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Speech perception test for Arabic-speaking children. 阿拉伯语儿童语言感知测试。
L Kishon-Rabin, J Rosenhouse

The high incidence of hearing impairment in the Arabic-speaking population in Israel, as well as the use of advanced aural rehabilitation devices, motivated the development of Arabic speech assessment tests for this population. The purpose of this paper is twofold. The first goal is to describe features that are unique to the Arabic language and that need to be considered when developing such speech tests. These include Arabic diglossia (i.e., the sharp dichotomy between Literary and Colloquial Arabic), emphatization, and a simple vowel system. The second goal is to describe a new analytic speech test that assesses the perception of significant phonological contrasts in the Colloquial Arabic variety used in Israel. The perception of voicing, place, and manner of articulation, in both initial and final word positions, was tested at four sensation levels in 10 normally-hearing subjects using a binary forced-choice paradigm. Results show a relationship between percent correct and presentation level that is in keeping with articulation curves obtained with Saudi Arabic and English monosyllabic words. Furthermore, different contrasts yielded different articulation curves: emphatization was the easiest to perceive whereas place of articulation was the most difficult. The results can be explained by the specific acoustical features of Arabic.

在以色列讲阿拉伯语的人口中,听力损伤的发生率很高,加上使用了先进的听力康复设备,促使为这一人口开发阿拉伯语语音评估测试。本文的目的是双重的。第一个目标是描述阿拉伯语独有的特征,在开发这种语音测试时需要考虑这些特征。这些包括阿拉伯语的双叙(即,阿拉伯语文学和口语之间的尖锐二分法),重音和简单的元音系统。第二个目标是描述一种新的分析性言语测试,该测试评估了以色列使用的口语阿拉伯语变体中重要语音对比的感知。使用二元强迫选择范式,对10名听力正常的受试者在四个感觉水平上对初始和最终单词位置的发声、位置和发音方式的感知进行了测试。结果表明,正确率与表达水平之间的关系符合沙特阿拉伯语和英语单音节单词的发音曲线。此外,不同的对比产生了不同的发音曲线:强调是最容易感知的,而发音的位置是最难感知的。这些结果可以用阿拉伯语特有的声学特征来解释。
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引用次数: 0
Nucleus 21-channel auditory brainstem implant in patients with previous tumour removal. 核21通道听觉脑干植入在既往肿瘤切除患者中的应用。
H Wu, M Kalamarides, D Bouccara, E A Dahan, W P Sollmann, P Viala, A Rey, O Sterkers

Three patients with neurofibromatosis type 2 who had undergone previous cochlear nerve tumour removal were implanted with the Nucleus 21-channel auditory brainstem implant (ABI). The time intervals between tumour removal and implantation were 4, 5, and 7 years, respectively. Total bilateral deafness was confirmed before implantation. One patient was also blind after acute intracranial hypertension. The translabyrinthine approach was used in all cases. The choice of side for implantation depended on pre-operative magnetic resonance imaging study, the facial nerve function, the presence of recurrent and/or other lesions, and the patient's preference. Although the scarring of prior surgical procedure largely changed the anatomical structures in the cerebello-pontine angle, various landmarks could be found to locate the foramen of Luschka, where the ABI electrode was inserted into the lateral recess of the fourth ventricle. During surgery, the electrically evoked auditory brainstem responses were recorded to confirm that the ABI stimulation activated the auditory system; the electromyogram of the 7th and 9th nerves was helpful in finding the landmarks and minimising the triggering of the cranial nerves with ABI stimulation. The number of active electrodes was 21, 7, and 4 in the three patients. All obtained meaningful pitch scaling and useful auditory sensations. One patient, with 21 activated electrodes, has achieved functional open-set speech understanding. The second patient, with 7 activated electrodes, has benefited from environmental sound awareness and improved lipreading. The last, blind, patient, with 4 electrodes activated, achieved only perception of environmental sounds.

