholic liver cirrhosis underwent a transjugular intrahepatic portosystemic shunt (TIPS) for refractory ascites. On the 9th day after the procedure, he presented with melena and decreasing hemoglobin levels. Hemobilia due to fistula formation between the right intrahepatic bile duct and right hepatic artery was suspected on computed tomography. Angiography revealed a fistula of the small branches of the hepatic segmental arteries, and right intrahepatic bile duct was confirmed; embolization was successfully performed with a coil for the eighth segmental hepatic artery, a glue-lipiodol mixture for the fifth segmental hepatic artery, and gelfoam slurry for the right anterior hepatic artery. However, 2 days after embolization, the patient died owing to aggravated disseminated intravascular coagulopathy. When gastrointestinal bleeding occurs after TIPS, careful evaluation is immediately required, and hemobilia should be considered.

一例46岁男性酒精性肝硬化患者因难治性腹水行经颈静脉肝内门体分流术(TIPS)。术后第9天,患者出现黑黑,血红蛋白水平下降。计算机断层扫描怀疑为右肝内胆管与右肝动脉间瘘管形成的胆道出血。血管造影示肝段动脉小支瘘,证实为右肝内胆管;用线圈栓塞第八节段肝动脉,用胶-脂醇混合物栓塞第五节段肝动脉,用明胶泡沫浆栓塞右肝前动脉。然而,栓塞2天后,患者因弥散性血管内凝血病加重而死亡。TIPS术后消化道出血时,应立即仔细评估,并考虑胆道出血。
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引用次数: 0
Clinical Course of Small Subepithelial Tumors of the Small Bowel Detected on CT. CT检查小肠上皮下小肿瘤的临床过程。
Pub Date : 2022-05-01 Epub Date: 2021-12-23 DOI: 10.3348/jksr.2021.0048
Seohyun Kim, Seung Joon Choi, Su Joa Ahn, So Hyun Park, Young Sup Shim, Jeong Ho Kim

Purpose: This study aimed to evaluate the natural growth of subepithelial tumors of the small bowel detected on CT.

Materials and methods: Consecutive patients who were suspected of having subepithelial tumors of the small bowel between January 2005 and December 2020 were reviewed. Eligible patients with suspected small (< 30 mm) subepithelial tumors on at least two CT evaluations were included in the analysis. The patients' data on demographic characteristics, tumoral characteristics, and tumoral size changes during the follow-up were collected.

Results: This study included 64 patients with suspected small subepithelial tumors (n = 64) of the small bowel. After a median follow-up of 15.8 months, the diameter and volume growth rates were 0.02 mm/month and 1.5 mm3/month, respectively. A significant correlation was observed between the initial size and the growth rate of the small bowel subepithelial tumors. The group of large-sized tumors (initial diameter ≥ 10 mm) tended to show lobulated contours, heterogeneous enhancement, and necrotic changes more frequently than the group of small-sized tumors (initial diameter < 10 mm).

Conclusion: Small bowel subepithelial tumors measuring less than 10 mm grew more slowly than those measuring 10-30 mm.

目的:探讨CT检查小肠上皮下肿瘤的自然生长情况。材料和方法:回顾2005年1月至2020年12月期间怀疑患有小肠上皮下肿瘤的连续患者。在至少两次CT评估中疑似小(< 30 mm)上皮下肿瘤的符合条件的患者被纳入分析。收集随访期间患者的人口学特征、肿瘤特征及肿瘤大小变化等资料。结果:本研究纳入64例疑似小肠小上皮下肿瘤的患者(n = 64)。中位随访15.8个月后,直径和体积增长率分别为0.02 mm/月和1.5 mm3/月。小肠上皮下肿瘤的初始大小与生长速度有显著的相关性。大肿瘤(初始直径≥10 mm)组比小肿瘤(初始直径< 10 mm)组更容易出现分叶状轮廓、不均匀强化和坏死改变。结论:小于10 mm的小肠上皮下肿瘤比10 ~ 30 mm的小肠上皮下肿瘤生长缓慢。
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引用次数: 0
[Brain MRI-Based Artificial Intelligence Software in Patients with Neurodegenerative Diseases: Current Status]. [基于脑mri的人工智能软件在神经退行性疾病患者中的应用现状]。
Pub Date : 2022-05-01 DOI: 10.3348/jksr.2022.0048
So Yeong Jeong, Chong Hyun Suh, Ho Young Park, Hwon Heo, Woo Hyun Shim, Sang Joon Kim

The incidence of neurodegenerative diseases in the older population has increased in recent years. A considerable number of studies have been performed to characterize these diseases. Imaging analysis is an important biomarker for the diagnosis of neurodegenerative disease. Objective and reliable assessment and precise detection are important for the early diagnosis of neurodegenerative diseases. Artificial intelligence (AI) using brain MRI applied to the study of neurodegenerative diseases could promote early diagnosis and optimal decisions for treatment plans. MRI-based AI software have been developed and studied worldwide. Representatively, there are MRI-based volumetry and segmentation software. In this review, we present the development process of brain volumetry analysis software in neurodegenerative diseases, currently used and developed AI software for neurodegenerative disease in the Republic of Korea, probable uses of AI in the future, and AI software limitations.

