Pub Date : 2019-01-01DOI: 10.18772/26180197.2019.v1n3a2
J. Fabian, J. Loveland, H. Maher, P. Gaylard, H. Etheredge, C. Bouter, J. Cantrell, C. Sanyika, R. Britz, B. Strobele, S. Rambarran, F van der Schyff, L. Brannigan, D. Demopoulos, A. Lang, L. Archibald-Durham, M. Beretta, B. Bobat, A. G. Mahomed, A. Terblanche, J. Botha
{"title":"Wits Transplant Annual Data Report 2018 Adult and Paediatric Liver Transplantation","authors":"J. Fabian, J. Loveland, H. Maher, P. Gaylard, H. Etheredge, C. Bouter, J. Cantrell, C. Sanyika, R. Britz, B. Strobele, S. Rambarran, F van der Schyff, L. Brannigan, D. Demopoulos, A. Lang, L. Archibald-Durham, M. Beretta, B. Bobat, A. G. Mahomed, A. Terblanche, J. Botha","doi":"10.18772/26180197.2019.v1n3a2","DOIUrl":"https://doi.org/10.18772/26180197.2019.v1n3a2","url":null,"abstract":"","PeriodicalId":75326,"journal":{"name":"Wits journal of clinical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83574096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.18772/26180197.2019.v1n1a5
Mohammed Variava, M. Mashabane, A. Bentley, S. Naicker
Background: Acute kidney injury (AKI) occurs commonly within the hospital setting and is associated with a high rate of morbidity and mortality. Factors such as social, economic and ethical dilemmas are closely associated with initiation of dialysis in the public health sector. Methods: A retrospective review of 324 patients presenting with kidney failure who were initiated on acute dialysis at the Chris Hani Baragwanath Hospital was carried out over a 2-year period from July 2009 to June 2011. Results: The mean age at presentation was 40 ± 13 years; 57% of patients were male and 92% were Black. HIV positivity occurred in 26% of patients. The leading indications for acute dialysis included decompensated chronic kidney disease (38.9%), acute tubular necrosis (ATN) (38.3%), HIV-related kidney disease (13.6%), malaria (5.7%), pregnancy-related kidney disease (7.4%) and glomerulonephritis (7.4%). ATN was the predominant cause of AKI in HIV-positive patients. The overall renal recovery rate was 31%, and the overall mortality rate was 23%. About 44.6% of patients had chronic consequences, with 23% being transferred to chronic renal replacement therapy (RRT) and 21.6% transferred to renal outpatients (ROPD) with cessation of dialysis; 1.4% were lost to follow-up. While HIV-positive patients had a better renal recovery rate compared to HIV-negative patients (36% versus 26%; p < 0.0001), they had a higher mortality rate compared to their HIV-negative counterparts (34% versus 19%; p < 0.0001). Conclusion: AKI remains a common presentation that often requires dialysis, a precious resource in an already overburdened health system, and occurs at similar rates in HIV-positive and HIV-negative patients. The underlying aetiology of AKI at Chris Hani Baragwanath resembles that of other developing countries with ATN, malaria, sepsis and pregnancy-induced kidney injury amongst the leading causes. High mortality rates were observed in patients with ATN, in both HIV-positive and HIV-negative patients.