本文对3例2型神经纤维瘤病患者行耳蜗神经肿瘤切除术后植入21通道听觉脑干植入物(ABI)。肿瘤切除至植入术的时间间隔分别为4年、5年和7年。植入前确诊双侧全聋。1例患者在急性颅内高压后也失明。所有病例均采用经迷路入路。植入侧位的选择取决于术前磁共振成像研究、面神经功能、复发和/或其他病变的存在以及患者的偏好。虽然先前手术的疤痕很大程度上改变了小脑-桥脑角的解剖结构,但可以找到各种标志来定位Luschka孔,ABI电极被插入第四脑室的外侧隐窝。手术过程中,记录电诱发的听觉脑干反应,以证实ABI刺激激活了听觉系统;第7和第9神经的肌电图有助于找到标志,并尽量减少ABI刺激对脑神经的触发。3例患者的有效电极数分别为21、7、4个。所有人都获得了有意义的音高缩放和有用的听觉感觉。一名患者使用了21个激活电极,实现了功能性的开放集语言理解。第二个病人,有7个激活电极,受益于环境声音意识和唇读能力的提高。最后一组是盲人患者,激活了4个电极,只能感知环境声音。
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引用次数: 0
Ototoxic interaction between noise and pheomelanin: distortion product otoacoustic emissions after acoustical trauma in chloroquine-treated red, black, and albino guinea pigs. 噪音和黑色素之间的耳毒性相互作用:氯喹处理的红、黑和白化豚鼠声损伤后的畸变产物耳声发射。
M L Barrenäs, K M Holgers

This study provides further evidence of an ototoxic interaction between red pheomelanin pigmentation and noise-induced hearing loss. Red, black, and albino guinea pigs were treated with a low, a high, or no dose of chloroquine. The 2f1-f2 distortion product otoacoustic emission (DPOE) measurements were measured before, immediately after, and 1 month after noise exposure to a 1-kHz tone at 105 dB SPL for 72 hours. In red guinea pigs, the DPOE was severely affected by noise trauma when treated even by a low single dose of chloroquine, whereas in both albino and black guinea pigs, the chloroquine effect on the DPOE was temporary and present only when the drug was given in a high single dose. The structure most likely to be responsible for the severe loss of DPOE in chloroquine-treated red animals is the strial melanocyte. The damage may be triggered by an ototoxic noise-induced production of radical oxygen species from pheomelanin, for example, by the Fenton reaction or due to the increased variability of the melanocyte 1 receptor gene as in red-haired individuals.

这项研究提供了进一步的证据,证明红色现象黑色素沉着与噪音性听力损失之间存在耳毒性相互作用。红豚鼠、黑豚鼠和白化豚鼠分别接受低剂量、高剂量或无剂量的氯喹治疗。在105 dB SPL的1 khz噪声下暴露72小时之前、之后和1个月后测量了2f1-f2失真乘积耳声发射(DPOE)。在红色豚鼠中,即使单次低剂量氯喹也会严重影响DPOE,而在白化豚鼠和黑色豚鼠中,氯喹对DPOE的影响是暂时的,只有在单次高剂量给药时才会出现。在氯喹处理过的红色动物中,最可能导致DPOE严重丧失的结构是黑素细胞。损伤可能是由耳毒性噪声引起的由黑色素产生的自由基氧引起的,例如,通过芬顿反应,或者由于黑素细胞1受体基因的变异性增加,如在红发个体中。
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引用次数: 0
Prevalence of sensorineural hearing loss in children in Costa Rica. 哥斯达黎加儿童感音神经性听力损失患病率
Pub Date : 2000-09-01 DOI: 10.3109/00206090009073092
G T Mencher, J J Madriz Alfaro

There is very limited information available about hearing loss in children in Latin America and in Central America in particular. Costa Rica is a peaceful, well-organized country with an excellent health care system and a very good infrastructure of roads, programs, and services. It served as the site for a four-phase study to determine the incidence and prevalence rate for sensorineural hearing loss in children in that region of the world. The four phases involved (1) screening over 12,500 children in the public schools, (2) examining those enrolled at programs for the hearing impaired, (3) searching the community for children not in schools or special programs, and (4) an extensive questionnaire designed to obtain basic demographic data about hearing-impaired children in the country. Included were questions about age of identification, etiology, and hearing aid use. Results of phases 1 and 2 are reported here. Using a 1.368 per 1,000 live birth average (a figure reported for 36 nations), the projected number of hearing-impaired children in Costa Rica should be about 1,068. After concluding the first two phases of the study, it was determined that the actual number of hearing-impaired children in Costa Rica is between 1,174 and 1,274. That is a ratio of between 1.50 and 1.63 hearing impaired per 1,000 live births, well within the ranges reported elsewhere. Since this is the first national study of a Latin American country, that information is significant, suggesting that the general prevalence of hearing loss in that part of the world is the same as in the developed nations of Europe and North America.