近年来,老年人口中神经退行性疾病的发病率有所增加。已经进行了相当数量的研究来确定这些疾病的特征。影像学分析是诊断神经退行性疾病的重要生物标志物。客观可靠的评估和准确的检测对于神经退行性疾病的早期诊断至关重要。人工智能(AI)将脑MRI应用于神经退行性疾病的研究,可以促进早期诊断和最佳治疗方案的制定。基于核磁共振的人工智能软件已经在世界范围内得到了开发和研究。具有代表性的是基于mri的体积测量和分割软件。在这篇综述中,我们介绍了神经退行性疾病脑容量分析软件的开发过程,韩国目前使用和开发的人工智能软件用于神经退行性疾病,人工智能在未来的可能用途,以及人工智能软件的局限性。
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引用次数: 2
Clinical Efficacy of the Transradial Approach in Percutaneous Intervention for a Malfunctioning Arteriovenous Fistula. 经桡动脉入路经皮介入治疗功能障碍动静脉瘘的临床疗效。
Pub Date : 2022-05-01 Epub Date: 2021-12-11 DOI: 10.3348/jksr.2021.0086
Hyun Young Choi, Gyoo-Sik Jung, Hee Kang, Ye Na Kim, Hyung Hwan Moon, Jong Hyouk Yun

Purpose: To evaluate the effectiveness of the transradial artery approach (TRA) for treating malfunctioning arteriovenous fistulas (AVFs) in patients on hemodialysis.

Materials and methods: A retrospective analysis was conducted in this single-center study of TRA endovascular procedures in 73 patients (43 male and 30 female; mean age of 67.4 years (range, 42-92 years) with malfunctioning AVFs, between January 2008 and April 2019. Patients' baseline and lesion characteristics, technical and clinical success, and complications were evaluated, and functional patency was analyzed using the Kaplan-Meier method.

Results: Radial artery approaches were successful in all patients. Angioplasty performed using the TRA achieved technical and clinical success rates of 98.6%(72/73) and 91.7%(67/73), respectively. The median primary patency time was 18.8 ± 15.9 months. The primary functional patency rates at 3, 6, and 12 months were 82.1%, 68.6%, and 63.9%, respectively. There were no major complications or adverse events, such as hand ischemia, related to the radial artery approach.

Conclusion: In selected cases, the TRA can be used complementary to the transvenous approach to treat malfunctioning AVFs.

目的:探讨经桡动脉入路(TRA)治疗血液透析患者功能障碍动静脉瘘(avf)的疗效。材料和方法:对73例TRA血管内手术的单中心研究进行回顾性分析(男性43例,女性30例;2008年1月至2019年4月期间,平均年龄67.4岁(42-92岁),avf发生故障。评估患者的基线和病变特征、技术和临床成功以及并发症,并使用Kaplan-Meier方法分析功能通畅。结果:所有患者桡动脉入路均成功。使用TRA进行血管成形术的技术和临床成功率分别为98.6%(72/73)和91.7%(67/73)。初次通畅的中位时间为18.8±15.9个月。3个月、6个月和12个月的原发性功能通畅率分别为82.1%、68.6%和63.9%。无桡动脉入路相关的主要并发症或不良事件,如手部缺血。结论:在特定的病例中,TRA可以作为经静脉入路的补充来治疗功能不全的avf。
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引用次数: 1
Feasibility of Pediatric Low-Dose Facial CT Reconstructed with Filtered Back Projection Using Adequate Kernels. 儿童低剂量面部CT滤波后投影重建的可行性。
Pub Date : 2022-05-01 Epub Date: 2021-08-27 DOI: 10.3348/jksr.2021.0003
Hye Ji, Sun Kyoung You, Jeong Eun Lee, So Mi Lee, Hyun-Hae Cho, Joon Young Ohm

Purpose: To evaluate the feasibility of pediatric low-dose facial CT reconstructed with filtered back projection (FBP) using adequate kernels.

