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Changes in the weight of internal organs in the fetal ontogenesis. 胎儿个体发育过程中内脏重量的变化。
Pub Date : 1989-05-03 DOI: 10.1127/ZMA/77/1989/235
B. Marecki
The purpose of this work was the investigation of the development of the weight of brain, heart, lungs, liver, spleen, kidneys, adrenal glands and thymus, and the developmental relations occurring between them in human fetuses and newborns. The material covering 1908 individuals of both sexes (632 fetuses and 1276 newborns) was collected in the Department of Pathological Anatomy in Poznań. During clinical autopsies the weight of organs was determined exactly to 0.1 g and the body weight exactly to 5 g. The age of the individuals was determined on the basis of the mean conception time (14-15 day after the beginning of the last menses) and it ranged from 17 to 43 weeks of gestation. The material was divided into 7 developmental periods. The first 6 periods cover the moon months successively from the 5th to the 10th and the last period covers the three final weeks (41-43). The problems were analysed on the basis of a comprehensive statistical analysis and the obtained results of the significant statistical dependences between the organs were confronted with the biological changes of the investigated features taking place in the period of fetal ontogenesis.
这项工作的目的是研究人类胎儿和新生儿脑、心、肺、肝、脾、肾、肾上腺和胸腺的重量发育,以及它们之间的发育关系。在波兹纳斯的病理解剖部门收集了1908个两性个体(632个胎儿和1276个新生儿)的资料。在临床解剖中,器官重量精确测定到0.1 g,体重精确测定到5 g。个体的年龄根据平均受孕时间(最后一次月经开始后14-15天)确定,其范围为妊娠17至43周。材料分为7个发育期。前6个周期依次为5日至10日的月亮月,最后一个周期为最后三个星期(41-43)。在综合统计分析的基础上对问题进行了分析,得到的器官之间显著的统计依赖性结果与所研究的特征在胎儿个体发生期间发生的生物学变化相对应。
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引用次数: 3
Genetic studies in four populations of the northern Aegean Sea, Greece. 希腊爱琴海北部四个种群的基因研究。
R Schliwa, A Dannewitz, K Gilbert, H Walter

A total of 945 non-related individuals from four isolated population groups from the Northern Aegean Sea (Greece)--Alonissos, Oxilithos, Skopelos, and Glossa, has been typed for 16 polymorphic systems of the blood, namely A1A2B0, MNS., Rhesus (C, c, Cw, D, E, e), Kell, Duffy (a,b), Kidd (a); Hp, Tf subtypes, Gc, Gm (1, 2, 3, 5, 13), Km (1); aP, AK, PGM1, EsD, and 6-PGD. The distribution of phenotype and gene/haplotype frequencies shows a considerable interpopulational variability, which is discussed considering the history of these populations as well as the impact of locally acting microevolutionary factors such as drift and founder effects. The average coefficient of gene diversity GST comes to 0.0147, whereas Wahlund's variance is on average 0.0154, and Wright's Fst = 0.0147. Genetic distance analysis reveals a pattern of similarities, which is in conformity with the history of the populations under study.

对来自爱琴海北部(希腊)四个孤立人群(Alonissos、Oxilithos、Skopelos和Glossa)的945名无亲缘关系个体进行了16种血液多态性系统的分型,即A1A2B0、MNS。, rheus (C, C, Cw, D, E, E), Kell, Duffy (a,b), Kidd (a);Hp、Tf亚型、Gc、Gm(1、2、3、5、13)、Km (1);aP, AK, PGM1, EsD和6-PGD。表型和基因/单倍型频率的分布显示出相当大的种群间变异性,考虑到这些种群的历史以及局部作用的微进化因素(如漂移和建立者效应)的影响,讨论了这一点。基因多样性系数GST平均为0.0147,Wahlund的方差平均为0.0154,Wright的Fst = 0.0147。遗传距离分析揭示了一种相似模式,这与所研究群体的历史一致。
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引用次数: 0
Causes of infant mortality in the Middle Ages revealed by chemical and palaeopathological analyses of skeletal remains. 通过骨骼残骸的化学和古病理学分析揭示了中世纪婴儿死亡的原因。
G Hühne-Osterloh, G Grupe

In most prehistoric and historic populations, mortality of small infants is very high. Causes of death are mainly discussed in analogy to the situation in modern preindustrial societies. The children are at high risk to fall ill or even die especially in times of weaning. Trace element analysis of the skeletal remains of small infants excavated in Schleswig (northern Germany, 11th/12th century AD) led to the estimation of weaning age as well as to the reconstruction of a stepwise substitution of mothers' milk by other food items. Subsequent palaeopathological analysis confirmed high mortality in this age-group. Thus, causes of death of small infants in a medieval town can be outlined.

