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[THE PREDICTIVE SIGNIFICANCE OF A MALLAMPATI SAMSOON & YOUNG SCORE AT OPERATIONS IN NOSE AND NASOPHARYNX AT CHILDREN]. [mallampati samsoon & young评分在儿童鼻咽手术中的预测意义]。
Pub Date : 2017-01-01
E V Ivlev, E V Grigor'ev, V V Zhdanov, R V Zhdanov, A A Yulin

Background: The difficult airways at children happen rarely, but can lead to serious complications.

Materials and methods: Results of studying of sensitivity, specificity and predictive importance of a scale of Mallampati at 379 children aged from 3 till 17 years (ASA physical status I-II), who underwent surgery in the nasal cavity and nasopharynx, are presented in this article. Depending on result of Mallampati's score children have been distributed on 2 groups. In the first group 20 children had predictions of the difficult intubation of a trachea, 19 of them had the 3rd degree by Mallampati, 1 child had the 4th degree by Mallampati. In the second group 370 children had 1-2 class on Mallampati scale. During direct laryngoscopy, 8 patients had 3 degree on Cormack & Lehane and the 382 patients had 1-2 degree on Cormack & Lehane. The degree of the laryngoscopy's difficulty determine by results of the Mallampati Samsoon & Young.

Results and conclusion: It is found out that sensitivity (Se) of a scale of Mallampati in modification of Samsoon & Young at children at operations in the nasal cavity and nasopharynx of 50%, specificity (Sp) of 96%, the positive predictive value (+VP) of 20%, the negative predictive value (-VP) of 99%.

背景:儿童气道困难很少发生,但可导致严重的并发症。材料与方法:本文报道了379例3 ~ 17岁(ASA身体状态I-II)接受鼻腔和鼻咽部手术的Mallampati量表的敏感性、特异性和预测重要性的研究结果。根据Mallampati的分数,孩子们被分为两组。在第一组20个孩子有气管插管困难的预测,其中19个是Mallampati的3度,1个是Mallampati的4度。第二组370名儿童按Mallampati量表分为1-2班。直接喉镜检查时,8例Cormack & Lehane为3度,382例Cormack & Lehane为1-2度。喉镜检查的困难程度由Mallampati Samsoon & Young的结果决定。结果与结论:Samsoon & Young改良Mallampati量表在儿童鼻腔和鼻咽部手术中的敏感性(Se)为50%,特异性(Sp)为96%,阳性预测值(+VP)为20%,阴性预测值(-VP)为99%。
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引用次数: 0
PREDICTION OF VARIOUS FORMS OF POSTOPERATIVE ACUTE LIVER FAILURE. 预测各种形式的术后急性肝衰竭。
Pub Date : 2017-01-01
S V Sin'kov, I V Zhilin, I B Zabolotskikh

165 patients over 18 years in the period from January 2014 to March 2015 were studied. The aim was to investigate the prognostic significance of known scale assessment of organ dysfunction in respect ofpostoperative hepatic failure. The development of acute liver failure was assessed on the basis of clinical and laboratory data, severity of the condition by scales MELD, Child-Turcotte-Pugh, Maddrey, Schindl, BILE score, SOFA. The paper identified the incidence offorms of acute liver failure (hepatic encephalopathy, hepatic coagulopathy, hepatorenal syndrome, systemic hemodynamic disorder mixed form) in patients after surgery on hepatobiliary system, and the dependence of the probability of their occurrence on the severity of the condition, calculated using a scales in the preoperative period. Calculated sensitivity and specificity in predicting scales investigatedforms of acute liver failure based on ROC-analysis. It was shown that the specialized rating scales have good predictive accuracy in respect of certain forms of hepatic insufficiency (Child-Tur-cotte-Pugh -for hemodynamic options and hepatic coagulopathy, MELD and SOFA scales -for hepatic encephalopathy SCHINDL -for hepatorenal syndrome and mixed forms of hepatic failure). None of the analyzed scales do not possess predictive value with respect to all forms of hepatic failure.

