{"title":"The carbohydrate antigenic determinant 19-9 (CA 19-9): a monoclonal antibody defined tumor marker.","authors":"B C DelVillano, V R Zurawski","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79229,"journal":{"name":"Laboratory and research methods in biology and medicine","volume":"8 ","pages":"269-82"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17260308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Arteriography of hepatic masses.","authors":"R Pereiras","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79229,"journal":{"name":"Laboratory and research methods in biology and medicine","volume":"7 ","pages":"369-89"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17373203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the more than 80 years that it has been practiced, laparoscopy has proved to be a procedure that provides a high level of differential diagnostic information. Although its main indications, general application, and practical assessment have been variously assessed by various investigators at different times in different countries, our own experience, based on more than 12,500 investigations involving predominantly hepatological problems, indicates that laparoscopy today remains one of the main pillars of our differential-diagnostic armamentarium.
{"title":"Diagnostic procedures in the evaluation of hepatic diseases. Laparoscopy.","authors":"H Henning","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the more than 80 years that it has been practiced, laparoscopy has proved to be a procedure that provides a high level of differential diagnostic information. Although its main indications, general application, and practical assessment have been variously assessed by various investigators at different times in different countries, our own experience, based on more than 12,500 investigations involving predominantly hepatological problems, indicates that laparoscopy today remains one of the main pillars of our differential-diagnostic armamentarium.</p>","PeriodicalId":79229,"journal":{"name":"Laboratory and research methods in biology and medicine","volume":"7 ","pages":"469-88, C2-8"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17373204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic procedures in the evaluation of hepatic diseases. Functional evaluation. Other investigative indices: endotoxin.","authors":"D S Camara, J P Nolan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79229,"journal":{"name":"Laboratory and research methods in biology and medicine","volume":"7 ","pages":"195-8"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17413508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic procedures in the evaluation of hepatic diseases. Clinical evaluation.","authors":"K R Falchuk","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79229,"journal":{"name":"Laboratory and research methods in biology and medicine","volume":"7 ","pages":"3-13"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17413512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Testing for autoantibodies has an important place in the clinical immunodiagnostic laboratory. The presence of autoantibodies can aid in the diagnosis or confirmation of AID, as in the case of chronic thyroiditis, which is invariably associated with thyroid antibodies. Conversely the lack of antibody can help exclude the diagnosis of disease. The diagnosis of SLE can virtually be ruled out in patients who do not have ANA. Finding autoantibodies may help in difficult differential diagnosis, such as in those patients with liver disorders. Sometimes the type of autoantibody may be an indicator of prognosis. An example is in those SLE patients who develop anti-DNA antibodies, as mentioned previously. Along the same line, monitoring ANA has been of value in establishing effective treatment in SLE patients, as ANA disappear upon therapy and recur with return of active disease. The detection of autoantibodies may also be used for the identification of other family members of patients with AID who may have a greater risk of developing the disease. Finally, autoantibody detection has provided a tool for basic research which has aided both in classification of disease and increased our understanding of the normal control of immune regulation.
{"title":"Profile of autoantibodies in human diseases.","authors":"C L Burek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Testing for autoantibodies has an important place in the clinical immunodiagnostic laboratory. The presence of autoantibodies can aid in the diagnosis or confirmation of AID, as in the case of chronic thyroiditis, which is invariably associated with thyroid antibodies. Conversely the lack of antibody can help exclude the diagnosis of disease. The diagnosis of SLE can virtually be ruled out in patients who do not have ANA. Finding autoantibodies may help in difficult differential diagnosis, such as in those patients with liver disorders. Sometimes the type of autoantibody may be an indicator of prognosis. An example is in those SLE patients who develop anti-DNA antibodies, as mentioned previously. Along the same line, monitoring ANA has been of value in establishing effective treatment in SLE patients, as ANA disappear upon therapy and recur with return of active disease. The detection of autoantibodies may also be used for the identification of other family members of patients with AID who may have a greater risk of developing the disease. Finally, autoantibody detection has provided a tool for basic research which has aided both in classification of disease and increased our understanding of the normal control of immune regulation.</p>","PeriodicalId":79229,"journal":{"name":"Laboratory and research methods in biology and medicine","volume":"8 ","pages":"101-20"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17419671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunologic detection of bacterial antigens.","authors":"R C Tilton","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79229,"journal":{"name":"Laboratory and research methods in biology and medicine","volume":"8 ","pages":"183-90"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17419673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunological characteristics of human lymphomas.","authors":"J W Parker","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79229,"journal":{"name":"Laboratory and research methods in biology and medicine","volume":"8 ","pages":"121-46"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17701063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Liver biopsy: special histologic techniques including immunopathology.","authors":"G Chejfec","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79229,"journal":{"name":"Laboratory and research methods in biology and medicine","volume":"7 ","pages":"509-14, C13-6"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17259065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liver disease is associated with abnormalities in plasma lipids and lipoprotein structure and metabolism. These abnormalities are not specific for the type of liver disease. The severity of the changes does, however, parallel the severity of the liver disease. Lipoprotein abnormalities may also have prognostic significance; but there is no good correlation between the abnormalities in plasma lipoproteins and more standard liver-function tests. Due to the marked derangements that occur in lipoproteins, liver disease provides a useful model to study lipoprotein metabolism.
{"title":"Lipoprotein metabolism in liver disease.","authors":"P H Green","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Liver disease is associated with abnormalities in plasma lipids and lipoprotein structure and metabolism. These abnormalities are not specific for the type of liver disease. The severity of the changes does, however, parallel the severity of the liver disease. Lipoprotein abnormalities may also have prognostic significance; but there is no good correlation between the abnormalities in plasma lipoproteins and more standard liver-function tests. Due to the marked derangements that occur in lipoproteins, liver disease provides a useful model to study lipoprotein metabolism.</p>","PeriodicalId":79229,"journal":{"name":"Laboratory and research methods in biology and medicine","volume":"7 ","pages":"199-204"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17413509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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