Materials and methods: We retrospectively reviewed the clinical and imaging data of children aged < 10 years who underwent facial CT at our emergency department. The patients were divided into two groups: low-dose CT (LDCT; Group A, n = 73) with a fixed 80-kVp tube potential and automatic tube current modulation (ATCM) and standard-dose CT (SDCT; Group B, n = 40) with a fixed 120-kVp tube potential and ATCM. All images were reconstructed with FBP using bone and soft tissue kernels in Group A and only bone kernel in Group B. The groups were compared in terms of image noise, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR). Two radiologists subjectively scored the overall image quality of bony and soft tissue structures. The CT dose index volume and dose-length product were recorded.

Results: Image noise was higher in Group A than in Group B in bone kernel images (p < 0.001). Group A using a soft tissue kernel showed the highest SNR and CNR for all soft tissue structures (all p < 0.001). In the qualitative analysis of bony structures, Group A scores were found to be similar to or higher than Group B scores on comparing bone kernel images. In the qualitative analysis of soft tissue structures, there was no significant difference between Group A using a soft tissue kernel and Group B using a bone kernel with a soft tissue window setting (p > 0.05). Group A showed a 76.9% reduction in radiation dose compared to Group B (3.2 ± 0.2 mGy vs. 13.9 ± 1.5 mGy; p < 0.001).

Conclusion: The addition of a soft tissue kernel image to conventional CT reconstructed with FBP enables the use of pediatric low-dose facial CT protocol while maintaining image quality.

目的:探讨采用滤波后投影法重建儿童低剂量面部CT的可行性。材料和方法:我们回顾性地回顾了在急诊科接受面部CT检查的10岁以下儿童的临床和影像学资料。患者分为两组:低剂量CT (LDCT);A组,n = 73),固定80 kvp管电位和自动管电流调制(ATCM),标准剂量CT (SDCT);B组,n = 40),固定120 kvp管电位和ATCM。A组使用骨核和软组织核重建图像,b组仅使用骨核重建图像,比较各组图像噪声、信噪比(SNR)和噪声对比比(CNR)。两名放射科医生主观地对骨骼和软组织结构的整体图像质量进行评分。记录CT剂量指数、体积和剂量长积。结果:A组骨核图像噪声明显高于B组(p < 0.001)。使用软组织核的A组在所有软组织结构上显示最高的信噪比和CNR(均p < 0.001)。在骨结构的定性分析中,A组评分与B组评分相似或高于B组评分。软组织结构定性分析中,A组软组织核与B组骨核加软组织窗设置无显著差异(p > 0.05)。与B组相比,A组放射剂量降低76.9%(3.2±0.2 mGy vs 13.9±1.5 mGy);P < 0.001)。结论:在FBP重建的常规CT上增加软组织核图像,可以在保持图像质量的同时使用儿童低剂量面部CT方案。
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引用次数: 0
Fibrosing Mediastinits Causing Obstruction of Left Lower Lobar Bronchus: A Pediatric Case Report. 纤维性纵隔引起左下叶支气管梗阻:1例儿科病例报告。
Pub Date : 2022-05-01 Epub Date: 2021-12-11 DOI: 10.3348/jksr.2021.0103
Young Woo Sim, Young Seon Kim, Seung Eun Lee, Min Hye Jang

Fibrosing mediastinitis is a rare benign disorder characterized by the proliferation of dense fibrous tissue within the mediastinum. It typically manifests as localized or infiltrative soft-tissue masses in the middle mediastinum or hilar area, which cause compression and encasement of adjacent mediastinal structures, such as the vessels or airway. Here, we report a rare case of fibrosing mediastinitis in a 13-year-old girl that presented as a middle mediastinal mass lesion on CT scan with obliterating left lower lobar bronchus. The patient's symptoms and follow-up chest CT showed significant improvement following systemic corticosteroid treatment. As fibrosing mediastinitis can improve with systemic steroid therapy, radiologists must be aware of its radiologic findings when discriminating between infiltrating soft tissue lesions in the mediastinum.

纤维性纵隔炎是一种罕见的良性疾病,其特征是纵隔内致密纤维组织的增生。典型表现为中纵隔或肺门区局部或浸润性软组织肿块,压迫和包裹邻近的纵隔结构,如血管或气道。在此,我们报告一个罕见的13岁女孩的纤维化纵隔炎,在CT扫描上表现为中纵隔肿块病变,并伴有左下叶支气管闭塞。患者的症状和随访胸部CT显示全身皮质类固醇治疗后显著改善。由于纤维化性纵隔炎可以通过全身类固醇治疗得到改善,因此放射科医生在区分纵隔浸润性软组织病变时必须了解其影像学表现。
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引用次数: 1
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Taehan Yongsang Uihakhoe chi
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