研究对象为2014年1月至2015年3月,年龄在18岁以上的165例患者。目的是探讨已知脏器功能障碍评分对术后肝功能衰竭的预后意义。根据临床和实验室数据、MELD量表、child - turcote - pugh量表、Maddrey量表、Schindl量表、胆汁胆汁评分、SOFA量表评估急性肝衰竭的发展情况。本文确定了手术后患者急性肝功能衰竭(肝性脑病、肝凝血功能障碍、肝肾综合征、全身血流动力学紊乱混合形式)在肝胆系统的发生率,以及术前使用a量表计算其发生概率与病情严重程度的依赖关系。基于roc分析的急性肝衰竭预测量表的计算敏感性和特异性。研究表明,对于某些形式的肝功能不全(child - turt -cotte- pugh -用于血流动力学选项和肝凝血病,MELD和SOFA量表-用于肝性脑病,SCHINDL -用于肝肾综合征和混合形式的肝功能衰竭),专业评分量表具有良好的预测准确性。所有分析的量表都对所有形式的肝衰竭具有预测价值。
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引用次数: 0
INTRA-OPERATIVE NEED FOR GLUCOSE IN NEWBORNS. 新生儿术中葡萄糖的需求。
Pub Date : 2017-01-01
Y U Kucherov, M M Nasser, Yu V Zhirkova

Introduction: One ofthe important goals of intraoperativefluid therapy in neonates is to ensure normal glycemic status. However there is no definitive guidance on the issue of intraoperative administration solutions containing glucose.

Materials and methods: a single-center study of intraoperative glycemic status in 60 newborns with congenital malformations was conducted. Age at the time of surgery amounted to Me 48 [24; 120] hours of life, the duration of surgery was 70 [60; 101] minutes. The children were divided into two groups: in group 1 (n = 30) intraoperative infusion therapy was only saline; in group 2 (n = 30) with salt solutions were simultaneously injected glucose in a dose of 2,3 mg/kg/ min. The glucose level in the blood was evaluated before operation, during operation every 30 minutes and at the end of surgical intervention, if it was necessary, was corrected.

Results: the study revealed high incidence of hypoglycemic conditions in children in group 1, especially during tracheal intubation and skin incision (40 episodes in 20 children). However the blood glucose level subsequently normalized and remained within the reference values. In group 2, the average glucose level in these stages was significantly greater than 4,4 [3,3; 5,2] mmol/l (p = 0,03), and did not go beyond normal values, remaining stable in all phases of the operation. There was a decrease in 2 times the frequency of episodes of hypoglycemia in group 2 (19 episodes in 12 patients). At the same time, more often fixed hyperglycemia in group 2.

Conclusions: intraoperative blood glucose in newborns is unstable indicator and requires a precise dosing of glucose in the infusion to avoid Hypo- and hyperglycemia.

新生儿术中液体治疗的重要目标之一是确保正常的血糖状态。然而,对于术中给药溶液中是否含有葡萄糖,尚无明确的指导意见。材料与方法:对60例先天性畸形新生儿术中血糖状况进行单中心研究。手术时年龄48岁[24;寿命120小时,手术时间70 [60];101分钟。将患儿分为两组:第一组(n = 30)术中仅输注生理盐水;2组(n = 30)同时用盐溶液注射葡萄糖,剂量分别为2、3 mg/kg/ min。术前、术中每30分钟测量一次血糖,手术结束时如有必要纠正血糖。结果:1组患儿低血糖发生率高,尤其是气管插管和皮肤切开时(20例患儿40次)。然而,血糖水平随后恢复正常,并保持在参考值之内。2组各阶段平均血糖水平均显著大于4,4 [3,3];[5,2] mmol/l (p = 0,03),且未超过正常值,在操作的各个阶段均保持稳定。2组患者低血糖发作次数减少2倍(12例患者19次)。同时,2组固定高血糖发生率更高。结论:新生儿术中血糖是一个不稳定的指标,需要在输注中精确给药以避免低血糖和高血糖。
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引用次数: 0
COMPARATIVE ASPECTS OF RESPIRATORY SUPPORT VIA LARINGEAL AIR DUCTS AND ENDOTRACHEAL TUBE FOR VIDEO-ASSISTED ONKOTHORACIC OPERATIONS. 经气管导管与气管内导管呼吸支持在胸腔镜手术中的比较。
Pub Date : 2017-01-01
V A Zhikharev, Yu P Malyshev, V A Porkhanov

