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Non-ossifying fibroma, fibrous cortical defect and Jaffe-Campanacci syndrome: a biologic and clinical review. 非骨化性纤维瘤、纤维皮质缺损和Jaffe-Campanacci综合征:生物学和临床综述。
Pub Date : 2009-05-01 Epub Date: 2009-04-29 DOI: 10.1007/s12306-009-0016-4
Henry J Mankin, Carol A Trahan, Gertrud Fondren, Carole J Mankin

Non-ossifying fibroma of bone (NOF) is a common entity, more frequently found in male children and consisting of a solitary eccentric, lytic expanded lesion in the metaphysis of a long bone. The disorder is benign and most often asymptomatic but may result in a fracture requiring therapy. Of some importance is to distinguish NOF from another very similar but smaller lesion, fibrous cortical defect, which is almost always asymptomatic and eccentrically located. Even more striking is a very rarely encountered lesion known as Jaffe-Campanacci syndrome, which also occurs in children who present with typical non-ossifying fibromatous tumors but in multiple sites. In addition, these patients have some systemic and dermal findings resembling those seen in patients with Type 1 neurofibromatosis.

骨非骨化性纤维瘤(NOF)是一种常见的疾病,多见于男性儿童,由长骨干骺端孤立偏心的溶解性扩张病变组成。这种疾病是良性的,大多数情况下无症状,但可能导致骨折,需要治疗。重要的是要区分非骨失能与另一种非常相似但较小的病变,纤维皮质缺损,几乎总是无症状和偏心位置。更令人震惊的是一种罕见的病变,称为Jaffe-Campanacci综合征,它也发生在患有典型的非骨化性纤维瘤的儿童中,但在多个部位。此外,这些患者有一些与1型神经纤维瘤病患者相似的全身和皮肤表现。
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引用次数: 42
Multifocal osteosarcoma in childhood. 儿童多灶性骨肉瘤。
Pub Date : 2009-05-01 Epub Date: 2009-04-28 DOI: 10.1007/s12306-009-0015-5
Beate Kunze, Steffen Bürkle, Torsten Kluba

Osteosarcoma is one of the most common primary malignant bone tumours in childhood, mainly affecting the metaphysis of long extremity bones. In rare cases, patients present at time of diagnosis with multiple bone lesions, sometimes in the absence of pulmonary metastases. The pathology pattern of these multifocal osteosarcomas occurring with a rare incidence of 0.5-4% is not yet clear, and in spite of investigations in diagnosis and therapy, the prognosis is still poor. We report two cases of multifocal synchronous osteosarcoma. The age of both children at the time of tumour detection was 14 years. A synchronous or metachronous occurrence of multiple bone lesions, initially in the absence of pulmonary metastases was seen. In both cases, treatment consisted of neoadjuvant chemotherapy, oncologic surgery and adjuvant chemotherapy. Tumour response to chemotherapy was good in one patient, and poor in the other case. In both patients initial R0-resection of the tumours was performed. The disease-free time was 1 year before detection of pulmonary metastases or relapse. By the combination of chemotherapy and aggressive surgery the prognosis in multifocal osteosarcoma has been improved over the last years. Nevertheless, the survival time is still short and seems to be correlated with the initial histological tumour response to chemotherapy.

骨肉瘤是儿童时期最常见的原发性恶性骨肿瘤之一,主要累及四肢长骨干骺端。在罕见的病例中,患者在诊断时有多发骨病变,有时没有肺转移。这些发病率为0.5-4%的罕见多灶性骨肉瘤的病理模式尚不清楚,尽管在诊断和治疗方面进行了研究,但预后仍然很差。我们报告两例多灶性同步骨肉瘤。两个孩子发现肿瘤时的年龄都是14岁。多发性骨病变的同步或异时发生,最初未见肺转移。在这两个病例中,治疗包括新辅助化疗、肿瘤手术和辅助化疗。肿瘤对化疗的反应在一个病人中很好,在另一个病人中很差。两例患者均行肿瘤初始r0切除。无病时间为肺转移或复发前1年。近年来,通过化疗和积极手术的联合治疗,多灶性骨肉瘤的预后得到了改善。然而,生存时间仍然很短,似乎与肿瘤对化疗的初始组织学反应有关。
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引用次数: 10
Total hip arthroplasty revision in elderly people with cement and Burch-Schneider anti-protrusio cage. 骨水泥和Burch-Schneider防突出器在老年人全髋关节置换术中的应用。
Pub Date : 2009-05-01 Epub Date: 2009-04-29 DOI: 10.1007/s12306-009-0019-1
L Gaiani, R Bertelli, Massimo Palmonari, G Vicenzi

