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Modified MacLaughlin procedure in the treatment of neglected posterior dislocation of the shoulder. 改良麦克劳克林手术治疗被忽视的肩后脱位。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0001-y
Alessandro Castagna, Giacomo Delle Rose, Mario Borroni, Nikolaos Markopoulos, Marco Conti, Leonardo Maradei, Raffaele Garofalo

Posterior dislocation of the shoulder is an unusual injury that most often occurs secondary to a high-energy trauma. Unfortunately the diagnosis is commonly missed, thus making its treatment a challenge. Neglected posterior dislocation is mainly characterised by an impression fracture on the anterior articular surface of the humeral head, which makes the dislocation often difficult to reduce. Diagnosis is based upon a careful history assessment, physical examination and radiological findings. Several treatment approaches have been described. The modified MacLaughlin procedure in our hands has been shown to be a reproducible technique allowing good results at medium- and long-term follow-up. According to our experience it is possible to adopt this technique also in patients with a locked posterior dislocation older than 6 months or in cases with a humeral head defect up to 50% when a shoulder prosthesis is not a good indication. Poorer results should be expected in patients with an associated fracture of the proximal humerus.

肩后脱位是一种罕见的损伤,通常发生在高能量创伤后。不幸的是,诊断通常被遗漏,因此使其治疗成为一个挑战。被忽视的后路脱位主要表现为肱骨头前关节面印痕骨折,这使得脱位通常难以复位。诊断是基于仔细的病史评估,体格检查和放射检查结果。已经描述了几种治疗方法。我们手上改良的麦克劳克林手术已被证明是一种可重复的技术,在中期和长期随访中可以获得良好的结果。根据我们的经验,对于年龄大于6个月的后路锁定脱位患者,或者肩关节假体不适合时肱骨头缺损达50%的患者,也可以采用该技术。伴有肱骨近端骨折的患者预后较差。
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引用次数: 34
Humeral shaft aseptic nonunion: treatment with opposite cortical allograft struts. 肱骨干无菌性骨不连:对侧皮质同种异体支架治疗。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0007-5
Alessandro Marinelli, Diego Antonioli, Enrico Guerra, Graziano Bettelli, Lorenzo Zaccarelli, Roberto Rotini

Plate fixation with cortical allograft struts has been used at our Institute for decades to treat aseptic shaft nonunion. The aim of this study was to assess the results of this technique in humeral nonunion. We retrospectively reviewed 57 consecutive patients with humeral diaphyseal nonunion treated by internal fixation combined with cortical allograft struts in the last 7 years in our Department. The patients were followed-up for a mean of 48 months. We had union in 53 cases out of 57. There were 3 cases of infection out of 15 patients previously treated with an external fixator. In our experience the cortical allograft strut is a well standardised and reproducible technique that enables the treatment of severe atrophic non-union with a relatively low complication rate and quick functional recovery.

皮质同种异体支架钢板固定在我所治疗无菌性骨不连已有几十年的历史。本研究的目的是评估该技术在肱骨不愈合中的效果。我们回顾性分析了过去7年来本科连续57例肱骨骨干骨不连采用内固定联合皮质异体支架治疗的病例。随访时间平均为48个月。57例中有53例愈合。15例患者中有3例感染,既往使用外固定架治疗。根据我们的经验,皮质同种异体移植支架是一种标准化和可重复的技术,可以治疗严重萎缩性骨不连,并发症发生率相对较低,功能恢复较快。
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引用次数: 18
Reverse shoulder prosthesis as revision surgery after fractures of the proximal humerus, treated initially by internal fixation or hemiarthroplasty. 肱骨近端骨折后行反向肩关节假体翻修手术,最初采用内固定或半关节置换术治疗。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0006-6
Nicola Lollino, Paolo Paladini, Fabrizio Campi, Giovanni Merolla, Paolo Rossi, Giuseppe Porcellini

Complex (3-4 fragments) fractures of the proximal humerus often have a bad outcome, whatever treatment is performed. When revision surgery is required, reverse shoulder prosthesis can improve function and reduce pain in these patients. We analysed whether the choice of the first treatment (hemiarthroplasty vs. reduction and fixation) can influence the outcome of revision surgery. Our data demonstrate that results are not significantly dependent on the choice of the first implant, even though there is a tendency for patients with previous hemiarthroplasty to have a worse outcome.

