首页 > 最新文献

Research and clinical studies in headache最新文献

英文 中文
Headache determination by meteorotropic influences. 受气象影响的头痛测定。
Research and clinical studies in headache
Pub Date : 1978-01-01 DOI: 10.1159/000402452
J. Kugler, M. Laub
Using the biometeorologic system proposed by Brezowsky, the chronological distribution of migraine attacks was analysed in 4 patients over a 5-year period. A correlation of complaints with physical indices (atmospheric pressure, temperature, humidity and ionisation) could not be established. However, a significantly high incidence of headache symptoms was shown in the biometeorologic phase 6Z (although other investigators have reported such an increase in weather phases 3 and 4). The important common denominator of these weather phases seems to be a disturbed circadian rhythm which interferes with endogenous biorhythms and triggers attacks of headache.
采用Brezowsky提出的生物气象学系统，分析了4例患者5年内偏头痛发作的时间分布。不能确定抱怨与物理指标(大气压、温度、湿度和电离)之间的相关性。然而，在生物气象阶段6Z中显示出头痛症状的显著高发生率(尽管其他研究人员报告了天气阶段3和4的增加)。这些天气阶段的重要共同点似乎是昼夜节律紊乱，干扰内源性生物节律并引发头痛发作。
{"title":"Headache determination by meteorotropic influences.","authors":"J. Kugler, M. Laub","doi":"10.1159/000402452","DOIUrl":"https://doi.org/10.1159/000402452","url":null,"abstract":"Using the biometeorologic system proposed by Brezowsky, the chronological distribution of migraine attacks was analysed in 4 patients over a 5-year period. A correlation of complaints with physical indices (atmospheric pressure, temperature, humidity and ionisation) could not be established. However, a significantly high incidence of headache symptoms was shown in the biometeorologic phase 6Z (although other investigators have reported such an increase in weather phases 3 and 4). The important common denominator of these weather phases seems to be a disturbed circadian rhythm which interferes with endogenous biorhythms and triggers attacks of headache.","PeriodicalId":76420,"journal":{"name":"Research and clinical studies in headache","volume":"12 1","pages":"117-22"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80159642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Toleration and effectiveness of pizotifen in migraine. 匹唑替芬治疗偏头痛的耐受性和有效性。
Research and clinical studies in headache
Pub Date : 1978-01-01
H E Mikropoulos
{"title":"Toleration and effectiveness of pizotifen in migraine.","authors":"H E Mikropoulos","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76420,"journal":{"name":"Research and clinical studies in headache","volume":"6 ","pages":"167-72"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11925146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studies on the 5-HT receptor in vascular smooth muscle. 血管平滑肌5-HT受体的研究。
Research and clinical studies in headache
Pub Date : 1978-01-01
E Müller-Schweinitzer

Changes in tension were monitored isometrically on spiral strips of freshly obtained bovine basilar arteries. Ergotamine (E), dihydroergotamine (DHE), methysergide (M) and pizotifen (BC-105) displaced the concentration-response curve for 5-HT in a noncompetitive way and in similar concentration ranges as indicated by the pD' 2(60 min) values of the three ergot alkaloids (E: 9.2, M: 9.1, DHE: 8.8) and the pD' 2(30 min) value (8.9) of BC-105. The ergot alkaloids but not BC-105 also exhibited considerable stimulating activity. The calculated pD2 values were 8.8 for E, 8.6 for DHE and 6.6 for M. Relative to 5-HT (= 1) the intrinsic activities were 0.4, 0.2 and 0.1 for E, DHE and M, respectively. BC-105 was nearly equipotent in antagonizing responses to 5-HT, E and DHE suggesting that both ergot alkaloids act as noncompetitive dualists at the 5-HT receptor. The results suggest that the strong stimulant rather than the blocking activity at the 5-HT receptor of ergotamine may be an important property for its therapeutic efficacy in migrainous attacks.

