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Comparison of the recovery from isoflurane anesthesia with or without fentanyl infusion in patients undergoing elective supratentorial craniotomy. 选择性幕上开颅术患者在异氟醚麻醉下输注芬太尼或不输注芬太尼恢复的比较。
Pub Date : 2003-12-01
Hsin-Jung Tsai, Kuei-Feng Tsou, Hsu-Tang Liu, Chi-Chun Chu, Cheng-Ming Tsao, Mei-Yung Tsou, Shen-Kou Tsai

Background: Several anesthetic agents have been used successfully to provide optimal anesthetic maintenance in neurosurgery for supratentorial tumors. Due to longer surgical time that these procedures demand and thoughout avoidance of intracranial bleeding from a hastened emergence of anesthesia in the operating room, the neurosurgeons in our hospital favor a placid late emergence from anesthesia in the neurosurgical intensive care unit (NCU). Accordingly, we designed this clinical trial to compare the effects of volatile general anesthesia with or without fentanyl infusion on postoperative hemodynamics, Glasgow coma scale (GCS) score, extubation time, as well as neurological outcome in patients after craniotomy.

Methods: Forty-two patients undergoing elective surgery for supratentorial lesions were randomly divided into two anesthetic groups. In isoflurane group, after induction, anesthesia was maintained with isoflurane up to 1.2% end-tidal concentration. In fentanyl-isoflurane group, an infusion of fentanyl was started at a rate of 3 micrograms/kg/h after induction, and anesthesia was maintained with isoflurane up to 0.6% end-tidal concentration. All the anesthetics were discontinued once the surgical wound was dressed. We studied the postoperative hemodynamics and several recovery variables for 48 h after completion of anesthesia.

Results: The time from completion of surgery to extubation was shorter in isoflurane group (9.3 +/- 6.6 h) as compared with fentanyl-isoflurane group (14 +/- 3.5 h, P < 0.05). Better GCS score was seen in isoflurane group in the early recovery period. However, both groups did not differ in both average postoperative blood pressure and heart rate and there was no significant difference between 2 groups in total duration of the postoperative NCU stay.

Conclusions: In pursuance of the policy of late emergence, we are of the opinion that isoflurane anesthesia offers an earlier recovery than fentanyl-isoflurane anesthesia in patients undergoing supratentorial craniotomy.

