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[MRI Findings in Parkinson's Disease: Radiologic Assessment of Nigrostriatal Degeneration]. [帕金森病的MRI表现:黑质纹状体变性的影像学评估]。
Pub Date : 2022-05-01 Epub Date: 2022-05-25 DOI: 10.3348/jksr.2022.0044
Yun Jung Bae, Jong-Min Kim, Byung Se Choi, Yoo Sung Song, Yoonho Nam, Se Jin Cho, Jae Hyoung Kim, Sang Eun Kim

Parkinson's disease (PD) is a movement disorder that develops due to degenerative loss of dopaminergic cells in the substantia nigra of the midbrain. Recent advances in MRI techniques have demonstrated various imaging findings that can reflect the underlying pathophysiological processes occurring in Parkinson's disease. Many imaging studies have shown that such findings can assist in the diagnosis of Parkinson's disease and its differentiation from atypical parkinsonism. In this review, we present MRI techniques that can be used in clinical assessment, such as nigrosome imaging and neuromelanin imaging, and we provide the detailed imaging features of Parkinson's disease reflecting nigrostriatal degeneration.

帕金森病(PD)是一种由于中脑黑质多巴胺能细胞退行性丧失而发展的运动障碍。MRI技术的最新进展表明,各种成像结果可以反映帕金森病发生的潜在病理生理过程。许多影像学研究表明,这些发现有助于帕金森病的诊断及其与非典型帕金森病的鉴别。在这篇综述中,我们介绍了可用于临床评估的MRI技术,如黑素体成像和神经黑色素成像,并提供了帕金森病反映黑素体变性的详细成像特征。
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引用次数: 2
Correction: A Bone Metastasis Nude Mouse Model Created by Ultrasound Guided Intracardiac Injection of Breast Cancer Cells: the Micro-CT, MRI and Bioluminescence Imaging Analysis. 校正:超声引导下心脏内注射乳腺癌细胞建立骨转移裸鼠模型:Micro-CT, MRI和生物发光成像分析。
Pub Date : 2022-05-01 Epub Date: 2022-05-25 DOI: 10.3348/jksr.2022.0075
Young Jin Park, Eun Hye Song, Seol Hwa Kim, Sang Hyun Choi, Ho-Taek Song, Jin-Suck Suh

[This corrects the article on p. 57 in vol. 64.].

[这是对第64卷第57页的文章的更正]。
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引用次数: 0
Atypical Ductal Hyperplasia: Risk Factors for Predicting Pathologic Upgrade on Excisional Biopsy. 非典型导管增生:预测切除活检病理升级的危险因素。
Pub Date : 2022-05-01 Epub Date: 2021-10-18 DOI: 10.3348/jksr.2021.0109
Ko Woon Park, Boo-Kyung Han, Sun Jung Rhee, Soo Youn Cho, Eun Young Ko, Eun Sook Ko, Ji Soo Choi

Purpose: To determine the incidence of atypical ductal hyperplasia (ADH) in needle biopsy and the upgrade rate to carcinoma, and to evaluate difference in findings between the upgrade and non-upgrade groups.

Materials and methods: Among 9660 needle biopsies performed over 48 months, we reviewed the radiologic and histopathologic findings of ADH and compared the differences in imaging findings (mammography and breast US) and biopsy methods between the upgrade and non-upgrade groups.

Results: The incidence of ADH was 1.7% (169/9660). Of 112 resected cases and 30 cases followed-up for over 2 years, 35 were upgraded to carcinoma (24.6%, 35/142). The upgrade rates were significantly different according to biopsy methods: US-guided core needle biopsy (US-CNB) (40.7%, 22/54) vs. stereotactic-vacuum-assisted biopsy (S-VAB) (16.0%, 12/75) vs. US-guided VAB (US-VAB) (7.7%, 1/13) (p = 0.002). Multivariable analysis showed that only US-CNB (odds ratio = 5.19, 95% confidence interval: 2.16-13.95, p < 0.001) was an independent predictor for pathologic upgrade. There was no upgrade when a sonographic mass was biopsied by US-VAB (n = 7).