关于拉丁美洲和中美洲儿童听力损失的信息非常有限。哥斯达黎加是一个和平、组织有序的国家,拥有出色的医疗保健系统和非常好的道路、项目和服务基础设施。它是一项四阶段研究的地点,旨在确定该地区儿童感音神经性听力损失的发病率和流行率。这四个阶段包括:(1)在公立学校筛选超过12500名儿童,(2)检查参加听障项目的儿童,(3)在社区寻找不在学校或特殊项目的儿童,以及(4)设计广泛的问卷调查,以获得该国听障儿童的基本人口统计数据。问题包括年龄、病因和助听器使用情况。第1和第2阶段的结果在此报告。按照每1000名活产婴儿中平均有1.368名活产婴儿(36个国家的报告数据)计算,哥斯达黎加的听力受损儿童预计将达到约1068名。在结束前两个阶段的研究后,确定哥斯达黎加听力受损儿童的实际人数在1174到1274之间。也就是说,每1000名活产婴儿中听力受损的比例在1.50至1.63之间,完全在其他地方报道的范围之内。由于这是对拉丁美洲国家的首次全国性研究,该信息意义重大,表明该地区听力损失的普遍流行程度与欧洲和北美的发达国家相同。
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引用次数: 25
Predictive factors for the severity of tinnitus. 耳鸣严重程度的预测因素。
Pub Date : 2000-09-01 DOI: 10.3109/00206090009073093
K M Holgers, S I Erlandsson, M L Barrenäs

The majority of patients with tinnitus experience a lessening of their symptoms during an 18-month period after their first consultation. The exception to this rule is severe incapacitating tinnitus, the sometimes very troublesome symptoms of which show no sign of diminishing with time. The aim of the present study was to investigate risk factors for incapacitating tinnitus, as measured by absence from work related to tinnitus (AWT) of more than 1 month during an 18-month period after the first visit to the tinnitus clinic. Audiometric data and the scores from the Tinnitus Severity Questionnaire and the Nottingham Health Profile at the first visit to the clinic were correlated to AWT by a logistic regression model. By using this risk model, an individual risk score for AWT could be estimated. Depression and physical immobility were strong predictors of AWT, and hearing loss was moderate. Based on these results, we suggest that the aetiology of tinnitus severity could be described as depression-/anxiety-related, somatic, and auditory tinnitus.

大多数耳鸣患者在第一次咨询后的18个月内症状减轻。这个规则的例外是严重的失能性耳鸣,有时非常麻烦的症状,其中没有显示出减少的迹象随着时间的推移。本研究的目的是调查失能性耳鸣的危险因素,通过首次就诊耳鸣诊所后18个月内因耳鸣而缺工超过1个月来测量。首次就诊时的听力数据、耳鸣严重程度问卷和诺丁汉健康概况评分与AWT通过逻辑回归模型相关。通过使用该风险模型,可以估计出AWT的个体风险评分。抑郁和身体不活动是AWT的强预测因子,听力损失为中度。基于这些结果,我们认为耳鸣严重程度的病因可以描述为抑郁/焦虑相关,躯体耳鸣和听觉耳鸣。
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引用次数: 50
Characteristics of the inflammatory process around skin-penetrating titanium implants for aural rehabilitation. 皮肤穿透性钛耳聋康复植入物周围炎症过程的特点。
K M Holgers

Skin-penetrating titanium implants have been used to anchor bone-anchored hearing aids (BAHAs) since 1977. The aim of the present immunohistochemical study was to analyse the distribution of inflammatory cell types in the skin penetration site with a panel of monoclonal antibodies. Many inflammatory cells were present at the tissue-implant interface but decreased gradually in number from the interface. The predominating cell types in the dermis in clinically non-inflamed tissue were T lymphocytes and macrophages, indicating a chronic inflammatory response. In specimens from clinically inflamed tissue, a large number of polymorphonuclear positive cells were present. B lymphocytes and plasma cells were also found, indicating that bacterial infections were superimposed on the chronic inflammatory response. An additional aim was to revise the clinical scoring system based on the present findings and earlier histological results.

