首页 > 最新文献

Hospital practice最新文献

英文 中文
Perioperative management of dual anti-platelet therapy 双重抗血小板治疗的围手术期管理
Pub Date : 2016-10-19 DOI: 10.1080/21548331.2016.1260997
Tyler Webster, Prashant Vaishnava, K. Eagle
ABSTRACT Dual anti-platelet therapy denotes a regimen of aspirin plus a P2Y12 receptor inhibitor, clopidogrel, prasugrel, or ticagrelor. Such therapy is a cornerstone of medical management following acute coronary syndromes and is imperative following percutaneous coronary interventions. While there is uncertainty about the optimal duration of dual antiplatelet therapy following percutaneous coronary intervention, the new 2016 American College of Cardiology/American Heart Association Guidelines suggest that for patients with stable ischemic heart disease at least six months of such therapy following a drug eluting stent and one month following a bare metal stent should be implemented. In patients with acute coronary syndrome including non-ST elevation and ST elevation myocardial infarction it is recommended to extend dual antiplatelet therapy treatment to one year in both drug eluting stent and bare metal stent groups. There may be latitude for earlier discontinuation in appropriately selected patients; extended dual antiplatelet therapy beyond one year may be beneficial in others. Herein, we describe current guidelines and evidence supporting if and when dual antiplatelet therapy should be interrupted for surgery for patients who have undergone percutaneous coronary intervention.
双重抗血小板治疗是指阿司匹林加P2Y12受体抑制剂氯吡格雷、普拉格雷或替格瑞的治疗方案。这种治疗是急性冠状动脉综合征后医疗管理的基石,也是经皮冠状动脉介入治疗后必不可少的。虽然经皮冠状动脉介入治疗后双重抗血小板治疗的最佳持续时间尚不确定,但新的2016年美国心脏病学会/美国心脏协会指南建议,对于稳定性缺血性心脏病患者,应在药物洗脱支架后至少进行6个月的双重抗血小板治疗,在裸金属支架后至少进行1个月的双重抗血小板治疗。对于包括非ST段抬高和ST段抬高型心肌梗死在内的急性冠脉综合征患者,建议药物洗脱支架组和裸金属支架组均延长双抗血小板治疗至1年。在适当选择的患者中,可能有提前停药的余地;延长双重抗血小板治疗超过一年可能对其他患者有益。在此,我们描述了目前的指南和证据,支持是否以及何时应该中断双重抗血小板治疗,以进行经皮冠状动脉介入治疗的患者。
{"title":"Perioperative management of dual anti-platelet therapy","authors":"Tyler Webster, Prashant Vaishnava, K. Eagle","doi":"10.1080/21548331.2016.1260997","DOIUrl":"https://doi.org/10.1080/21548331.2016.1260997","url":null,"abstract":"ABSTRACT Dual anti-platelet therapy denotes a regimen of aspirin plus a P2Y12 receptor inhibitor, clopidogrel, prasugrel, or ticagrelor. Such therapy is a cornerstone of medical management following acute coronary syndromes and is imperative following percutaneous coronary interventions. While there is uncertainty about the optimal duration of dual antiplatelet therapy following percutaneous coronary intervention, the new 2016 American College of Cardiology/American Heart Association Guidelines suggest that for patients with stable ischemic heart disease at least six months of such therapy following a drug eluting stent and one month following a bare metal stent should be implemented. In patients with acute coronary syndrome including non-ST elevation and ST elevation myocardial infarction it is recommended to extend dual antiplatelet therapy treatment to one year in both drug eluting stent and bare metal stent groups. There may be latitude for earlier discontinuation in appropriately selected patients; extended dual antiplatelet therapy beyond one year may be beneficial in others. Herein, we describe current guidelines and evidence supporting if and when dual antiplatelet therapy should be interrupted for surgery for patients who have undergone percutaneous coronary intervention.","PeriodicalId":75913,"journal":{"name":"Hospital practice","volume":"44 1","pages":"237 - 241"},"PeriodicalIF":0.0,"publicationDate":"2016-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.2016.1260997","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60073654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Recent advances in the management of pericardial diseases 心包疾病治疗的最新进展
Pub Date : 2016-10-19 DOI: 10.1080/21548331.2016.1265416
D. Celentani, M. di Cuia, M. Imazio, F. Gaita
ABSTRACT Pericardial diseases are relatively common in clinical practice either as isolated diseases or part of an underlying or systemic disease. Recent advances in the diagnosis and treatment have greatly improved the clinical management and lead to consensus documents on multimodality imaging and new guidelines on the diagnosis and therapy of pericardial diseases. The aim of the present paper is to summarize available evidence in order to provide an updated and comprehensive review on the recent advances in the management of pericardial diseases.
