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Physical Functioning and Depression Among Older Persons with Cancer 老年癌症患者的身体功能与抑郁
Pub Date : 2008-06-28 DOI: 10.1111/j.1523-5394.2001.91004.pp.x
Margot E. Kurtz ph d, J. C. Kurtz ph d, Manfred Stommel ph d, Charles W. Given ph d, Barbara Given ph d, rn, faan

Purpose: The purpose of this study was to help identify factors to assess which elderly patients are likely to experience problems with physical and psychological functioning in association with cancer or its treatment.

description of Study: A study was undertaken with a sample of 420 patients with cancer who were between the ages of 65 and 98 years and had received an incident diagnosis of breast, colon, lung, or prostate cancer. An analysis of covariance technique was used to determine how cancer site, treatment type, stage of disease, gender, age, comorbidity, symptom severity, and prediagnosis levels of physical functioning were related to physical functioning deficit, and how all of these in turn influenced patient depressive symptomatology.

Results: Prediagnosis physical functioning, symptom severity, and days since surgery were significant predictors of physical functioning deficit. Patients who had been treated only with surgery experienced greater physical functioning deficits than did patients who had received both surgery and adjuvant therapy. This apparent anomaly was partly explained by the time interval from surgery to interview. Higher levels of symptom severity, lower levels of prior physical functioning, and greater physical functioning deficits all predicted higher levels of depressive symptomatology.

clinical Implications: In the care of elderly patients with cancer, it is important for healthcare providers to consider the prediagnosis levels of physical functioning of patients with cancer to understand and anticipate the physical and psychological consequences of cancer and its treatment. Equally important is the proper management of patient symptoms in maximizing both the physical and psychological quality of life.

目的:本研究的目的是帮助确定因素,以评估哪些老年患者可能经历与癌症或其治疗相关的身体和心理功能问题。研究描述:本研究对420名年龄在65至98岁之间的癌症患者进行了研究,这些患者曾被诊断为乳腺癌、结肠癌、肺癌或前列腺癌。采用协方差分析技术确定癌症部位、治疗类型、疾病分期、性别、年龄、合并症、症状严重程度和身体功能的诊断前水平与身体功能缺陷之间的关系,以及所有这些因素如何反过来影响患者的抑郁症状。结果:诊断前躯体功能、症状严重程度和手术后天数是躯体功能缺陷的重要预测因素。仅接受手术治疗的患者比同时接受手术和辅助治疗的患者有更大的身体功能缺陷。这种明显的异常部分是由于从手术到面谈的时间间隔。症状严重程度越高,先前身体功能水平越低,身体功能缺陷越严重,都预示着抑郁症状的程度越高。临床意义:在老年癌症患者的护理中,医疗保健提供者考虑癌症患者身体功能的诊断前水平,以了解和预测癌症及其治疗的生理和心理后果是很重要的。同样重要的是对患者症状的适当管理,以最大限度地提高身体和心理生活质量。
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引用次数: 64
The Treatment of Prostate Cancer. 前列腺癌的治疗。
Pub Date : 2008-06-28 DOI: 10.1111/j.1523-5394.2001.96009.pp.x
Georgi Pirtskhalaishvili md, phd, Ronald L. Hrebinko md , Joel B. Nelson md

Purpose: The purpose of this report is to discuss the current treatment options available to the patient with prostate cancer in all stages of the disease.

Overview: With the exception of skin cancer, prostate cancer is the most common cancer in men in the United States. Most patients in the current era will present with organ-confined disease, amenable to curative treatment. Treatment for organ-confined disease includes watchful waiting, radical prostatectomy, radiation therapy, and cryosurgery in selective cases. Hormone therapy is the cornerstone of treatment of patients with advanced prostate cancer. There is no curative treatment for hormone-refractory prostate cancer.

Clinical implications: The availability of several therapeutic options for localized prostate cancer warrants careful consideration when planning treatment with curative intent. Patients need to be active participants in decision making, and they must be aware of the benefits and possible complications of the different types of treatment. Patients with advanced prostate cancer need to be aware that hormone treatment will provide temporization and palliation in the majority of cases. Hormone-resistant prostate cancer is refractory to most forms of conventional and experimental therapy.

目的:本报告的目的是讨论目前可用于前列腺癌所有阶段患者的治疗方案。概述:除皮肤癌外,前列腺癌是美国男性中最常见的癌症。在当今时代,大多数患者将表现为器官局限性疾病,可治愈治疗。器官局限性疾病的治疗包括观察等待、根治性前列腺切除术、放射治疗和选择性冷冻手术。激素疗法是晚期前列腺癌患者治疗的基石。对于激素难治性前列腺癌尚无治愈方法。临床意义:针对局限性前列腺癌的几种治疗方案在制定治疗方案时需要慎重考虑。患者需要积极参与决策,他们必须了解不同类型治疗的益处和可能的并发症。晚期前列腺癌患者需要意识到,激素治疗将提供时间和缓解在大多数情况下。激素抵抗性前列腺癌对大多数常规疗法和实验疗法都是难治性的。
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引用次数: 25
Reviewer Appreciation 评论家赞赏
Pub Date : 2008-06-28 DOI: 10.1111/j.1523-5394.2000.086rl.pp.x
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引用次数: 0
Resources on Colorectal Cancer for Patients 大肠癌患者资料
Pub Date : 2008-06-28 DOI: 10.1111/j.1523-5394.2000.86001.pp.x
Martha Crosier Wood mba , Catherine Tomeo Ryan mph
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引用次数: 0
Imatinib Mesylate: 甲磺酸伊马替尼:
Pub Date : 2008-06-28 DOI: 10.1111/j.1523-5394.2001.95003.pp.x
Kavita K. Parmar bsc(pharm), pharmd, Reginald S. King pharmd, bcop
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引用次数: 0
Celebrating Legacies 庆祝遗产
Pub Date : 2008-06-28 DOI: 10.1111/j.1523-5394.2000.86011.pp.x
Genevieve V. Foley RN, MSN, OCN, CNAA
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引用次数: 0
Communication Challenges in a Young Man with Hodgkin's Disease 何杰金氏病青年患者的沟通障碍
Pub Date : 2008-06-28 DOI: 10.1111/j.1523-5394.2001.96002.pp.x
Erin Medoff APRN, AOCN, Arlene D. Houldin PhD, CS, RN, Carrie Tompkins Stricker MSN, RN, CRNP, AOCN, Stephen Anderson PhD, Lisa Chertkov MD
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引用次数: 1
Response 2 回复2
Pub Date : 2008-06-28 DOI: 10.1111/j.1523-5394.2001.92006-3.pp.x
Ida M. Martinson RN, PhD, FAAN
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引用次数: 0
New Advances in the Management of Cutaneous T-Cell Lymphoma 皮肤T细胞管理的新进展 淋巴瘤
Pub Date : 2008-06-28 DOI: 10.1111/j.1523-5394.2001.91010.pp.x
Sallie K. Young BSc(pharm), pharm d
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引用次数: 0
Creating Comprehensive Cancer Care 创造全面的癌症 照顾
Pub Date : 2008-06-28 DOI: 10.1111/j.1523-5394.2001.91008.pp.x
James S. Gordon md
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引用次数: 2
期刊
Cancer practice
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