肱骨近端复杂骨折(3-4块骨折),无论采用何种治疗方法,往往预后不佳。当需要翻修手术时,反肩假体可以改善这些患者的功能并减轻疼痛。我们分析了第一种治疗方法(半关节置换术与复位固定)的选择是否会影响翻修手术的结果。我们的数据表明,结果并不明显依赖于第一次植入物的选择,即使以前的半关节置换术患者有更差的结果的趋势。
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引用次数: 15
Transtendon arthroscopic repair of partial-thickness, articular surface tears of the supraspinatus: results at 2 years. 经登关节镜下修复冈上肌部分厚度的关节面撕裂:2年的结果。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0002-x
R Castricini, N Panfoli, R Nittoli, S Spurio, O Pirani

Partial-thickness articular tears of the supraspinatus represent a not uncommon event in shoulder pathology, but their treatment remains controversial. We believe that these lesions must be treated with surgical repair: we hereby describe our technique of transtendon arthroscopic repair. We have treated 33 patients with an average age of 53.3 years (range 34-69). The average follow-up was 33 months (range 26-45). The post-operative Constant score values have shown a total increase of 48.2 points (from preoperative 44.4 points to post-operative 91.6 points). In the MRI follow-up assessment no cases of retears have occurred. The use of this technique enables the reconstitution of the tendon with complete reconstruction of its footprint without damaging its intact part. We believe that this can allow a better recovery.

冈上肌部分厚度的关节撕裂在肩关节病理中并不罕见,但其治疗方法仍有争议。我们认为这些病变必须通过手术修复来治疗:我们在此描述我们的跨关节镜修复技术。我们治疗了33例患者,平均年龄53.3岁(范围34-69岁)。平均随访时间为33个月(26-45个月)。术后Constant评分值共增加48.2分(术前44.4分,术后91.6分)。在MRI随访评估中,未发现复发病例。使用这种技术可以重建肌腱,完全重建其足迹,而不会损坏其完整的部分。我们相信,这可以使经济更好地复苏。
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引用次数: 41
Culture of human rotator cuff cells on orthobiologic support (porcine small intestinal submucosa). 人肩袖细胞在原位生物支架(猪小肠粘膜下层)上的培养。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0005-7
Stefano Gumina, Anna Maria Patti, Antonella Vulcano, Carlo Della Rocca, Franco Postacchini

Outcomes obtained in patients with two-tendon rotator cuff tear submitted to repair reinforced with porcine small intestinal submucosa (SIS) have not been as encouraging as those observed in animal models. We verify the capacity of SIS to be used as a physical support for a culture of cuff cells. During arthroscopic repairs of large rotator cuff tears, we removed a fragment of supraspinatus tendon. Samples were treated for obtaining a cuff cell culture. Daily microscopic analysis, to observe adhesion to substrate, replication and cell shape was performed. A confluent monolayer was obtained in 1 week. Cells at the second passage were collected and seeded onto scaffold and cultured for 7-30 days. A morphological and immunohistochemical evaluation was performed. After 1 week, a monolayer of tendinous-like cells lay along the surface of the SIS. Within two weeks, a multicellular layer was observable in many foci of the scaffold. After a month, the cells completely invaded the numerous splits of the SIS and were positive to monoclonal anti-type I collagen antibody. Our experimental study has proved that a cuff cell culture can be performed using SIS as substrate. The culture covers the SIS surface, therefore it may reduce immune or non-specific inflammatory reactions.