心包疾病在临床实践中是相对常见的,无论是作为孤立的疾病,还是作为基础或全身性疾病的一部分。近年来在诊断和治疗方面的进展极大地改善了临床管理,并在多模态影像学和新的诊断和治疗指南方面取得了共识。本文的目的是总结现有的证据,以便对心包疾病治疗的最新进展提供一个更新和全面的回顾。
{"title":"Recent advances in the management of pericardial diseases","authors":"D. Celentani, M. di Cuia, M. Imazio, F. Gaita","doi":"10.1080/21548331.2016.1265416","DOIUrl":"https://doi.org/10.1080/21548331.2016.1265416","url":null,"abstract":"ABSTRACT Pericardial diseases are relatively common in clinical practice either as isolated diseases or part of an underlying or systemic disease. Recent advances in the diagnosis and treatment have greatly improved the clinical management and lead to consensus documents on multimodality imaging and new guidelines on the diagnosis and therapy of pericardial diseases. The aim of the present paper is to summarize available evidence in order to provide an updated and comprehensive review on the recent advances in the management of pericardial diseases.","PeriodicalId":75913,"journal":{"name":"Hospital practice","volume":"44 1","pages":"266 - 273"},"PeriodicalIF":0.0,"publicationDate":"2016-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.2016.1265416","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60073675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Hospitalist-vascular surgery comanagement: effects on complications and mortality 住院医师血管手术管理:对并发症和死亡率的影响
Pub Date : 2016-10-19 DOI: 10.1080/21548331.2016.1259543
Colin T Iberti, A. Briones, Erin Gabriel, A. Dunn
ABSTRACT Objectives: Hospitalized vascular surgery patients have multiple severe comorbidities, poor functional status, and high perioperative cardiac risk. Thus they may be ideal patients for a collaborative care model. However, there is little evidence for a comanagement model on clinical outcomes. Methods: The two-year pre-post study consisted of a comanagement model where a hospitalist actively participated in the medical care of American Society of Anesthesiologist Physical Status Classification scale 3 or 4 vascular surgery patients. Outcomes were in-hospital mortality, length of stay, 30-day readmission rate, pain scores, and patient safety metrics. Results: With comanagement, patient complications decreased from 3.5 to 2.2 events per 1000 patients. (p = 0.045). Mortality decreased from 2.01% to 1.00% (p = 0.049), corresponding to a decrease in the risk-adjusted observed to expected mortality rate ratio from 1.22 to 0.53 (p = 0.01). Patient reported pain scores improved; more patients in the comanagement cohort expressed no pain (72% vs 82.8%; p = 0.01) and there were reductions in reports of mild and moderate pain. There was no significant difference in the risk-adjusted length of stay (observed to expected ratio 0.83 to 0.88 for the pre-intervention and comanagement groups, respectively, p = 0.48). The 30-day readmission rate was unchanged (21.9 vs 20.6% p = 0.44). Patients in the intervention period were more clinically complex, as evidenced by the greater case mix index (2.21 vs 2.44). Conclusions: After two years of implementation, our comanagement service reduced complications, mortality, and pain scores among high-risk vascular surgery patients.
目的:血管外科住院患者存在多种严重合并症,功能状态差,围手术期心脏风险高。因此,他们可能是合作护理模式的理想患者。然而,很少有证据表明临床结果的管理模式。方法:采用一名住院医师积极参与美国麻醉医师协会身体状态分类量表3、4例血管手术患者医疗护理的管理模式,进行为期两年的前后研究。结果包括住院死亡率、住院时间、30天再入院率、疼痛评分和患者安全指标。结果:通过管理,患者并发症从每1000例患者3.5例下降到2.2例。(p = 0.045)。死亡率从2.01%降至1.00% (p = 0.049),对应于经风险调整的观察死亡率与预期死亡率之比从1.22降至0.53 (p = 0.01)。患者报告的疼痛评分改善;管理组中更多的患者没有疼痛(72% vs 82.8%;P = 0.01),轻度和中度疼痛的报告有所减少。经风险调整后的住院时间没有显著差异(干预前组和管理组的观察比和预期比分别为0.83和0.88,p = 0.48)。30天再入院率不变(21.9 vs 20.6% p = 0.44)。干预期患者的临床复杂程度更高,病例混合指数更高(2.21 vs 2.44)。结论:经过两年的实施,我们的管理服务降低了高危血管手术患者的并发症、死亡率和疼痛评分。
{"title":"Hospitalist-vascular surgery comanagement: effects on complications and mortality","authors":"Colin T Iberti, A. Briones, Erin Gabriel, A. Dunn","doi":"10.1080/21548331.2016.1259543","DOIUrl":"https://doi.org/10.1080/21548331.2016.1259543","url":null,"abstract":"ABSTRACT Objectives: Hospitalized vascular surgery patients have multiple severe comorbidities, poor functional status, and high perioperative cardiac risk. Thus they may be ideal patients for a collaborative care model. However, there is little evidence for a comanagement model on clinical outcomes. Methods: The two-year pre-post study consisted of a comanagement model where a hospitalist actively participated in the medical care of American Society of Anesthesiologist Physical Status Classification scale 3 or 4 vascular surgery patients. Outcomes were in-hospital mortality, length of stay, 30-day readmission rate, pain scores, and patient safety metrics. Results: With comanagement, patient complications decreased from 3.5 to 2.2 events per 1000 patients. (p = 0.045). Mortality decreased from 2.01% to 1.00% (p = 0.049), corresponding to a decrease in the risk-adjusted observed to expected mortality rate ratio from 1.22 to 0.53 (p = 0.01). Patient reported pain scores improved; more patients in the comanagement cohort expressed no pain (72% vs 82.8%; p = 0.01) and there were reductions in reports of mild and moderate pain. There was no significant difference in the risk-adjusted length of stay (observed to expected ratio 0.83 to 0.88 for the pre-intervention and comanagement groups, respectively, p = 0.48). The 30-day readmission rate was unchanged (21.9 vs 20.6% p = 0.44). Patients in the intervention period were more clinically complex, as evidenced by the greater case mix index (2.21 vs 2.44). Conclusions: After two years of implementation, our comanagement service reduced complications, mortality, and pain scores among high-risk vascular surgery patients.","PeriodicalId":75913,"journal":{"name":"Hospital practice","volume":"44 1","pages":"233 - 236"},"PeriodicalIF":0.0,"publicationDate":"2016-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.2016.1259543","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60073999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Role of hospitalists in the diagnosis of atrial fibrillation for the management of cryptogenic stroke patients 医院医生在诊断房颤对隐源性脑卒中患者管理中的作用
