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Isolated External Iliac Artery Aneurysm with Fibromuscular Dysplasia. 孤立性髂外动脉瘤伴纤维肌肉发育不良。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-03-25 DOI: 10.3400/avd.cr.21-00137
Yusuke Shintani, Shinichi Hiromatsu, Kyouhei Yamada, Shinya Negoto, Tomoyuki Anegawa, Eiji Nakamura, Hiroyuki Ootsuka, Eiki Tayama

Isolated aneurysms of the external iliac artery are rare in patients with fibromuscular dysplasia. In this study, we report the case of a 74-year-old man with advanced gastric cancer who was found to have a medium-sized aneurysm of the external iliac artery (35 mm) on preoperative computed tomography angiograms. The patient underwent laparoscopic gastrectomy followed by replacement of the external iliac artery 6 months later. Histological examination of biopsy specimens revealed fibromuscular dysplasia. The 6 month postoperative course was uneventful. Such a case of external iliac artery aneurysm caused by fibromuscular dysplasia is very rare, and open surgery is recommended for its removal.

孤立的髂外动脉动脉瘤在纤维肌肉发育不良患者中是罕见的。在本研究中,我们报告一例74岁晚期胃癌患者,术前ct血管造影发现髂外动脉有一个中等大小的动脉瘤(35mm)。患者于6个月后行腹腔镜胃切除术并行髂外动脉置换术。活检标本的组织学检查显示纤维肌肉发育不良。术后6个月的过程平安无事。这种由纤维肌肉发育不良引起的髂外动脉瘤非常罕见,建议开腹手术切除。
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引用次数: 0
Feasibility of Simple Evaluation of Coronary Artery Calcium Using a Number of Chest Computed Tomography Slices: A Multicenter Study. 多中心研究:利用多层胸部计算机断层扫描片对冠状动脉钙化进行简单评估的可行性。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-03-25 DOI: 10.3400/avd.oa.22-00060
Hideya Yamamoto, Shinichiro Fujimoto, Chihiro Aoshima, Tohru Minamino, Takashi Fujii, Shinichi Wakabayashi, Yoji Urabe, Hironori Ueda, Eiji Kunita, Mitsunori Abe, Hiroshi Higashino

Objective: We aimed to evaluate the visual measurements of coronary artery calcium (CAC) on nonelectrocardiogram (ECG)-gated chest computed tomography (CT) using a simple scoring method that involves counting the number of CT slices containing CAC. Materials and Methods: We analyzed 163 participants who underwent both coronary and chest CT examinations at six centers within 3 months. Agatston scores were calculated on standard ECG-gated scans and classified as none (0), mild (1-99), moderate (100-400), or severe (>400). Next, chest CT images were reconstructed to standard 5.0 mm axial slices. Then, CAC on chest CT scans was measured using two methods: the Weston score (sum of the assigned score of each vessel, range: 0-12) and number of slices showing CAC (Ca-slice#). Results: When the Weston score and Ca-slice# were divided into four levels according to the optimal divisional levels corresponding to the Agatston score classes, good agreements with the 4-grade Agatston score were observed (kappa value=0.610 and 0.794, respectively). The sensitivity and specificity of Ca-slice# ≥9 to identify severe Agatston scores of >400 were 86% and 96%, respectively. Conclusion: The Ca-slice#, a simple scoring method using chest CT scans, was in good agreement with the ECG-gated Agatston score.

目的:我们旨在评估非心电图门控胸部计算机断层扫描(CT)上冠状动脉钙(CAC)的视觉测量,使用一种简单的评分方法,包括计算含有CAC的CT切片的数量。材料和方法:我们分析了163名参与者,他们在3个月内在6个中心接受了冠状动脉和胸部CT检查。在标准心电图门控扫描上计算Agatston评分,并将其分为无(0)、轻度(1-99)、中度(100-400)或重度(>400)。接下来,将胸部CT图像重建为标准的5.0 mm轴向切片。然后,使用两种方法测量胸部CT扫描上的CAC: Weston评分(每个血管分配评分的总和,范围:0-12)和显示CAC的切片数(ca切片#)。结果:将Weston评分和Ca-slice#按Agatston评分类别对应的最优划分水平分为4个等级,与4级Agatston评分吻合较好(kappa值分别为0.610和0.794)。Ca-slice#≥9对>400的重度Agatston评分的敏感性和特异性分别为86%和96%。结论:Ca-slice#是一种简单的胸部CT评分方法,与ecg门控Agatston评分吻合较好。
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引用次数: 0
A Novel Graft Route by Passage under the Achilles Tendon in Paramalleolar Distal Bypass Using the Small Saphenous Vein. 小隐静脉在踝旁远端旁路术中跟腱下通道的新型移植物路径。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-03-25 DOI: 10.3400/avd.cr.22-00103
Keisuke Kamada, Atsuhiro Koya, Keitaro Nakanishi, Kazunori Ishikawa, Masami Shingaki, Kiyohumi Morishita