自1977年以来,皮肤穿透钛植入物已被用于锚定骨锚定助听器(BAHAs)。目前的免疫组织化学研究的目的是分析炎症细胞类型的分布在皮肤穿透部位与一组单克隆抗体。在组织-种植体界面处有许多炎症细胞,但从界面处逐渐减少。在临床非炎症组织中,真皮中主要的细胞类型是T淋巴细胞和巨噬细胞,表明慢性炎症反应。在临床炎症组织的标本中,存在大量的多形核阳性细胞。B淋巴细胞和浆细胞也被发现,表明细菌感染叠加在慢性炎症反应上。另一个目的是根据目前的发现和早期的组织学结果修改临床评分系统。
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引用次数: 0
Field trials using a digital hearing aid with active noise reduction and dual-microphone directionality. 现场试验使用具有主动降噪和双麦克风定向的数字助听器。
Pub Date : 2000-09-01 DOI: 10.3109/00206090009073090
M Boymans, W A Dreschler

In this study, we measured the effects of a digital hearing aid on speech recognition or reception in noise for two noise reduction concepts: active noise reduction by speech-sensitive processing (SSP) and improved directionality by a dual- or so-called twin-microphone system (TMS). This was conducted in a well-controlled clinical field trial in 16 hearing-aid users, using a single-blind crossover design. The hearing aid fitting was controlled by insertion gain measurements and measurements with loudness scaling. This study combined laboratory experiments with three consecutive field trials of 4 weeks each. We used performance measurements (speech recognition tests in background noise), paired comparisons, and self-report measurements (questionnaires). The speech recognition or reception tests were performed before and after each field trial, the paired comparisons were performed in weeks 4 and 12, and the questionnaires were administered after each field trial. For all subjects, results were obtained for three different settings: no noise reduction, SSP alone, and TMS alone. In the last week, we also performed speech recognition or reception tests in background noise with both noise reduction concepts combined. Three types of results have been reported: "objective" results from the critical signal to noise ratios for speech recognition or reception in different background noises for different settings and "subjective" results: paired comparisons and questionnaires. The subjective scores show the same trend as the objective scores. The effects of TMS were clearly positive, especially for the speech reception threshold tests and for the paired comparisons. The effects of SSP were much smaller but showed significant benefits with respect to aversiveness and speech perception or reception in noise for specific acoustical environments. There was no extra benefit from the combined effect of SSP and TMS relative to TMS alone.

在这项研究中,我们测量了数字助听器在噪声中对语音识别或接收的影响,这两种降噪概念是:通过语音敏感处理(SSP)主动降噪,以及通过双麦克风系统(TMS)改善方向性。这是在16名助听器使用者中进行的一项控制良好的临床现场试验,采用单盲交叉设计。通过插入增益测量和响度标度测量来控制助听器的装配。本研究将室内实验与连续三次、每次4周的田间试验相结合。我们使用了性能测量(背景噪声下的语音识别测试)、配对比较和自我报告测量(问卷调查)。在每次现场试验前后分别进行语音识别或接收测试,在第4周和第12周进行配对比较,并在每次现场试验后进行问卷调查。对于所有受试者,在三种不同的设置下获得结果:不降噪、单独使用SSP和单独使用TMS。在上周,我们还进行了背景噪声下的语音识别或接收测试,将两种降噪概念结合起来。报告了三种类型的结果:“客观”结果,即在不同设置的不同背景噪声下语音识别或接收的关键信噪比;“主观”结果:配对比较和问卷调查。主观得分与客观得分呈现相同的趋势。经颅磁刺激的效果明显是积极的,尤其是在语音接收阈值测试和配对比较中。SSP的影响要小得多,但在特定声学环境中对厌恶和语音感知或接收方面显示出显著的好处。与单独经颅磁刺激相比,SSP和经颅磁刺激联合作用没有额外的益处。
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引用次数: 115
Aging and external ear resonance. 衰老与外耳共振。
T C Liu, Y S Chen