Pub Date : 2016-10-19 DOI: 10.1080/21548331.2016.1258292
A. Amin
ABSTRACT Cryptogenic strokes are responsible for significant morbidity and mortality. Identifying the underlying cause of cryptogenic stroke is imperative for appropriate short and long-term management of these patients. In particular, detecting atrial fibrillation in cryptogenic stroke patients may shed insight into the cause of the index stroke, but is also important to identify an important cause of secondary stroke. There is accumulating evidence indicating that monitoring for durations beyond the guideline recommended 30 day-period results in greater atrial fibrillation yield. This article reviews current guidelines and practices for the diagnosis of cryptogenic stroke, as well as outpatient cardiac monitoring options available, and focuses on the role that hospitalists have to play in the care of these patients.
隐源性中风的发病率和死亡率都很高。确定隐源性卒中的潜在原因对于这些患者的适当短期和长期管理是必要的。特别是,在隐源性脑卒中患者中检测心房颤动可能有助于了解指数脑卒中的原因,但对于确定继发性脑卒中的重要原因也很重要。越来越多的证据表明,监测时间超过指南推荐的30天会导致更大的房颤发生率。本文回顾了隐源性卒中诊断的现行指南和实践,以及可用的门诊心脏监测选择,并重点介绍了医院医生在这些患者的护理中必须发挥的作用。
{"title":"Role of hospitalists in the diagnosis of atrial fibrillation for the management of cryptogenic stroke patients","authors":"A. Amin","doi":"10.1080/21548331.2016.1258292","DOIUrl":"https://doi.org/10.1080/21548331.2016.1258292","url":null,"abstract":"ABSTRACT Cryptogenic strokes are responsible for significant morbidity and mortality. Identifying the underlying cause of cryptogenic stroke is imperative for appropriate short and long-term management of these patients. In particular, detecting atrial fibrillation in cryptogenic stroke patients may shed insight into the cause of the index stroke, but is also important to identify an important cause of secondary stroke. There is accumulating evidence indicating that monitoring for durations beyond the guideline recommended 30 day-period results in greater atrial fibrillation yield. This article reviews current guidelines and practices for the diagnosis of cryptogenic stroke, as well as outpatient cardiac monitoring options available, and focuses on the role that hospitalists have to play in the care of these patients.","PeriodicalId":75913,"journal":{"name":"Hospital practice","volume":"44 1","pages":"274 - 278"},"PeriodicalIF":0.0,"publicationDate":"2016-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.2016.1258292","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60073988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lean intervention improves patient discharge times, improves emergency department throughput and reduces congestion 精益干预改善了病人出院时间,提高了急诊科的吞吐量,减少了拥堵
Pub Date : 2016-10-19 DOI: 10.1080/21548331.2016.1254559
M. Beck, Davin Okerblom, Anika Kumar, S. Bandyopadhyay, L. Scalzi
ABSTRACT Objective: To determine if a lean intervention improved emergency department (ED) throughput and reduced ED boarding by improving patient discharge efficiency from a tertiary care children’s hospital. Methods: The study was conducted at a tertiary care children’s hospital to study the impact lean that changes made to an inpatient pediatric service line had on ED efficiency. Discharge times from the general pediatrics’ service were compared to patients discharged from all other pediatric subspecialty services. The intervention was multifaceted. First, team staffing reconfiguration permitted all discharge work to be done at the patient’s bedside using a new discharge checklist. The intervention also incorporated an afternoon interdisciplinary huddle to work on the following day’s discharges. Retrospectively, we determined the impact this had on median times of discharge order entry, patient discharge, and percent of patients discharged before noon. As a marker of ED throughput, we determined median hour of day that admitted patients left the ED to move to their hospital bed. As marker of ED congestion we determined median boarding times. Results: For the general pediatrics service line, the median discharge order entry time decreased from 1:43pm to 11:28am (p < 0.0001) and the median time of discharge decreased from 3:25pm to 2:25pm (p < 0.0001). The percent of patients discharged before noon increased from 14.0% to 26.0% (p < 0.0001). The discharge metrics remained unchanged for the pediatric subspecialty services group. Median ED boarding time decreased by 49 minutes (p < 0.0001). As a result, the median time of day admitted patients were discharged from the ED was advanced from 5 PM to 4 PM. Conclusion: Lean principles implemented by one hospital service line improved patient discharge times enhanced patient ED throughput, and reduced ED boarding times.