Total hip arthroplasty revision is increasingly becoming a common procedure, but the acetabular bone loss and the advanced age of the patients make revision procedures extremely complex and technically demanding. The aim of the present work is to examine the clinical and radiological results of the Burch-Schneider anti-protrusio cage (APC) implanted in revision hip arthroplasty with severe acetabular bone deficiency in elderly people. Between February 1994 and November 2005, a total of 60 revision operations of acetabular components were performed in 60 select patients (42 females and 18 males), using the Burch-Schneider APC. The indication for the Burch-Schneider APC use was massive pelvic bone loss with migration of the prosthesis cup and high-grade acetabular defects (type III or IV AAOS). The mean age at the time of surgery was 82 years (range 78-85 years). Polymethylmetacrylate cement (PMMA) was used to fill bony deficiencies in all the procedures. No graft was used. The average Harris Hip Score had improved from 28.2 preoperatively to 82.5 points at the time of follow-up. According to the classification of Gill et al., we have seen no Burch-Schneider cages definitely loose or probably. Only one acetabular component has been revised (for recurrent dislocation). Acetabular reconstruction with the use of cement and an acetabular support ring appears to have a useful role in the treatment of severe acetabular bony deficiency in elderly patients and may provide a definitive reconstruction.

全髋关节置换术翻修正日益成为一种常见的手术,但髋臼骨丢失和患者的高龄使得翻修手术极其复杂和技术要求很高。本研究的目的是研究Burch-Schneider抗突笼(APC)在老年人严重髋臼骨缺乏翻修髋关节置换术中的临床和影像学结果。在1994年2月至2005年11月间,我们选择了60例患者(42例女性,18例男性)使用Burch-Schneider APC进行了共60例髋臼假体翻修手术。Burch-Schneider APC的适应症是大量骨盆骨丢失伴假体杯移位和高度髋臼缺损(III型或IV型AAOS)。手术时的平均年龄为82岁(78-85岁)。所有手术均采用聚甲基丙烯酸甲酯骨水泥(PMMA)填补骨缺损。未使用移植物。Harris髋关节平均评分从术前的28.2分提高到随访时的82.5分。根据Gill等人的分类,我们没有看到肯定松动或可能松动的Burch-Schneider笼。只有一个髋臼部件被修正(用于复发性脱位)。使用骨水泥和髋臼支撑环进行髋臼重建术在治疗老年患者严重髋臼骨缺损中似乎具有有用的作用,并可能提供明确的重建。
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引用次数: 22
Subchondral osteoid osteoma of the glenoid. 关节盂软骨下骨样骨瘤。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0011-9
Oguz Poyanli, Koray Unay, Kaya Akan, Korhan Ozkan, Duygu Temiz

Osteoid osteoma of the scapula is a rare benign lesion. This is a case report of a subchondral osteoid osteoma that involved the anterior rim of glenoid. Surgical approach in this atypical area may seem difficult. The excision of the lesion and grafting was performed by a deltopectoral approach. One year after the surgery, the patient remains pain free and has full range of motion with no recurrence of the tumour.

肩胛骨类骨瘤是一种罕见的良性病变。这是一个涉及关节盂前缘软骨下骨样骨瘤的病例报告。这种非典型区域的手术入路似乎很困难。病变切除和移植通过三角胸侧入路进行。手术后一年,患者无疼痛,活动范围全,肿瘤无复发。
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引用次数: 7
The "Helix Wire": our experience in the treatment of humeral neck fractures. “螺旋钢丝”:我们治疗肱骨颈骨折的经验。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0012-8
Roberto Valentini, Bruno Martinelli

The management of proximal humeral fractures is still controversial and no single treatment has been unanimously accepted. This paper focuses on displaced two-part fractures to describe the minimally invasive fixation device known as Helix Wire and to propose precise indications for its use, partly on the basis of our previous study of its mechanical properties. Thirty patients with nondisplaced and displaced humeral neck fractures were treated with implantation of a Helix Wire between January 2005 and September 2005. Clinical and radiographic follow-up was carried out at 1, 2, 6 and 12 months. Clinical and functional assessment was performed using the Constant-Murley score. The results at 1 year after surgery were excellent in 7 cases (23.3%), good in 14 cases (46.6%), fair in 8 cases (26.6%) and poor in 1 case (3.3%). On the basis of our precise indications, elderly patients with nondisplaced or displaced two-part fractures of the proximal humerus may achieve good results with minimally invasive implantation of the Helix Wire.