External ear resonance was measured in elderly people using a probe-tube microphone system. Resonance frequency, amplitude, and bandwidth as well as ear canal volume were compared across age groups and genders. No significant age group trends were observed in external ear resonant frequency. Also, the amplitude and bandwidth of the resonance peaks across ages were not significantly different. For the gender effect, the mean external ear resonant frequencies are generally higher for females than for males in all age groups, but the differences are not statistically significant. The mean amplitudes of the resonant frequency are larger for men than for women. But the difference is also small. For the ear canal volume, no significant age trend was found. However, the mean ear canal volume was significantly larger for males than for females.

使用探针管麦克风系统测量老年人外耳共振。共振频率、振幅和带宽以及耳道容积在不同年龄组和性别之间进行比较。外耳共振频率无明显年龄组变化趋势。不同年龄的共振峰振幅和带宽无显著差异。性别效应方面,各年龄组女性外耳平均共振频率普遍高于男性,但差异无统计学意义。男性共振频率的平均振幅比女性大。但差别也很小。耳道容积无明显的年龄变化趋势。然而,男性的平均耳道容积明显大于女性。
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引用次数: 0
Hearing impairment in Latin America: an inventory of limited options and resources. 拉丁美洲的听力障碍:有限选择和资源的清单。
Pub Date : 2000-07-01 DOI: 10.3109/00206090009073081
J J Madriz

The availability of information about prevalence/incidence of hearing impairment in Latin American countries is very limited. A questionnaire on the subject was mailed to most Latin American and Caribbean countries. The information returned by 12 respondents (Argentina, Chile. Columbia, Costa Rica, Cuba, Grenada, Guatemala, Mexico, Nicaragua, Panama, Puerto Rico, and Uruguay) was analyzed. Data are presented about available epidemiological studies on hearing impairment, national registers on deafness, publications on otitis media, and programs on hearing screening. Presence of training programs and available human resources in the broad field of hearing impairment is also discussed. Estimates of the enrollment of deaf children in schools for the deaf is also shown. This review concludes that hearing impairment is a low priority for national health systems in Latin America. material and human resources are limited, audiology services are scarce, and technology continues to be very costly by regional standards.

在拉丁美洲国家,有关听力损害流行/发病率的信息非常有限。已向大多数拉丁美洲和加勒比国家邮寄了一份关于这个问题的调查表。12个答复国(阿根廷、智利。哥伦比亚、哥斯达黎加、古巴、格林纳达、危地马拉、墨西哥、尼加拉瓜、巴拿马、波多黎各和乌拉圭)进行了分析。资料包括现有的听力障碍流行病学研究、国家耳聋登记、中耳炎出版物和听力筛查项目。培训计划的存在和现有的人力资源在听力障碍的广泛领域也进行了讨论。聋哑儿童在聋哑学校的入学人数估计也显示出来。本综述的结论是,拉丁美洲国家卫生系统对听力障碍的重视程度较低。物质和人力资源有限,听力学服务稀缺,而且按照区域标准,技术仍然非常昂贵。
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引用次数: 32
Challenge of epidemiological research in the developing world: overview. 发展中国家流行病学研究的挑战:概述。
G T Mencher

Listing the eight most important aspects of epidemiological research relevant to hearing loss, this paper reviews some of the difficulties encountered in trying to do such research in the developing world. Various research formats are discussed. This paper concludes with a review of what has been reported in the world's literature about the incidence and prevalence of sensorineural hearing loss in children. The average finding from 34 nations is 1.368 hearing impaired per 1,000.

本文列举了与听力损失有关的流行病学研究的八个最重要方面,回顾了在发展中国家进行此类研究时遇到的一些困难。讨论了各种研究形式。本文总结了世界上关于儿童感音神经性听力损失的发病率和患病率的文献报道。34个国家的平均结果是每1000人中有1368名听力受损。
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引用次数: 0
期刊
Audiology : official organ of the International Society of Audiology
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