背景:在幕上肿瘤的神经外科手术中,已经成功地使用了几种麻醉剂来提供最佳的麻醉维持。由于这些手术需要较长的手术时间,并且在手术室中避免因麻醉加速出现颅内出血,因此我们医院的神经外科医生倾向于在神经外科重症监护病房(NCU)中平静地结束麻醉。因此,我们设计了本临床试验,比较挥发性全麻输注芬太尼或不输注芬太尼对开颅术后患者血流动力学、格拉斯哥昏迷评分(GCS)、拔管时间以及神经系统预后的影响。方法:42例幕上病变择期手术患者随机分为两组。异氟醚组诱导后,以异氟醚维持麻醉至1.2%潮末浓度。芬太尼-异氟醚组诱导后以3微克/千克/小时的速率开始芬太尼输注,异氟醚维持麻醉至0.6%潮末浓度。手术伤口包扎完毕后,所有麻醉药均停止使用。我们研究了麻醉结束后48小时的术后血流动力学和几个恢复变量。结果:异氟醚组手术完成至拔管时间(9.3 +/- 6.6 h)短于芬太尼-异氟醚组(14 +/- 3.5 h, P < 0.05)。异氟醚组恢复期早期GCS评分较高。然而,两组术后平均血压和心率均无差异,两组术后NCU总住院时间无显著差异。结论:在晚出现的原则下,我们认为异氟醚麻醉比芬太尼-异氟醚麻醉对幕上开颅患者的恢复更早。
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引用次数: 0
Comparison of the recovery from isoflurane anesthesia with or without fentanyl infusion in patients undergoing elective supratentorial craniotomy. 选择性幕上开颅术患者在异氟醚麻醉下输注芬太尼或不输注芬太尼恢复的比较。
Pub Date : 2003-12-01 DOI: 10.6955/AAS.200312.0179
H. Tsai, Kuei-Feng Tsou, Hsu-Tang Liu, C. Chu, C. Tsao, M. Tsou, S. Tsai
BACKGROUNDSeveral anesthetic agents have been used successfully to provide optimal anesthetic maintenance in neurosurgery for supratentorial tumors. Due to longer surgical time that these procedures demand and thoughout avoidance of intracranial bleeding from a hastened emergence of anesthesia in the operating room, the neurosurgeons in our hospital favor a placid late emergence from anesthesia in the neurosurgical intensive care unit (NCU). Accordingly, we designed this clinical trial to compare the effects of volatile general anesthesia with or without fentanyl infusion on postoperative hemodynamics, Glasgow coma scale (GCS) score, extubation time, as well as neurological outcome in patients after craniotomy.METHODSForty-two patients undergoing elective surgery for supratentorial lesions were randomly divided into two anesthetic groups. In isoflurane group, after induction, anesthesia was maintained with isoflurane up to 1.2% end-tidal concentration. In fentanyl-isoflurane group, an infusion of fentanyl was started at a rate of 3 micrograms/kg/h after induction, and anesthesia was maintained with isoflurane up to 0.6% end-tidal concentration. All the anesthetics were discontinued once the surgical wound was dressed. We studied the postoperative hemodynamics and several recovery variables for 48 h after completion of anesthesia.RESULTSThe time from completion of surgery to extubation was shorter in isoflurane group (9.3 +/- 6.6 h) as compared with fentanyl-isoflurane group (14 +/- 3.5 h, P < 0.05). Better GCS score was seen in isoflurane group in the early recovery period. However, both groups did not differ in both average postoperative blood pressure and heart rate and there was no significant difference between 2 groups in total duration of the postoperative NCU stay.CONCLUSIONSIn pursuance of the policy of late emergence, we are of the opinion that isoflurane anesthesia offers an earlier recovery than fentanyl-isoflurane anesthesia in patients undergoing supratentorial craniotomy.
背景:在幕上肿瘤的神经外科手术中,已经成功地使用了几种麻醉剂来提供最佳的麻醉维持。由于这些手术需要较长的手术时间,并且在手术室中避免因麻醉加速出现颅内出血,因此我们医院的神经外科医生倾向于在神经外科重症监护病房(NCU)中平静地结束麻醉。因此,我们设计了本临床试验,比较挥发性全麻输注芬太尼或不输注芬太尼对开颅术后患者血流动力学、格拉斯哥昏迷评分(GCS)、拔管时间以及神经系统预后的影响。方法42例幕上病变择期手术患者随机分为两组。异氟醚组诱导后,以异氟醚维持麻醉至1.2%潮末浓度。芬太尼-异氟醚组诱导后以3微克/千克/小时的速率开始芬太尼输注,异氟醚维持麻醉至0.6%潮末浓度。手术伤口包扎完毕后,所有麻醉药均停止使用。我们研究了麻醉结束后48小时的术后血流动力学和几个恢复变量。结果异氟醚组手术结束至拔管时间(9.3 +/- 6.6 h)短于芬太尼-异氟醚组(14 +/- 3.5 h, P < 0.05)。异氟醚组恢复期早期GCS评分较高。然而,两组术后平均血压和心率均无差异,两组术后NCU总住院时间无显著差异。结论在晚出现的原则下,异氟醚麻醉比芬太尼-异氟醚麻醉对幕上开颅术患者的恢复更早。
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引用次数: 2
Anesthetic management of intracranial hemorrhage from huge arteriovenous malformations in late pregnancy--a case report. 妊娠晚期巨大动静脉畸形颅内出血的麻醉处理1例。
Pub Date : 2003-12-01 DOI: 10.6955/AAS.200312.0209
H. Lao, S. Hseu, Yu-Yin Huang, Ya-Sheng Yu, S. Tsai
Intracranial hemorrhage (ICH) from an arteriovenous malformation (AVM) in pregnancy is quite rare and could lead to exceedingly high maternal and fetal morbidity and mortality. We report a 26-year-old woman at 36 weeks' gestation who sustained ICH due to two huge AVMs. For preventing from progressive increased intracranial pressure (IICP), Cesarean section under general anesthesia was performed successfully. Herein, we also discuss the anesthetic management after reviewing the related current literatures.
颅内出血(ICH)由动静脉畸形(AVM)在妊娠是相当罕见的,可导致极高的产妇和胎儿的发病率和死亡率。我们报告一位妊娠36周的26岁妇女,由于两个巨大的静脉畸形而持续ICH。为防止进行性颅内压增高(IICP),全麻下成功行剖宫产术。在此,我们也在回顾相关文献的基础上讨论麻醉管理。
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引用次数: 3
Unexpected intraoperative hypercapnia due to undetected expiratory valve dysfunction--a case report. 术中意外高碳酸血症因未发现的呼气瓣膜功能障碍- 1例报告。
Pub Date : 2003-12-01
Sin-Ru Han, Chee-Sang Ho, Chen-Hui Jin, Chien-Chiang Liu