采用猪小肠粘膜下层(SIS)加固修复双肌腱肩袖撕裂患者的结果并不像在动物模型中观察到的那样令人鼓舞。我们验证了SIS作为袖带细胞培养的物理支持的能力。在关节镜下修复大的肩袖撕裂时,我们切除了冈上肌腱碎片。对样品进行处理以获得袖带细胞培养。每天进行显微镜分析,观察与底物的粘附,复制和细胞形状。1周内获得融合单层。收集第二次传代细胞,接种于支架上,培养7-30天。进行形态学和免疫组织化学评价。1周后,一层腱状细胞沿着SIS表面生长。两周内,在支架的许多部位可见多细胞层。1个月后,细胞完全侵入SIS的众多分裂,单克隆抗I型胶原抗体阳性。我们的实验研究证明,可以使用SIS作为底物进行袖带细胞培养。培养物覆盖SIS表面,因此可以减少免疫或非特异性炎症反应。
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引用次数: 12
Correlation between radiographic risk for glenoid component loosening and clinical scores in shoulder arthroplasty. 肩关节置换术中肩关节假体松动的影像学风险与临床评分的相关性。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0008-4
Giovanni Merolla, Fabrizio Campi, Paolo Paladini, Nicola Lollino, Francesco Fauci, Giuseppe Porcellini

Glenoid component loosening is the weak point in the failure of total shoulder arthroplasty (TSA). In this study we analyse the radiographic risk factors observed on 86 cemented polyethylene glenoid components and their relationship with clinical signs at a mean follow-up of 5.8 years. Clinical assessment included Simple Shoulder Test (SST) and Constant-Murley score. Radiograms were taken to detect periprosthetic radiolucency, tilt, medial displacement and polyethylene thinning. Pearson's correlation coefficient and Spearman's rank correlation coefficient were calculated for statistical analysis. In 61 patients (71%) lucent lines were less than 2 mm wide (grade 2) and in 6 cases (7%) they were >or=2 mm wide (grade 3 and 4). Thinning of the polyethylene was found in 11 cases (13%), glenoid tilt in 6 cases (7%) and medial migration of the component in 5 cases (6%). Complete glenoid prosthetic loosening was found in 3 cases (3.5%) associated with polyethylene wear and glenoid bone loss. The Constant-Murley score associated with radiolucency grade 3 and 4 was less than 45% (38.39 +/- 8.9) (p < 0.05), while a score less than 56% (30.72 +/- 8.7) was found in patients with glenoid tilt and medial migration (p < 0.01). The mean SST score was 4.8 +/- 2.8 in case of glenoid tilt and migration of the component (p < 0.01). Removal of the glenoid component and conversion to hemiarthroplasty or reverse prostheses is suggested in painful glenoid loosening. An exhaustive analysis of radiograms is essential to detect early and late complications or risk factors of glenoid loosening.

肩关节假体松动是全肩关节置换术(TSA)失败的弱点。在这项研究中,我们分析了在平均5.8年的随访中观察到的86例骨水泥聚乙烯盂内假体的影像学危险因素及其与临床体征的关系。临床评价采用单纯肩部试验(SST)和Constant-Murley评分。采用x线片检测假体周围的放射透光度、倾斜、内侧位移和聚乙烯变薄。计算Pearson相关系数和Spearman秩相关系数进行统计分析。61例(71%)患者的透明线宽度小于2mm(2级),6例(7%)患者的透明线宽度>或= 2mm(3级和4级)。聚乙烯变薄11例(13%),盂骨倾斜6例(7%),内侧移位5例(6%)。3例(3.5%)假体完全松动伴聚乙烯磨损和肩关节骨丢失。放射透光度3级和4级患者的Constant-Murley评分小于45% (38.39 +/- 8.9)(p < 0.05),而肩关节倾斜和内侧移位患者的Constant-Murley评分小于56% (30.72 +/- 8.7)(p < 0.01)。肩关节倾斜和关节移位的平均SST评分为4.8 +/- 2.8 (p < 0.01)。在痛苦的关节盂松动时,建议切除关节盂组成部分,转而采用半关节置换术或反向假体。详尽的x线图分析是必要的,以发现早期和晚期并发症或危险因素的关节盂松动。
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引用次数: 15
Osteoid osteoma of the distal thumb phalanx: a case report. 拇指远端指骨骨样骨瘤1例。
Pub Date : 2008-12-01 Epub Date: 2008-12-03 DOI: 10.1007/s12306-008-0061-4
Giovanni Luigi Di Gennaro, Manuele Lampasi, Alessio Bosco, Onofrio Donzelli