Conclusion: The incidence of ADH was relatively low (1.7%) and the upgrade rate was 24.6%. Surgical excision should be considered because of the considerable upgrade rate, except in the case of US-VAB.

目的:探讨针活检中不典型导管增生(ADH)的发生率及向癌的升级率,评价升级组与非升级组的差异。材料和方法:在48个月内进行的9660例针活检中,我们回顾了ADH的放射学和组织病理学表现,并比较了升级组和非升级组在影像学表现(乳房x线摄影和乳腺超声)和活检方法上的差异。结果:ADH的发生率为1.7%(169/9660)。112例切除,30例随访2年以上,35例升级为恶性肿瘤(24.6%,35/142)。不同活检方法的升级率有显著差异:US-guided core needle biopsy (US-CNB) (40.7%, 22/54) vs. stereo定向真空辅助活检(S-VAB) (16.0%, 12/75) vs. US-guided VAB (US-VAB) (7.7%, 1/13) (p = 0.002)。多变量分析显示,只有US-CNB(优势比为5.19,95%可信区间为2.16-13.95,p < 0.001)是病理升级的独立预测因子。超声肿块行US-VAB活检无升级(n = 7)。结论:ADH发生率较低(1.7%),升级率为24.6%。除US-VAB外,由于升级率较高,应考虑手术切除。
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引用次数: 0
Uterine Artery Embolization as an Effective Management and Diagnostic Tool for Puerperal Uterine Inversion with Severe Postpartum Bleeding: A Case Report. 子宫动脉栓塞术作为产后重度子宫内翻出血的有效治疗和诊断工具1例。
Pub Date : 2022-05-01 Epub Date: 2021-12-11 DOI: 10.3348/jksr.2021.0062
Seong Ju Kim, Youngjong Cho, Sung-Joon Park, Sangjoon Lee, Hyoung Nam Lee, Da Hye Ju

Acute puerperal uterine inversion is a rare postpartum obstetric complication; however, without rapid diagnosis and appropriate management, it is life-threatening. Substantial bleeding hinders the verification of a partially inverted uterus, possibly delaying the treatment. Herein, we present the report of a 32-year-old female presenting with massive postpartum bleeding managed by uterine artery embolization. The peculiar course of the uterine artery bowing inferiorly along the inverted fundus during embolization could uncover the uterine inversion, which was not diagnosed by physical examination and CT. In conclusion, uterine artery embolization is not only an effective therapeutic strategy for postpartum hemorrhage but also a valuable tool for diagnosing uterine inversion.

急性产后子宫内翻是一种罕见的产后产科并发症;然而,如果没有快速诊断和适当的管理,它是危及生命的。大量出血阻碍了部分子宫内翻的确认,可能会延迟治疗。在此,我们报告了一名32岁的女性,通过子宫动脉栓塞治疗产后大出血。栓塞时子宫动脉沿眼底内翻向下弯曲的特殊路线可发现子宫内翻,但未通过体格检查和CT诊断。总之,子宫动脉栓塞不仅是产后出血的有效治疗策略,也是子宫内翻诊断的重要工具。
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引用次数: 0
Incidentally Diagnosed Duodenal Web in Infancy. 婴儿期偶然诊断十二指肠网。
Pub Date : 2022-05-01 DOI: 10.3348/jksr.2021.0047
Suh Young Kim, Byoung Hee Han, Ki Young Park, Jung-Man Namgoong, Da Hee Woo

A duodenal web is an incomplete diaphragm of the duodenal lumen that causes a partial or (intermittent) complete obstruction. The size of a duodenal web's aperture determines the degree of obstruction, age at presentation, and radiologic findings. We report a case of duodenal web incidentally diagnosed in a 14-month-old boy who presented to the hospital after ingesting a foreign body. We provide a comprehensive report of multiple studies through abdominal radiograph, upper gastrointestinal study, endoscopy, and surgical findings. We emphasize that the duodenum should be considered as the location of the obstruction when infants exhibit delayed discharge or dynamic positioning of a foreign body in a radiologic examination.