目的:探讨精益干预是否能通过提高三级儿童医院的病人出院效率来提高急诊科(ED)的吞吐量并减少ED登院率。方法:本研究在一家三级儿童医院进行,研究儿科住院服务线的改变对急诊科效率的影响。将普通儿科服务的出院时间与所有其他儿科亚专科服务的出院时间进行比较。干预是多方面的。首先,团队人员配置重组允许所有出院工作在患者床边完成,使用新的出院清单。干预还包括一个下午的跨学科会议,以解决第二天的出院问题。回顾性地,我们确定了这对出院单输入的中位数时间、患者出院时间和中午前出院患者百分比的影响。作为急诊科吞吐量的标志,我们确定了入院患者离开急诊科搬到医院病床上的平均时间。作为急诊科拥堵的标志,我们确定了中位数登机时间。结果:在普通儿科服务线,出院单录入时间中位数从1:43pm下降到11:28am (p < 0.0001),出院时间中位数从3:25pm下降到2:25pm (p < 0.0001)。中午前出院的患者比例由14.0%上升至26.0% (p < 0.0001)。儿科亚专科服务组的出院指标保持不变。ED登机时间中位数减少了49分钟(p < 0.0001)。结果,入院患者从急诊科出院的平均时间从下午5点提前到下午4点。结论:一家医院服务线实施的精益原则改善了病人出院时间,提高了急诊科病人吞吐量,减少了急诊科住院时间。
{"title":"Lean intervention improves patient discharge times, improves emergency department throughput and reduces congestion","authors":"M. Beck, Davin Okerblom, Anika Kumar, S. Bandyopadhyay, L. Scalzi","doi":"10.1080/21548331.2016.1254559","DOIUrl":"https://doi.org/10.1080/21548331.2016.1254559","url":null,"abstract":"ABSTRACT Objective: To determine if a lean intervention improved emergency department (ED) throughput and reduced ED boarding by improving patient discharge efficiency from a tertiary care children’s hospital. Methods: The study was conducted at a tertiary care children’s hospital to study the impact lean that changes made to an inpatient pediatric service line had on ED efficiency. Discharge times from the general pediatrics’ service were compared to patients discharged from all other pediatric subspecialty services. The intervention was multifaceted. First, team staffing reconfiguration permitted all discharge work to be done at the patient’s bedside using a new discharge checklist. The intervention also incorporated an afternoon interdisciplinary huddle to work on the following day’s discharges. Retrospectively, we determined the impact this had on median times of discharge order entry, patient discharge, and percent of patients discharged before noon. As a marker of ED throughput, we determined median hour of day that admitted patients left the ED to move to their hospital bed. As marker of ED congestion we determined median boarding times. Results: For the general pediatrics service line, the median discharge order entry time decreased from 1:43pm to 11:28am (p < 0.0001) and the median time of discharge decreased from 3:25pm to 2:25pm (p < 0.0001). The percent of patients discharged before noon increased from 14.0% to 26.0% (p < 0.0001). The discharge metrics remained unchanged for the pediatric subspecialty services group. Median ED boarding time decreased by 49 minutes (p < 0.0001). As a result, the median time of day admitted patients were discharged from the ED was advanced from 5 PM to 4 PM. Conclusion: Lean principles implemented by one hospital service line improved patient discharge times enhanced patient ED throughput, and reduced ED boarding times.","PeriodicalId":75913,"journal":{"name":"Hospital practice","volume":"44 1","pages":"252 - 259"},"PeriodicalIF":0.0,"publicationDate":"2016-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.2016.1254559","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60073502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 45
Hemorrhagic bullous dermatosis: a rare heparin-induced cutaneous manifestation 出血性大疱性皮肤病:一种罕见的肝素引起的皮肤表现
Pub Date : 2016-03-14 DOI: 10.1080/21548331.2016.1159908
Bhuvanesh Govind, E. Gnass, G. Merli, L. Eraso
ABSTRACT Heparin is one of the most widely prescribed medications. Cutaneous reactions distant to the injection site are rare and under-reported in the literature. We present an elderly man with history of CNS lymphoma who underwent treatment of a deep venous thrombosis with enoxaparin and subsequently developed well demarcated bullous lesions within days of heparin initiation. The exact pathophysiology is not well understood. Hemorrhagic bullous dermatosis is a rare cutaneous reaction that is temporally associated with the initiation of heparin products. The handful of cases thus far suggest that regression of these seemingly benign lesions may or may not be associated with dose reduction or discontinuation of heparin products and typically occur within a few weeks. Elderly age appears to be one potential risk factor for development of these rare asymptomatic lesions. Malignancy may have some contributing factor and differentiation between this rare cutaneous manifestation from heparin products and other dermatological findings in patients with malignancy is key. Because of the asymptomatic and self-limiting nature of hemorrhagic bullous dermatoses in the setting of heparin product use, we presume that the reported incidence does not reflect true clinical practice.