Osteoid osteomas of the hand are uncommon. Particularly, location in the thumb and involvement of the distal phalanx are very rarely reported. Long diagnostic delay and inadequate treatment are typical, since clinical features may mimic other causes more frequently found in the same site (post-traumatic, infective, rheumatic, neoplastic conditions, regional pain syndrome) and even the nail morphology may be altered, as in the reported case (watch-glass deformity). A case of an osteoid osteoma of the distal thumb phalanx in a 27-year-old man is presented, along with its clinical, radiographic and CT findings. In the Authors' opinion, curettage should be considered the treatment of choice.

手部骨样骨瘤并不常见。特别是拇指的位置和远端指骨的受累很少有报道。长时间的诊断延误和治疗不充分是典型的,因为临床特征可能模仿在同一部位更常见的其他原因(创伤后、感染、风湿病、肿瘤条件、局部疼痛综合征),甚至指甲形态也可能改变,如报告的病例(手表玻璃畸形)。本文报告一27岁男性拇指远端指骨骨样骨瘤病例,并附临床、影像学和CT表现。作者认为,刮痧应被视为治疗的选择。
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引用次数: 15
Surface-based haemangioma of the tibia: a case report. 胫骨表面血管瘤1例。
Pub Date : 2008-12-01 Epub Date: 2008-10-18 DOI: 10.1007/s12306-008-0058-z
Luigi Di Giorgio, Matteo Benedetti Valentini, Marco Mastantuono, Georgios Touloupakis

We present in this paper a case of surface-based haemangioma of the tibia in a 34-year-old patient which had been misdiagnosed as periostitis. X-ray examination demonstrated a periosteal reaction, confirmed by a MRI showing a soft tissue mass adjacent to bone. We performed an incisional biopsy and made a diagnosis of haemangioma only after examining the histological results. An angiographic study was performed in order to have embolisation of the vessels, but this was not possible because of the excessive number and calibre of afferent arteries. No further symptoms arose after biopsy and therefore an en bloc or radical excision was not performed. Indications for making a correct diagnosis and performing a suitable treatment are presented below.

我们在这篇文章中提出了一例34岁的胫骨表面血管瘤患者被误诊为骨膜炎。x线检查显示骨膜反应,核磁共振证实骨旁软组织肿块。我们进行了切口活检,仅在检查组织学结果后才诊断为血管瘤。为了栓塞血管,进行了血管造影研究,但由于传入动脉的数量和口径过大,这是不可能的。活检后未出现进一步症状,因此未进行整体或根治性切除。作出正确诊断和进行适当治疗的指征如下。
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引用次数: 0
Growth factors in bone repair. 骨修复中的生长因子。
Pub Date : 2008-12-01 Epub Date: 2008-11-29 DOI: 10.1007/s12306-008-0064-1
Valentina Devescovi, Elisa Leonardi, Gabriela Ciapetti, Elisabetta Cenni

The role of growth factors (GF) in bone repair is widely recognised, particularly for bone morphogenetic proteins (BMPs), fibroblast growth factor (FGF), insulin-like growth factors (IGFs), platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-beta) and vascular endothelial growth factor (VEGF). GF are usually stored in the extracellular matrix (ECM), but after injury are actively released by ECM, cells and platelets. In this paper, the use of different recombinant GF for bone repair stimulation is summarised in experimental research and clinical applications. Drug delivery systems, including carriers, cell or gene therapy, are needed to ensure a sustained local release of the factors, but efficacy and potential side effects of such systems require additional research prior to clinical applications. Current sources for delivery of a GF mixture into the site of bone repair are platelet gel and demineralised bone matrix. Nevertheless, the levels of GF in such preparations are affected by variability among donors and differences in preparation. Autogenous GF, produced by the patient himself during the bone repair process, potentially interfere with prosthetic devices or even have a role in implant loosening due to the periprosthetic tissue reaction. In conclusion, GF are key components of functional bone regeneration: screening of basic research results and controlled clinical trials are accelerating the development of GF in orthopaedic surgery.

