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TREATMENT OF CHYLOTHORAX - ANESTHESIOLOGICAL OR SURGICAL PROBLEM?. 乳糜胸的治疗——麻醉还是手术?
Pub Date : 2017-01-01 DOI: 10.18821/0201-7563-2017-62-1-63-68
V. D. PRrhin, M. A. Vvzhiaina, A. A. Bunvatvan, A. Parshin, S. Zhukova
BACKGROUND The progress of surgery, the widespread use in the clinic of cardiac surgery and extended lymphadenectomy in thoracic surgery led to a greater incidence of the thoracic lymphatic duct ' trauma. That is why the actuality of treatment of chylothorax and chylorrhea is increased. The aim; improvement of diagnostics, prevention and treatment results ofpatients with chylothorax and chylorrhea. MATERIALS AND METHODS 37 patients (14 women and 23 men) with chylothorax had been treating with our participation in different hospitals from 2004 to 2014. The age of the patients was from 32 to 71 years. In 34 patients chylothorax occurred after surgery, in 3 patients - during the decompensation of the therapy diseases with the use of central venous catheterization, with an earlier clinic of thrombosis of the large veins of the neck. RESULTS Conservative therapy had good clinical effect of 83.8%. 1 patient died due to pneumonia of the single lung on the background of chylothorax developed in the postoperative period after right-sided pneumonectomy. In other cases, chylothorax was eliminated and in the late period had no recurrence. CONCLUSION prevention of chylothorax depends on the experience of the operating surgeon. If there is doubt intact thoracic lymphatic duct, it has tightened with the stitching surrounding adipose tissue. Conservative therapy is the method of choice in the treatment of chylothorax. Surgery is indicated for failure of conservative therapy within the first two weeks, or when massive chylorrhea takes place.
背景外科技术的进步、心脏外科临床的广泛应用以及胸外科淋巴结切除术的扩大,导致胸淋巴管损伤的发生率增加。这就是为什么治疗乳糜胸和乳糜漏的现状越来越多。目的;提高乳糜胸和乳糜溢的诊断、预防和治疗效果。材料与方法2004 - 2014年我院参与治疗的乳糜胸患者37例(女14例,男23例)。患者年龄32 ~ 71岁。34例患者术后发生乳糜胸,3例患者在治疗失代偿期间采用中心静脉置管,临床较早出现颈部大静脉血栓形成。结果保守治疗的临床有效率为83.8%。右侧全肺切除术后发生乳糜胸,因单侧肺肺炎死亡1例。在其他情况下,乳糜胸已消除,并在后期没有复发。结论乳糜胸的预防依赖于手术医师的经验。若怀疑胸淋巴管完好,则其已与脂肪组织周围的缝合处收紧。保守治疗是乳糜胸的首选治疗方法。在前两周内保守治疗失败或发生大量乳糜泻时,需要手术治疗。
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引用次数: 1
COMPARISON OF EMERGENCE AND RECOVERY CHARACTERISTICS OF SEVOFLURANE AND DESFLURANE IN PEDIATRIC AMBULATORY SURGERY. 七氟醚和地氟醚在儿科门诊手术中的出现和恢复特点比较。
Pub Date : 2017-01-01 DOI: 10.18821/0201-7563-2017-62-1-4-6
A. V. Lsakov, O. N. Paponov, E. G. Aaavelvan, S. M. Stenanenko
BACKGROUND A big number ofshort-time surgery performed in one-day pediatric department requires the permanent search of an ideal anesthetic for the maximum quickly children ' take home with the minimum ofpostoperation complications. THE AIM to compare the emergence and recovery characteristics ofsevoflurane and desflurane maintenance ofanesthe- sia in children undergoing ambulatory surgery. RESULTS AND CONCLUSION There were no significant differences among the two groups in hemodynamic parameters, the incidence of postoperative vomiting and cough. But desflurane maintenance of anesthesia resulted in the fastest early emergence from anesthesia, the lack of incidence ofpostoperative agitation compared with sevoflurane.
背景:在儿科进行的大量短期手术需要长期寻找一种理想的麻醉剂,以最大限度地快速将儿童带回家,并减少术后并发症。目的比较七氟醚和地氟醚维持麻醉对门诊手术患儿的出现和恢复特点。结果与结论两组患者在血流动力学参数、术后呕吐、咳嗽发生率方面无显著差异。但与七氟醚相比,地氟醚维持麻醉的早期苏醒最快,术后躁动发生率低。
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引用次数: 1
EXTRAVASCULAR LUNG WATER IS A PREDICTOR OF DEVELOPMENT OF MULTIPLE ORGAN FAILURE IN CHILDREN WITH SEVERE BURN INJURY. 肺血管外水是严重烧伤儿童多器官衰竭发展的一个预测指标。
Pub Date : 2017-01-01
A U Lekmanov, D K Azovskiy, S F Pilyutik, V M Abramova

The aim: to determine if an increased extravascular lung water level (EVLW) would be a predictor of multiple organ failure in pediatric patients with severe burn injury.