The normally functioning of anesthetic circle system depends mainly on the integrity of both inspiratory and expiratory unidirectional valves which keep the inspiratory gas will not be contaminated by the expired CO2. In case there is a leakage defect in one or both of these valves, i.e. inability to keep tightly closed during the cycle, retrograde gas flow may happen and the exhaled CO2 may get into the inspiratory limb, resulting in rebreathing and hypercapnia with disastrous aftermath. Here we report a rather rare incident of unrecognized expiratory valve insufficiency that was not detected before anesthesia in a 40-year-old female patient who developed intraoperative hypercapnea during general anesthesia with mechanical ventilation. Discussions on the causes, management, and prevention of hypercapnia due to respiratory valve dysfunction are presented.

麻醉循环系统的正常工作主要依赖于吸气和呼气单向阀的完整性,以保证吸入气体不被过期的CO2污染。如果其中一个或两个阀门出现泄漏缺陷,即在循环过程中不能保持紧密关闭,则可能发生气体倒流,呼出的CO2进入吸气肢,导致再呼吸和高碳酸血症,后果严重。在此,我们报告一例40岁女性患者,在机械通气全麻下发生术中呼吸急促,在麻醉前未发现的未被识别的呼气瓣膜功能不全。讨论了呼吸瓣膜功能障碍引起的高碳酸血症的原因、处理和预防。
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引用次数: 0
Unexpected intraoperative hypercapnia due to undetected expiratory valve dysfunction--a case report. 术中意外高碳酸血症因未发现的呼气瓣膜功能障碍- 1例报告。
Pub Date : 2003-12-01 DOI: 10.6955/AAS.200312.0215
Sin-Ru Han, C. Ho, Chen-Hui Jin, Chien-Chiang Liu
The normally functioning of anesthetic circle system depends mainly on the integrity of both inspiratory and expiratory unidirectional valves which keep the inspiratory gas will not be contaminated by the expired CO2. In case there is a leakage defect in one or both of these valves, i.e. inability to keep tightly closed during the cycle, retrograde gas flow may happen and the exhaled CO2 may get into the inspiratory limb, resulting in rebreathing and hypercapnia with disastrous aftermath. Here we report a rather rare incident of unrecognized expiratory valve insufficiency that was not detected before anesthesia in a 40-year-old female patient who developed intraoperative hypercapnea during general anesthesia with mechanical ventilation. Discussions on the causes, management, and prevention of hypercapnia due to respiratory valve dysfunction are presented.
麻醉循环系统的正常工作主要依赖于吸气和呼气单向阀的完整性,以保证吸入气体不被过期的CO2污染。如果其中一个或两个阀门出现泄漏缺陷,即在循环过程中不能保持紧密关闭,则可能发生气体倒流,呼出的CO2进入吸气肢,导致再呼吸和高碳酸血症,后果严重。在此,我们报告一例40岁女性患者,在机械通气全麻下发生术中呼吸急促,在麻醉前未发现的未被识别的呼气瓣膜功能不全。讨论了呼吸瓣膜功能障碍引起的高碳酸血症的原因、处理和预防。
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引用次数: 3
Implications of intrathecal pertussis toxin animal model on the cellular mechanisms of neuropathic pain syndrome. 鞘内百日咳毒素动物模型对神经性疼痛综合征细胞机制的影响。
Pub Date : 2003-12-01 DOI: 10.6955/AAS.200312.0187
Z. Wen, Yi‐Chen Chang, Chih-Shung Wong
Like opioid tolerance, neuropathic pain syndrome manifested by hyperalgesia and allodynia responds poorly to opioids. Hitherto, its development is still not clear and its treatment and prevention are still disputable. Pertussis toxin (PTX) which ADP-ribosylates the alpha-subunit of inhibitory guanine nucleotide binding regulatory proteins (Gi/Go), is used to induce morphine tolerance through intrathecal (i.t.) injection. It decreases the antinociceptive effect of opioid receptor agonists, and produces a thermal hyperalgesia as well. With treatment of PTX the inhibitory Gi- and