{"title":"[Conclusions drawn about the current situation of antitubercular chemotherapy in Romania based on the 1987 national evaluation questionnaire].","authors":"C Anastasatu, E Corlan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76439,"journal":{"name":"Revista de igiena, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Pneumoftiziologia","volume":"38 2","pages":"157-68"},"PeriodicalIF":0.0,"publicationDate":"1989-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13698754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Compliance with antitubercular chemotherapy, a central element in the efficacy of a national program].","authors":"E Corlan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76439,"journal":{"name":"Revista de igiena, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Pneumoftiziologia","volume":"38 2","pages":"187-91"},"PeriodicalIF":0.0,"publicationDate":"1989-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13699236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I Jemna, D Cioflec, N Ion, O Hudiţeanu, I Lego, I Simon
The data in the present paper consider, for a longer period, the secondary and the initial drug resistance in pulmonary and extrapulmonary tuberculosis. The paper studies mainly the period of the last 9 years (1979-1987) in comparison with a previous period of 6 years (1973-1978). The 2,194 antibiograms performed for 7 common tuberculostatics show an increase, in the last years, of the general resistance of the germs from 24.3% to 36%. The increase of the resistance is noticed to all the tuberculostatics, but mainly to Rifampicin, from 14.8% to 49.3% and to streptomycin, from 22.7% to 44.8%. An important increase is found, at present, mainly in the drug resistance of germs in the extrapulmonary specimens (lymph nodes 28.5% and CSF 40%) to streptomycin and INH.
{"title":"[The current situation of mycobacterial chemoresistance and its implications for antitubercular treatment].","authors":"I Jemna, D Cioflec, N Ion, O Hudiţeanu, I Lego, I Simon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The data in the present paper consider, for a longer period, the secondary and the initial drug resistance in pulmonary and extrapulmonary tuberculosis. The paper studies mainly the period of the last 9 years (1979-1987) in comparison with a previous period of 6 years (1973-1978). The 2,194 antibiograms performed for 7 common tuberculostatics show an increase, in the last years, of the general resistance of the germs from 24.3% to 36%. The increase of the resistance is noticed to all the tuberculostatics, but mainly to Rifampicin, from 14.8% to 49.3% and to streptomycin, from 22.7% to 44.8%. An important increase is found, at present, mainly in the drug resistance of germs in the extrapulmonary specimens (lymph nodes 28.5% and CSF 40%) to streptomycin and INH.</p>","PeriodicalId":76439,"journal":{"name":"Revista de igiena, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Pneumoftiziologia","volume":"38 2","pages":"143-8"},"PeriodicalIF":0.0,"publicationDate":"1989-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13698750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Botis, P P Koemoth, J M Correa de Brito, M Brock
The action of auramine on the growth of some mycobacterial strains in 7H12 Middlebrook liquid medium as well as the interaction between auramine and calf thymus DNA were investigated. It was concluded that the inhibitory effect of auramine on the growth of some mycobacterial strains belonging to the TB complex or MOTT bacilli is the result of a double mechanism: interaction of auramine with mycolic acid and interaction between the dye and the mycobacterial DNA.
{"title":"Growth of some mycobacterial strains in 7H12 Middlebrook liquid medium in the presence of auramine.","authors":"S Botis, P P Koemoth, J M Correa de Brito, M Brock","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The action of auramine on the growth of some mycobacterial strains in 7H12 Middlebrook liquid medium as well as the interaction between auramine and calf thymus DNA were investigated. It was concluded that the inhibitory effect of auramine on the growth of some mycobacterial strains belonging to the TB complex or MOTT bacilli is the result of a double mechanism: interaction of auramine with mycolic acid and interaction between the dye and the mycobacterial DNA.</p>","PeriodicalId":76439,"journal":{"name":"Revista de igiena, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Pneumoftiziologia","volume":"38 2","pages":"137-41"},"PeriodicalIF":0.0,"publicationDate":"1989-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13626027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Coma--accidental poisoning occurring in the isoniazid + rifampicin treatment of a 7-year-old child].","authors":"G Murgoci","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76439,"journal":{"name":"Revista de igiena, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Pneumoftiziologia","volume":"38 2","pages":"149-56"},"PeriodicalIF":0.0,"publicationDate":"1989-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13698751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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