十二指肠网是十二指肠管腔的不完整隔膜,引起部分或(间歇性)完全阻塞。十二指肠网孔径的大小决定了梗阻程度、发病年龄和影像学表现。我们报告一个病例十二指肠网偶然诊断在一个14个月大的男孩谁提出了医院后,摄取异物。我们通过腹部x线片,上消化道检查,内窥镜检查和手术结果提供了多项研究的综合报告。我们强调,当婴儿在放射检查中表现出延迟排出或异物动态定位时,应将十二指肠视为梗阻的位置。
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引用次数: 0
Pseudomembranous Aspergillus Tracheobronchitis: Case Report of a Rare Manifestation of Airway Invasive Aspergillosis. 假膜性曲霉气管支气管炎:气管侵袭性曲霉菌病罕见表现的病例报告。
Pub Date : 2022-05-01 Epub Date: 2021-11-04 DOI: 10.3348/jksr.2021.0091
Jae Sung Cho, Jeong Jae Kim, Sun Young Jeong, Yun Soo Lee, Miok Kim, Sung Joon Park, Myeong Ju Koh

Aspergillus tracheobronchitis, an uncommon form of invasive pulmonary aspergillosis, is characterized by the development of a pseudomembrane, ulcers, or an obstruction that is predominantly confined to the tracheobronchial tree. Pseudomembranous Aspergillus tracheobronchitis is the most severe form of Aspergillus tracheobronchitis, and only a few cases have been reported in Korea. We report the characteristic chest CT findings in a patient diagnosed with pseudomembranous Aspergillus tracheobronchitis after bronchoscopy and successfully treated by proper antifungal treatment.

曲霉菌气管支气管炎是一种不常见的侵袭性肺曲霉菌病,其特点是出现假膜、溃疡或主要局限于气管支气管树的阻塞。假膜性曲霉菌气管支气管炎是曲霉菌气管支气管炎中最严重的一种,在韩国仅有少数病例报道。我们报告了一名患者在支气管镜检查后被诊断为假膜曲霉菌性气管支气管炎,并通过适当的抗真菌治疗成功治愈的特征性胸部 CT 结果。
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引用次数: 0
[Brain Iron Imaging in Aging and Cognitive Disorders: MRI Approaches]. [衰老和认知障碍中的脑铁成像:核磁共振成像方法]。
Pub Date : 2022-05-01 Epub Date: 2022-05-25 DOI: 10.3348/jksr.2022.0038
Jinhee Jang, Junghwa Kang, Yoonho Nam

Iron has a vital role in the human body, including the central nervous system. Increased deposition of iron in the brain has been reported in aging and important neurodegenerative diseases. Owing to the unique magnetic resonance properties of iron, MRI has great potential for in vivo assessment of iron deposition, distribution, and non-invasive quantification. In this paper, we will review the MRI methods for iron assessment and their changes in aging and neurodegenerative diseases, focusing on Alzheimer's disease. In addition, we will summarize the limitations of current approaches and introduce new areas and MRI methods for iron imaging that are expected in the future.

铁在人体(包括中枢神经系统)中发挥着至关重要的作用。据报道,在衰老和重要的神经退行性疾病中,大脑中铁的沉积会增加。由于铁具有独特的磁共振特性,磁共振成像在体内评估铁的沉积、分布和无创量化方面具有巨大潜力。在本文中,我们将回顾用于铁评估的磁共振成像方法及其在衰老和神经退行性疾病中的变化,重点是阿尔茨海默病。此外,我们还将总结当前方法的局限性,并介绍未来有望出现的铁成像新领域和磁共振成像方法。
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引用次数: 0
[Recent Updates on PET Imaging in Neurodegenerative Diseases]. [神经退行性疾病PET成像的最新进展]。
Pub Date : 2022-05-01 Epub Date: 2022-05-25 DOI: 10.3348/jksr.2022.0052
Yu Kyeong Kim

Over the past decades, the immense clinical need for early detection methods and treatments for dementia has become a priority worldwide. The advances in PET biomarkers play increasingly important roles in understanding disease mechanisms by demonstrating the protein pathology underlying dementia in the brain. Amyloid-β and tau deposition in PET images are now key diagnostic biomarkers for the Alzheimer's disease continuum. The inclusion of biomarkers in the diagnostic criteria has achieved a paradigm shift in facilitating early differential diagnosis, predicting disease prognosis, and influencing clinical management. Furthermore, in vivo images showing pathology could become prognostic as well as surrogate biomarkers in therapeutic trials. In this review, we focus on recent developments in radiotracers for amyloid-β and tau PET imaging in Alzheimer's disease and other neurodegenerative diseases. Further, we introduce their potential application as future perspectives.