A 77-year-old man with diabetes presented to our hospital because of left toe gangrene, requiring infrapopliteal revascularization. The patient was on hemodialysis for renal dysfunction. The great saphenous veins had been used for a previous coronary artery bypass. Hence, the small saphenous vein was applied in a popliteal-to-distal posterior tibial artery bypass. The vein graft was passed under the Achilles tendon to reduce graft length, preventing external compression around the ankle. We performed minor amputation and provided negative pressure wound therapy to promote ulcer healing. The wounds healed entirely after two months.

一名77岁男性糖尿病患者因左脚趾坏疽就诊于我院,需行腘下血管重建术。患者因肾功能不全正在进行血液透析。大隐静脉曾用于冠状动脉旁路手术。因此,小隐静脉应用于腘动脉至胫骨后动脉远端搭桥。静脉移植物在跟腱下通过,以减少移植物的长度,防止踝关节周围的外部压迫。我们进行了小截肢和负压伤口治疗,以促进溃疡愈合。两个月后伤口完全愈合了。
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引用次数: 0
Risk Factors and Impact on Outcomes of Thrombosis in Patients with COVID-19 in Japan: From the CLOT-COVID Study. 日本COVID-19患者血栓形成的危险因素及其对预后的影响:来自CLOT-COVID研究
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-03-25 DOI: 10.3400/avd.oa.22-00071
Sen Yachi, Makoto Takeyama, Yuji Nishimoto, Ichizo Tsujino, Junichi Nakamura, Naoto Yamamoto, Hiroko Nakata, Satoshi Ikeda, Michihisa Umetsu, Shizu Aikawa, Hiroya Hayashi, Hirono Satokawa, Yoshinori Okuno, Eriko Iwata, Yoshito Ogihara, Nobutaka Ikeda, Akane Kondo, Takehisa Iwai, Norikazu Yamada, Tomohiro Ogawa, Takao Kobayashi, Makoto Mo, Yugo Yamashita, On Behalf Of The Clot-Covid Study Investigators
Objectives: The relationship between the thrombotic event and prognosis in patients with coronavirus disease 2019 (COVID-19) has not yet been fully investigated in Japan. Our study aimed to investigate the clinical outcomes and risk factors for thrombosis in hospitalized patients with COVID-19 in Japan. Materials and Methods: We compared the patient characteristics and clinical outcomes among patients with thrombosis (N=55) and those without thrombosis (N=2839) by using a large-scale data of CLOT-COVID study (thrombosis and antiCoaguLatiOn Therapy in patients with COVID-19 in Japan Study: UMIN000045800). Thrombosis included venous thromboembolism, ischemic stroke, myocardial infarction, and systemic arterial thromboembolism. Results: Higher rates of mortality and bleeding events were shown in hospitalized patients with COVID-19 with thrombosis compared to those without thrombosis (all-cause mortality, 23.6% vs. 5.1%, P<0.001; major bleeding, 23.6% vs. 1.6%, P<0.001). Multivariable analysis revealed that the independent risk factors of thrombosis were male sex, D-dimer level on admission>1.0 µg/mL, and moderate and severe COVID-19 status on admission. Conclusions: The development of thrombosis in hospitalized patients with COVID-19 was related to higher mortality and major bleeding, and several independent risk factors for thrombosis could help determine the patient-appropriate treatment for COVID-19.
目的:日本冠状病毒病2019 (COVID-19)患者血栓形成事件与预后的关系尚未得到充分研究。本研究旨在调查日本新冠肺炎住院患者血栓形成的临床结局和危险因素。材料与方法:我们采用CLOT-COVID研究(日本COVID-19患者血栓形成和抗凝治疗研究:UMIN000045800)的大规模数据,比较血栓形成患者(N=55)和无血栓形成患者(N=2839)的患者特征和临床结局。血栓形成包括静脉血栓栓塞、缺血性中风、心肌梗死和全身动脉血栓栓塞。结果:合并血栓形成的COVID-19住院患者的死亡率和出血事件发生率高于未合并血栓形成的患者(全因死亡率,23.6% vs. 5.1%, P1.0µg/mL,入院时为中重度COVID-19状态)。结论:住院COVID-19患者血栓形成与较高的死亡率和大出血有关,血栓形成的几个独立危险因素可以帮助确定适合患者的COVID-19治疗方案。
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引用次数: 0
Incidence, Risk Factors, and Treatment of Venous Thromboembolism after a Serious Disaster: The Kumamoto Twin Earthquakes. 重大灾害后静脉血栓栓塞的发生率、危险因素和治疗:熊本双地震。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-03-25 DOI: 10.3400/avd.oa.22-00095
Eiji Taguchi, Kazuhiro Nishigami, Junichi Maehara, Yutaka Konami, Masayuki Inoue, Hiroto Suzuyama, Kazuhisa Kodama, Takashi Unoki, Yoko Horibata, Tadashi Sawamura, Koichi Nakao, Tomohiro Sakamoto, Junjiro Koyama