Go-proteins signal transduction is inactivated. Inhibition of the inhibitory system would likely lead to a predominance of the excitatory system. Intrathecal PTX administration has also been suggested as a model for study of the central mechanisms of neuropathic pain. In our previous studies, with intrathecal microdialysis and drug delivery techniques, we correlated the biochemical and pharmacological effects on the behavioral expressions of i.t. PTX-treated rats. Intrathecal PTX administration would induce thermal hyperalgesia in rats, with accompaniments of a prolonged increase in the concentrations of excitatory amino acids (EAAs), glutamate and aspartate, and a decrease in the concentration of the inhibitory amino acid (IAA) glycine in the spinal CSF dialysates. The PTX-induced thermal hyperalgesia peaked between day 2 and 4, but no cold allodynia is observed; i.t. administration of N-methyl-D-aspartate (NMDA) receptor antagonist, D-2-amino-5-phosponovaleric acid (D-AP5), glycine and protein kinase C (PKC) inhibitor chelerythrine attenuated the thermal hyperalgesia. The PKC gamma content of both synaptosomal and cytosolic fractions were significantly increased in PTX-treated rats. In contrast, the levels of PKC alpha, beta I, or beta II isozymes in these fractions were unaffected. Infusion of NMDA antagonist D-AP5 prevented both the thermal hyperalgesia and the increase in PKC gamma expression in PTX-treated rats. Similar to our previous report, i.t. PTX reduced morphine's analgesic effect. PKC inhibitor chelerythrine attenuated this reduction of morphine's analgesia, and an inhibition of the morphine-evoked EAAs release was observed in PTX-treated rats as well. Taken together, i.t. PTX-induced neuropathic pain syndrome is accompanied by increasing of EAAs, decreasing of IAA release, and a selective increasing of PKC gamma expression in the spinal cord. Inhibition of PKC not only blocked thermal hyperalgesia, but also reversed the reduction of morphine's analgesic effect in PTX-rats. These results suggest that PTX-induced neuropathic pain syndromes are involved in EAAs, IAAs and PKC alternations.
与阿片类药物耐受性一样,以痛觉过敏和异常性疼痛为表现的神经性疼痛综合征对阿片类药物的反应较差。迄今为止,其发展尚不清楚,其治疗和预防仍存在争议。百日咳毒素(PTX)是抑制鸟嘌呤核苷酸结合调节蛋白(Gi/Go)的α亚基腺苷化核糖,通过鞘内注射诱导吗啡耐受。它降低了阿片受体激动剂的抗痛觉作用,并产生热痛觉过敏。在PTX治疗下,抑制Gi-和go -蛋白信号转导被灭活。抑制系统的抑制可能导致兴奋系统的优势。鞘内给药PTX也被认为是神经性疼痛中枢机制研究的一个模型。在我们之前的研究中,我们通过鞘内微透析和给药技术,将生化和药理作用与itptx治疗大鼠的行为表达联系起来。鞘内PTX政府将诱导大鼠热痛觉过敏,伴兴奋性氨基酸(EAAs)、谷氨酸和天冬氨酸浓度的延长升高,以及脊髓脊液中抑制性氨基酸(IAA)甘氨酸浓度的降低。ptx诱导的热痛觉过敏在第2天至第4天达到高峰,但未观察到冷异常性痛;给予n -甲基- d -天冬氨酸(NMDA)受体拮抗剂、d -2-氨基-5-磷戊酸(D-AP5)、甘氨酸和蛋白激酶C (PKC)抑制剂chelerythrine可减轻热痛觉过敏。ptx处理大鼠突触体和细胞质部分PKC γ含量均显著升高。相比之下,这些部分中PKC α, β I或β II同工酶的水平不受影响。输注NMDA拮抗剂D-AP5可阻止ptx处理大鼠的热痛觉过敏和PKC γ表达的增加。与我们之前的报道相似,i.t PTX降低了吗啡的镇痛作用。PKC抑制剂chelerythrine减弱了吗啡镇痛的减少,并且在ptx治疗的大鼠中也观察到吗啡诱发的EAAs释放的抑制。综上所述,ptx诱导的神经性疼痛综合征伴EAAs升高,IAA释放减少,脊髓PKC γ表达选择性升高。PKC的抑制不仅阻断了ptx大鼠的热痛觉过敏,而且逆转了吗啡镇痛作用的减弱。这些结果表明,ptx诱导的神经性疼痛综合征与EAAs、IAAs和PKC的改变有关。
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引用次数: 10
A two-center survey of cardiac events and peri-operative managements of cardiac patients undergoing non-cardiac surgery in Taiwanese population. 台湾非心脏手术患者心脏事件及围手术期处理之双中心调查。
Pub Date : 2003-12-01
Kin-Shing Poon, Ming-Chien Lee, Min-Wen Yang, Wen-Kuei Chang, Chia-Chen Chen, King-Chuen Wu, Rick Sai-Chuen Wu