肝素是处方最广泛的药物之一。远离注射部位的皮肤反应是罕见的,文献报道不足。我们报告了一位有中枢神经系统淋巴瘤病史的老年男性,他接受了依诺肝素治疗深静脉血栓形成,随后在肝素开始治疗的几天内出现了界限清晰的大泡性病变。确切的病理生理机制尚不清楚。出血性大疱性皮肤病是一种罕见的皮肤反应,暂时与肝素产品的开始有关。迄今为止的少数病例表明,这些看似良性的病变的消退可能与减少剂量或停止肝素产品有关,也可能与之无关,并且通常在几周内发生。老年似乎是发展这些罕见的无症状病变的一个潜在的危险因素。恶性肿瘤可能有一些促成因素,区分肝素产品的这种罕见皮肤表现与恶性肿瘤患者的其他皮肤病学表现是关键。由于出血性大疱性皮肤病在使用肝素产品的情况下无症状和自限性,我们认为报道的发病率并不能反映真实的临床实践。
{"title":"Hemorrhagic bullous dermatosis: a rare heparin-induced cutaneous manifestation","authors":"Bhuvanesh Govind, E. Gnass, G. Merli, L. Eraso","doi":"10.1080/21548331.2016.1159908","DOIUrl":"https://doi.org/10.1080/21548331.2016.1159908","url":null,"abstract":"ABSTRACT Heparin is one of the most widely prescribed medications. Cutaneous reactions distant to the injection site are rare and under-reported in the literature. We present an elderly man with history of CNS lymphoma who underwent treatment of a deep venous thrombosis with enoxaparin and subsequently developed well demarcated bullous lesions within days of heparin initiation. The exact pathophysiology is not well understood. Hemorrhagic bullous dermatosis is a rare cutaneous reaction that is temporally associated with the initiation of heparin products. The handful of cases thus far suggest that regression of these seemingly benign lesions may or may not be associated with dose reduction or discontinuation of heparin products and typically occur within a few weeks. Elderly age appears to be one potential risk factor for development of these rare asymptomatic lesions. Malignancy may have some contributing factor and differentiation between this rare cutaneous manifestation from heparin products and other dermatological findings in patients with malignancy is key. Because of the asymptomatic and self-limiting nature of hemorrhagic bullous dermatoses in the setting of heparin product use, we presume that the reported incidence does not reflect true clinical practice.","PeriodicalId":75913,"journal":{"name":"Hospital practice","volume":"27 1","pages":"103 - 107"},"PeriodicalIF":0.0,"publicationDate":"2016-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.2016.1159908","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60073286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Telehealth for patients with Parkinson’s disease: delivering efficient and sustainable long-term care 帕金森病患者的远程保健:提供有效和可持续的长期护理
Pub Date : 2016-03-14 DOI: 10.1080/21548331.2016.1166922
P. Barbour, Jill Arroyo, Star High, Lisa B Fichera, Marie M Staska-Pier, Mary Kay McMahon
ABSTRACT Objectives: We set out to demonstrate the benefits of providing long-term care via telehealth for patients with Parkinson’s disease living in continuous care facilities. Methods: A cohort of 16 patients with Parkinson’s disease residing at one of 2 locations of a multi-facility continuous care retirement organization were seen virtually in follow-up over a 3-year period by Telehealth Services at a large, academic, tertiary care hospital in southeastern Pennsylvania. The data collected during that period, studied retrospectively, included demographic information, number of telehealth visits, and UPDRS scores obtained at each visit. Satisfaction and potential cost savings were also reviewed. Results: UPDRS scores declined over the period of observation, from a range of 18-60 at study start to 28-72 at study end. Actual cost savings are difficult to define; however, the cost per telehealth visit at $117.30 was often lower than the facility’s average cost for transporting patients to a visit in the neurologist’s office. Patients, families, subspecialists, and the nursing staff expressed uniformly high satisfaction with telehealth. Conclusion: This model for providing care proved to be sustainable and efficient, and promoted collaboration among the providers at the long-term care facility and those at the remote site. These benefits may be applicable to patients with degenerative disorders in similar settings.