Materials and methods: a prospective study included 33 pediatric patients with burn surface from 30 to 90% of the total body surface area, admitted to PICU. All the patients were monitored with PICCO-technology advanced hemodynamic monitoring, that included an analysis ofEVLW level every 6 hours during first 48 hours after PICU admission.

Results: the diagnosis of multiple organ failure received according to DENVERII score. Normal values of weight indexed ELWI (extravascular lung water index)were 9-29 ml/kg for children under 1-year-oldage, 7-25 ml/kg for children from 1 to 5 years old and 5-13 ml/kg for children older than 5 years.

Conclusions: a normal value of height indexed ELWI was up to 315 ml/m. The height indexed ELWI level correlated reliably with multiple organ dysfunction syndrome rate in all time measurements. So ELWI can be used as a MOD prognostic factor There was no correlation between surface of burned skin and EVLW level.

目的:确定是否增加血管外肺水位(EVLW)将是多器官功能衰竭的一个预测因素,儿童严重烧伤患者。材料和方法:一项前瞻性研究纳入了33例PICU收治的烧伤表面占体表面积30%至90%的儿科患者。所有患者均采用picco技术进行高级血流动力学监测,包括PICU入院后48小时内每6小时evlw水平分析。结果:多脏器功能衰竭诊断依据DENVERII评分。1岁以下儿童体重指数ELWI(血管外肺水指数)正常值为9 ~ 29 ml/kg, 1 ~ 5岁儿童为7 ~ 25 ml/kg, 5岁以上儿童为5 ~ 13 ml/kg。结论:高度指数ELWI正常值为315 ml/m。在所有时间测量中,身高指数ELWI水平与多器官功能障碍综合征发生率可靠相关。因此,ELWI可作为MOD的预后因素。烧伤皮肤表面与EVLW水平无相关性。
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引用次数: 0
PREDICTION OF VARIOUS FORMS OF POSTOPERATIVE ACUTE LIVER FAILURE. 预测各种形式的术后急性肝衰竭。
Pub Date : 2017-01-01 DOI: 10.18821/0201-7563-2017-62-1-73-76
S. V. Sin'kov, I. V. Zhilin, I. Zabolotskikh
165 patients over 18 years in the period from January 2014 to March 2015 were studied. The aim was to investigate the prognostic significance of known scale assessment of organ dysfunction in respect ofpostoperative hepatic failure. The development of acute liver failure was assessed on the basis of clinical and laboratory data, severity of the condition by scales MELD, Child-Turcotte-Pugh, Maddrey, Schindl, BILE score, SOFA. The paper identified the incidence offorms of acute liver failure (hepatic encephalopathy, hepatic coagulopathy, hepatorenal syndrome, systemic hemodynamic disorder mixed form) in patients after surgery on hepatobiliary system, and the dependence of the probability of their occurrence on the severity of the condition, calculated using a scales in the preoperative period. Calculated sensitivity and specificity in predicting scales investigatedforms of acute liver failure based on ROC-analysis. It was shown that the specialized rating scales have good predictive accuracy in respect of certain forms of hepatic insufficiency (Child-Tur-cotte-Pugh -for hemodynamic options and hepatic coagulopathy, MELD and SOFA scales -for hepatic encephalopathy SCHINDL -for hepatorenal syndrome and mixed forms of hepatic failure). None of the analyzed scales do not possess predictive value with respect to all forms of hepatic failure.
研究对象为2014年1月至2015年3月,年龄在18岁以上的165例患者。目的是探讨已知脏器功能障碍评分对术后肝功能衰竭的预后意义。根据临床和实验室数据、MELD量表、child - turcote - pugh量表、Maddrey量表、Schindl量表、胆汁胆汁评分、SOFA量表评估急性肝衰竭的发展情况。本文确定了手术后患者急性肝功能衰竭(肝性脑病、肝凝血功能障碍、肝肾综合征、全身血流动力学紊乱混合形式)在肝胆系统的发生率,以及术前使用a量表计算其发生概率与病情严重程度的依赖关系。基于roc分析的急性肝衰竭预测量表的计算敏感性和特异性。研究表明,对于某些形式的肝功能不全(child - turt -cotte- pugh -用于血流动力学选项和肝凝血病,MELD和SOFA量表-用于肝性脑病,SCHINDL -用于肝肾综合征和混合形式的肝功能衰竭),专业评分量表具有良好的预测准确性。所有分析的量表都对所有形式的肝衰竭具有预测价值。