Background: The risk of cardiac patients undergoing noncardiac surgery is relatively high. Successful preoperative evaluation and perioperative anesthetic management of a patient require a good communication among the patient, the anesthesiologist and the surgeon as well as excellent cooperation between the surgeon and anesthesiologist with a tacit understanding of the peri-operative risks. Peri-operative risk factors have been readily investigated in Caucasians or Westerners. As different ethnic populations may have different risk factors for a same disease entity, understanding the uniqueness in this respect in Taiwanese is mandatory. The purpose of this study is to examine the risk factors, perioperative cardiac events and the qualities of preoperative preparation and post-operative intensive care in Taiwanese cardiac patients undergoing noncardiac surgery.

Methods: Two medical centers in Taiwan worked out a set of prospective questionnaire to evaluate the preoperative preparation, intraoperative events, and postoperative care of cardiac patients undergoing noncardiac surgery in these hospitals.

Results: Between March 2002 and May 2002, there were 196 cardiac patients undergoing noncardiac surgery out of a total of 10,129 anesthetized surgical patients in two medical centers. The risk factors of these patients included coronary artery disease, hypertension, diabetes mellitus, congestive heart failure, arrhythmia, and renal function impairment. In these 196 cases, only 26.5% (52) and 16.8% (33) had been preoperatively evaluated by cardiologist and anesthesiologist respectively through consultation. The number of pre-operation specific cardiac tests totaled 34, and 41 patients (20.9%) required post-operative intensive care. There were two peri-operative fatalities and fourteen peri-operative cardiac events.

Conclusions: The quality of care for preoperative evaluation and quality assurance need to be improved in Taiwan.