张力的变化是在新鲜获得的牛基底动脉螺旋条上等距监测的。麦角胺(E)、二氢麦角胺(DHE)、甲基塞夫胺(M)和匹唑芬(BC-105)以非竞争的方式取代了5-羟色胺的浓度-响应曲线，并且在相似的浓度范围内，三种麦角生物碱(E: 9.2, M: 9.1, DHE: 8.8)的pD' 2(60 min)值和BC-105的pD' 2(30 min)值(8.9)。除BC-105外，麦角生物碱也表现出较强的刺激活性。与5-HT(= 1)相比，E、DHE和M的内在活性分别为0.4、0.2和0.1,DHE和M的内在活性分别为8.8、8.6和6.6。BC-105对5-HT、E和DHE的拮抗作用几乎相同，表明这两种麦角生物碱在5-HT受体中起非竞争性二元作用。结果提示，麦角胺治疗偏头痛的重要作用可能是其强烈的兴奋作用而不是对5-HT受体的阻断作用。
{"title":"Studies on the 5-HT receptor in vascular smooth muscle.","authors":"E Müller-Schweinitzer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Changes in tension were monitored isometrically on spiral strips of freshly obtained bovine basilar arteries. Ergotamine (E), dihydroergotamine (DHE), methysergide (M) and pizotifen (BC-105) displaced the concentration-response curve for 5-HT in a noncompetitive way and in similar concentration ranges as indicated by the pD' 2(60 min) values of the three ergot alkaloids (E: 9.2, M: 9.1, DHE: 8.8) and the pD' 2(30 min) value (8.9) of BC-105. The ergot alkaloids but not BC-105 also exhibited considerable stimulating activity. The calculated pD2 values were 8.8 for E, 8.6 for DHE and 6.6 for M. Relative to 5-HT (= 1) the intrinsic activities were 0.4, 0.2 and 0.1 for E, DHE and M, respectively. BC-105 was nearly equipotent in antagonizing responses to 5-HT, E and DHE suggesting that both ergot alkaloids act as noncompetitive dualists at the 5-HT receptor. The results suggest that the strong stimulant rather than the blocking activity at the 5-HT receptor of ergotamine may be an important property for its therapeutic efficacy in migrainous attacks.</p>","PeriodicalId":76420,"journal":{"name":"Research and clinical studies in headache","volume":"6 ","pages":"6-12"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11925151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A survey of headache in an English city. 英国某城市头痛调查。
Research and clinical studies in headache
Pub Date : 1978-01-01 DOI: 10.1159/000401332
C. Newland, L. Illis, P. K. Robinson, B. Batchelor, W. Waters
{"title":"A survey of headache in an English city.","authors":"C. Newland, L. Illis, P. K. Robinson, B. Batchelor, W. Waters","doi":"10.1159/000401332","DOIUrl":"https://doi.org/10.1159/000401332","url":null,"abstract":"","PeriodicalId":76420,"journal":{"name":"Research and clinical studies in headache","volume":"24 1","pages":"1-20"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78517535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 52
Headache today--an update by 21 experts. 今日头痛——由21位专家更新。
Research and clinical studies in headache
Pub Date : 1978-01-01 DOI: 10.1159/isbn.978-3-318-04047-0
Arnold P. Friedman, Mary E. Granger, Macdonald Critchley
{"title":"Headache today--an update by 21 experts.","authors":"Arnold P. Friedman, Mary E. Granger, Macdonald Critchley","doi":"10.1159/isbn.978-3-318-04047-0","DOIUrl":"https://doi.org/10.1159/isbn.978-3-318-04047-0","url":null,"abstract":"","PeriodicalId":76420,"journal":{"name":"Research and clinical studies in headache","volume":"15 1","pages":"1-128"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80383419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Chronic brain stimulation for the treatment of intractable pain. 慢性脑刺激治疗顽固性疼痛。
Research and clinical studies in headache
Pub Date : 1978-01-01 DOI: 10.1159/000401340
Y. Hosobuchi
{"title":"Chronic brain stimulation for the treatment of intractable pain.","authors":"Y. Hosobuchi","doi":"10.1159/000401340","DOIUrl":"https://doi.org/10.1159/000401340","url":null,"abstract":"","PeriodicalId":76420,"journal":{"name":"Research and clinical studies in headache","volume":"48 1","pages":"122-6"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76958346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Chronic brain stimulation for the treatment of intractable pain. 慢性脑刺激治疗顽固性疼痛。
Research and clinical studies in headache
Pub Date : 1978-01-01
Y Hosobuchi
{"title":"Chronic brain stimulation for the treatment of intractable pain.","authors":"Y Hosobuchi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76420,"journal":{"name":"Research and clinical studies in headache","volume":"5 ","pages":"122-6"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11520945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computerized axial tomography of migraine. 偏头痛的计算机轴位断层扫描。
Research and clinical studies in headache
Pub Date : 1978-01-01
W S Masland, A P Friedman, H W Buchsbaum
{"title":"Computerized axial tomography of migraine.","authors":"W S Masland,&nbsp;A P Friedman,&nbsp;H W Buchsbaum","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76420,"journal":{"name":"Research and clinical studies in headache","volume":"6 ","pages":"136-40"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11925142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reflex vasomotor function: clinical and experimental studies in migraine. 反射性血管舒缩功能:偏头痛的临床和实验研究。
Research and clinical studies in headache
Pub Date : 1978-01-01
O Appenzeller
{"title":"Reflex vasomotor function: clinical and experimental studies in migraine.","authors":"O Appenzeller","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76420,"journal":{"name":"Research and clinical studies in headache","volume":"6 ","pages":"160-6"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11925145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spasmogen release from an extracranial vascular bed evoked by neurohumoral stimuli and periods of vascular stasis. 由神经体液刺激和血管停滞期引起的颅内外血管床痉挛素释放。
Research and clinical studies in headache
Pub Date : 1978-01-01
J R Fozard, S R Carr