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引用次数: 2
EFFICIENCY AND SAFETY OF BILATERAL ULTRASOUND RECTUS SHEATH BLOCK IN URGENT LAPAROTOMY. 双侧超声直肌鞘阻滞在紧急剖腹手术中的有效性和安全性。
Pub Date : 2017-01-01 DOI: 10.18821/0201-7563-2017-62-1-60-63
I. A. Lovkov, D. Uvarov, E. Antipin, A. Ushakov, A. Karpunov, E. V. Nedashkovskiv
58 patients who underwent urgent laparotomy were included in this randomized controlled study. The efficacy and safety of bilateral ultrasound rectus sheath block of ropivacaine with systemic analgesia in comparison with only systemic analgesia were assessed. Rectus sheath block reduces the pain intensity and the consumption of opioids and declines the incidence of the adverse effects, therefore improving the quality of analgesia and postoperative comfort ofpatient.
58例接受紧急剖腹手术的患者被纳入这项随机对照研究。比较双侧超声直肌鞘阻滞罗哌卡因全身镇痛与单纯全身镇痛的疗效和安全性。直肌鞘阻滞降低了疼痛强度和阿片类药物的消耗,降低了不良反应的发生率,从而提高了患者的镇痛质量和术后舒适度。
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引用次数: 2
COMPARATIVE ASPECTS OF RESPIRATORY SUPPORT VIA LARINGEAL AIR DUCTS AND ENDOTRACHEAL TUBE FOR VIDEO-ASSISTED ONKOTHORACIC OPERATIONS. 经气管导管与气管内导管呼吸支持在胸腔镜手术中的比较。
Pub Date : 2017-01-01 DOI: 10.18821/0201-7563-2017-62-1-38-42
V. A. Zhikharev, Y. Malyshev, V. Porkhanov
GOAL To improve patient 's recovery after video-assisted thoracoscopic lobectomies (VATSL) by laryngeal mask using. METHODS This is a comparative analysis of 74 patients underwent VATSL. In 37 patients anaesthesia consisted of sevoflurane and fentanyl, myorelaxant, respiratory support via independent ventilation of either lung. In another 37patient 's anaesthesia protocol included respiratory support performed via laryngeal mask, propofol infusion and epidural analgesia with ropivacaine 0,2% and fentanyl. During the operation in both groups we evaluated hemodynamic, arterial blood gases, leukocytes, glucose and cortisol blood level, time to consciousness restoration (Aldrete-score) and time to discharge from ICU and duration of hospital stay, frequency of complications. RESULTS Patients with ventilation through laryngeal mask showed a statistically lower stress-reaction, avoided bronchoscopy with BAL and frequency of complications. Duration of inhospital stay in patients with laryngeal mask was 7±1,3 days; in intubated patients was 11±3,2 days. CONCLUSION In case of ventilation through the laryngeal mask hyper dynamic state of circulation, glycemia, leukocytes, cortisol blood level and arterial blood pH were lower, whereas Pa CO₂ increase. The number of bronchoscopy with BAL and time to discharge from ICU and from hospital not having risk of postoperative complications --lower.
目的提高电视胸腔镜肺叶切除术(VATSL)术后使用喉罩的患者的康复率。方法对74例VATSL患者进行对比分析。37例患者麻醉包括七氟醚和芬太尼,肌肉松弛剂,通过双肺独立通气的呼吸支持。另外37例患者的麻醉方案包括通过喉罩进行呼吸支持,异丙酚输注和硬膜外用罗哌卡因0.2%和芬太尼镇痛。在两组患者的手术过程中,我们评估了血流动力学、动脉血气、白细胞、血糖和皮质醇水平、意识恢复时间(aldrete评分)、出院时间和住院时间、并发症发生频率。结果经喉罩通气的患者应激反应较低,避免了BAL支气管镜检查,并发症发生率较低。戴喉罩患者住院时间为7±1.3 d;插管组为11±3.2 d。结论经喉罩通气后血液循环高动力状态下血糖、白细胞、皮质醇及动脉血pH值降低,Pa CO₂升高。有BAL的支气管镜检查次数和从ICU出院的时间以及没有术后并发症风险的医院-更低。
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引用次数: 0
EPIDURAL ANESTHESIA IN A PATIENT WITH LUNG APLASIA AND SKELETON DEFORMATION UNDERGOING ABDOMINAL HYSTERECTOMY: A CASE REPORT. 硬膜外麻醉在腹式子宫切除术中肺发育不全及骨骼变形患者的应用:1例报告。
Pub Date : 2017-01-01
A A Kasatkin, A R Nigmatullina, A A Vorozhtsova, E L Matveeva, I G Martyshko