背景:心脏病患者接受非心脏手术的风险相对较高。成功的患者术前评估和围手术期麻醉管理需要患者、麻醉师和外科医生之间的良好沟通,以及外科医生和麻醉师之间的良好合作,对围手术期的风险有默契的了解。围手术期危险因素已在白种人或西方人中进行了调查。由于不同族群对于同一种疾病可能有不同的危险因素,了解台湾人在这方面的独特性是必要的。摘要本研究旨在探讨台湾地区接受非心脏手术之心脏病患之危险因素、围术期心脏事件、术前准备及术后重症监护之品质。方法:台湾两家医疗中心编制一套前瞻性问卷,评估在医院接受非心脏手术的心脏病患者的术前准备、术中事件及术后护理。结果:2002年3月至2002年5月,在两个医疗中心共10,129名麻醉手术患者中,有196名心脏患者接受了非心脏手术。这些患者的危险因素包括冠状动脉疾病、高血压、糖尿病、充血性心力衰竭、心律失常和肾功能损害。在这196例患者中,分别只有26.5%(52例)和16.8%(33例)接受了心内科医生和麻醉科医生的术前会诊评估。术前特异性心脏检查34例,41例(20.9%)患者需要术后重症监护。2例围手术期死亡,14例围手术期心脏事件。结论:台湾地区术前评估护理质量及质量保证有待提高。
{"title":"A two-center survey of cardiac events and peri-operative managements of cardiac patients undergoing non-cardiac surgery in Taiwanese population.","authors":"Kin-Shing Poon,&nbsp;Ming-Chien Lee,&nbsp;Min-Wen Yang,&nbsp;Wen-Kuei Chang,&nbsp;Chia-Chen Chen,&nbsp;King-Chuen Wu,&nbsp;Rick Sai-Chuen Wu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The risk of cardiac patients undergoing noncardiac surgery is relatively high. Successful preoperative evaluation and perioperative anesthetic management of a patient require a good communication among the patient, the anesthesiologist and the surgeon as well as excellent cooperation between the surgeon and anesthesiologist with a tacit understanding of the peri-operative risks. Peri-operative risk factors have been readily investigated in Caucasians or Westerners. As different ethnic populations may have different risk factors for a same disease entity, understanding the uniqueness in this respect in Taiwanese is mandatory. The purpose of this study is to examine the risk factors, perioperative cardiac events and the qualities of preoperative preparation and post-operative intensive care in Taiwanese cardiac patients undergoing noncardiac surgery.</p><p><strong>Methods: </strong>Two medical centers in Taiwan worked out a set of prospective questionnaire to evaluate the preoperative preparation, intraoperative events, and postoperative care of cardiac patients undergoing noncardiac surgery in these hospitals.</p><p><strong>Results: </strong>Between March 2002 and May 2002, there were 196 cardiac patients undergoing noncardiac surgery out of a total of 10,129 anesthetized surgical patients in two medical centers. The risk factors of these patients included coronary artery disease, hypertension, diabetes mellitus, congestive heart failure, arrhythmia, and renal function impairment. In these 196 cases, only 26.5% (52) and 16.8% (33) had been preoperatively evaluated by cardiologist and anesthesiologist respectively through consultation. The number of pre-operation specific cardiac tests totaled 34, and 41 patients (20.9%) required post-operative intensive care. There were two peri-operative fatalities and fourteen peri-operative cardiac events.</p><p><strong>Conclusions: </strong>The quality of care for preoperative evaluation and quality assurance need to be improved in Taiwan.</p>","PeriodicalId":79312,"journal":{"name":"Acta anaesthesiologica Sinica","volume":"41 4","pages":"173-8"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24206597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sudden complete obstruction of breathing circuit during postural change upon completion of thoracic spinal surgery in a pediatric patient. 小儿胸椎手术完成后体位改变时呼吸回路突然完全阻塞。
Pub Date : 2003-09-01
Ying-Ming Wang, Cheng-Show Chen, Nien-Chun Chung, Xuan-De Ye, Kang Liu

Positioning patients during the perioperative period is a common event to anesthesiologists. A variety of complications may arise during this cumbrous moment. We describe a rare circumstance that we came across immediately after changing the posture of a pediatric patient at the end of thoracic spinal surgery. A total occlusion of the combined heat-moisture exchanger (HME) and bacterial/viral filter was responsible for breathing circuit obstruction. The use of the combined HME and bacterial/viral filter is not entirely riskless during general anesthesia.

