{"title":"Corneal transplant.","authors":"J. P. Lordan, B. Hills","doi":"10.32388/myfmma","DOIUrl":"https://doi.org/10.32388/myfmma","url":null,"abstract":"progress their to be hopeless","PeriodicalId":79832,"journal":{"name":"Clinical privilege white paper","volume":"31 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90835445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart failure is a condition that will affect 2-3% of the population. Around one third of the patients have a decreased LVEF and a widened QRS complex as a sign of ventricular dyssynchrony. CRT has emerged as a treatment that reduces morbidity, mortality and improve functional status in this population. However, a substantial amount of treated patients do not respond satisfactory after implantation. This thesis sought to assess characteristics and factors associated with long termmortality and outcome in a cohort of CRT patients. The thesis includes four papers: Paper i assessed the association between early subjective response after implantation and long term outcome in CRT-P patients. We found that those who exhibited a self-assessed positive therapy response after 1-2 months had a significantly better survival rate compared with those who did not. The second paper investigated long termmortality in CRT-P and primary prophylactic CRT-D patients. Patients with CRT-D had better crude survival rates than those with CRT-P. However, the CRT-P group was older and had more comorbidities. CRT-D was not significantly associated with better survival when adjusting for confounders, as compared to CRT-P. The third paper assessed a method of estimating myocardial scar burden from a standard 12-lead ECG (Selvester QRS score) in patients with Left Bundle Branch Block. 401 patients were assessed and divided into a high-score and a low-score group. The group with high Selvester QRS score was found to have a worse survival rate compared to the group of patients with lower scores. The last paper found that the CHA2DS2-VASc score, which is commonly used for stroke risk estimation in atrial fibrillation patients, was associated with long term mortality and a composite endpoint of mortality or hospitalization for heart failure in a CRT population. When comparing CHA2DS2-VASc to other, CRT-specific scores, it performed approximately as well in predicting mortality and the composite endpoint.
{"title":"Cardiac resynchronization therapy.","authors":"C. Reitan","doi":"10.32388/7hqr45","DOIUrl":"https://doi.org/10.32388/7hqr45","url":null,"abstract":"Heart failure is a condition that will affect 2-3% of the population. Around one third of the patients have a decreased LVEF and a widened QRS complex as a sign of ventricular dyssynchrony. CRT has emerged as a treatment that reduces morbidity, mortality and improve functional status in this population. However, a substantial amount of treated patients do not respond satisfactory after implantation. This thesis sought to assess characteristics and factors associated with long termmortality and outcome in a cohort of CRT patients. The thesis includes four papers: Paper i assessed the association between early subjective response after implantation and long term outcome in CRT-P patients. We found that those who exhibited a self-assessed positive therapy response after 1-2 months had a significantly better survival rate compared with those who did not. The second paper investigated long termmortality in CRT-P and primary prophylactic CRT-D patients. Patients with CRT-D had better crude survival rates than those with CRT-P. However, the CRT-P group was older and had more comorbidities. CRT-D was not significantly associated with better survival when adjusting for confounders, as compared to CRT-P. The third paper assessed a method of estimating myocardial scar burden from a standard 12-lead ECG (Selvester QRS score) in patients with Left Bundle Branch Block. 401 patients were assessed and divided into a high-score and a low-score group. The group with high Selvester QRS score was found to have a worse survival rate compared to the group of patients with lower scores. The last paper found that the CHA2DS2-VASc score, which is commonly used for stroke risk estimation in atrial fibrillation patients, was associated with long term mortality and a composite endpoint of mortality or hospitalization for heart failure in a CRT population. When comparing CHA2DS2-VASc to other, CRT-specific scores, it performed approximately as well in predicting mortality and the composite endpoint.","PeriodicalId":79832,"journal":{"name":"Clinical privilege white paper","volume":"33 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81629642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-31DOI: 10.1097/01241398-199209000-00024
Tomas B. Beckingsale, K. Ghosh
{"title":"Musculoskeletal oncology.","authors":"Tomas B. Beckingsale, K. Ghosh","doi":"10.1097/01241398-199209000-00024","DOIUrl":"https://doi.org/10.1097/01241398-199209000-00024","url":null,"abstract":"","PeriodicalId":79832,"journal":{"name":"Clinical privilege white paper","volume":"40 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2019-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86498598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01DOI: 10.1002/9781119554639.ch5
D. Semple, R. Smyth
This chapter covers child and adolescent psychiatry. From assessment, develop, resilience, and attachment, normal infant mental health is discussed, followed by an approach to behavioural problems and conduct disorders in the older child. Parent management training is covered, followed by individual disorders and their management in the context of the adolescent and child, from attention-deficit/hyperactivity disorder to psychosis. Special focus is given to children and young people with intellectual disabilities, child maltreatment, and prescribing differences from adult psychiatry.