肱骨近端骨折的治疗仍然存在争议,没有一种治疗方法被一致接受。本文着重于移位的两部分骨折,以描述称为Helix Wire的微创固定装置,并提出其使用的精确适应症,部分基于我们之前对其机械性能的研究。本研究于2005年1月至2005年9月期间对30例肱骨颈非移位和移位骨折患者进行了螺旋钢丝植入治疗。分别于1、2、6和12个月进行临床和影像学随访。采用Constant-Murley评分进行临床和功能评估。术后1年疗效:优7例(23.3%),良14例(46.6%),一般8例(26.6%),差1例(3.3%)。根据我们精确的指征,老年肱骨近端非移位或移位两部分骨折患者采用微创植入Helix Wire可获得良好的效果。
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引用次数: 0
Telegraph antegrade nailing in the treatment of humeral fractures with rotator interval split technique. 螺旋顺行钉治疗肱骨骨折的疗效观察。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0009-3
Raffaele Russo, Fabio Cautiero, Luigi Vernaglia Lombardi, Valeria Visconti

Twenty-four proximal humeral fractures were treated by surgical internal fixation with a locked antegrade intramedullary nail. The purpose of this paper was to assess the clinical outcomes of proximal epiphyseal and diaphyseal humeral fractures treated with an antegrade humeral nail implanted after an interval rotator split. We treated six proximal epiphyseal fractures and seven bifocal fractures of the epiphysis and shaft and eleven diaphyseal fractures. The mean follow-up was 23 months (range 12 to 34 months). Twenty patients were available for follow-up. All but two fractures progressed to healing. The Mean Constant score was 80%, Relative Constant score was 95.5%. We divided the clinical outcomes by fracture pattern to define the best surgical indication. There were good clinical outcomes in all three groups, but the clinical score was highest in the shaft fracture group. An intramedullary antegrade nail inserted through the interval rotator without penetrating the rotator cuff had a good clinical outcome and with certain fracture types can be an effective and satisfactory device.

24例肱骨近端骨折采用顺行锁髓内钉手术内固定治疗。本文的目的是评估肱骨近端骨骺和骨干骨折的临床结果,肱骨顺行肱骨钉植入术治疗肱骨近端骨骺和骨干骨折。我们治疗了6例近端骨骺骨折、7例骨骺及骨干双焦点骨折和11例骨干骨折。平均随访23个月(12 ~ 34个月)。20例患者可随访。除两处骨折外,其余骨折均已愈合。平均常数评分为80%,相对常数评分为95.5%。我们将临床结果按骨折类型划分,以确定最佳手术指征。三组临床疗效均较好,但以轴骨折组临床评分最高。髓内顺行髓内钉不穿入肩袖,经间段旋转器内插入具有良好的临床效果,对于某些骨折类型是一种有效且令人满意的治疗方法。
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引用次数: 5
Post-operative rehabilitation after surgical repair of the rotator cuff. 肩袖手术修复后的术后康复。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0003-9
Marco Conti, Raffaele Garofalo, Giacomo Delle Rose, Giuseppe Massazza, Enzo Vinci, Mario Randelli, Alessandro Castagna

Today advances in techniques and materials for rotator cuff surgery allow the repair of a large variety of types or extensions of cuff lesions in patients from a wide range of age groups who have different kinds of jobs and participate in different kinds of sports, and who have widely different expectations in terms of recovery of functions and pain relief. A large number of factors must be taken into account before implementing a rehabilitation protocol after rotator cuff surgery. These mainly include the technique (materials and procedure) used by the surgeon. Moreover, tissue quality, retraction, fatty infiltration and time from rupture are important biological factors while the patient's work or sport or daily activities after surgery and expectations of recovery must also be assessed. A rehabilitation protocol should also take into account the timing of biological healing of bone to tendon or tendon to tendon interface, depending on the type of rupture and repair. This timing should direct the therapist's choice of correct passive or assisted exercise and mobilisation manoeuvres and the teaching of correct active mobilisation movements the patient has to do. Following accepted knowledge about the time of biological tissue healing, surgical technique and focused rehabilitation exercise, a conceptual protocol in four phases could be applied, tailoring the protocol for each patient. It starts with sling rest with passive small self-assisted arm motion in phase one, to prevent post-op stiffness. In phase two passive mobilisation by the patient dry or in water, integrated with scapular mobilisation and stabiliser reinforcement, are done. Phase three consists of progressive active arm mobilisation dry or in water integrated with proprioceptive exercise and "core" stabilisation. In phase four full strength recovery integrated with the recovery of work or sports movements will complete the protocol. Because of the multi-factorial aspects of the problem, the best results can be obtained through a full transfer of information from the surgeon to the therapist to optimise timing and sizing of the individual rehabilitation protocol for each patient.