目的:我们着手证明通过远程医疗为生活在连续护理机构中的帕金森病患者提供长期护理的好处。方法:在宾夕法尼亚州东南部的一家大型学术三级医院的远程医疗服务中,对居住在多设施连续护理退休组织的2个地点之一的16名帕金森病患者进行了为期3年的虚拟随访。回顾性研究了在此期间收集的数据,包括人口统计信息、远程医疗就诊次数和每次就诊时获得的UPDRS得分。还审查了满意度和潜在的成本节约。结果:UPDRS评分在观察期间有所下降,从研究开始时的18-60分下降到研究结束时的28-72分。实际的成本节约很难定义;然而,每次远程医疗访问的费用为117.30美元,通常低于该设施运送患者到神经科医生办公室访问的平均费用。患者、家属、专科医生和护理人员一致对远程医疗表示高度满意。结论:这种提供护理的模式被证明是可持续和高效的,并促进了长期护理机构和远程站点提供者之间的合作。这些益处可能适用于类似情况下的退行性疾病患者。
{"title":"Telehealth for patients with Parkinson’s disease: delivering efficient and sustainable long-term care","authors":"P. Barbour, Jill Arroyo, Star High, Lisa B Fichera, Marie M Staska-Pier, Mary Kay McMahon","doi":"10.1080/21548331.2016.1166922","DOIUrl":"https://doi.org/10.1080/21548331.2016.1166922","url":null,"abstract":"ABSTRACT Objectives: We set out to demonstrate the benefits of providing long-term care via telehealth for patients with Parkinson’s disease living in continuous care facilities. Methods: A cohort of 16 patients with Parkinson’s disease residing at one of 2 locations of a multi-facility continuous care retirement organization were seen virtually in follow-up over a 3-year period by Telehealth Services at a large, academic, tertiary care hospital in southeastern Pennsylvania. The data collected during that period, studied retrospectively, included demographic information, number of telehealth visits, and UPDRS scores obtained at each visit. Satisfaction and potential cost savings were also reviewed. Results: UPDRS scores declined over the period of observation, from a range of 18-60 at study start to 28-72 at study end. Actual cost savings are difficult to define; however, the cost per telehealth visit at $117.30 was often lower than the facility’s average cost for transporting patients to a visit in the neurologist’s office. Patients, families, subspecialists, and the nursing staff expressed uniformly high satisfaction with telehealth. Conclusion: This model for providing care proved to be sustainable and efficient, and promoted collaboration among the providers at the long-term care facility and those at the remote site. These benefits may be applicable to patients with degenerative disorders in similar settings.","PeriodicalId":75913,"journal":{"name":"Hospital practice","volume":"44 1","pages":"92 - 97"},"PeriodicalIF":0.0,"publicationDate":"2016-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.2016.1166922","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60073482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
Hospitalists’ utilization of weight loss resources with discharge texts and primary care contact: a feasibility study 医院医生利用出院短信和初级保健联系减肥资源的可行性研究
Pub Date : 2016-03-02 DOI: 10.1080/21548331.2016.1155396
C. Harris, L. Cheskin, W. Khaliq, Denis G. Antoine, R. Landis, Emma M. Steinberg, S. Wright
ABSTRACT Objectives: Obesity affects a large proportion of the U.S. population, and hospitalizations may serve as an opportunity to promote weight loss. We sought to determine if multidisciplinary patient-centered inpatient weight loss intervention that included counseling, consults, post-discharge telephone text messages, and primary care follow up was feasible. Methods: We conducted a feasibility study focusing on 25 obese hospitalized patients to understand the issues related to rolling out an intensive intervention. Actual weight loss was a secondary outcome and we compared these 25 patients to 28 control patients who were exposed to usual care; weight change was assessed at 1 and 6 months. Results: Ninety-six percent (24/25) of nutritional consults and 92% (23/25) of physical therapy consults were submitted by hospital providers. All of these doctors were also reminded to counsel their patients about the detrimental health consequences. Fifty-two percent (13/25) and 40% (10/25) were actually seen and counseled by nutrition and physical therapy services respectively, before being discharged. Sixty-eight percent (17/25) received a motivational interviewing counseling session from the principal investigator. All patients were sent text messages and followed with their primary care provider after discharge who received the personalized weight loss discharge instructions that had been given to the patient. The feasibility group lost a mean of 3.0 kg at 6 months and the control group gained an average of 0.20 kg at 6 months post discharge (p = 0.03). Conclusion: Executing a multifaceted weight loss intervention for hospitalized obese patients is feasible, and there may be associated persistent improvements in weight status over time.
【摘要】目的:肥胖影响了很大一部分美国人口,住院治疗可能是促进减肥的一个机会。我们试图确定多学科的以患者为中心的住院患者减肥干预,包括咨询、会诊、出院后电话短信和初级保健随访是否可行。方法:我们对25例肥胖住院患者进行了可行性研究,以了解开展强化干预的相关问题。实际体重减轻是次要结果,我们将这25名患者与28名接受常规护理的对照患者进行比较;在1个月和6个月时评估体重变化。结果:96%(24/25)的营养咨询和92%(23/25)的物理治疗咨询由医院提供者提交。所有这些医生还被提醒要就有害健康的后果向病人提出咨询。52%(13/25)和40%(10/25)的患者在出院前分别接受了营养和物理治疗服务的咨询。68%(17/25)接受了主要研究者的动机性访谈咨询。所有患者都收到了短信,出院后,他们的初级保健提供者收到了发给患者的个性化减肥出院指示。可行性组患者出院后6个月平均体重减轻3.0 kg,对照组患者出院后6个月平均体重增加0.20 kg (p = 0.03)。结论:对住院肥胖患者实施多方面的减肥干预是可行的,并且随着时间的推移,体重状况可能会有持续的改善。
