{"title":"Cellular and molecular mechanisms of intracellular symbiosis in leishmaniasis.","authors":"K P Chang","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75946,"journal":{"name":"International review of cytology. Supplement","volume":"14 ","pages":"267-305"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17401754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1983-01-01DOI: 10.1016/b978-0-12-364376-6.50011-9
J M Lord, L M Roberts
{"title":"Formation of glyoxysomes.","authors":"J M Lord, L M Roberts","doi":"10.1016/b978-0-12-364376-6.50011-9","DOIUrl":"https://doi.org/10.1016/b978-0-12-364376-6.50011-9","url":null,"abstract":"","PeriodicalId":75946,"journal":{"name":"International review of cytology. Supplement","volume":"15 ","pages":"115-56"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17403470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aspects of cell regulation.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75946,"journal":{"name":"International review of cytology. Supplement","volume":"15 ","pages":"1-283"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17630790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1983-01-01DOI: 10.1016/b978-0-12-364376-6.50007-7
R W Harrison
Virtually all glucocorticoid effects are mediated through changes in gene transcription. Steroid binding to the receptor and nuclear binding of the steroid-receptor complex are pivotal events in this process, but may be modified by the ability of a given steroid to traverse the cell membrane or cause receptor activation. The physical nature of the receptor, its precise subcellular location, and the process by which gene activation is accomplished are unknown. Preparation of purified receptor and further characterization of the nuclear binding sites will be crucial to a better understanding of this process.
{"title":"Cellular factors which modulate hormone responses: glucocorticoid action in perspective.","authors":"R W Harrison","doi":"10.1016/b978-0-12-364376-6.50007-7","DOIUrl":"https://doi.org/10.1016/b978-0-12-364376-6.50007-7","url":null,"abstract":"<p><p>Virtually all glucocorticoid effects are mediated through changes in gene transcription. Steroid binding to the receptor and nuclear binding of the steroid-receptor complex are pivotal events in this process, but may be modified by the ability of a given steroid to traverse the cell membrane or cause receptor activation. The physical nature of the receptor, its precise subcellular location, and the process by which gene activation is accomplished are unknown. Preparation of purified receptor and further characterization of the nuclear binding sites will be crucial to a better understanding of this process.</p>","PeriodicalId":75946,"journal":{"name":"International review of cytology. Supplement","volume":"15 ","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17403469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1983-01-01DOI: 10.1016/b978-0-12-364376-6.50013-2
R A Weinberg
{"title":"Transforming genes of tumor cells.","authors":"R A Weinberg","doi":"10.1016/b978-0-12-364376-6.50013-2","DOIUrl":"https://doi.org/10.1016/b978-0-12-364376-6.50013-2","url":null,"abstract":"","PeriodicalId":75946,"journal":{"name":"International review of cytology. Supplement","volume":"15 ","pages":"191-202"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17403385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1983-01-01DOI: 10.1016/b978-0-12-364376-6.50009-0
C W Birky
When an organism has only one or two mitochondria or chloroplasts per cell, it is probable that their partitioning is always stringently controlled so that each daughter cell always receives half the organelles in the parent cell. When there are more copies of an organelle, the available data suggest that partitioning is stochastic but far from random, with a strong tendency toward equality. The molecular mechanisms that promote equal partitioning are not known in any case, but the great variety of organelle behavior suggests that many different mechanisms are involved in different organisms. As Wilson (1925) pointed out, the precision of partitioning of cytoplasmic organelles rarely if ever equals that of mitosis, but it is still an expression of selection for mechanisms that will ensure the hereditary continuity of the organelles. How cells compensate for unequal partitioning by controlling organelle replication is known for only one case. But when one considers that Tetrahymena and Paramecium use different methods to compensate for unequal partitioning of macronuclear DNA, it would not be surprising if organisms use a variety of different compensating replication modes for organelles as well. What is surprising is that so little attention has been paid to these problems. Nothing could be simpler than counting organelles in dividing cells, but this has been done on a large scale in only two systems. Quantitative techniques in cell biology have been developed to the point where such studies could be done even on cells that have too many organelles for direct counting. Molecular mechanisms of partitioning have scarcely been touched on. Much more has been done on the role of the cytoskeleton in determining cell shape, and some observations have been made on its role in positioning organelles in interphase cells, but these kinds of studies have not been extended to dividing cells. Some experiments and observations have been made on the role of microtubules and microfilaments in moving cytoplasmic organelles around the cell during interphase, but again nothing has been done on their possible role in partitioning organelles at cytokinesis. The major lesson of this article is how little has been done, and how much can be done. The partitioning of cytoplasmic organelles at cell division is a wide-open field for future research, and one of great importance for both genetics and cell biology.
