Annali dell'Ospedale Maria Vittoria di Torino最新文献

A method to reduce blood pressure for helping middle ear peculiar surgery was evaluated in this study. TNT administered in slow intravenous drip, in association with NLA, permitted to obtain a quick and well controlled hypotension without the incidence of significant adverse reactions.

The first part of the work deals with voluntary abortion recidivity. A casuistry of about 200 cases, divided into several groups according to the age, is considered. It is compared to the official data of Italy and other countries. The second part deals with the relationship between voluntary abortion and contraception. Some concrete proposals to reduce the number of voluntary abortions are presented.

The dental pattern allows a taxonomic assignment of a primate and some deductions about his food preference and survival behaviour. The purpose is to define the Hominid's diet and behaviour, through a dental study. The Australopithecines teeth pattern was human like and quite different from Pongid pattern. Author indicates differential dental marks of A. robustus, A. gracilis and Homo Habilis, and infers, also by environmental knowledge, that they, very likely, were fruits, roots, graminivorous eaters, using their hands in preparing the food with rudimental skill. Their diet maybe was carnivorous too and their teeth were'nt quite specialized. Instead A. Robustus teeth were super-specialized for hard, coriaceus, vegetal food, and so their molars are enormous and powerful, while lacked in advanced hand skill. Homo Habilis shows dental small size like present human's teeth. Very likely, they were able to prepare food by tools, with better manual skill, and their diet had more variety (onnivorous). With hominization increasing, the teeth were decreasing in size and were loosing specialization, while hominids were gaining another functional skillness.

The literature of the past ten years shows that the introduction of highly purified heterologous and, lastly, homologous insulins has notably lowered the production of IgG and IgE specific insulin antibodies, but has not succeeded in completely eliminating clinical manifestations of the immune or hyper-immune response to insulin therapy. In particular, insulin allergy with or without lipodystrophy is still seen. Among the factors of insulin immunogenicity, there is a possible genetic control of the immune response in type I diabetes: determining HLA halloantigens (A, B, C, D) might identify specific immune response genes (Ir genes). Initial researches, performed until now almost exclusively upon diabetics treated with conventional heterologous insulin, seem to indicate a positive relationship between haplotype HLA - B15 - DR4 and an elevated immune response, whereas haplotypes HLA - B8 - DR3 and HLA - B18 - DR3 might protect against the formation of anti-insulin antibodies. Antigens D/DR3 and D/DR4 are known to be primitively associated to susceptibility for type I diabetes, whereas antigens B8, B15, B18 are secondarily associated to the rise in frequency of DR3 and DR4 for the "linkage disequilibrium" existing between alleles of B and D loci. The results of HLA typing are presented in 2 groups of insulin-dependent diabetics (ID) followed from an immunological viewpoint during therapy with monocomponent heterologous insulin for over 5 years. The first group is composed of 50 patients with low IgG anti-insulin antibody titers (less than 1 mU/ml, Christiansen: low responders); the second group is made up of 23 patients with high IgG anti-insulin antibody titers (greater than 2.5 mU/ml, Christiansen: high responders) and includes 5 subjects with insulin allergy (associated or not with insulin lipoatrophy) and high levels of insulin specific IgE antibodies. A study of the frequencies of various HLA-B antigens in both groups of patients, in regard to a control group of piemontese population, in relation to the intensity of association (relative risk) and to the statistical importance of frequencies, shows only a possible protective effect of the HLA-B18 phenotype (linkage disequilibrium with HLA - DR3) towards the production of anti-insulin antibodies and hyperimmune clinical manifestations, such as allergy. Reliable conclusions are not possible between low and high responders for the other phenotypes (HLA - B7, B8, B15) commonly implicated. HLA-B12 was noted in 3 of 5 patients with allergy, in 2 cases associated with B8.(ABSTRACT TRUNCATED AT 400 WORDS)

The Authors have developed a retrospective study of 45 patients, suffering from acute pancreatitis and hospitalized at a general surgery Departement during a period of two years. The purpose of the study was to evaluate the validity of the classification of acute pancreatitis in three degrees (slight, moderate, serious), suggested by Hollender to prognostic and therapeutic aims.

Hepatic traumas are one of the most common sequelae of abdominal injuries. The Authors report 24 cases of hepatic traumas about a casuistry of 104 patients, that, in the decade '74-'84, had an abdominal traumatism. The quality of injuries, the therapeutic actions, and results are described.

In the first part the authors report a nosological review of the obstructions of the bladder neck and urethra in childhood and present the most typical radiological aspects of the most important obstructive uropathies. In the second part they illustrate their cases, that include 11 patients between 0 and 10 years, of which 4 males, with urethral valves; 2 females, with external urethral meatus stenosis; 1 male, with non valvular stenosis of urethra: 2 one male and one female, with extrinsic obstruction by ectopic ureterocele; and 2 females, with neurologic bladder. The authors point out the cases with obstruction by posterior urethral valves and by ectopic ureterocele, mainly for the severe hydrodynamic effects of low obstruction on bladder, ureters and pelvis; the authors present, in some cases, also later radiological examinations, obtained after surgical removal of the obstruction. The two cases of neurological bladder are presented in order to point out the difficulty of an exclusively radiological differential diagnosis between some cases of true mechanical obstruction and obstruction caused by neuromuscular disorder of low urinary tract. At last the Authors confirm again the usefulness, but also the limits, of the radiological examination alone in diagnosis of the obstructions of bladder neck and urethra in childhood.