Goal: To improve patient 's recovery after video-assisted thoracoscopic lobectomies (VATSL) by laryngeal mask using.

Methods: This is a comparative analysis of 74 patients underwent VATSL. In 37 patients anaesthesia consisted of sevoflurane and fentanyl, myorelaxant, respiratory support via independent ventilation of either lung. In another 37patient 's anaesthesia protocol included respiratory support performed via laryngeal mask, propofol infusion and epidural analgesia with ropivacaine 0,2% and fentanyl. During the operation in both groups we evaluated hemodynamic, arterial blood gases, leukocytes, glucose and cortisol blood level, time to consciousness restoration (Aldrete-score) and time to discharge from ICU and duration of hospital stay, frequency of complications.

Results: Patients with ventilation through laryngeal mask showed a statistically lower stress-reaction, avoided bronchoscopy with BAL and frequency of complications. Duration of inhospital stay in patients with laryngeal mask was 7±1,3 days; in intubated patients was 11±3,2 days.

Conclusion: In case of ventilation through the laryngeal mask hyper dynamic state of circulation, glycemia, leukocytes, cortisol blood level and arterial blood pH were lower, whereas Pa CO₂ increase. The number of bronchoscopy with BAL and time to discharge from ICU and from hospital not having risk of postoperative complications --lower.

目的:提高电视胸腔镜肺叶切除术(VATSL)术后使用喉罩的患者的康复率。方法:对74例VATSL患者进行对比分析。37例患者麻醉包括七氟醚和芬太尼,肌肉松弛剂,通过双肺独立通气的呼吸支持。另外37例患者的麻醉方案包括通过喉罩进行呼吸支持,异丙酚输注和硬膜外用罗哌卡因0.2%和芬太尼镇痛。在两组患者的手术过程中,我们评估了血流动力学、动脉血气、白细胞、血糖和皮质醇水平、意识恢复时间(aldrete评分)、出院时间和住院时间、并发症发生频率。结果:经喉罩通气的患者应激反应较低,避免了BAL支气管镜检查,并发症发生率较低。戴喉罩患者住院时间为7±1.3 d;插管组为11±3.2 d。结论:经喉罩通气后,血液循环高动力状态下血糖、白细胞、皮质醇、动脉血pH值降低,Pa CO₂升高。有BAL的支气管镜检查次数和从ICU出院的时间以及没有术后并发症风险的医院-更低。
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引用次数: 0
ELECTRICAL IMPEDANCE TOMOGRAPHY OF THE LUNGS IN THE PRACTICE OF THE ANESTHESIOLOGIST. 麻醉师在肺电阻抗断层扫描中的应用。
Pub Date : 2017-01-01
B A Aksel'rod, T A Pshenichnyy, I V Titova

The aim: To assess validity of EITL for mechanical ventilation optimization during GA.

Materials: 26 cardiac surgery patients participated in non-randomized comparative study. Everyone was ventilated with protective regimen: Vt - 6-8 ml/kg, breath rate - by normal EtCO2, i/e - 1.1,5. PEEP setting in group A (n = 15) was based on EITL data, in group B (n = 11, controls) - on the discretion of the anesthesiologist. We compared PEEP peak airway pressure (PAP), dynamic compliance, SpO2 and postoperative pulmonary complications. Bronchoscopy (FTBS) was performed after the onset of mechanical ventilation in 15 patients.