Pulmonary agenesis combined with other malformations of the skeleton and internal organs in humans is a rare pathology. The choice of method of anesthesia before surgery in this patient may be some difficulties and limitations. We report the successful completion of surgery under epidural anesthesia. Ultrasound-guided epidural anesthesia allowed to take into account individual anatomicalfeatures ofthe patient and to avoid complications. This case demonstrates the ability to safely conduct epidural anesthesia in patients with malformations of the skeleton and internal organs.

肺发育不全合并其他骨骼和内部器官的畸形是一种罕见的病理。该患者术前麻醉方法的选择可能存在一定的困难和局限性。我们报告在硬膜外麻醉下成功完成手术。超声引导硬膜外麻醉可以考虑到患者的个体解剖特征,并避免并发症。本病例证明了在骨骼和内脏畸形患者中安全进行硬膜外麻醉的能力。
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引用次数: 0
POLYMORPHISM OF COLLECTION, TRANSFUSION AND EFFECTIVENESS OF DONOR PLATELETS CONCENTRATES. 供体浓缩血小板采集、输注及有效性的多态性。
Pub Date : 2017-01-01
M N Gubanova, R F Ayupova, E B Zhiburt

There were compared the results of 520 platelets transfusions in 8 centers. In the surveyed organizations part of prophylactic platelet transfusions ranged from 10% to 91%. On average platelet transfusions for the prevention of bleeding in 3,6 times more often than to stop the bleeding. 67,5% ofrecipients ofplatelets have oncology diseases. Target platelet concentrations for preventive transfusions seems high compared to modern evidence-based value - 10 @. 10⁰/l. 25% ofprophylactic transfusions included in the study were performed in patients with platelet count of 30 @. 10⁰l or more. In 76,7% of transfusions used platelet concentrates prepared by apheresis. Single whole blood- derived-units are used at 3,7 times more often than pooled platelets.

比较了8个中心520例血小板输注的结果。在被调查的组织中,预防性血小板输注的比例从10%到91%不等。平均输血小板用于预防出血的次数为止血的3、6倍。67.5%的血小板接受者患有肿瘤疾病。预防性输血的目标血小板浓度似乎高于现代循证值- 10 @。10⁰/ l。研究中25%的预防性输血是在血小板计数为30 @的患者中进行的。10⁰1或更多。在76.7%的输注中,使用了单采制备的血小板浓缩物。单个全血源性血小板的使用频率是合并血小板的3.7倍。
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引用次数: 0
[THE PREDICTIVE SIGNIFICANCE OF A MALLAMPATI SAMSOON & YOUNG SCORE AT OPERATIONS IN NOSE AND NASOPHARYNX AT CHILDREN]. [mallampati samsoon & young评分在儿童鼻咽手术中的预测意义]。
Pub Date : 2017-01-01 DOI: 10.18821/0201-7563-2017-62-1-6-9
E. Ivlev, E. V. Grigor’ev, V. Zhdanov, R. V. Zhdanov, A. Yulin
BACKGROUND The difficult airways at children happen rarely, but can lead to serious complications. MATERIALS AND METHODS Results of studying of sensitivity, specificity and predictive importance of a scale of Mallampati at 379 children aged from 3 till 17 years (ASA physical status I-II), who underwent surgery in the nasal cavity and nasopharynx, are presented in this article. Depending on result of Mallampati's score children have been distributed on 2 groups. In the first group 20 children had predictions of the difficult intubation of a trachea, 19 of them had the 3rd degree by Mallampati, 1 child had the 4th degree by Mallampati. In the second group 370 children had 1-2 class on Mallampati scale. During direct laryngoscopy, 8 patients had 3 degree on Cormack & Lehane and the 382 patients had 1-2 degree on Cormack & Lehane. The degree of the laryngoscopy's difficulty determine by results of the Mallampati Samsoon & Young. RESULTS AND CONCLUSION It is found out that sensitivity (Se) of a scale of Mallampati in modification of Samsoon & Young at children at operations in the nasal cavity and nasopharynx of 50%, specificity (Sp) of 96%, the positive predictive value (+VP) of 20%, the negative predictive value (-VP) of 99%.
儿童呼吸道困难很少发生,但可导致严重的并发症。材料与方法本文对379例接受鼻腔和鼻咽部手术的3 ~ 17岁(ASA身体状态I-II)儿童Mallampati量表的敏感性、特异性和预测重要性进行了研究。根据Mallampati的分数,孩子们被分为两组。在第一组20个孩子有气管插管困难的预测,其中19个是Mallampati的3度,1个是Mallampati的4度。第二组370名儿童按Mallampati量表分为1-2班。直接喉镜检查时,8例Cormack & Lehane为3度,382例Cormack & Lehane为1-2度。喉镜检查的困难程度由Mallampati Samsoon & Young的结果决定。结果与结论Samsoon & Young改良Mallampati量表在儿童鼻腔和鼻咽部手术中的敏感性(Se)为50%,特异性(Sp)为96%,阳性预测值(+VP)为20%,阴性预测值(-VP)为99%。
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引用次数: 0
PREECLAMPSIA AND IRON EXCHANGE. ARE THERE ANY COMMON PATTERNS? 子痫前期和铁交换。有什么共同模式吗?
Pub Date : 2016-11-01
Yu P Orlov, N V Govorova, V N Lukach, A V Mitrofnov, O D Dmitriva