{"title":"Epidemiology and Outcomes of Dialysis-Requiring Acute Kidney Injury at Chris Hani Baragwanath Hospital","authors":"Mohammed Variava, M. Mashabane, A. Bentley, S. Naicker","doi":"10.18772/26180197.2019.v1n1a5","DOIUrl":"https://doi.org/10.18772/26180197.2019.v1n1a5","url":null,"abstract":"Background: Acute kidney injury (AKI) occurs commonly within the hospital setting and is associated with a high rate of morbidity and mortality. Factors such as social, economic and ethical dilemmas are closely associated with initiation of dialysis in the public health sector. Methods: A retrospective review of 324 patients presenting with kidney failure who were initiated on acute dialysis at the Chris Hani Baragwanath Hospital was carried out over a 2-year period from July 2009 to June 2011. Results: The mean age at presentation was 40 ± 13 years; 57% of patients were male and 92% were Black. HIV positivity occurred in 26% of patients. The leading indications for acute dialysis included decompensated chronic kidney disease (38.9%), acute tubular necrosis (ATN) (38.3%), HIV-related kidney disease (13.6%), malaria (5.7%), pregnancy-related kidney disease (7.4%) and glomerulonephritis (7.4%). ATN was the predominant cause of AKI in HIV-positive patients. The overall renal recovery rate was 31%, and the overall mortality rate was 23%. About 44.6% of patients had chronic consequences, with 23% being transferred to chronic renal replacement therapy (RRT) and 21.6% transferred to renal outpatients (ROPD) with cessation of dialysis; 1.4% were lost to follow-up. While HIV-positive patients had a better renal recovery rate compared to HIV-negative patients (36% versus 26%; p < 0.0001), they had a higher mortality rate compared to their HIV-negative counterparts (34% versus 19%; p < 0.0001). Conclusion: AKI remains a common presentation that often requires dialysis, a precious resource in an already overburdened health system, and occurs at similar rates in HIV-positive and HIV-negative patients. The underlying aetiology of AKI at Chris Hani Baragwanath resembles that of other developing countries with ATN, malaria, sepsis and pregnancy-induced kidney injury amongst the leading causes. High mortality rates were observed in patients with ATN, in both HIV-positive and HIV-negative patients.","PeriodicalId":75326,"journal":{"name":"Wits journal of clinical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83613317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.18772/26180197.2019.v1n3a6
{"title":"Abstracts of Oral Presentations by Session","authors":"","doi":"10.18772/26180197.2019.v1n3a6","DOIUrl":"https://doi.org/10.18772/26180197.2019.v1n3a6","url":null,"abstract":"","PeriodicalId":75326,"journal":{"name":"Wits journal of clinical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80206184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.18772/26180197.2019.v1n2a6
D. Reddy, R. Wadee, J. Hasselt, A. Adam
{"title":"The ‘Angry’ Scrotum: Idiopathic Scrotal Calcinosis: A Case Report","authors":"D. Reddy, R. Wadee, J. Hasselt, A. Adam","doi":"10.18772/26180197.2019.v1n2a6","DOIUrl":"https://doi.org/10.18772/26180197.2019.v1n2a6","url":null,"abstract":"","PeriodicalId":75326,"journal":{"name":"Wits journal of clinical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79040125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.18772/26180197.2019.v1n1a02
{"title":"Re: Wits School of Clinical Medicine Journal","authors":"","doi":"10.18772/26180197.2019.v1n1a02","DOIUrl":"https://doi.org/10.18772/26180197.2019.v1n1a02","url":null,"abstract":"","PeriodicalId":75326,"journal":{"name":"Wits journal of clinical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82407508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.18772/26180197.2022.v4n3a11
L. Manderson, Susan Levine
{"title":"Climate Change and a plea for Social Justice in South Africa","authors":"L. Manderson, Susan Levine","doi":"10.18772/26180197.2022.v4n3a11","DOIUrl":"https://doi.org/10.18772/26180197.2022.v4n3a11","url":null,"abstract":"","PeriodicalId":75326,"journal":{"name":"Wits journal of clinical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78346242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.18772/26180197.2023.v5n2a1
Abraham Anu, Greenstein Lara Sonia, Kalla Ismail
On a global scale, the population aged 65 and over is the fastest growing age group. By the year 2050, one in six people will be aged over 65 years, compared to only one in eleven during 2019. The adverse effects of climate change have a broad range of negative impacts on human health and psychosocial status. For the vulnerable ageing population, often limited by their physical, cognitive, psychosocial conditions and economic resources, the effects of climate change can be exceptionally challenging. Compounded by pre-existing medical conditions, immunosenescence, and the presence of various geriatric syndromes, the older persons find themselves at risk of disease exacerbation when exposed to climate-related stressors compared to younger adults. This review is aimed at exploring various aspects of climate change and its impact on older persons’ health.
{"title":"Effect of Climate Change on Health in Older Persons","authors":"Abraham Anu, Greenstein Lara Sonia, Kalla Ismail","doi":"10.18772/26180197.2023.v5n2a1","DOIUrl":"https://doi.org/10.18772/26180197.2023.v5n2a1","url":null,"abstract":"\u0000On a global scale, the population aged 65 and over is the fastest growing age group. By the year 2050, one in six people will be aged over 65 years, compared to only one in eleven during 2019. The adverse effects of climate change have a broad range of negative impacts on human health and psychosocial status. For the vulnerable ageing population, often limited by their physical, cognitive, psychosocial conditions and economic resources, the effects of climate change can be exceptionally challenging. Compounded by pre-existing medical conditions, immunosenescence, and the presence of various geriatric syndromes, the older persons find themselves at risk of disease exacerbation when exposed to climate-related stressors compared to younger adults. This review is aimed at exploring various aspects of climate change and its impact on older persons’ health.","PeriodicalId":75326,"journal":{"name":"Wits journal of clinical medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80072917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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