Results: Mask ventilation contributed redistribution of ventilation to ventral regions in 88,4% ofpatients. Ventilation by the end of surgery was remained un-changed more often in gr A than in gr B (86,6% vs. 36,6%, p = 0,026). PAP was higher in gr B by the end of surgery (19?1,4 vs. 17,3±2,2 cm H20; p = 0,03). Compliance by the end of surgery was not reduced below baseline's more frequently in gr A (73,3% in gr A vs. 27,2% in gr B, p = 0,053). After FTBS, ventilation after of mechanical ventilation renewal was comparable with baseline ' in 80%, deteriorated in 13,3% and improved in 6,6% ofpatients.

Conclusions: 1) EITL is a convenient toolfor ventilation dynamic evaluation during anesthesia; 2) EITL advances the mask ventilation, allows to set up appropriate PEEP during anesthesia and to evaluate safety of the disconnection during FTBS; 3) EITL contributes to professional education of anesthesiologists.

目的:评价EITL在遗传过程中机械通气优化中的有效性。材料:26例心脏手术患者参与非随机对照研究。所有患者均给予通气保护方案:Vt - 6- 8ml /kg,呼吸速率-正常EtCO2, i/e - 1.1,5。A组(n = 15)的PEEP设置基于EITL数据,B组(n = 11,对照组)的PEEP设置由麻醉师决定。我们比较了PEEP气道峰值压(PAP)、动态顺应性、SpO2和术后肺部并发症。15例患者在机械通气后行支气管镜检查(FTBS)。结果:88.4%的患者通过面罩通气将通气重新分配到腹侧。手术结束时,A组的通气保持不变的频率高于B组(86.6%比36.6%,p = 0.026)。手术结束时,B组PAP增高(19?1,4 vs. 17,3±2,2 cm H20;P = 0,03)。手术结束时依从性在A组没有更频繁地低于基线(A组为73.3%,B组为27.2%,p = 0.053)。在FTBS后,80%的患者机械通气更新后的通气与基线相当,13.3%的患者恶化,6.6%的患者改善。结论:1)EITL是一种方便的麻醉通气动态评估工具;2) EITL推进了面罩通气,允许在麻醉期间设置适当的PEEP,并评估FTBS期间断开连接的安全性;3) EITL有助于麻醉医师的专业教育。
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引用次数: 0
POLYMORPHISM OF COLLECTION, TRANSFUSION AND EFFECTIVENESS OF DONOR PLATELETS CONCENTRATES. 供体浓缩血小板采集、输注及有效性的多态性。
Pub Date : 2017-01-01 DOI: 10.18821/0201-7563-2017-62-1-77-79
M. Gubanova, R. Ayupova, E. Zhiburt
There were compared the results of 520 platelets transfusions in 8 centers. In the surveyed organizations part of prophylactic platelet transfusions ranged from 10% to 91%. On average platelet transfusions for the prevention of bleeding in 3,6 times more often than to stop the bleeding. 67,5% ofrecipients ofplatelets have oncology diseases. Target platelet concentrations for preventive transfusions seems high compared to modern evidence-based value - 10 @. 10⁰/l. 25% ofprophylactic transfusions included in the study were performed in patients with platelet count of 30 @. 10⁰l or more. In 76,7% of transfusions used platelet concentrates prepared by apheresis. Single whole blood- derived-units are used at 3,7 times more often than pooled platelets.
比较了8个中心520例血小板输注的结果。在被调查的组织中,预防性血小板输注的比例从10%到91%不等。平均输血小板用于预防出血的次数为止血的3、6倍。67.5%的血小板接受者患有肿瘤疾病。预防性输血的目标血小板浓度似乎高于现代循证值- 10 @。10⁰/ l。研究中25%的预防性输血是在血小板计数为30 @的患者中进行的。10⁰1或更多。在76.7%的输注中,使用了单采制备的血小板浓缩物。单个全血源性血小板的使用频率是合并血小板的3.7倍。
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引用次数: 2
ELECTRICAL IMPEDANCE TOMOGRAPHY OF THE LUNGS IN THE PRACTICE OF THE ANESTHESIOLOGIST. 麻醉师在肺电阻抗断层扫描中的应用。