The hypothesis that pro-inflammatory spasmogens may be generated locally in the vessels of the head by neurohumoral stimuli has been tested using an isolated extracranial vascular bed from the rabbit. No spasmogen release was detected after adenosine triphosphate, histamine, acetylcholine or noradrenaline and was seen rarely after tyramine and 5-hydroxytryptamine. Both sympathetic nerve stimulation and periods of vascular stasis released spasmogen, probably an E-type prostaglandin. The local generation of pro-inflammatory substances by excess sympathetic stimulation and/or vascular stasis might contribute to the development and maintenance of the acute migraine attack.

关于促炎痉挛原可能通过神经体液刺激在头部血管中局部产生的假设已经通过兔的分离颅外血管床进行了验证。三磷酸腺苷、组胺、乙酰胆碱、去甲肾上腺素后未见痉挛素释放，酪胺、5-羟色胺后少见。交感神经刺激和血管停滞期都会释放痉挛素，可能是一种e型前列腺素。过度的交感神经刺激和/或血管淤滞在局部产生促炎物质可能有助于急性偏头痛发作的发展和维持。
{"title":"Spasmogen release from an extracranial vascular bed evoked by neurohumoral stimuli and periods of vascular stasis.","authors":"J R Fozard,&nbsp;S R Carr","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The hypothesis that pro-inflammatory spasmogens may be generated locally in the vessels of the head by neurohumoral stimuli has been tested using an isolated extracranial vascular bed from the rabbit. No spasmogen release was detected after adenosine triphosphate, histamine, acetylcholine or noradrenaline and was seen rarely after tyramine and 5-hydroxytryptamine. Both sympathetic nerve stimulation and periods of vascular stasis released spasmogen, probably an E-type prostaglandin. The local generation of pro-inflammatory substances by excess sympathetic stimulation and/or vascular stasis might contribute to the development and maintenance of the acute migraine attack.</p>","PeriodicalId":76420,"journal":{"name":"Research and clinical studies in headache","volume":"6 ","pages":"41-52"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11925149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
类型
全部 化学•材料 生命科学 医学 物理 工程技术 环境•农林 材料科学 地球科学 法学 管理学 化学 环境科学与生态学 计算机科学 教育学 经济学 农林科学 人文科学 生物学 数学 物理与天体物理 心理学 综合性期刊 其他 工业工程 理学 历史学 农学 文学 信息工程
数据库
全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley
期刊
Research and clinical studies in headache
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
﹀
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们：info@booksci.cn
Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1