今天,肩袖手术的技术和材料的进步允许修复各种类型或扩展的肩袖病变,患者来自不同年龄段,从事不同类型的工作,参加不同类型的运动,对功能恢复和疼痛缓解有不同的期望。在实施肩袖手术后的康复方案之前,必须考虑许多因素。这些主要包括外科医生使用的技术(材料和程序)。此外,组织质量、收缩、脂肪浸润和破裂时间是重要的生物学因素,同时还必须评估患者术后的工作或运动或日常活动以及恢复的期望。康复方案还应考虑到骨对肌腱或肌腱对肌腱界面的生物愈合时间,这取决于断裂和修复的类型。这个时机应该指导治疗师选择正确的被动或辅助运动和活动,以及教授患者必须做的正确的主动活动。根据关于生物组织愈合时间、手术技术和重点康复训练的公认知识,可以应用一个分为四个阶段的概念性方案,为每位患者量身定制方案。首先是吊带休息,在第一阶段进行被动的小自主手臂运动,以防止术后僵硬。在第二阶段,患者在干燥或水中进行被动活动,结合肩胛骨活动和稳定剂加固。第三阶段包括渐进式主动手臂活动,干燥或水中,结合本体感觉锻炼和“核心”稳定。在第四阶段,全力量恢复结合工作或运动的恢复将完成协议。由于问题的多因素方面,通过从外科医生到治疗师的充分信息传递,以优化每个患者的个体康复方案的时间和规模,可以获得最佳结果。
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引用次数: 42
Non-purulent low-grade infection as cause of pain following shoulder surgery: preliminary results. 肩部手术后引起疼痛的非化脓性低度感染:初步结果。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0010-x
Alberto G Schneeberger, Michael K Gilbart, Ralph Sheikh, Christian Gerber, Christian Ruef

Low-grade infection was systematically searched for in all revision shoulder surgeries by harvesting tissue samples. Ten consecutive patients were identified with a non-purulent low-grade infection of the shoulder. All of these patients suffered from pain and eight were stiff. Preoperative aspiration in eight patients yielded bacterial growth in only one case. Serum C-reactive protein levels were normal in seven out of 10 cases. Propionibacterium acnes was identified in seven, coagulase-negative Staphylococcus in two and Staphylococcus saccharolyticus in one case. The delay between harvesting the tissue samples and detection of bacterial growth averaged eight days (range, 2-17). After debridement and antibiotic treatment for a mean of 4.5 months, tissue samples were repeatedly harvested in nine patients due to persistent pain. The infection was microbiologically eradicated in six out of nine cases that had a repeated biopsy. However, nine out of 10 patients continued to suffer from moderate to severe pain. Low-grade infection of the shoulder can be a cause of persistent pain and stiffness. The results of antibiotic treatment are disappointing. Further studies are necessary to analyse this difficult pathology.

在所有肩部翻修手术中,通过收集组织样本系统地搜索低级别感染。连续10例患者被确定为肩部非化脓性低度感染。所有患者都感到疼痛,其中8人僵硬。8例患者术前抽吸仅1例出现细菌生长。10例患者中有7例血清c反应蛋白水平正常。其中痤疮丙酸杆菌7例,凝固酶阴性葡萄球菌2例,溶糖葡萄球菌1例。采集组织样本和检测细菌生长之间的延迟平均为8天(范围2-17天)。在平均4.5个月的清创和抗生素治疗后,由于持续疼痛,9名患者反复采集组织样本。在9例重复活检的病例中,有6例的感染被微生物根除。然而,10名患者中有9名继续遭受中度至重度疼痛。轻度的肩部感染可引起持续的疼痛和僵硬。抗生素治疗的结果令人失望。需要进一步的研究来分析这一困难的病理。
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引用次数: 34
Comminuted periprosthetic humeral fracture after reverse shoulder prosthesis. 反向肩关节假体术后肱骨周围粉碎性骨折。
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0013-7
Renato Sommacal, Hans Rudolph Bloch, Adriana Ghidelli, Graziano Bettelli, Paolo Dalla Pria