Pub Date : 2017-01-01 DOI: 10.18821/0201-7563-2017-62-1-43-46
B. A. Aksel'rod, T. Pshenichnyy, I. Titova
THE AIM To assess validity of EITL for mechanical ventilation optimization during GA. MATERIALS 26 cardiac surgery patients participated in non-randomized comparative study. Everyone was ventilated with protective regimen: Vt - 6-8 ml/kg, breath rate - by normal EtCO2, i/e - 1.1,5. PEEP setting in group A (n = 15) was based on EITL data, in group B (n = 11, controls) - on the discretion of the anesthesiologist. We compared PEEP peak airway pressure (PAP), dynamic compliance, SpO2 and postoperative pulmonary complications. Bronchoscopy (FTBS) was performed after the onset of mechanical ventilation in 15 patients. RESULTS Mask ventilation contributed redistribution of ventilation to ventral regions in 88,4% ofpatients. Ventilation by the end of surgery was remained un-changed more often in gr A than in gr B (86,6% vs. 36,6%, p = 0,026). PAP was higher in gr B by the end of surgery (19?1,4 vs. 17,3±2,2 cm H20; p = 0,03). Compliance by the end of surgery was not reduced below baseline's more frequently in gr A (73,3% in gr A vs. 27,2% in gr B, p = 0,053). After FTBS, ventilation after of mechanical ventilation renewal was comparable with baseline ' in 80%, deteriorated in 13,3% and improved in 6,6% ofpatients. CONCLUSIONS 1) EITL is a convenient toolfor ventilation dynamic evaluation during anesthesia; 2) EITL advances the mask ventilation, allows to set up appropriate PEEP during anesthesia and to evaluate safety of the disconnection during FTBS; 3) EITL contributes to professional education of anesthesiologists.
目的评价EITL在遗传过程中机械通气优化中的有效性。材料26例心脏手术患者参与非随机对照研究。所有患者均给予通气保护方案:Vt - 6- 8ml /kg,呼吸速率-正常EtCO2, i/e - 1.1,5。A组(n = 15)的PEEP设置基于EITL数据,B组(n = 11,对照组)的PEEP设置由麻醉师决定。我们比较了PEEP气道峰值压(PAP)、动态顺应性、SpO2和术后肺部并发症。15例患者在机械通气后行支气管镜检查(FTBS)。结果88.4%的患者使用smask通气有助于将通气重新分配到腹侧。手术结束时,A组的通气保持不变的频率高于B组(86.6%比36.6%,p = 0.026)。手术结束时,B组PAP增高(19?1,4 vs. 17,3±2,2 cm H20;P = 0,03)。手术结束时依从性在A组没有更频繁地低于基线(A组为73.3%,B组为27.2%,p = 0.053)。在FTBS术后,80%的患者机械通气更新后的通气与基线相当,13.3%的患者通气恶化,6.6%的患者通气改善。结论1)EITL是一种方便的麻醉期间通气动态评估工具;2) EITL推进了面罩通气,允许在麻醉期间设置适当的PEEP,并评估FTBS期间断开连接的安全性;3) EITL有助于麻醉医师的专业教育。
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引用次数: 0
COMPARISON OF EMERGENCE AND RECOVERY CHARACTERISTICS OF SEVOFLURANE AND DESFLURANE IN PEDIATRIC AMBULATORY SURGERY. 七氟醚和地氟醚在儿科门诊手术中的出现和恢复特点比较。
Pub Date : 2017-01-01
A V Lsakov, O N Paponov, E G Aaavelvan, S M Stenanenko

Background: A big number ofshort-time surgery performed in one-day pediatric department requires the permanent search of an ideal anesthetic for the maximum quickly children ' take home with the minimum ofpostoperation complications.

The aim: to compare the emergence and recovery characteristics ofsevoflurane and desflurane maintenance ofanesthe- sia in children undergoing ambulatory surgery.