在大多数史前和历史上的人口中,小婴儿的死亡率非常高。死亡原因的讨论主要类比于现代前工业社会的情况。这些孩子生病甚至死亡的风险很高,尤其是在断奶的时候。对石勒苏益格(德国北部,公元11 /12世纪)出土的小婴儿骨骼遗骸进行微量元素分析,得出了断奶年龄的估计,并重建了母乳被其他食物逐步替代的过程。随后的古病理学分析证实了该年龄组的高死亡率。因此,可以概述中世纪城镇中小婴儿死亡的原因。
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引用次数: 0
Lightmicroscopical investigations of the sublingua of Microcebus murinus (Cheirogaleidae, Lemuriformes) with remarks on the phylogenetic relations of the tree shrews (Scandentia) to primates. 鼠小头猴舌下部的光镜观察及树鼩与灵长类的系统发育关系。
H O Hofer

The sublingua of Microcebus murinus was studied gross anatomically and light microscopically. The apex of the sublingua ends in two lobe-like projections separated by a distinct median cleft. The lobes exhibit at their oral, free margin tiny processes, but no "comb"-like specializations of intensely keratinized mucosa. At the ventral surface of the sublingua three longitudinally oriented keels or ridges are found; the mucosa of the keels is strongly keratinized, so that these structures maximize the rigidity of the undertongue. In none of the specimens examined was any trace of sublingual cartilage found; in the sublingua of Cheirogaleus (only one individual examined), the nearest relative of Microcebus, cartilage was also absent. The absence of sublingual cartilage and the incidental, irregular occurrence of cartilaginous elements in the sublingua of Tarsius and Tupaia indicate that the sublingual cartilaginous skeleton is not a derivative of the hyoid arch. It is a newly developed supporting structure which does not regularly occur. A sublingua occurs only in prosimians and Tarsius; whether the fimbria linguae of the Hominoidea is the homologue of a sublingua is still disputable. The exclusive occurrence of a sublingua in prosimians and Tarsius indicates a phylogenetic relationship between these two groups and Tupaia. The "Tupaia-problem" concerns the origin of primates and from this point it derives its general importance. At present we are far from a final solution; a definite answer cannot be expected before sufficient fossil records are available which document conclusively the historical paths of the origin of primates.

对小头舌下进行了大体解剖和光镜观察。舌下嵴的顶端有两个叶状突起,中间有明显的间隙隔开。裂片在口腔自由缘处有微小突起,但没有强烈角化粘膜的“梳状”特化。在舌下的腹面有三个纵向的龙骨或脊;龙骨的粘膜是强烈角化的,因此这些结构使舌下的硬度最大化。在所有被检查的标本中都没有发现舌下软骨的痕迹;在与Microcebus最近的近亲Cheirogaleus的舌下(只检查了一个个体),软骨也缺失。舌下软骨的缺失以及Tarsius和Tupaia舌下软骨元素的偶然、不规则出现表明舌下软骨骨骼不是舌骨弓的衍生物。它是一种新发展起来的不经常出现的支撑结构。舌下舌只出现在前猴和跗猴;类人猿总科的缘状语言是否与舌下语言同系物仍有争议。舌下舌在原猴和塔修斯的独家出现表明这两个群体与图帕亚人之间存在系统发育关系。“图帕亚问题”涉及灵长类动物的起源,从这一点出发,它具有普遍的重要性。目前我们离最终解决方案还很远;要想得到一个明确的答案,还需要有足够的化石记录来证明灵长类动物起源的历史路径。
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引用次数: 0
Changes in the weight of internal organs in the fetal ontogenesis. 胎儿个体发育过程中内脏重量的变化。
B Marecki

The purpose of this work was the investigation of the development of the weight of brain, heart, lungs, liver, spleen, kidneys, adrenal glands and thymus, and the developmental relations occurring between them in human fetuses and newborns. The material covering 1908 individuals of both sexes (632 fetuses and 1276 newborns) was collected in the Department of Pathological Anatomy in Poznań. During clinical autopsies the weight of organs was determined exactly to 0.1 g and the body weight exactly to 5 g. The age of the individuals was determined on the basis of the mean conception time (14-15 day after the beginning of the last menses) and it ranged from 17 to 43 weeks of gestation. The material was divided into 7 developmental periods. The first 6 periods cover the moon months successively from the 5th to the 10th and the last period covers the three final weeks (41-43). The problems were analysed on the basis of a comprehensive statistical analysis and the obtained results of the significant statistical dependences between the organs were confronted with the biological changes of the investigated features taking place in the period of fetal ontogenesis.

