首页 > 最新文献

Contemporary issues in clinical biochemistry最新文献

英文 中文
Enzyme electrodes and related technologies. 酶电极及其相关技术。
J C Weaver

The technical outlook is promising for miniature analytical systems which are internally complex but externally simple. Salient features to be anticipated are: The use of miniature electrodes or other sensors in combination with enzymes or immunological compounds for biochemical specificity. The use of arrays of miniature electrodes or other sensors. Relatively low cost because of adaptation of semiconductor fabrication techniques. The attendant possibility of the devices being disposable. The intimate involvement of real time computation. The use of simultaneous replicate assays, with increased confidence in the accuracy of the assay. Overall, rapid assays. Because of these possibilities, it may be concluded that the technological outlook for conducting clinical chemistry assays nearer the patient is promising.

内部复杂、外部简单的微型分析系统具有广阔的技术前景。值得期待的显著特征是:微型电极或其他传感器与酶或免疫化合物结合使用,用于生化特异性。微型电极阵列或其他传感器的使用。由于适应半导体制造技术,成本相对较低。随之而来的可能是设备是一次性的。实时计算的密切参与。同时重复测定的使用,增加了测定准确性的信心。总的来说,快速检测。由于这些可能性,可以得出结论,在离患者更近的地方进行临床化学分析的技术前景是有希望的。
{"title":"Enzyme electrodes and related technologies.","authors":"J C Weaver","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The technical outlook is promising for miniature analytical systems which are internally complex but externally simple. Salient features to be anticipated are: The use of miniature electrodes or other sensors in combination with enzymes or immunological compounds for biochemical specificity. The use of arrays of miniature electrodes or other sensors. Relatively low cost because of adaptation of semiconductor fabrication techniques. The attendant possibility of the devices being disposable. The intimate involvement of real time computation. The use of simultaneous replicate assays, with increased confidence in the accuracy of the assay. Overall, rapid assays. Because of these possibilities, it may be concluded that the technological outlook for conducting clinical chemistry assays nearer the patient is promising.</p>","PeriodicalId":77915,"journal":{"name":"Contemporary issues in clinical biochemistry","volume":"2 ","pages":"89-107"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14961625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biochemical self-monitoring: promise, practice and problems. 生化自我监测:前景、实践与问题。
S Walford, K G Alberti
{"title":"Biochemical self-monitoring: promise, practice and problems.","authors":"S Walford,&nbsp;K G Alberti","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77915,"journal":{"name":"Contemporary issues in clinical biochemistry","volume":"2 ","pages":"200-13"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14961617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digoxin. 地高辛。
J K Aronson
{"title":"Digoxin.","authors":"J K Aronson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77915,"journal":{"name":"Contemporary issues in clinical biochemistry","volume":"3 ","pages":"182-210"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15028489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organisation of a therapeutic drug monitoring service. 组织治疗药物监测服务。
G J Ayers, D Burnett
{"title":"Organisation of a therapeutic drug monitoring service.","authors":"G J Ayers,&nbsp;D Burnett","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77915,"journal":{"name":"Contemporary issues in clinical biochemistry","volume":"3 ","pages":"78-94"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14957716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical testing and quality control. 临床试验和质量控制。
D Kutter
{"title":"Clinical testing and quality control.","authors":"D Kutter","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77915,"journal":{"name":"Contemporary issues in clinical biochemistry","volume":"2 ","pages":"139-49"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14957890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic monitoring of antiarrhythmic drugs. 抗心律失常药物的治疗监测。
D W Holt
{"title":"Therapeutic monitoring of antiarrhythmic drugs.","authors":"D W Holt","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77915,"journal":{"name":"Contemporary issues in clinical biochemistry","volume":"3 ","pages":"154-81"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15028487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The tricyclic antidepressants. 三环抗抑郁药。
R A Braithwaite
{"title":"The tricyclic antidepressants.","authors":"R A Braithwaite","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77915,"journal":{"name":"Contemporary issues in clinical biochemistry","volume":"3 ","pages":"211-39"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15028490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selection of methods for therapeutic drug monitoring. 治疗药物监测方法的选择。
M J Stewart
{"title":"Selection of methods for therapeutic drug monitoring.","authors":"M J Stewart","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77915,"journal":{"name":"Contemporary issues in clinical biochemistry","volume":"3 ","pages":"61-77"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14957715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immediacy: speed of response from the point of view of the physician. 即时性:从医生的角度反应的速度。
G Sandler

A study has been carried out to determine the value of some standard biochemical tests in the emergency management of 209 acute medical admissions. Of the 678 emergency tests done, only 17.5 per cent showed abnormal results and of these only 12 per cent were helpful in diagnosis although 66 per cent were of value in treating the patients. The tests were most helpful in treating diabetic patients where the blood-glucose level decided insulin dosage in every patient; the pO2 and pCO2 levels were of value in acute on chronic obstructive airways disease; and the serum electrolytes were helpful in managing dehydration due to vomiting and diarrhoea. The possible reasons for the large number of useless tests carried out in diagnosis of these emergency admissions are discussed, and it is suggested that the most important way of avoiding unnecessary tests is better doctor training both before and after qualification. The place of immediacy of tests in the medical out-patient department is also considered. It is concluded that immediacy is of little value in diagnosing and treating out-patients, but would be helpful in reducing unnecessary return visits.

对209例急症住院病人进行了标准生化检查,以确定其在急诊管理中的价值。在进行的678次紧急检查中,只有17.5%显示异常结果,其中只有12%有助于诊断,尽管66%对治疗患者有价值。这些试验对治疗糖尿病患者最有帮助,因为血糖水平决定了每个患者的胰岛素剂量;pO2和pCO2水平对急性和慢性阻塞性气道疾病有价值;血清电解质有助于控制呕吐和腹泻引起的脱水。讨论了在急诊就诊诊断中进行大量无用检查的可能原因,并建议避免不必要检查的最重要方法是在获得资格之前和之后对医生进行更好的培训。还考虑了在医疗门诊部立即进行检查的地点。结论:即时性在门诊诊断和治疗中价值不大,但有助于减少不必要的复诊。
{"title":"Immediacy: speed of response from the point of view of the physician.","authors":"G Sandler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A study has been carried out to determine the value of some standard biochemical tests in the emergency management of 209 acute medical admissions. Of the 678 emergency tests done, only 17.5 per cent showed abnormal results and of these only 12 per cent were helpful in diagnosis although 66 per cent were of value in treating the patients. The tests were most helpful in treating diabetic patients where the blood-glucose level decided insulin dosage in every patient; the pO2 and pCO2 levels were of value in acute on chronic obstructive airways disease; and the serum electrolytes were helpful in managing dehydration due to vomiting and diarrhoea. The possible reasons for the large number of useless tests carried out in diagnosis of these emergency admissions are discussed, and it is suggested that the most important way of avoiding unnecessary tests is better doctor training both before and after qualification. The place of immediacy of tests in the medical out-patient department is also considered. It is concluded that immediacy is of little value in diagnosing and treating out-patients, but would be helpful in reducing unnecessary return visits.</p>","PeriodicalId":77915,"journal":{"name":"Contemporary issues in clinical biochemistry","volume":"2 ","pages":"38-51"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14961621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Liability: who carries the can? 责任:谁来承担责任?
N R Davidson
{"title":"Liability: who carries the can?","authors":"N R Davidson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77915,"journal":{"name":"Contemporary issues in clinical biochemistry","volume":"2 ","pages":"168-74"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14957892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Contemporary issues in clinical biochemistry
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1