在过去的几十年里,对痴呆症早期检测方法和治疗的巨大临床需求已成为世界范围内的优先事项。PET生物标记物的进展在通过揭示大脑中痴呆的蛋白质病理机制来理解疾病机制方面发挥着越来越重要的作用。PET图像中的淀粉样蛋白-β和tau沉积现在是阿尔茨海默病连续体的关键诊断生物标志物。将生物标志物纳入诊断标准在促进早期鉴别诊断、预测疾病预后和影响临床管理方面实现了范式转变。此外,显示病理的体内图像可以成为治疗试验中的预后和替代生物标志物。在这篇综述中,我们重点介绍了淀粉样蛋白-β和tau PET成像在阿尔茨海默病和其他神经退行性疾病中的放射性示踪剂的最新进展。进一步介绍了它们的应用前景。
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引用次数: 0
Florid Reactive Periostitis of the Clavicle: A Case Report. 锁骨鲜红反应性骨膜炎1例。
Pub Date : 2022-03-01 Epub Date: 2022-01-26 DOI: 10.3348/jksr.2021.0108
Hye Eun Park, Jee Won Chai, Chris Hyunchul Jo, Ji Eun Kim, Dong Hyun Kim, Hyo Jin Kim, Jiwoon Seo

Florid reactive periostitis (FRP) is a rare benign fibro-osseous proliferation, occurring mostly in the short tubular bones of hands and rarely in the long tubular bones. We report a surgically confirmed case of FRP involving the clavicle in a 26-year-old male. On MRI scans, a soft tissue mass with T2 high signal intensity was found that originated from the periosteum of the clavicle and included surrounding a periosteal elevation and perilesional soft tissue edema. Strong contrast enhancement was noted inside the mass and along the periosteum involving more than half of the circumference of the clavicle. Serial radiographs revealed a soft tissue mass without mineralization that turned into an ossified mass with a solid periosteal reaction within a month.

鲜红反应性骨膜炎(FRP)是一种罕见的良性纤维骨增生,主要发生在手的短管骨,很少发生在长管骨。我们报告一例涉及锁骨的手术确诊玻璃钢病例,患者为26岁男性。MRI扫描发现一软组织肿块,T2高信号强度,起源于锁骨骨膜,包括周围骨膜抬高和病灶周围软组织水肿。肿块内部及骨膜强对比增强,超过锁骨周长的一半。一系列x线片显示一个没有矿化的软组织肿块,在一个月内变成了骨化肿块,伴有实心骨膜反应。
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引用次数: 0
Malignant Tenosynovial Giant Cell Tumor Presenting as an Extra-Articular Superficial Soft-Tissue Mass in a Knee. 恶性腱鞘巨细胞瘤表现为膝关节关节外浅表软组织肿块。
Pub Date : 2022-03-01 Epub Date: 2022-03-28 DOI: 10.3348/jksr.2021.0065
Jimin Lee, In Sook Lee, You Seon Song, Jeung Il Kim, Kyung Un Choi

Malignant tenosynovial giant cell tumor (TsGCT) is a rare disease that can arise as a recurrent lesion or co-exist with a benign TsGCT lesion. Here we report a rare case of malignant TsGCT in a 73-year-old male with a history of lymphoma. The tumor appeared as a superficial soft-tissue mass in the subcutaneous fat tissue of the left knee.

恶性腱鞘巨细胞瘤(TsGCT)是一种罕见的疾病,可以复发或与良性TsGCT病变共存。我们在此报告一例罕见的恶性TsGCT,患者为73岁男性,既往有淋巴瘤病史。肿瘤表现为左膝皮下脂肪组织的浅表软组织肿块。
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引用次数: 0
期刊
Taehan Yongsang Uihakhoe chi
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