Objective: On April 16, 2016, earthquakes struck Kumamoto. In this report, the incidence and treatment of venous thromboembolism (VTE) in patients presenting to our hospital are summarized. Materials and Methods: We reviewed the details of 22 consecutive patients who were diagnosed with VTE at our hospital during the 2 weeks after the earthquakes. Results: Nineteen of the 22 patients stayed in their cars overnight after the earthquakes. Particularly, during the first 4 days, seven consecutive patients were hospitalized for pulmonary thromboembolism. All seven patients had sheltered in their cars after the earthquakes. The two patients transported on days 2.42 and 3.54 were the most severe cases. One patient was admitted after emergency initiation of venoarterial extracorporeal membrane oxygenation for treatment of hemodynamic collapse, whereas the other patient was admitted after resuscitation. By contrast, deep vein thrombosis (DVT) alone occurred within 5-9 days of the earthquakes. Bilateral DVT was the most common, which was followed by DVT on the right side only. Conclusion: The incidence of VTE might be higher after an earthquake, and an overnight stay in a car might be a risk factor for VTE. Stable patients based on the D-dimer concentration can be managed with nonwarfarin oral anticoagulants.

目的:2016年4月16日,熊本发生地震。本文就我院静脉血栓栓塞症(VTE)的发生率及治疗进行综述。材料与方法:我们回顾了22例地震后2周内在我院连续诊断为静脉血栓栓塞的患者的详细资料。结果:地震发生后,22名患者中有19人在车内过夜。特别是,在头4天,连续7名患者因肺血栓栓塞住院。地震后,七名病人都躲在自己的车里。第2.42和3.54天转运的2例患者为最严重病例。1例患者急诊启动静脉体外膜氧合治疗血流动力学衰竭后入院,另1例患者复苏后入院。相比之下,仅深静脉血栓形成(DVT)就在地震后5-9天内发生。双侧DVT最常见,其次为右侧DVT。结论:地震后静脉血栓栓塞的发生率可能较高,而在车内过夜可能是发生静脉血栓栓塞的危险因素。基于d -二聚体浓度的稳定患者可以使用非华法林口服抗凝剂。
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引用次数: 0
External Validation of the Padua and IMPROVE-VTE Risk Assessment Models for Predicting Venous Thromboembolism in Hospitalized Adult Medical Patients: A Retrospective Single-Center Study in Japan. Padua和improvement - vte风险评估模型用于预测住院成人患者静脉血栓栓塞的外部验证:日本的一项回顾性单中心研究
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-03-25 DOI: 10.3400/avd.oa.22-00108
Daichi Arakaki, Mitsunaga Iwata, Teruhiko Terasawa

Objectives: To assess the external validity of the Padua and International Medical Prevention Registry on Venous Thromboembolism (IMPROVE-VTE) risk assessment models (RAMs) for predicting venous thromboembolism (VTE) within 90 days of admission among hospitalized medical patients in Japan. Materials and Methods: A university hospital cohort comprising 3876 consecutive patients ages ≥15 years admitted to a general internal medicine department between July 2016 and July 2021 was retrospectively analyzed using data extracted from their medical records. Results: A total of 74 VTE events (1.9%), including six cases with pulmonary embolism (0.2%), were observed. Both RAMs had poor discriminative performance (C-index=0.64 for both) and generally underestimated VTE risks. However, recalibrating the IMPROVE-VTE RAM to update the baseline hazard improved the calibration (calibration slope=1.01). Decision curve analysis showed that a management strategy with no prediction model outperformed a clinical management strategy guided by the originally proposed RAMs. Conclusions: Both RAMs require an update to function in this particular setting. Further studies with a larger-sized cohort, including re-estimation of the individual regression coefficients with additional, more context-specific predictors, are needed to create a useful model that would help advance risk-oriented VTE prevention programs.