生长因子(GF)在骨修复中的作用已被广泛认识,特别是骨形态发生蛋白(BMPs)、成纤维细胞生长因子(FGF)、胰岛素样生长因子(IGFs)、血小板衍生生长因子(PDGF)、转化生长因子- β (tgf - β)和血管内皮生长因子(VEGF)。GF通常储存在细胞外基质(ECM)中,但在损伤后由ECM、细胞和血小板积极释放。本文就不同重组GF刺激骨修复的实验研究和临床应用进行综述。需要药物输送系统,包括载体、细胞或基因治疗,以确保因子的持续局部释放,但在临床应用之前,此类系统的功效和潜在副作用需要进一步研究。目前将GF混合物输送到骨修复部位的来源是血小板凝胶和脱矿骨基质。然而,这种制剂中的GF水平受到供体差异和制剂差异的影响。自体GF由患者自身在骨修复过程中产生,可能会干扰假体装置,甚至由于假体周围组织反应导致假体松动。综上所述,GF是功能性骨再生的关键组成部分,基础研究结果的筛选和对照临床试验正在加速GF在骨科手术中的发展。
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引用次数: 210
Viscosupplementation for grade II osteoarthritis of the ankle: a prospective study at 18 months' follow-up. 补充粘胶剂治疗II级踝关节骨关节炎:一项随访18个月的前瞻性研究。
Pub Date : 2008-12-01 Epub Date: 2008-12-06 DOI: 10.1007/s12306-008-0066-z
Deianira Luciani, Matteo Cadossi, Federico Tesei, Eugenio Chiarello, Sandro Giannini

Background: Viscosupplementation, with hyaluronan derivates injected into the intra-space of osteoarthritic joints, is now widely used for the treatment of knee osteoarthritis. This study evaluates the results in terms of pain and disability of intra-articular injections of hyaluronan derivates into the ankle joint in patients suffering from grade II primary or secondary osteoarthritis of the ankle.

Methods: Twenty-one patients with a painful ankle and radiographic evidence of grade II osteoarthritis had three weekly intra-articular injections of 2 ml of hylan G-F 20 (10 mg/ml) into the ankle joint. The primary clinical outcome measurement was the ankle osteoarthritis score (AOS) at the baseline, and at 6, 12 and 18 months.

Results: Significant improvement of the AOS from baseline was seen after 6 months (p=0.0001). This improvement was maintained over time with no further changes at 12- and 18-month follow-ups. Regarding pain, the AOS improved over time from the baseline to the 18-month follow up and became statistically significant at the 12- and 18-month follow-ups (p<0.05).

背景:将透明质酸衍生物注射到骨性关节炎关节腔内的增粘剂,目前已广泛用于膝关节骨性关节炎的治疗。本研究评估了II级原发性或继发性踝关节骨关节炎患者踝关节内注射透明质酸衍生物的疼痛和残疾的结果。方法:21例踝关节疼痛并有II级骨关节炎影像学证据的患者,每周3次向踝关节内注射2ml盐酸海兰G-F 20 (10mg /ml)。主要临床结果测量是基线、6个月、12个月和18个月的踝关节骨关节炎评分(AOS)。结果:6个月后,AOS较基线有显著改善(p=0.0001)。在12个月和18个月的随访中,这种改善一直保持着,没有进一步的变化。关于疼痛,从基线到18个月的随访,AOS随着时间的推移而改善,并在12个月和18个月的随访中变得具有统计学意义(p
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引用次数: 31
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La Chirurgia degli organi di movimento
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