The purpose of this study was to measure the amount of formaldehyde released from three types of endodontic sealing cement (AH-Plus, EZ-Fill, and AH-26). Formaldehyde release was analyzed using High Performance Liquid Chromatography, which could detect as low as 0.25 ppm. The data was tabulated after two runs. The two paste system of AH-Plus endodontic sealing cement had the least amount of formaldehyde release (0.00039%, 3.9 ppm). This was followed by EZ-Fill (0.054%, 540 ppm) endodontic cement and AH-26 (0.1347%, 1347 ppm) endodontic cement which yielded the greatest formaldehyde release. Both of these cements (EZ-Fill and AH-26 endodontic filling cements) are based on a powder-liquid mix. The relative minute amounts of formaldehyde released by the endodontic cements studied (AH-Plus and EZ-Fill) warrant their use as endodontic sealing cements.