The authors describe the most common techniques of mechanical ventilation in the newborn's respiratory distress syndrome (RDS) and the most qualified modalities in the different pathological situations.
The authors describe the most common techniques of mechanical ventilation in the newborn's respiratory distress syndrome (RDS) and the most qualified modalities in the different pathological situations.
The main pathogenetic moment of the respiratory distress syndrome (RDS) is recognized to be the lack of alveolar surfactant. Many attempts of substitutive therapy with several kinds of surfactants have been tried (artificial, synthetic, from amniotic fluid, exosurf). After the considerable results obtained in animals, the use of substitutive surfactant proved to be useful also in human newborns with RDS. The authors report the personal data relative to the TA-surfactant (artificial surfactant made of phospholipids + DPPC + protein substances extracted from bovine lung). They analyse first results and, on this ground, they put forward some assumptions in order to obtain a more rational and efficient use.
Liposarcoma of the spermatic cord is a rare tumour, usually well differentiated, that generally resembles a lipoma and undergoes a slow, progressive enlargement. Most patients with liposarcoma do not experience any recurrence after local excision. Due to the rare occurrence of this tumour it seems appropriate to document one case that came to our observation in recent years.
A simplified approach to the management of major lesions of the diabetic foot is presented. Two nosological types, the angiopathic foot and the neuropathic foot, are proposed, on the basis of diagnostic, therapeutic, prognostic and preventive criteria. A ten years personal experience is discussed.
In our hospital, 199 patients following oral anticoagulant therapy were studied and controlled. They were divided into two groups according to the follow-up period. The first group was treated for 24-40 weeks. The second group was treated for 6-24 weeks. In the first group, 169 (98.3%) of the 172 patients studied maintained therapeutic range INR (2.1-4.8) for a period of 70%-100% of the total observation time, whereas 3 patients (1.7%) did not have a valid therapeutic response. The percentage of subjects within therapeutic range in the second group of 27 patients was decidedly inferior. Five of these patients were not able to achieve the desired results, probably because of a too brief period and undertreatment.
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