Indian journal of malariology最新文献

Fortnightly application of Bacillus sphaericus (strain B101, serotype H5a5b) and B. thuringiensis var. israelensis (strain 164, serotype H-14) in two different waterways of Chennai @ 1 g/sq m surface area has resulted in significant reduction in both immature and adult densities of Culex quinquefasciatus Say. The use of these biolarvicides as biocontrol agents is suggested in the urban areas to control mosquitoes in general.

In-vitro and in-vivo susceptibility of Plasmodium falciparum to chloroquine were conducted at Chennai city, India. Eighteen (60%) out of 30 cases showed resistance in in-vitro study. EC50 of resistant and sensitive cases were 0.40 and 0.24 mumol chloroquine/l blood respectively, while EC90 were 2.64 and 0.84 mumol chloroquine/l blood respectively. In-vivo tests identified 24 cases (40%) as resistant (23 RI and 1 RII) and 36 (60%) as sensitive out of 60 cases. Eight isolates which were found resistant with in-vitro tests showed sensitive behaviour to chloroquine treatment assessed by in-vivo studies.

During a longitudinal study in the deciduous monsoon forest in northwest Orissa, 16 species belonging to Genera Anopheles (2), Culex (3), Aedes (8), Armigeres (1), Orthopodomyia (1) and Toxorhynchites (1) were found breeding in the treeholes, while 20 species including disease vectors An. culicifacies, Cx. quinquefasciatus, Ae. albopictus, Cx. tritaeniorhynchus and Cx. vishnui were found resting. The study showed that so far malaria vectors have not exploited the breeding potential of treeholes but Aedes albopictus, vector of dengue/ dengue haemorrhagic fever in Asia, was one of the main species breeding and resting in the treeholes. The paper describes seasonality, interspecific association and some new species breeding/resting in treeholes in Orissa.

The effect of malaria parasitaemia on spleen size and anaemia in 1,905 pregnant women in Jos Plateau highlands, Bauchi Savannah plains and Ethiope river basin of Nigeria was evaluated. The overall spleen rates in Jos Plateau, Bauchi and Ethiope were 15, 23, 16.33 and 10.71% respectively. Higher cases of palpable spleen were detected in pregnant women than non-pregnant controls. Spleen rates also showed seasonal variation, but not very significant. Malaria prevalence rates were higher than spleen rates. In all three study sites, parasitaemic pregnant women had significantly lower haemoglobin values than malaria negative mothers, especially among primigravids. However, there was no constant association between higher parasite density and splenomegaly, since few cases of enlarged spleens were also recorded among subjects with low parasitaemia. Severe anaemia was predominant among parasitaemic pregnant women with high spleen classes.

Study on the socio-cultural factors and economic loss due to malaria in rural and urban areas of Kheda district, Gujarat revealed that factors such as education, profession, income, housing pattern, social groups, water storage and treatment seeking behaviour play an important role in malaria transmission. However, the difference of these components in respect to malaria cases between rural and urban areas were statistically insignificant. Mean monetary loss per malaria episode was found to be more in urban area (Rs. 393.59) as compared to rural (Rs. 157.59). The study also suggests the importance of socio-cultural factors in implementing any community health programme. Health education is needed to make the people aware and health conscious for prevention of disease at their own level.

The field tests of combined use of Romanomermis yunanensis 2000-3000 larvae per sq m and Romanomermis sp 1000-2000 larvae per sq m in rice fields. Ponds and streams in four cities of China, resulted in 60.8-95.5% parasitism in Culex tritaeniorhynchus, Cx. quinquefasciatus, Anopheles sinensis and An. anthropophagus. This successful use of two species of Romanomermis together not only curb mosquito nuisance it also controls the major vectors of malaria, filariasis and encephalitis B in China.

A total of 41,552 anophelines comprising 16 species were collected during 70 all-night bovine-bait collection carried out in six villages of Kheda district, Gujarat. Anopheles subpictus, An. varuna, An. culicifacies, An. stephensi and An. vagus had unimodal biting rhythms. Most feeding occurred during the early night with occasional increase during pre-dawn/dawn hours. An. pallidus exhibited bimodal biting rhythm with two well-defined peaks. An. turkhudi, An. tessellatus, An. fluviatilis, An. aconitus, An. annularis; An. barbirostris and An. nigerrimus had multimodal biting rhythms or were arthymic. An. culicifacies, An. varuna, An. aconitus and An. tessellatus exhibited a marked seasonal shift in feeding activities with most biting occurring at dusk in colder months and late at night during warmer months.