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[Platelet Concentrates - Indication, Informed Consent, Transfusion and Adverse Events]. [血小板浓缩物-适应症,知情同意,输血和不良事件]。
IF 0.3 4区 医学 Q4 ANESTHESIOLOGY Pub Date : 2025-01-01 Epub Date: 2025-01-08 DOI: 10.1055/a-2234-1341
Markus M Müller, Maximilian Lehmann, Vanessa Neef, Kai Zacharowski, Torsten Tonn

Transfusion of platelet concentrates (PC) can be a life-saving measure in case of severe thrombocytopenia or thrombocytopathy, particularly in bleeding patients. Although acaryote, platelets are involved in several important functions including immunomodulation, but their most important function is in primary and secondary haemostasis. In this German review, apheresis and whole blood derived PC are compared and indications as well as transfusion triggers and dosage of PC are discussed. Apart from emergencies, transfusion of PC can only occur after informed consent. Therefore, the treating physician should be aware of the potential adverse events and their prophylaxis in order to best advise the patient. Eight of the most prevalent and/or clinically severe adverse events following PC transfusion and their handling and prevention are discussed. In addition, practical aspects of PC transfusion are depicted as well as the treating physician's choice of the appropriate PC including a flowchart for refractory patients.

在严重血小板减少症或血小板病变的情况下,输血浓缩血小板(PC)可以是一种挽救生命的措施,特别是在出血患者中。血小板虽无核细胞,但其最重要的功能是原发性和继发性止血。在这篇德国的综述中,比较了单采和全血来源的PC,并讨论了PC的适应症以及输血触发因素和剂量。除紧急情况外,只有在知情同意的情况下才能输血。因此,治疗医师应了解潜在的不良事件及其预防措施,以便为患者提供最佳建议。本文讨论了PC输血后最常见和/或临床上最严重的8个不良事件及其处理和预防。此外,还描述了PC输血的实际方面以及治疗医生对适当PC的选择,包括难治性患者的流程图。
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引用次数: 0
[Thoracoabdominal Trauma Caused by Blast and Gunshot Injuries]. [爆炸和枪伤造成的胸腹部创伤]。
IF 0.3 4区 医学 Q4 ANESTHESIOLOGY Pub Date : 2024-11-01 Epub Date: 2024-11-21 DOI: 10.1055/a-2176-3872
Angelina Klein, Sebastian Schaaf, Christoph Güsgen

In Germany, blast and gunshot injuries are uncommon but complex injury entities. Due to the global political situation, terrorist attacks, accidents, or acts of violence, these injuries are potentially part of the reality of care for every anaesthetist, surgeon, and emergency physician. In principle, this type of injury should be treated in a trauma centre with appropriate expertise, but the knowledge of basic treatment principles is necessary for all practitioners. First, emergency training and surgical simulation courses should be carried out regularly to remain confident in emergency surgery techniques and treatment strategies. In addition, minimally invasive methods are predominantly used in elective surgery, meaning that the routine of primarily open surgery is missing. Therefore, it is important that surgeons learn surgical steps to be better prepared for emergency open surgery.The critical principle of damage control surgery is stopping the bleeding and the contamination and preventing a delay in intensive care therapy. For penetrating thoracic trauma, a chest tube must be inserted. If the patient is hemodynamically unstable, an anterolateral thoracotomy should be performed to achieve bleeding control, e.g., by cross-clamping the aorta or pulmonary hilum. For stable patients, a video-assisted thoracoscopy might be an option.The standard abdominal approach is the median laparotomy. Bleeding control can be achieved by hiatal aortic cross-clamping and packing of the abdomen, followed by a systematic exploration. If necessary, a laparostomy must be established. Moreover, if chest injuries are ruled out, the resuscitative endovascular balloon occlusion of the aorta (REBOA) can be considered as a bridge to surgery.Whether projectiles, fragments, or shrapnels require removal depends on the location and the potential complications of tissue dissection. Penetrating injuries due to blasts and gunshots are always contaminated.