麻醉医师在围手术期给病人定位是一件常见的事情。在这个复杂的时刻,可能会出现各种各样的并发症。我们描述了一个罕见的情况,我们遇到了改变姿势后立即儿科病人在胸椎手术结束。复合热湿交换器(HME)和细菌/病毒过滤器的完全闭塞是导致呼吸回路阻塞的原因。在全身麻醉期间,联合使用HME和细菌/病毒过滤器并非完全没有风险。
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引用次数: 0
General anesthesia for patients with automatic implantable cardioverter defibrillator in place--a case report. 自动植入式心律转复除颤器就位患者全身麻醉1例报告。
Pub Date : 2003-09-01
Min-Ho Chan, Yen-Chin Liu, Ben-Shiang Deng, Kang Liu

Automatic implantable cardioverter defibrillator (AICD) was commercially available for use in patients with malignant ventricular tachycardia and ventricular fibrillation since its meeting with FDA approval in 1985. The number of AICD implantation has increased year by year worldwide. It was allowed to be used in clinical setting in Taiwan by the Department of Health in April 1997. Physicians may come across patients with an implanted AICD undergoing surgery unrelated to cardiac issues more frequently. It is also a new challenge to anesthesiologists who must make pre-operative evaluation, maintenance during operative period and post-operative re-evaluation of the AICD function. We bring forward here for discussion a 72-year-old male patient who underwent non-cardiac surgery with AICD implantation under general anesthesia. The anesthetic precautions of patients with the device are also touched.

自1985年获得FDA批准以来,自动植入式心律转复除颤器(AICD)在商业上可用于恶性室性心动过速和心室颤动患者。在世界范围内,AICD的植入数量逐年增加。1997年4月,卫生部批准在台湾临床使用。医生可能会更频繁地遇到植入AICD的患者进行与心脏问题无关的手术。这对麻醉医师也是一个新的挑战,他们必须对AICD的术前评估、术中维护和术后再评估。我们在此提出一位72岁男性患者,在全身麻醉下接受非心脏手术并植入AICD。并介绍了使用该装置的患者的麻醉注意事项。
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引用次数: 0
Hypercapnia due to rupture of the unidirectional valve in the inspiratory limb of the breathing system after induction of general anesthesia--a case report. 全麻诱导后呼吸系统吸气肢单向阀破裂致高碳酸血症1例
Pub Date : 2003-09-01 DOI: 10.6955/AAS.200309.0139
Shinn-Long Lin, C. Yeh, Chueng-He Lu, S. Ho, Chih-Shung Wong
Malfunction of either inspiratory or expiratory check valve in a breathing circuit system may allow carbon dioxide (CO2) rebreathing and result in hypercapnia. The subsequent increase of PaCO2 may entail increased sympathetic activity which in turn causes serious problems such as tachyarrhythmia and myocardial ischemia, particularly in patients who have history of coronary artery disease (CAD). Here, we report an incident of rupture of the inspiratory valve in the breathing circuit which happened to a patient during induction of general anesthesia and eventuated in markedly heightened end-tidal CO2 (EtCO2) of the patient. The recognition, related complications and management of the inspiratory valve malfunction are discussed.
呼吸回路系统中吸气或呼气止回阀的故障可能导致二氧化碳(CO2)再呼吸并导致高碳酸血症。随后的PaCO2升高可能导致交感神经活动增加,进而导致严重的问题,如心动过速和心肌缺血,特别是有冠状动脉疾病(CAD)病史的患者。在此,我们报告了一例在全麻诱导过程中发生的呼吸回路吸气阀破裂事件,最终导致患者潮末CO2 (EtCO2)明显升高。本文讨论了吸气阀功能障碍的识别、并发症及处理方法。
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引用次数: 3
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Acta anaesthesiologica Sinica
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