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American Journal of Contact Dermatitis最新文献

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CELLULAR CHARACTERIZATION OF OCCUPATIONAL CONTACT DERMATITIS: 16 职业性接触性皮炎的细胞特征
Pub Date : 2002-06-01 DOI: 10.1097/01206501-200206000-00028
M. Khorramizadeh, M. Pezeshki, P. Mansouri, R. Falak, F. Safavifar, A. Ghahary
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引用次数: 0
Diagnostic screening for contact allergy to mercaptobenzothiazole derivatives 巯基苯并噻唑类衍生物接触性过敏的诊断筛查
Pub Date : 2002-06-01 DOI: 10.1053/ajcd.2002.32857
Johannes Geier, Wolfgang Uter, Axel Schnuch, Jochen Brasch, Olaf Gefeller for the German Contact Dermatitis Research Group (DKG) and the Information Network of Departments of Dermatology (IVDK)

Background: A patch test with an allergen mix used as screening test should be highly sensitive so that allergic patients are not missed. A previous analysis based on patch test data from 1990 to 1993 has shown that the mercapto mix lacked sensitivity. Chemical analyses on the stability of the mix components led to a new composition of the mix in 1995. Methods: The authors analyzed retrospectively patch test data from the Information Network of Departments of Dermatology to evaluate the sensitivity of the newly formulated mercapto mix and mercaptobenzothiazole (MBT) for detecting contact allergies to the 3 MBT derivatives contained in the present mix. Results: The new mercapto mix had a sensitivity of only 0.60, whereas MBT had a significantly higher sensitivity of 0.69. However, even this means that more than 30% of the patients allergic to MBT derivatives are missed. The combination of MBT and mercapto mix had a sensitivity of 0.77 for detecting contact allergies to the MBT derivatives. Conclusion: The German Contact Dermatitis Research Group decided to test both mercapto mix and MBT within the standard series, and to apply the 3 single components of the mix in case of a positive reaction to the mix or MBT.

背景:使用过敏原混合物的斑贴试验作为筛选试验应该是高度敏感的,这样过敏患者才不会被遗漏。先前一项基于1990年至1993年斑贴试验数据的分析表明,硫醇混合物缺乏敏感性。1995年,对混合成分稳定性的化学分析导致了一种新的混合成分。方法:回顾性分析来自皮肤科信息网络的斑贴试验数据,评价新配制的巯基苯并噻唑(MBT)和巯基苯并噻唑(MBT)对现有混合物中3种MBT衍生物的接触性过敏检测的敏感性。结果:新的硫醇混合物的灵敏度仅为0.60,而MBT的灵敏度为0.69。然而,即使这样也意味着超过30%的对MBT衍生物过敏的患者被遗漏了。MBT与硫醇混合物组合检测MBT衍生物接触性过敏的灵敏度为0.77。结论:德国接触性皮炎研究小组决定在标准系列内测试硫醇混合物和MBT,如果混合物或MBT反应阳性,则使用混合物的3种单一成分。
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引用次数: 24
Rate of patch test reactions to a Dermatophagoides mix currently on the market: A mite too sensitive? 对目前市场上的一种去皮药混合物的斑贴试验反应率:是不是太敏感了?
Pub Date : 2002-06-01 DOI: 10.1053/ajcd.2002.33329
Mark D.P. Davis, Donna M. Richardson, Debra D.F. Ahmed

Background: There long has been debate over the role of the dust mite antigen Dermatophagoides in provoking or perpetuating atopic and other forms of dermatitis, particularly airborne contact dermatitis. Reactivity to Dermatophagoides has been measured by specific IgE and by immediate-type responses to prick test challenge. More recently, patch testing has been advocated as a means of determining reactivity to Dermatophagoides.Objective: To determine patch test reactivity to a Dermatophagoides mix in a population receiving patch testing. Methods: A commercially available mix of 2 species of Dermatophagoides, Dermatophagoides pteronyssinus and Dermatophagoides farinae, recently became available. The authors chose the lower available concentration of this mix (20%) and added it to their standard patch testing tray between December 1999 and January 2001. Results were interpreted in the standard manner. Results: A total of 662 patients received patch testing to Dermatophagoides (men 32%, women, 68%). Mean age was 53.4 years (range, 37 to 94). The Dermatophagoides mix was the most common allergen in the standard tray to evoke a reaction. At 96 hours, positive reactions were noted in 55% of patients. The reactions were interpreted as irritant in 16.2%, relevant in 6.7%, of questionable relevancy in 30.5%, and of no relevancy in 32.6%. The majority of reactions were of the [ldquo ]crescendo[rdquo ] pattern. Conclusion: The currently available formulation of Dermatophagoides mix, even at its lower concentration, led to a high rate of reactivity with a low rate of relevance.