在德国,爆炸伤和枪伤并不常见,但却是一种复杂的伤害。由于全球政治局势、恐怖袭击、意外事故或暴力行为等原因,这些伤害有可能成为每一位麻醉师、外科医生和急诊科医生现实工作中的一部分。原则上,这类损伤应在具备相应专业知识的创伤中心进行治疗,但所有从业人员都必须掌握基本的治疗原则。首先,应定期开展急诊培训和手术模拟课程,以保持对急诊手术技术和治疗策略的信心。此外,微创方法主要用于择期手术,这意味着以开放手术为主的常规手术已不复存在。因此,外科医生必须学习手术步骤,为急诊开放手术做好更充分的准备。损害控制手术的关键原则是止血和止血污染,防止延误重症监护治疗。对于穿透性胸部创伤,必须插入胸管。如果患者血流动力学不稳定,应进行前外侧开胸手术以控制出血,例如通过交叉夹闭主动脉或肺门。对于病情稳定的患者,可以选择视频辅助胸腔镜手术。通过食管裂孔主动脉交叉钳夹术和腹部填塞术控制出血,然后进行系统性探查。如有必要,必须建立腹腔造口术。此外,如果排除了胸部受伤的可能性,则可以考虑使用主动脉血管内球囊闭塞术(REBOA)作为手术的过渡。是否需要取出弹丸、碎片或弹片取决于组织剥离的位置和潜在并发症。爆炸和枪击造成的穿透伤总是受到污染。
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引用次数: 0
[The Penny's Dropped - "Aha" Moments in Emergency Medicine Diagnostics]. [一分钱没了--急诊医学诊断中的 "啊哈 "时刻】。]
IF 0.3 4区 医学 Q4 ANESTHESIOLOGY Pub Date : 2024-11-01 Epub Date: 2024-11-21 DOI: 10.1055/a-2363-8039
Christian Engelen, Rebecca Junker, Klaus Fessele, Rüdiger Lange

Hardly any other speciality is as fraught with tension as emergency medicine. In addition to the need to have a broad spectrum of knowledge about illnesses and injuries, the time factor is particularly important. Emergency physicians have to quickly gain an overview of their patients' condition. Mostly without having all the information about the patient's medical history, long-term medication or previous findings. Decisions have to be made under time pressure. In addition to experience and knowledge, the targeted use of the available diagnostic options is essential for quick treatment decisions. A detective-like approach is sometimes required here, particularly in order to confirm suspected diagnoses and rule out differential diagnoses by using focussed diagnostics. Clinical experience, training and the odd "trick" lay the foundation for skillfully using the diagnostic options at the right time for the right patient - i.e. point-of-care - and finding the right diagnosis. Aha!

几乎没有任何其他专业能像急诊医学一样充满紧张气氛。除了需要掌握有关疾病和伤害的广泛知识外,时间因素也尤为重要。急诊医生必须迅速了解病人的病情。在大多数情况下,他们并不掌握病人的病史、长期用药或既往检查结果等所有信息。必须在时间压力下做出决定。除了经验和知识外,有针对性地使用现有诊断方案对于快速做出治疗决定也至关重要。有时需要采取侦探式的方法,特别是通过重点诊断来确认疑似诊断和排除鉴别诊断。临床经验、培训和奇特的 "窍门 "为在正确的时间对正确的病人(即护理点)熟练使用诊断选项并找到正确的诊断奠定了基础。啊哈
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引用次数: 0
Schusswaffen- und Explosionsverletzungen. 枪伤和爆炸伤。
IF 0.3 4区 医学 Q4 ANESTHESIOLOGY Pub Date : 2024-11-01 Epub Date: 2024-11-21 DOI: 10.1055/a-2387-2781
Hinnerk Wulf
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引用次数: 0
[Gunshot and Blast Injuries from a Trauma Surgery Perspective]. [从创伤外科角度看枪伤和爆炸伤]。
IF 0.3 4区 医学 Q4 ANESTHESIOLOGY Pub Date : 2024-11-01 Epub Date: 2024-11-21 DOI: 10.1055/a-2176-3888
Catharina C Gäth, Dan Bieler, Sebastian Hentsch, Erwin Kollig, Florian Pavlu

The severity and extent of gunshot and blast injuries are often misjudged due to a lack of specialist knowledge. The aim of this article is to outline the characteristics of gunshot and blast injuries, including emergency diagnostics and initial surgical treatment.Due to multiple high-energy penetrating injuries, barotrauma, or blunt trauma, affected patients are usually polytraumatized, with multiple organ damage and an average Injury Severity Score (ISS) of > 36. In addition to the complexity of the wounds, they are characteristically severely contaminated. After pre-hospital treatment, life-threatening injuries and conditions should be identified and initially treated in the trauma room phase. The procedure should be based on a standardized, internal hospital emergency medical and emergency surgical algorithm. Damage control surgery can then be used to treat acutely life-threatening complications of gunshot and blast injuries in order to prevent the fatal triad and the occurrence of further early complications. Examples of interventions include debridement and decontamination, fracture stabilization (external fixators and splints), surgical decompression (skull, thorax, compartment syndromes) and surgical hemostasis.