Periprosthetic fractures represent a severe complication after joint replacement. A case of comminuted displaced humeral fracture around the stem of a SMR reverse shoulder prosthesis is reported. The patient was a 81-year-old lady who had had a total shoulder replacement 28 months previously. The surgical solution consisted of a partial revision of the modular implant with conservation not only of the glenoid component but also of the prosthetic humeral body, which was well fixed in the humeral metaphysis. The humeral stem was removed and a long uncemented revision stem was implanted providing fracture stabilisation and allowing early mobilisation.

假体周围骨折是关节置换术后的严重并发症。报告一例SMR反向肩关节假体周围粉碎性移位肱骨骨折。患者是一位81岁的女士,28个月前接受了全肩关节置换术。手术解决方案包括对模块化植入物进行部分翻修,不仅保留了关节盂成分,而且保留了假体肱骨,使其在肱骨干骺端固定得很好。移除肱骨柄,植入一长段非骨水泥修复柄,提供骨折稳定并允许早期活动。
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引用次数: 6
Correlations between biochemical markers in the synovial fluid and severity of rotator cuff disease. 滑液生化指标与肩袖疾病严重程度的相关性
Pub Date : 2009-04-01 DOI: 10.1007/s12306-009-0004-8
M S Tajana, L Murena, F Valli, A Passi, F A Grassi

The role of biochemical factors in the onset and natural history of rotator cuff disease is not fully understood, but it is generally recognised that they could induce tendon damage in association with mechanical and vascular factors. In this study, 5 biochemical parameters were analysed (total protein concentration, matrix metalloproteinase (MMP)-2 or gelatinase A, MMP-9 or gelatinase B, type I collagen telopeptides, hyaluronic acid) in the synovial fluid (SF) aspirated from the gleno-humeral joint of 29 patients undergoing surgical therapy for rotator cuff lesions. Four different groups of patients were identified according to the severity of the lesion: partial tear of the rotator cuff, full thickness tear involving 1 tendon and cuff tear arthropathy (CTA). The total SF protein concentration progressively increased with loss of integrity of the rotator cuff, reaching the highest levels in CTA. The absolute enzymatic activity of gelatinases was greater in full thickness tears than in partial tears, while it decreased in CTA. Conversely, the ratio between gelatinases and total protein content reached the highest level in partial tears and then progressively decreased. Collagen I telopeptides were significantly increased in full thickness tears and CTA, whereas the levels of hyaluronic acid decreased with worsening of rotator cuff disease. These findings support the hypothesis that gelatinases, which are involved in physiological tendon remodelling, intervene in the evolution of rotator cuff disease, too. Increased levels of type I collagen telopeptides give evidence that tendon tears are associated with an anatomic loss of tendon tissue and not with simple tendon retraction.

生化因素在肩袖疾病的发病和自然史中的作用尚不完全清楚,但人们普遍认为,它们可能与机械和血管因素相关,导致肌腱损伤。本研究分析了29例接受肩袖病变手术治疗的肱骨关节滑液(SF)中的5个生化参数(总蛋白浓度、基质金属蛋白酶(MMP)-2或明胶酶A、MMP-9或明胶酶B、I型胶原端肽、透明质酸)。根据病变严重程度将患者分为四组:部分肩袖撕裂、1根肌腱全层撕裂和肩袖撕裂关节病(CTA)。随着肩袖完整性的丧失,总SF蛋白浓度逐渐增加,在CTA时达到最高水平。明胶酶的绝对酶活性在全层泪液中高于部分泪液,而在CTA中则降低。相反,明胶酶与总蛋白含量之比在部分撕裂中达到最高水平,然后逐渐降低。胶原I端肽在全层撕裂和CTA中显著增加,而透明质酸水平随着肩袖疾病的恶化而下降。这些发现支持了明胶酶参与生理肌腱重塑的假设,也干预了肩袖疾病的演变。I型胶原末端肽水平的升高证明肌腱撕裂与肌腱组织的解剖性损失有关,而不是单纯的肌腱缩回。
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引用次数: 23
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La Chirurgia degli organi di movimento
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