这项工作的目的是研究人类胎儿和新生儿脑、心、肺、肝、脾、肾、肾上腺和胸腺的重量发育,以及它们之间的发育关系。在波兹纳斯的病理解剖部门收集了1908个两性个体(632个胎儿和1276个新生儿)的资料。在临床解剖中,器官重量精确测定到0.1 g,体重精确测定到5 g。个体的年龄根据平均受孕时间(最后一次月经开始后14-15天)确定,其范围为妊娠17至43周。材料分为7个发育期。前6个周期依次为5日至10日的月亮月,最后一个周期为最后三个星期(41-43)。在综合统计分析的基础上对问题进行了分析,得到的器官之间显著的统计依赖性结果与所研究的特征在胎儿个体发生期间发生的生物学变化相对应。
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引用次数: 0
Developmental relations between the weight of internal organs and somatic features of fetuses and newborns. 胎儿和新生儿内脏重量与躯体特征的发育关系。
B Marecki

The paper contains results of investigations on statistical developmental interrelations between the weight of brain, heart, lungs, liver, spleen, kidneys, adrenal glands and thymus, and the total length, the crown-rump length and the body weight, and the circumference of head, shoulders, chest and abdomen of fetuses and newborns in the age from 17 to 43 weeks of life. The character and the force of the relations between the degree of the development of the weight of organs and the body dimensions was investigated by statistical methods on three levels. On the basis of the value of linear correlation coefficients, statistical relations were determined between the weight of the particular organs and the particular sometic features. The dependence between the particular organs and the complex of somatic features was determined on the basis on the multiple regression analysis. On the other hand the relation between two complexes of features, i.e. all organs and all somatic features was investigated with the help of canonical correlation coefficients. The analysis of results indicated that between the weight of internal organs and the somatic features in the fetal period there exists a statistical developmental relation. The developmental relations are most strongly marked between the 6th and the 10th months of intrauterine life, while in the 5th month of life and in postmature fetuses and newborns they are weaker.

本文研究了17 ~ 43周龄胎儿和新生儿脑、心、肺、肝、脾、肾、肾上腺、胸腺的重量与总身长、冠臀长、体重、头、肩、胸、腹围的统计发育相互关系。用统计方法在三个层次上研究了器官重量的发育程度与身体尺寸之间的关系的特点和作用。根据线性相关系数的值,确定特定器官的重量与特定某些特征之间的统计关系。在多元回归分析的基础上,确定了特定器官与躯体特征复合体之间的相关性。另一方面,利用典型相关系数研究了两种特征复合体(即所有器官和所有躯体特征)之间的关系。结果表明,胎儿期内脏重量与躯体特征之间存在统计学上的发育关系。发育关系在宫内生命的第6个月和第10个月之间最为明显,而在生命的第5个月以及成熟后的胎儿和新生儿中,这种关系较弱。
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引用次数: 0
[Graphic normality test in human paleontology]. [人类古生物学图形正态性检验]。
A Leguebe, A Albert

In human palaeontology, samples are generally collections of objects gathered according to morphological criteria and their statistical analysis usually calls for caution because of the relatively small number of objects. Testing normality for such samples is a critical problem. The procedure suggested by Filliben, however, is particularly suitable for small to moderate sample sizes. Moreover, it provides a graphical presentation of the data that permits to locate each object within the distribution range. We briefly review the principle of the method and give a computer program to carry out the necessary computations and plot. Finally, we illustrate the method by studying the distribution of the maximum length and the maximum breadth for a sample of skulls of the Upper Palaeolithic.