目的:评估帕多瓦和国际医学预防登记处静脉血栓栓塞(改善)风险评估模型(RAMs)在日本住院医疗患者入院90天内预测静脉血栓栓塞(VTE)的外部有效性。材料和方法:对2016年7月至2021年7月在普通内科连续就诊的3876例年龄≥15岁的大学医院队列患者进行回顾性分析,提取其病历数据。结果:共观察到静脉血栓栓塞74例(1.9%),其中肺栓塞6例(0.2%)。两个RAMs的判别性能较差(C-index=0.64),并且普遍低估了VTE风险。然而,重新校准IMPROVE-VTE RAM以更新基线危害改善了校准(校准斜率=1.01)。决策曲线分析表明,没有预测模型的管理策略优于最初提出的RAMs指导下的临床管理策略。结论:两个ram都需要更新才能在此特定设置中发挥作用。进一步的研究需要更大规模的队列,包括重新估计个体回归系数,使用额外的,更具体的预测因子,以创建一个有用的模型,有助于推进以风险为导向的静脉血栓栓塞预防计划。
{"title":"External Validation of the Padua and IMPROVE-VTE Risk Assessment Models for Predicting Venous Thromboembolism in Hospitalized Adult Medical Patients: A Retrospective Single-Center Study in Japan.","authors":"Daichi Arakaki,&nbsp;Mitsunaga Iwata,&nbsp;Teruhiko Terasawa","doi":"10.3400/avd.oa.22-00108","DOIUrl":"https://doi.org/10.3400/avd.oa.22-00108","url":null,"abstract":"<p><p><b>Objectives:</b> To assess the external validity of the Padua and International Medical Prevention Registry on Venous Thromboembolism (IMPROVE-VTE) risk assessment models (RAMs) for predicting venous thromboembolism (VTE) within 90 days of admission among hospitalized medical patients in Japan. <b>Materials and Methods:</b> A university hospital cohort comprising 3876 consecutive patients ages ≥15 years admitted to a general internal medicine department between July 2016 and July 2021 was retrospectively analyzed using data extracted from their medical records. <b>Results:</b> A total of 74 VTE events (1.9%), including six cases with pulmonary embolism (0.2%), were observed. Both RAMs had poor discriminative performance (C-index=0.64 for both) and generally underestimated VTE risks. However, recalibrating the IMPROVE-VTE RAM to update the baseline hazard improved the calibration (calibration slope=1.01). Decision curve analysis showed that a management strategy with no prediction model outperformed a clinical management strategy guided by the originally proposed RAMs. <b>Conclusions:</b> Both RAMs require an update to function in this particular setting. Further studies with a larger-sized cohort, including re-estimation of the individual regression coefficients with additional, more context-specific predictors, are needed to create a useful model that would help advance risk-oriented VTE prevention programs.</p>","PeriodicalId":7995,"journal":{"name":"Annals of vascular diseases","volume":"16 1","pages":"60-68"},"PeriodicalIF":0.8,"publicationDate":"2023-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/78/86/avd-16-1-oa.22-00108.PMC10064295.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9240251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-Time Assessment of Tissue Oxygen Saturation Using a Novel Oximeter During Revascularization for Acute Limb Ischemia: A Case Report. 在急性肢体缺血血运重建术中使用新型血氧仪实时评估组织氧饱和度:1例报告。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-03-25 DOI: 10.3400/avd.cr.22-00062
Tatsuro Yata, Masaki Sano, Kazunori Inuzuka, Kazuto Katahashi, Ena Naruse, Takafumi Kayama, Yuta Yamanaka, Hajime Tsuyuki, Yusuke Endo, Nozomu Ishikawa, Hiroya Takeuchi, Naoki Unno

Emergency surgery was performed to treat acute lower limb ischemia caused by heart thromboembolism and concomitant popliteal artery aneurysm. Using a near-infrared spectroscopy oximeter, regional tissue oxygen saturation (rSO2) was monitored to assess the tissue perfusion pre-, intra-, and postoperatively. rSO2 values did not increase sufficiently following thromboembolectomy of the superficial femoral artery, but they dramatically recovered after additional popliteal-anterior tibial bypass surgery. The affected limb was successfully salvaged. rSO2 monitoring was easily measured intraoperatively, which might be beneficial in evaluating tissue perfusion in patients with acute limb ischemia.