背景:尘螨抗原致皮屑在引起或延续特应性皮炎和其他形式皮炎,特别是空气传播接触性皮炎中的作用一直存在争议。对类皮肤药物的反应性已通过特异性IgE和对点刺试验的立即型反应来测定。最近,斑贴试验已被提倡作为一种手段,以确定对类皮肤药物的反应性。目的:确定在接受贴片试验的人群中对一种去皮药混合物的反应性。方法:最近市售的2种皮蛾,翼状皮蛾和粉状皮蛾的混合物。作者选择了较低的有效浓度(20%),并在1999年12月至2001年1月期间将其添加到标准斑贴试验托盘中。结果按标准方式解释。结果:共有662例患者接受了皮肤癣药的贴片试验(男性32%,女性68%)。平均年龄53.4岁(37 ~ 94岁)。在标准托盘中,最常引起反应的过敏原是Dermatophagoides混合物。96小时时,55%的患者出现阳性反应。这些反应被解释为刺激性的占16.2%,相关的占6.7%,相关性可疑的占30.5%,无相关性的占32.6%。大多数反应呈渐强模式。结论:目前已有的复方药,即使在较低的浓度下,也具有较高的反应率和较低的相关性。
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引用次数: 12
CONTACT ALLERGIC LICHENOID ERUPTION TO PALLADIUM AND GOLD: 23 接触性过敏性地衣样疹对钯和金:23
Pub Date : 2002-06-01 DOI: 10.1097/01206501-200206000-00035
El-Azhary A. Rokea, R. Lund
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引用次数: 0
WATER SORPTION-DESORPTION TEST AND MOISTURE ACCUMULATION TEST FOR THE FUNCTIONAL ASSESSMENT OF ATOPIC SKIN IN CHILDREN: 32 32 .儿童特应性皮肤功能评价的吸解吸试验和水分积累试验
Pub Date : 2002-06-01 DOI: 10.1097/01206501-200206000-00044
G. Pellacani, S. Seidenari
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引用次数: 0
INTERACTIONS OF IRRITANTS - A NEW APPROACH TO IRRITANT CONTACT DERMATITIS: 25 刺激物的相互作用——一种治疗刺激性接触性皮炎的新方法:25
Pub Date : 2002-06-01 DOI: 10.1097/01206501-200206000-00037
P. Elsner, W. Wigger-alberti, A. Krebs, N. Goeritz, J. Spoo, U. Kappes
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引用次数: 0
CUTANEOUS COMPLAINTS & EXPOSURE FACTORS IN DENTAL STUDENTS: 7 牙科学生皮肤疾病及暴露因素:7
Pub Date : 2002-06-01 DOI: 10.1097/01206501-200206000-00019
J. Saary, S. Tarlo, L. Holness
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引用次数: 0
THE EFFECT OF RACE AND ETHNICITY ON PATCH TEST RESULTS FROM THE NORTH AMERICAN CONTACT DERMATITIS GROUP 1992–1998.: 24 种族和民族对1992-1998年北美接触性皮炎组斑贴试验结果的影响。: 24
Pub Date : 2002-06-01 DOI: 10.1097/01206501-200206000-00036
V. Deleo, Susan C. Taylor
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引用次数: 0
CONTACT SENSITIZATION TO DISPERSE DYES IN CHILDREN: 14 儿童对分散染料的接触致敏:14
Pub Date : 2002-06-01 DOI: 10.1097/01206501-200206000-00026
F. Giusti, Federica Massone, F. Neri, S. Seidenari
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引用次数: 0
DERMATITIS IN NURSES AT A MAJOR PUBLIC HOSPITAL IN MELBOURNE: 31 墨尔本一家大型公立医院护士的皮炎:31
Pub Date : 2002-06-01 DOI: 10.1097/01206501-200206000-00043
R. Nixon, Adriene Lee, K. Frowen
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引用次数: 0
期刊
American Journal of Contact Dermatitis
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