{"title":"Hospitalists’ utilization of weight loss resources with discharge texts and primary care contact: a feasibility study","authors":"C. Harris, L. Cheskin, W. Khaliq, Denis G. Antoine, R. Landis, Emma M. Steinberg, S. Wright","doi":"10.1080/21548331.2016.1155396","DOIUrl":"https://doi.org/10.1080/21548331.2016.1155396","url":null,"abstract":"ABSTRACT Objectives: Obesity affects a large proportion of the U.S. population, and hospitalizations may serve as an opportunity to promote weight loss. We sought to determine if multidisciplinary patient-centered inpatient weight loss intervention that included counseling, consults, post-discharge telephone text messages, and primary care follow up was feasible. Methods: We conducted a feasibility study focusing on 25 obese hospitalized patients to understand the issues related to rolling out an intensive intervention. Actual weight loss was a secondary outcome and we compared these 25 patients to 28 control patients who were exposed to usual care; weight change was assessed at 1 and 6 months. Results: Ninety-six percent (24/25) of nutritional consults and 92% (23/25) of physical therapy consults were submitted by hospital providers. All of these doctors were also reminded to counsel their patients about the detrimental health consequences. Fifty-two percent (13/25) and 40% (10/25) were actually seen and counseled by nutrition and physical therapy services respectively, before being discharged. Sixty-eight percent (17/25) received a motivational interviewing counseling session from the principal investigator. All patients were sent text messages and followed with their primary care provider after discharge who received the personalized weight loss discharge instructions that had been given to the patient. The feasibility group lost a mean of 3.0 kg at 6 months and the control group gained an average of 0.20 kg at 6 months post discharge (p = 0.03). Conclusion: Executing a multifaceted weight loss intervention for hospitalized obese patients is feasible, and there may be associated persistent improvements in weight status over time.","PeriodicalId":75913,"journal":{"name":"Hospital practice","volume":"44 1","pages":"102 - 98"},"PeriodicalIF":0.0,"publicationDate":"2016-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.2016.1155396","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60073155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Increasing patient knowledge on the proper usage of a PCA machine with the use of a post-operative instructional card 通过使用术后指导卡,增加患者对PCA机器正确使用的知识
Pub Date : 2016-02-29 DOI: 10.1080/21548331.2016.1149015
L. Shovel, Bryan Max, D. Correll
ABSTRACT Objectives: The purpose of this study was to see if an instructional card, attached to the PCA machine following total hip arthroplasty describing proper use of the device, would positively affect subjects’ understanding of device usage, pain scores, pain medication consumption and satisfaction. Methods: Eighty adults undergoing total hip replacements who had been prescribed PCA were randomized into two study groups. Forty participants received the standard post-operative instruction on PCA device usage at our institution. The other 40 participants received the standard of care in addition to being given a typed instructional card immediately post-operatively, describing proper PCA device use. This card was attached to the PCA device during their recovery period. On post-operative day one, each patient completed a questionnaire on PCA usage, pain scores and satisfaction scores. Results: The pain scores in the Instructional Card group were significantly lower than the Control group (p = 0.024). Subjects’ understanding of PCA usage was also improved in the Instructional Card group for six of the seven questions asked. Conclusion: The findings from this study strongly support that postoperative patient information on proper PCA use by means of an instructional card improves pain control and hence the overall recovery for patients undergoing surgery. In addition, through improved understanding it adds an important safety feature in that patients and potentially their family members and/or friends may refrain from PCA-by-proxy. This article demonstrates that the simple intervention of adding an instructional card to a PCA machine is an effective method to improve patients’ knowledge as well as pain control and potentially increase the safety of the device use.
摘要目的:本研究的目的是观察全髋关节置换术后,在PCA机器上贴一张描述设备正确使用的指导卡,是否会积极影响受试者对设备使用、疼痛评分、止痛药使用和满意度的理解。方法:80名接受全髋关节置换术的成年人被随机分为两个研究组。40名参与者在我院接受了有关PCA器械使用的标准术后指导。其他40名参与者接受标准护理,并在术后立即给予打字指导卡,描述正确的PCA设备使用。这张卡是在他们恢复期间连接到PCA设备。术后第一天,每位患者完成PCA使用问卷、疼痛评分和满意度评分。结果:教学卡组疼痛评分显著低于对照组(p = 0.024)。在七个问题中的六个问题上,教学卡组的受试者对PCA用法的理解也有所提高。结论:本研究的结果有力地支持了术后患者通过指导卡正确使用PCA的信息可以改善疼痛控制,从而改善手术患者的整体恢复。此外,通过更好的理解,它增加了一个重要的安全特征,即患者及其潜在的家庭成员和/或朋友可能会避免使用PCA-by-proxy。本文表明,在PCA机器中添加指导卡的简单干预是一种有效的方法,可以提高患者的知识和疼痛控制,并可能增加设备使用的安全性。
{"title":"Increasing patient knowledge on the proper usage of a PCA machine with the use of a post-operative instructional card","authors":"L. Shovel, Bryan Max, D. Correll","doi":"10.1080/21548331.2016.1149015","DOIUrl":"https://doi.org/10.1080/21548331.2016.1149015","url":null,"abstract":"ABSTRACT Objectives: The purpose of this study was to see if an instructional card, attached to the PCA machine following total hip arthroplasty describing proper use of the device, would positively affect subjects’ understanding of device usage, pain scores, pain medication consumption and satisfaction. Methods: Eighty adults undergoing total hip replacements who had been prescribed PCA were randomized into two study groups. Forty participants received the standard post-operative instruction on PCA device usage at our institution. The other 40 participants received the standard of care in addition to being given a typed instructional card immediately post-operatively, describing proper PCA device use. This card was attached to the PCA device during their recovery period. On post-operative day one, each patient completed a questionnaire on PCA usage, pain scores and satisfaction scores. Results: The pain scores in the Instructional Card group were significantly lower than the Control group (p = 0.024). Subjects’ understanding of PCA usage was also improved in the Instructional Card group for six of the seven questions asked. Conclusion: The findings from this study strongly support that postoperative patient information on proper PCA use by means of an instructional card improves pain control and hence the overall recovery for patients undergoing surgery. In addition, through improved understanding it adds an important safety feature in that patients and potentially their family members and/or friends may refrain from PCA-by-proxy. This article demonstrates that the simple intervention of adding an instructional card to a PCA machine is an effective method to improve patients’ knowledge as well as pain control and potentially increase the safety of the device use.","PeriodicalId":75913,"journal":{"name":"Hospital practice","volume":"44 1","pages":"71 - 75"},"PeriodicalIF":0.0,"publicationDate":"2016-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.2016.1149015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60072793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Assessment of the appropriateness of naloxone administration to patients receiving long-term opioid therapy 对接受长期阿片类药物治疗的患者给予纳洛酮的适宜性评估
Pub Date : 2016-02-22 DOI: 10.1080/21548331.2016.1149016
Caroline Facey, D. Brooks, J. Boland
ABSTRACT Background: The most dangerous adverse effect of opioids is respiratory depression. Naloxone is used to reverse this, although in patients receiving long-term opioid therapy it can cause acute opioid withdrawal and opioid-refractory pain. Objective: To determine if naloxone is appropriately administered to patients receiving long-term opioid therapy. Methods: This retrospective case series based on chart reviews systematically identified patients over one year in a district general hospital. All patients aged 18 years or older receiving long-term opioid therapy admitted to medicine, surgery or the high dependency unit who were administered naloxone during their admission were included. Results: A total of 1206 patient drug administration records were reviewed. Sixteen patients receiving long-term opioid therapy were administered naloxone. Twelve of these did not have opioid-induced respiratory depression and four did not have respiratory rate and oxygen saturations documented in the medical notes. All naloxone doses administered were higher than those recommended by national guidelines for this patient group. Conclusions: No patient receiving long-term opioid therapy who was administered naloxone had evidence of respiratory depression. More thorough assessment and documentation are needed. Verbal and physical stimulation as well as oxygenation should be considered prior to naloxone administration; this should be followed by close observation, hydration, renal function tests and opioid dose review.
背景:阿片类药物最危险的不良反应是呼吸抑制。纳洛酮用于逆转这种情况,尽管在接受长期阿片类药物治疗的患者中,它可能导致急性阿片类药物戒断和阿片类药物难治性疼痛。目的:确定纳洛酮是否适用于接受长期阿片类药物治疗的患者。方法:采用回顾性病例分析方法,对某地区综合医院住院1年以上的患者进行系统分析。所有接受长期阿片类药物治疗的18岁或以上的患者在入院期间接受纳洛酮治疗,包括药物、手术或高依赖病房。结果:共审查1206例患者用药记录。16例接受长期阿片类药物治疗的患者给予纳洛酮治疗。其中12人没有阿片类药物引起的呼吸抑制,4人没有医疗记录中记录的呼吸速率和氧饱和度。所有给予的纳洛酮剂量都高于国家指南对该患者组的推荐剂量。结论:接受长期阿片类药物治疗并给予纳洛酮的患者没有呼吸抑制的证据。需要更彻底的评估和文档。服用纳洛酮前应考虑言语和身体刺激以及氧合;随后应进行密切观察、水合作用、肾功能检查和阿片类药物剂量审查。
{"title":"Assessment of the appropriateness of naloxone administration to patients receiving long-term opioid therapy","authors":"Caroline Facey, D. Brooks, J. Boland","doi":"10.1080/21548331.2016.1149016","DOIUrl":"https://doi.org/10.1080/21548331.2016.1149016","url":null,"abstract":"ABSTRACT Background: The most dangerous adverse effect of opioids is respiratory depression. Naloxone is used to reverse this, although in patients receiving long-term opioid therapy it can cause acute opioid withdrawal and opioid-refractory pain. Objective: To determine if naloxone is appropriately administered to patients receiving long-term opioid therapy. Methods: This retrospective case series based on chart reviews systematically identified patients over one year in a district general hospital. All patients aged 18 years or older receiving long-term opioid therapy admitted to medicine, surgery or the high dependency unit who were administered naloxone during their admission were included. Results: A total of 1206 patient drug administration records were reviewed. Sixteen patients receiving long-term opioid therapy were administered naloxone. Twelve of these did not have opioid-induced respiratory depression and four did not have respiratory rate and oxygen saturations documented in the medical notes. All naloxone doses administered were higher than those recommended by national guidelines for this patient group. Conclusions: No patient receiving long-term opioid therapy who was administered naloxone had evidence of respiratory depression. More thorough assessment and documentation are needed. Verbal and physical stimulation as well as oxygenation should be considered prior to naloxone administration; this should be followed by close observation, hydration, renal function tests and opioid dose review.","PeriodicalId":75913,"journal":{"name":"Hospital practice","volume":"44 1","pages":"86 - 91"},"PeriodicalIF":0.0,"publicationDate":"2016-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.2016.1149016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60072937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Hospital practice
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1