The clinical and detailed angiographical findings taken during the follow-up of 182 patients with tumors of the iris and the ciliary body reported. On the basis of different angiographic staining patterns, these tumors were divided into three groups. Group I: Clinically, as a rule darkly pigmented, slightly or nonprominent tumors, which do not take up fluorescein at all, i.e. no staining of the tumor of its surroundings during the whole angiogram. 107 patients with such a tumor type did not show any clinical or angiographical changes during several years of follow-up. Those tumors which were excised (4) proved to be nevi. We therefore believe this fluorescein pattern indicates a benign lesion so that examination every 6 months suffice. Group II: These are usually less pigmented and only slightly prominent and have their own vascular network. On fluorescein angiography there is dye leakage within the tumor and into the surrounding iris stroma as well as into the aqueous humor. Of a total of 52 cases 9 were excised via iridectomy or iridocyclectomy. Of these 5 were shown to be benign nevi, 4 however were diagnosed as malignant melanomas. We therefore classify this fluorescein angiographical pattern as belonging to potentially malignant tumors, needing frequent controls, i.e. at 3-month intervals. Group III: Clinically these tumors are usually darkly pigmented, extremely prominent and mostly situated in the peripheral iris, originating here or spreading forward from the ciliary body. They are usually vascularized and show - if the melanin content is not too dense - early mottled staining in the vicinity of the tumor. They furthermore always have a marginal central borderline fluorescence as a typical sign, often accompanied by dye leakage from normal iris vessels, representing so-called 'tumor iritis'. 18 tumors of this type were excised via iridocyclectomy or enucleation and all were shown to be malignant melanomas of the iris or the ciliary body on histopathological examination. This fluorescence pattern group of tumors should always be regarded as definitely malignant, and therefore need prompt surgical excision.
{"title":"Fluorescence angiographical studies in the diagnosis and follow-up of tumors of the iris and ciliary body.","authors":"U Demeler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The clinical and detailed angiographical findings taken during the follow-up of 182 patients with tumors of the iris and the ciliary body reported. On the basis of different angiographic staining patterns, these tumors were divided into three groups. Group I: Clinically, as a rule darkly pigmented, slightly or nonprominent tumors, which do not take up fluorescein at all, i.e. no staining of the tumor of its surroundings during the whole angiogram. 107 patients with such a tumor type did not show any clinical or angiographical changes during several years of follow-up. Those tumors which were excised (4) proved to be nevi. We therefore believe this fluorescein pattern indicates a benign lesion so that examination every 6 months suffice. Group II: These are usually less pigmented and only slightly prominent and have their own vascular network. On fluorescein angiography there is dye leakage within the tumor and into the surrounding iris stroma as well as into the aqueous humor. Of a total of 52 cases 9 were excised via iridectomy or iridocyclectomy. Of these 5 were shown to be benign nevi, 4 however were diagnosed as malignant melanomas. We therefore classify this fluorescein angiographical pattern as belonging to potentially malignant tumors, needing frequent controls, i.e. at 3-month intervals. Group III: Clinically these tumors are usually darkly pigmented, extremely prominent and mostly situated in the peripheral iris, originating here or spreading forward from the ciliary body. They are usually vascularized and show - if the melanin content is not too dense - early mottled staining in the vicinity of the tumor. They furthermore always have a marginal central borderline fluorescence as a typical sign, often accompanied by dye leakage from normal iris vessels, representing so-called 'tumor iritis'. 18 tumors of this type were excised via iridocyclectomy or enucleation and all were shown to be malignant melanomas of the iris or the ciliary body on histopathological examination. This fluorescence pattern group of tumors should always be regarded as definitely malignant, and therefore need prompt surgical excision.</p>","PeriodicalId":75447,"journal":{"name":"Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18238676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Tissue effects of argon laser photocoagulation at threshold doses. Experimental study on the retina of the miniature pig and the rabbit].","authors":"J M Schepens, U Englert, P M Leuenberger","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75447,"journal":{"name":"Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18062379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The anterior-chamber intraocular lens. Geometrical optics of Binkhorst's anterior-chamber lens and its practical consequences].","authors":"E Bürki","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75447,"journal":{"name":"Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18238677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Congenital glaucoma. Clinical, therapeutic and histological aspects].","authors":"S Lalive d'Epinay","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75447,"journal":{"name":"Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18446341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recommended stardard procedures for the clinical measurement and specification of visual acuity. Report of working group 39. Committee on vision. Assembly of Behavioral and Social Sciences, National Research Council, National Academy of Sciences, Washington, D.C.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75447,"journal":{"name":"Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18050823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Anesthesiologic aspects of intraocular intervention, with regard to intraocular lens implantation].","authors":"E Schleussner, G Hempelmann","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75447,"journal":{"name":"Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18050824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This article summarizes the proceedings of a workshop which explored new ideas and technology in optics and psychophysics which might be directed toward the diagnosis of retinal diseases and abnormalities of the visual nervous system. The workshop attempted to initiate an interaction between laboratory scientists and clinicians that would allow them to evaluate which techniques in psychophysics and physiological optics were ready for clinical exploration. Workshop participants examined four broad clinical areas toward which this technology might be directed: (1) localization of anomalies in disorders of the retina; (2) evaluation of patients with common eye diseases; (3) prevention of visual disorders and optimization of visual functions, and (4) acquisition of normative data. Whithin these four broad areas, a number of specific diagnostic applications of psychophysical and optical measurement methods were discussed. Participants also discussed mechanisms by which the National Eye Institute might coordinate laboratory and clinical research in this field.
{"title":"Workshop on the role of psychophysics and physiological optics in ophthalmic diagnosis and patient evaluation. Bethesda, Md, September 19--20, 1976.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This article summarizes the proceedings of a workshop which explored new ideas and technology in optics and psychophysics which might be directed toward the diagnosis of retinal diseases and abnormalities of the visual nervous system. The workshop attempted to initiate an interaction between laboratory scientists and clinicians that would allow them to evaluate which techniques in psychophysics and physiological optics were ready for clinical exploration. Workshop participants examined four broad clinical areas toward which this technology might be directed: (1) localization of anomalies in disorders of the retina; (2) evaluation of patients with common eye diseases; (3) prevention of visual disorders and optimization of visual functions, and (4) acquisition of normative data. Whithin these four broad areas, a number of specific diagnostic applications of psychophysical and optical measurement methods were discussed. Participants also discussed mechanisms by which the National Eye Institute might coordinate laboratory and clinical research in this field.</p>","PeriodicalId":75447,"journal":{"name":"Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18446342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proteins in aqueous humor.","authors":"M Zirm","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75447,"journal":{"name":"Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18372897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The reported demography and causes of blindness throughout the world.","authors":"H Goldstein","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75447,"journal":{"name":"Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17219970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First interprofessional standard for visual field testing. Report of working group 39. Committee on Vision Assembly of Behavioral and Social Sciences National Research Council.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75447,"journal":{"name":"Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18205079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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