Results and conclusion: There were no significant differences among the two groups in hemodynamic parameters, the incidence of postoperative vomiting and cough. But desflurane maintenance of anesthesia resulted in the fastest early emergence from anesthesia, the lack of incidence ofpostoperative agitation compared with sevoflurane.

背景:在儿科进行的大量短期手术中,需要长期寻找一种理想的麻醉剂,以最大限度地快速将儿童带回家,并减少术后并发症。目的:比较七氟醚和地氟醚维持麻醉对门诊手术患儿的出现和恢复特点。结果与结论:两组患者在血流动力学参数、术后呕吐、咳嗽发生率方面无显著差异。但与七氟醚相比,地氟醚维持麻醉的早期苏醒最快,术后躁动发生率低。
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引用次数: 0
ANESTHETIC MANAGEMENT OF DELIVERY IN PATIENTS WITH COMPLEMENT-ASSOCIATED DISORDERS. CLINICAL OBSERVATION OF A PREGNANT WOMAN WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA. 补体相关疾病患者分娩的麻醉管理。孕妇阵发性夜间血红蛋白尿1例临床观察。
Pub Date : 2017-01-01
E Yu Uptyamova, A A Golovin, E M Shifman

There was a case in MRRIOG (Moscow Regional Research Institute of Obstetrics and Gynecology) in 2015 when pregnant patient with paroxysmal nocturnal hemoglobinuria(PNH) has successfully passed through a delivery process. This paper analyzes the medical history, clinical, laboratory and instrumental examination, particularly anesthesia tactics for the patients with complement-associated diseases during delivery. The presented clinical case demonstrates the need for and the importance of early diagnosis of PNH in pregnant women. Of course, women with PNH are one of the most complex contingent ofpregnant women, threatened by the development of obstetric and anesthetic complications, and it requires constant monitoring of clinical and laboratory parameters of their condition, the joint hematologist, obstetri- cian and anesthesiologist observationand delivery in hospitals of III and IV levels.

2015年莫斯科地区妇产科研究所(MRRIOG)有一例阵发性夜间血红蛋白尿(PNH)孕妇顺利通过分娩过程。本文分析了补体相关疾病患者的病史、临床、实验室和器械检查,特别是分娩时的麻醉策略。所提出的临床病例表明需要和重要性的早期诊断PNH在孕妇。当然,患有PNH的妇女是最复杂的孕妇之一,受到产科和麻醉并发症的威胁,需要持续监测其病情的临床和实验室参数,并在三级和四级医院由血液科医生、产科医生和麻醉科医生联合观察和分娩。
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引用次数: 0
EVACUATION OF PATIENTS WITH RESPIRATORY FAILURE ON EXTRACORPOREAL MEMBRANE OXYGENATION. 体外膜氧合对呼吸衰竭患者的疏散作用。
Pub Date : 2017-01-01 DOI: 10.18821/0201-7563-2017-62-1-32-35
A. Shchegolev, D. Shelukhin, E. N. Ershov, A. I. Pavlov, A. A. Golomidov
Realising for thefirst time in Russia the transportation of a patient with critical respiratory failure in conditions of EC-MO-therapy, the authors have accumulated great experience of its application at the stage of inter-hospital evacuation. This category ofpatients previously considered non-transportable by the severity of their condition. Having conducted a retrospective analysis of clinical experience in the use of high-tech medical care method, the authors received a zero mortality and questioned the possible new criteria and recommendations in assessing risk of death in patients with life-threatening conditions at the stage of inter-hospital transportation.
在俄罗斯首次实现了在ec - mo治疗条件下的重症呼吸衰竭患者的运输,作者积累了其在医院间后送阶段应用的丰富经验。这类患者以前因其病情的严重程度被认为是不可转移的。在对使用高科技医疗方法的临床经验进行回顾性分析后,作者获得了零死亡率,并对在医院间转运阶段评估危及生命的病人死亡风险的可能的新标准和建议提出了质疑。
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引用次数: 3
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