{"title":"The partitioning of cytoplasmic organelles at cell division.","authors":"C W Birky","doi":"10.1016/b978-0-12-364376-6.50009-0","DOIUrl":"https://doi.org/10.1016/b978-0-12-364376-6.50009-0","url":null,"abstract":"<p><p>When an organism has only one or two mitochondria or chloroplasts per cell, it is probable that their partitioning is always stringently controlled so that each daughter cell always receives half the organelles in the parent cell. When there are more copies of an organelle, the available data suggest that partitioning is stochastic but far from random, with a strong tendency toward equality. The molecular mechanisms that promote equal partitioning are not known in any case, but the great variety of organelle behavior suggests that many different mechanisms are involved in different organisms. As Wilson (1925) pointed out, the precision of partitioning of cytoplasmic organelles rarely if ever equals that of mitosis, but it is still an expression of selection for mechanisms that will ensure the hereditary continuity of the organelles. How cells compensate for unequal partitioning by controlling organelle replication is known for only one case. But when one considers that Tetrahymena and Paramecium use different methods to compensate for unequal partitioning of macronuclear DNA, it would not be surprising if organisms use a variety of different compensating replication modes for organelles as well. What is surprising is that so little attention has been paid to these problems. Nothing could be simpler than counting organelles in dividing cells, but this has been done on a large scale in only two systems. Quantitative techniques in cell biology have been developed to the point where such studies could be done even on cells that have too many organelles for direct counting. Molecular mechanisms of partitioning have scarcely been touched on. Much more has been done on the role of the cytoskeleton in determining cell shape, and some observations have been made on its role in positioning organelles in interphase cells, but these kinds of studies have not been extended to dividing cells. Some experiments and observations have been made on the role of microtubules and microfilaments in moving cytoplasmic organelles around the cell during interphase, but again nothing has been done on their possible role in partitioning organelles at cytokinesis. The major lesson of this article is how little has been done, and how much can be done. The partitioning of cytoplasmic organelles at cell division is a wide-open field for future research, and one of great importance for both genetics and cell biology.</p>","PeriodicalId":75946,"journal":{"name":"International review of cytology. Supplement","volume":"15 ","pages":"49-89"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/b978-0-12-364376-6.50009-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17403386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1983-01-01DOI: 10.1016/b978-0-12-364376-6.50008-9
A Abdukarimov
{"title":"Regulation of genetic activity by thyroid hormones.","authors":"A Abdukarimov","doi":"10.1016/b978-0-12-364376-6.50008-9","DOIUrl":"https://doi.org/10.1016/b978-0-12-364376-6.50008-9","url":null,"abstract":"","PeriodicalId":75946,"journal":{"name":"International review of cytology. Supplement","volume":"15 ","pages":"17-48"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17254232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1983-01-01DOI: 10.1016/b978-0-12-364376-6.50015-6
R E Matthews
{"title":"The origin of viruses from cells.","authors":"R E Matthews","doi":"10.1016/b978-0-12-364376-6.50015-6","DOIUrl":"https://doi.org/10.1016/b978-0-12-364376-6.50015-6","url":null,"abstract":"","PeriodicalId":75946,"journal":{"name":"International review of cytology. Supplement","volume":"15 ","pages":"245-80"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17365634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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