在人类古生物学中,样本通常是根据形态学标准收集的物体的集合,由于样本数量相对较少,对样本的统计分析通常需要谨慎。检验这些样本的正态性是一个关键问题。然而,Filliben建议的程序特别适用于小到中等样本量。此外,它还提供了数据的图形表示,允许在分布范围内定位每个对象。我们简要回顾了该方法的原理,并给出了一个计算机程序来进行必要的计算和绘图。最后,我们通过研究旧石器时代晚期颅骨样本的最大长度和最大宽度的分布来说明该方法。
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引用次数: 0
[The problems of odontogenic kinship analysis in prehistoric anthropology in the example of aplasia/hypodontia]. [以发育不全/下颌畸形为例的史前人类学牙源性亲属分析问题]。
K W Alt

Prehistorians have been seeking information about kinship in burial complexes for decades. During the last few years paleoanthropologists have once again applied themselves to the resolution of that problem. Many of them favour epigenetic variants as the basis for their kinship analyses. Teeth and maxillary bones seem well suited to be investigated in view to this question. The author discusses whether hypodontia and numerical variants of teeth still meet the criteria demanded of epigenetic variants today. Using the complex odontological feature of hypodontia and its variants as a model, the article shows that by including and interpreting new and little-known facts the amount of information gained from this feature can be increased considerably, as can its value towards kinship analysis. More odontological features have to be added and suitable methods have to be developed. The employment of odontological features for kinship analyses is then likely to be a success.

几十年来,史前学家一直在墓葬群中寻找有关亲属关系的信息。在过去的几年里,古人类学家再次致力于解决这个问题。他们中的许多人倾向于将表观遗传变异作为亲属关系分析的基础。牙齿和上颌骨似乎很适合研究这个问题。作者讨论了牙齿的下颌缺损和数字变异是否仍然符合今天表观遗传变异的标准。本文以下颌畸形及其变体的复杂牙科学特征为模型,表明通过包括和解释新的和鲜为人知的事实,可以大大增加从这一特征中获得的信息量,也可以增加其对亲属关系分析的价值。必须增加更多的齿科特征,并开发合适的方法。利用牙学特征进行亲属关系分析很可能会取得成功。
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引用次数: 0
Incremental lines in prehistoric cremated teeth. A technical note. 史前火化牙齿的渐进式纹路。一个技术说明。
B Grosskopf

Incremental lines have been examined in cementum of modern human teeth. Their number is related to age. These lines are demonstrated in cremated teeth too and offer an additional feature for age determination in cremations.

在现代人类的牙骨质中发现了渐进式纹路。它们的数量与年龄有关。这些线条在火化的牙齿中也得到了证明,并为火化中的年龄测定提供了额外的功能。
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引用次数: 0
Standards of morphological development in fetuses and newborns as a method of defining fetal age. 胎儿和新生儿形态发育标准作为确定胎龄的方法。
K Cieślik

Whenever the calendar age of the studied fetal material is not known we are bound to reconstruct it by replacing it with the developmental age. In this paper some common developmental standards used in the determination of fetal age are reviewed. The standards, as found in the relevant literature, are tested against a control group for their accuracy in predicting fetal age. The results indicate considerable discrepancy among the various standards. Further, the developmental ages defined by these standards often differ considerably from the known menstrual age. My own attempt to present a more reliable set of developmental standards is based on the analysis of three morphological features commonly used in biological assessment. Body weight, crown-heel length, and crown-rump length are measured in weekly termed groups representing the 20th-42nd weeks of intrauterine life. The accuracy of body weight and crown-heel length in predicting fetal age is tested both within and against a control group. Statistical analysis show no significant differences between the predicted and known fetal ages. These results indicate that body weight and crown-heel length are reliable developmental standards from which fetal age can be defined.

每当所研究的胎儿材料的日历年龄未知时,我们必须通过用发育年龄代替它来重建它。本文综述了几种常用的胎儿年龄测定标准。这些标准,如在相关文献中发现的,在预测胎儿年龄的准确性方面与对照组进行了测试。结果表明,各种标准之间存在相当大的差异。此外,这些标准所定义的发育年龄往往与已知的月经年龄相差很大。我自己试图提出一套更可靠的发育标准,是基于对生物学评估中常用的三种形态特征的分析。体重、冠跟长度和冠臀长度以周为单位测量,代表子宫内生命的第20 -42周。体重和冠跟长度预测胎龄的准确性在对照组内和对照中进行了测试。统计分析显示,预测胎龄与已知胎龄之间无显著差异。这些结果表明,体重和冠跟长度是确定胎龄的可靠发育标准。
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引用次数: 0
期刊
Zeitschrift fur Morphologie und Anthropologie
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