{"title":"Child and adolescent psychiatry.","authors":"D. Semple, R. Smyth","doi":"10.1002/9781119554639.ch5","DOIUrl":"https://doi.org/10.1002/9781119554639.ch5","url":null,"abstract":"This chapter covers child and adolescent psychiatry. From assessment, develop, resilience, and attachment, normal infant mental health is discussed, followed by an approach to behavioural problems and conduct disorders in the older child. Parent management training is covered, followed by individual disorders and their management in the context of the adolescent and child, from attention-deficit/hyperactivity disorder to psychosis. Special focus is given to children and young people with intellectual disabilities, child maltreatment, and prescribing differences from adult psychiatry.","PeriodicalId":79832,"journal":{"name":"Clinical privilege white paper","volume":"22 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81539054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
It includes subjects generally not covered in other handbook series, especially many technology-driven topics that reflect the increasing influence of technology in clinical medicine. The name chosen for this comprehensive medical handbook series is Vademecum, a Latin word that roughly means “to carry along”. In the Middle Ages, traveling clerics carried pocket-sized books, excerpts of the carefully transcribed canons, known as Vademecum. In the 19th century a medical publisher in Germany, Samuel Karger, called a series of portable medical books Vademecum. The Vademecum books are intended to be used both in the training of physicians and the care of patients, by medical students, medical house staff and practicing physicians. We hope you will find them a valuable resource. Bone Marrow Transplantation 9. Growth Factors 10. Infections 11. Graft-Versus-Host Disease 12. Graft-Versus-Leukemia Effect of Allogeneic BMT 13. Toxicity 14. Outpatient Management of Marrow and Blood Stem Cell Transplant Patients 15. Gene Therapy 16. Medications Appendices
{"title":"Bone marrow transplantation.","authors":"P. McGrath","doi":"10.4324/9781315196459-6","DOIUrl":"https://doi.org/10.4324/9781315196459-6","url":null,"abstract":"It includes subjects generally not covered in other handbook series, especially many technology-driven topics that reflect the increasing influence of technology in clinical medicine. The name chosen for this comprehensive medical handbook series is Vademecum, a Latin word that roughly means “to carry along”. In the Middle Ages, traveling clerics carried pocket-sized books, excerpts of the carefully transcribed canons, known as Vademecum. In the 19th century a medical publisher in Germany, Samuel Karger, called a series of portable medical books Vademecum. The Vademecum books are intended to be used both in the training of physicians and the care of patients, by medical students, medical house staff and practicing physicians. We hope you will find them a valuable resource. Bone Marrow Transplantation 9. Growth Factors 10. Infections 11. Graft-Versus-Host Disease 12. Graft-Versus-Leukemia Effect of Allogeneic BMT 13. Toxicity 14. Outpatient Management of Marrow and Blood Stem Cell Transplant Patients 15. Gene Therapy 16. Medications Appendices","PeriodicalId":79832,"journal":{"name":"Clinical privilege white paper","volume":"4 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2019-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85423907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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