由于缺乏专业知识,枪伤和爆炸伤的严重程度和范围常常被误判。本文旨在概述枪伤和爆炸伤的特点,包括急诊诊断和初始手术治疗。由于多处高能穿透伤、气压伤或钝器伤,受影响的患者通常会受到多处创伤,多器官受损,平均损伤严重程度评分(ISS)大于 36。除了伤口复杂外,他们还通常受到严重污染。在院前救治后,应在创伤室阶段识别并初步处理危及生命的伤情。治疗程序应基于标准化的医院内部急诊内科和急诊外科算法。损伤控制手术可用于治疗枪伤和爆炸伤的急性并发症,以防止致命的三联症和更多早期并发症的发生。干预措施包括清创和去污、骨折稳定(外固定器和夹板)、外科减压(颅骨、胸部、隔间综合症)和外科止血。
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引用次数: 0
[Preclinical Treatment of Gunshot and Blast Injuries in Germany]. [德国枪伤和爆炸伤的临床前治疗]。
IF 0.3 4区 医学 Q4 ANESTHESIOLOGY Pub Date : 2024-11-01 Epub Date: 2024-11-21 DOI: 10.1055/a-2412-3200
Jan-Henrik Rathjen, Martin Kulla, Axel Franke, Erwin Kollig, Dan Bieler

Gunshot and blast injuries are extremely rare in the emergency services. However, in the context of the increasing threat of terrorist attacks, the possibility of these traumas is also coming into focus. This article provides an overview of the various entities and the corresponding treatment principles for penetrating injuries.

枪伤和爆炸伤在急救服务中极为罕见。然而,在恐怖袭击威胁日益加剧的背景下,这些创伤的可能性也逐渐成为人们关注的焦点。本文概述了穿透伤的各种实体和相应的治疗原则。
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引用次数: 0
[Reconciling Sustainability and Hygiene in the Healthcare Sector]. [兼顾医疗保健领域的可持续性和卫生]。
IF 0.3 4区 医学 Q4 ANESTHESIOLOGY Pub Date : 2024-11-01 Epub Date: 2024-11-21 DOI: 10.1055/a-2413-7408
Sebastian Schulz-Stübner, Mirjam Wolinski

In the course of climate change, doctors will not only be confronted with heat-related consequences, but also with the emergence of infectious diseases caused by previously tropical pathogens in temperate climate zones.Fortunately, the topics of sustainability and climate change are also becoming increasingly important in discussions in the healthcare sector, which accounts for 4.4% of global greenhouse gas emissions. The topic of hygienically safe sustainability in healthcare facilities is highly complex due to the large number of possible adjustments, but also offers a great deal of potential.Numerous measures can be implemented without any restrictions in terms of hygiene requirements or occupational safety.It is not always the large investments that make their contribution to reducing CO2-emissions - many smaller measures can also be implemented without high costs, but with great sustainability potential. Similar to hand hygiene compliance, behavior modification by each individual plays a decisive role in the implementation of such projects. There is great practical savings potential, for example, in the indication-based use of disposable medical gloves, the hygienically safe handling of medication or the decision between reusable and disposable medical products, just to name a few items discussed in the article.