The aim: Detarmination of correlation between the level ofserm iron and hemoglobin with clinical symptoms ofpreeclampsia.

Materials and methods: A prospective randomized controlled investigation of 62 women in the gestation of 30 to 39 weeks. Women were divided into 2 main groups. The first group included 38 nulliparous women with preeclampsia moderate degree (Io group) gestational age from 30 to 39 weeks, at the age of 26,8±2,7 years. The second main group included 24 nulliparous women with preeclampsia severe degree (II group) in gestational age from 30 to 39 weeks of similar age. The conditionfor inclusion in the main groups was iron supplementation in the period of total hemoglobin reducing < 115 g/l. The first control group (I) included 26 nulliparous women average 26,2±1,6 years, which admitted to a maternity hospital for planned Cesarean section. The second group (IQ included 22 healthy non-pregnant women at the age of 25,8±4,4 years. During hospitalization, before delivery and at 2 hours after delivery was investigated the concentration of total hemoglobin, serum iron, total bilirubin, creatinine, urea, endothelin-1 (immediately before delivery and after delivery). The total analyses of urine examined the number of red blood cells and white blood cells and protein concentration.

Results: It''s revealed that the serum iron level has a direct correlation with the level of blood preasure (r = 0,5412 and r = 0,6229) and concentration of endothelin- with total hemoglobin (r = 0,6446 in p < 0,03) and with serum iron concentration (r = 0,7841 in p < 0,02). Conclusuion. The analysis of conducted investigation allows to approve about the pathogenetic importance of iron in the development ofpreeclampsia and post-partum complications, that require new approaches of iron during gestation.

目的:探讨血清铁和血红蛋白水平与子痫前期临床症状的相关性。材料与方法:对62例妊娠30 ~ 39周的妇女进行前瞻性随机对照研究。女性被分为两组。第一组为38例中等程度先兆子痫的无产妇女(Io组),胎龄30 ~ 39周,年龄26.8±2.7岁。第二主要组为24例30 ~ 39周龄相近的无产先兆子痫严重程度妇女(II组)。主要组纳入条件为总血红蛋白降低< 115 g/l时补铁。第一对照组(I) 26例在妇产医院行计划剖宫产的未产妇女,平均年龄(26.2±1.6)岁。第二组(IQ)为22例健康未怀孕妇女,年龄25(8±4,4)岁。在住院期间、分娩前和分娩后2小时(分娩前和分娩后)测定总血红蛋白、血清铁、总胆红素、肌酐、尿素、内皮素-1的浓度。尿液的总分析检查了红细胞和白细胞的数量以及蛋白质浓度。结果:血清铁水平与血压水平(r = 0,5412和r = 0,6229)、内皮素-总血红蛋白浓度(r = 0,6446, p < 0,03)和血清铁浓度(r = 0,7841, p < 0,02)有直接关系。Conclusuion。通过对所进行的调查分析,可以肯定铁在子痫前期和产后并发症的发病中的重要作用,这需要在妊娠期间采用新的铁治疗方法。
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引用次数: 0
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Anesteziologiia i reanimatologiia
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