急诊手术治疗由心脏血栓栓塞及伴发腘动脉动脉瘤引起的急性下肢缺血。采用近红外光谱血氧仪监测局部组织血氧饱和度(rSO2),评估术前、术中、术后组织灌注。在股浅动脉血栓栓塞切除术后,rSO2值没有充分增加,但在额外的腘-胫骨前搭桥手术后,rSO2值显著恢复。患肢被成功抢救。术中监测rSO2简便,有助于评估急性肢体缺血患者的组织灌注情况。
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引用次数: 0
Paradox of the Relationship between Cardio-Ankle Vascular Index and Ankle-Brachial Index in Patients with Lower Extremity Artery Disease 下肢动脉疾病患者心踝血管指数与踝肱指数关系的悖论
Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-01-01 DOI: 10.3400/avd.avd.oa.23-00055
Yoko Sotoda, Shigeki Hirooka, Hiroyuki Orita, Ichiro Wakabayashi
Objectives: Measurements of ankle-brachial index (ABI) and toe-brachial index (TBI) are standard examinations for evaluating arterial blood flow in lower extremities and diagnosing lower extremity artery disease (LEAD). It remains to be clarified whether cardio-ankle vascular index (CAVI), a blood pressure-independent parameter of arterial stiffness, is associated with ABI and TBI in patients with LEAD.
目的:测量踝肱指数(ABI)和趾肱指数(TBI)是评估下肢动脉血流和诊断下肢动脉疾病(LEAD)的标准检查。心踝血管指数(CAVI),一个与血压无关的动脉硬度参数,是否与铅患者的ABI和TBI相关,仍有待澄清。
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引用次数: 0
Intraoperative Heparin Resistance after Administration of Andexanet Alfa to Manage an Internal Iliac Artery Aneurysm Rupture: A Case Report 术中应用安德沙内治疗髂内动脉瘤破裂后肝素抵抗1例
Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-01-01 DOI: 10.3400/avd.avd.cr.23-00060
Kanetsugu Nagao, Shigeyuki Yamashita, Rina Ebe, Norihito Naruto, Hisakatsu Ito, Saori Nagura, Toshio Doi, Kazuaki Fukahara, Naoki Yoshimura
Antithrombotic agents are increasingly prescribed to older adults; however, they are associated with bleeding-related complications. We describe a case of intraoperative heparin resistance after administration of andexanet alfa (AA). An 81-year-old man was diagnosed with a ruptured internal iliac artery aneurysm. The patient required emergency endovascular aneurysm repair and was treated with AA because he was receiving apixaban. Despite high-dose intraoperative heparin administration, his activated coagulation time was not prolonged. Our findings suggest that AA should be administered with caution in patients experiencing potentially fatal bleeding (requiring surgical intervention) who are also receiving direct oral anticoagulants.
抗血栓药物越来越多地用于老年人;然而,它们与出血相关的并发症有关。我们描述了一例术中肝素抵抗后给予阿德沙奈(AA)。一位81岁的男性被诊断为髂内动脉瘤破裂。患者需要紧急血管内动脉瘤修复,并接受AA治疗,因为他正在接受阿哌沙班。尽管术中给予大剂量肝素治疗,患者的激活凝血时间并未延长。我们的研究结果表明,对于有潜在致命性出血(需要手术干预)且同时接受直接口服抗凝剂的患者,应谨慎使用AA。
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引用次数: 0
Growing Renal Vein Aneurysm Treated by Endovascular Repair: A Case Report and Literature Review. 血管内修复术治疗生长期肾静脉动脉瘤:病例报告和文献综述。
IF 0.6 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2023-01-01 Epub Date: 2023-11-14 DOI: 10.3400/avd.avd.cr.23-00041
Hisao Nagato, Makoto Wakamiya, Kiyosumi Maeda, Kazuhiko Doi, Hiromasa Kira, Koji Ueyama

Renal vein aneurysm (RVA) is extremely rare and often asymptomatic, disclosed only incidentally on diagnostic imaging modalities such as computed tomography and ultrasonography. Management is often just watchful follow-up, but some patients require intervention. We present the case of a 74-year-old man complaining of lower back pain in whom a 53-mm RVA was identified. He underwent successful endovascular repair using Amplatzer vascular plugs. The aneurysm had completely resolved by 12 months. Endovascular treatment of a primary RVA does not seem to have been reported previously. This is a milestone case in the management of RVA.

肾静脉瘤(RVA)极为罕见,通常无症状,仅在计算机断层扫描和超声波检查等影像诊断方法中偶然发现。治疗方法通常只是观察随访,但有些患者需要介入治疗。我们介绍了一例 74 岁男性患者的病例,他主诉下背部疼痛,经检查发现有一个 53 毫米的 RVA。他使用 Amplatzer 血管塞成功接受了血管内修复手术。12 个月后,动脉瘤完全消退。血管内治疗原发性 RVA 之前似乎还没有报道过。这是治疗 RVA 的一个里程碑病例。
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引用次数: 0
期刊
Annals of vascular diseases
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