在气候变化的过程中,医生不仅要面对与高温有关的后果,还要面对以前由热带病原体引起的传染病在温带气候区的出现。幸运的是,可持续发展和气候变化的话题在医疗保健行业的讨论中也变得越来越重要,该行业的温室气体排放量占全球的 4.4%。医疗卫生机构的卫生安全可持续发展话题由于可能的调整措施较多而变得非常复杂,但同时也具有很大的潜力。许多措施都可以在不受卫生要求或职业安全限制的情况下实施。与遵守手部卫生类似,每个人的行为改变在此类项目的实施中起着决定性作用。例如,在根据适应症使用一次性医用手套、以卫生安全的方式处理药物或决定使用可重复使用和一次性医疗产品等方面,都有很大的实际节约潜力。
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引用次数: 0
[Panta rhei - Everything Flows]. [Panta rhei - 万物流动]。
IF 0.3 4区 医学 Q4 ANESTHESIOLOGY Pub Date : 2024-10-01 Epub Date: 2024-10-11 DOI: 10.1055/a-2374-1418
Patrick Meybohm
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引用次数: 0
[Compulsory Training in Post-pandemic Times - Presence, Digital, Hybrid & Co. Using the Example of the University Hospital of Würzburg]. [后流行病时代的义务培训--存在、数字、混合与其他。以维尔茨堡大学医院为例]。
IF 0.3 4区 医学 Q4 ANESTHESIOLOGY Pub Date : 2024-10-01 Epub Date: 2024-10-11 DOI: 10.1055/a-2219-0024
Nils-Gerhard Eggers

With the end of the pandemic in April 2023 the whole learning environment had run through some major changes. The act of normal teaching was not that easy anymore during the pandemic. The size of a class had to be cut down to a size that fits the hygienic guidelines. Therefore, methods like blended learning and virtual classrooms came to life stronger than before. The methods were not new but never before needed in such a strong matter. Due to the experience with these methods of education, teaching and learning stayed different. Topics like virtual reality and even augmented reality stayed and are to some point part of the educational system nowadays. Due to the pandemic, it may seem that these new kinds of methods are worse compared to the ones we are used to but several studies can prove the opposite.The University Hospital Würzburg (UKW) has adapted to these kinds of changes. Every specialist training was formed to fit the necessary changes during the pandemic. It was not easy to keep up good practical education with the correct distance measurement, open windows for fresh air every 45 minutes or an FFP2 mask for protection. The rest of the close to 190 trainings held in the rooms of the academy of the UKW had to be cancelled or cut down to a group size allowed. Most of the known digital teaching and learning system that were installed at that time remained and are in use.

随着大流行病于 2023 年 4 月结束,整个学习环境发生了重大变化。在大流行期间,正常的教学行为不再那么容易。班级规模必须缩小到符合卫生准则的大小。因此,混合式学习和虚拟教室等方法比以前更有生命力。这些方法并不新鲜,但以前从未如此强烈地需要过。有了这些教育方法的经验,教与学就变得不同了。虚拟现实甚至是增强现实等主题一直存在,并在某种程度上成为当今教育系统的一部分。维尔茨堡大学医院(UKW)已经适应了这些变化。维尔茨堡大学医院(UKW)已经适应了这些变化。在大流行病期间,每项专业培训都是为了适应必要的变化而进行的。通过正确的距离测量、每 45 分钟开窗换气或佩戴 FFP2 防护口罩来保持良好的实践教育并非易事。在英国妇女协会学院的教室里举行的近 190 场培训中,其余的培训不得不取消或缩减到允许的小组规模。当时安装的大部分已知数字教学系统仍在使用。
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引用次数: 0
[Talking to Unconscious? - Therapeutic Communication During General Anaesthesia, Resuscitation and Therapy of Coma]. [与无意识者对话?- 全身麻醉、复苏和昏迷治疗期间的治疗性交流]。
IF 0.3 4区 医学 Q4 ANESTHESIOLOGY Pub Date : 2024-10-01 Epub Date: 2024-10-11 DOI: 10.1055/a-2046-4466
Nina Zech, Ernil Hansen

There are numerous reports from patients concerning perceptions during deep unconsciousness, be it general anaesthesia, cardiopulmonary resuscitation or intensive care and coma treatment. These experiences can cause considerable traumatisation. The most stressful experience is apparently not feeling pain, but the lack of communication, i.e. being recognised and being able to express oneself. Although there are already indications of positive effects of positive communication during general anaesthesia, these findings have not yet markedly changed the way we deal with the unconscious.

无论是全身麻醉、心肺复苏,还是重症监护和昏迷治疗,都有大量患者关于深度昏迷期间感知的报告。这些经历会造成相当大的心理创伤。最令人紧张的经历显然不是感到疼痛,而是缺乏交流,即被人认出和无法表达自己。尽管已经有迹象表明,在全身麻醉期间进行积极交流会产生积极影响,但这些发现尚未明显改变我们处理无意识状态的方式。
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引用次数: 0
期刊
Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie
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