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Glucagon-Like Peptide-1 (GLP-1) Agonists may Warrant Revival of Preemptive Pharmacologic Prokinesis Preoperatively till Bring Your Own Ultrasonographic Stethoscope (BYoUS) Policy Becomes the Norm 胰高血糖素样肽-1 (GLP-1) 激动剂可能需要在自备超声听诊器 (BYoUS) 政策成为规范之前,恢复术前预防性药物促肾上腺皮质激素的作用
IF 0.9 Q2 Medicine Pub Date : 2024-01-12 DOI: 10.4103/aca.aca_137_23
Deepak Gupta
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引用次数: 0
Perioperative Challenges and Outcome After Surgical Correction of Post-myocardial Infarction Ventricular Septal Rupture: A Retrospective Single Center Study 心肌梗死后室间隔破裂手术矫正的围手术期挑战和结果:单中心回顾性研究
IF 0.9 Q2 Medicine Pub Date : 2024-01-12 DOI: 10.4103/aca.aca_75_23
Kedar Bangal
ABSTRACT Background: Ventricular septal rupture (VSR) is a rare but grave complication of acute myocardial infarction (AMI). It is a mechanical complication of myocardial infarction where patients may present either in a compensated state or in cardiogenic shock. The aim of the study is to determine the in-hospital mortality. The study also aims to identify the predictors of outcomes (in-hospital mortality, vasoactive inotrope score (VIS), duration of ICU stay and mechanical ventilation in the postoperative period) and compare the clinical and surgical parameters between survivors and non-survivors. Methods: This is a retrospective study. The data of 90 patients was collected from the medical records and the data comprising of 13 patients who underwent VSR closure by single patch technique, or septal occluder, and those who expired before receiving the treatment, was excluded. The data of 77 patients diagnosed with post-AMI VSR and who underwent surgical closure of VSR by double patch technique was included in this study. Clinical findings and echocardiography parameters were recorded from the perioperative period. The statistical software used was SPSS version 27. The primary outcome was determining the in-hospital mortality. The secondary outcome was identifying the clinical parameters that are significantly more in the non-survivors, and the factors predicting the in-hopsital mortality and morbidity (increased duration of ICU stay, and of mechanical ventilation, postoperative requirement of high doses of vasopressors and inotropes). Subgroup analysis was done to identify the relation of various clinical parameters with the postoperative complications. The factors predicting the in-hospital mortality were illustrated by a forest plot. Results: The mean age of the patients was 60.35 (±9.9) years, 56 (72.7%) were males, and 21 (27.3%) were females. Requirement of mechanical ventilation preoperatively (OR 3.92 [CI 2.91-6.96]), cardiogenic shock at presentation (OR 4 [CI 2.33 – 6.85]), requirement of IABP (OR 2.05 [CI 1.38-3.94]), were predictors of mortality. The apical location of VSR had been favorable for survival. The EUROScore II at presentation correlated with the postoperative VIS (level of significance [LS] 0.0011, R 0.36. The in-hospital mortality in this study was 33.76%. Conclusion: The in-hospital mortality of VSR is 33.76%. Cardiogenic shock at presentation, non-apical site of VSR, preoperative requirement of mechanical ventilation, high VIS preoperatively, perioperative utilization of IABP, prolonged CPB time, postoperative duration of mechanical ventilation, and high postoperative VIS were the factors associated with increased odds of in-hospital mortality.
摘要 背景:室间隔破裂(VSR)是急性心肌梗死(AMI)的一种罕见但严重的并发症。它是心肌梗死的一种机械性并发症,患者可能出现代偿状态或心源性休克。研究的目的是确定院内死亡率。研究还旨在确定预测结果的因素(院内死亡率、血管活性肌力素评分(VIS)、重症监护室住院时间和术后机械通气),并比较幸存者和非幸存者的临床和手术参数。方法:这是一项回顾性研究:这是一项回顾性研究。研究人员从病历中收集了 90 名患者的数据,并排除了 13 名通过单补片技术或房间隔封堵器进行 VSR 封堵的患者数据,以及在接受治疗前死亡的患者数据。本研究纳入了 77 名确诊为急性心肌梗死后 VSR 并通过双补片技术进行 VSR 手术封堵的患者数据。研究记录了围手术期的临床表现和超声心动图参数。使用的统计软件为 SPSS 27 版本。主要结果是确定院内死亡率。次要结果是确定非存活者中明显偏高的临床参数,以及预测院内死亡率和发病率的因素(重症监护室住院时间延长、机械通气时间延长、术后需要大剂量血管加压药和肌注)。为确定各种临床参数与术后并发症的关系,进行了分组分析。预测院内死亡率的因素通过森林图进行了说明。结果患者的平均年龄为 60.35(±9.9)岁,56(72.7%)人为男性,21(27.3%)人为女性。术前需要机械通气(OR 3.92 [CI 2.91-6.96])、发病时心源性休克(OR 4 [CI 2.33-6.85])、需要使用 IABP(OR 2.05 [CI 1.38-3.94])是预测死亡率的因素。VSR的心尖位置对存活有利。发病时的EUROScore II与术后VIS相关(显著性水平[LS] 0.0011,R 0.36)。本研究的院内死亡率为 33.76%。结论VSR 的院内死亡率为 33.76%。发病时的心源性休克、VSR 的非心尖部位、术前需要机械通气、术前 VIS 高、围手术期使用 IABP、CPB 时间延长、术后机械通气时间以及术后 VIS 高是增加院内死亡率的相关因素。
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引用次数: 0
Continuous Bilateral Transversus Thoracicmuscle Plane Block: An Analgesia Boon for Scoliotic Patients Undergoing Cardiac Surgery 连续双侧胸肌横断面阻滞:接受心脏手术的脊柱侧凸患者的镇痛福音
IF 0.9 Q2 Medicine Pub Date : 2024-01-12 DOI: 10.4103/aca.aca_47_23
Avneet Singh, Indumati, Dheeraj Kapoor, Suman Dhillon, Jasmine K. Narula, Sidharth Garg
ABSTRACT A person with thoracolumbar scoliosis for cardiac surgery presents with problems of restrictive lung disease with the additional risk of reduced lung compliance and respiratory complications compared to the other patients. Post-operative analgesia in the form of continuous bilateral transversus thoracic muscle plane block (TTMPB) may help such patients in early respiratory rehabilitation by decreasing the time to extubation, reducing the opioid requirement, and early initiation of physiotherapy decreasing the risk of complications.
摘要 胸腰椎侧弯患者在接受心脏手术时会出现限制性肺部疾病的问题,与其他患者相比,会增加肺顺应性降低和呼吸系统并发症的风险。术后连续双侧胸横肌平面阻滞(TTMPB)镇痛可以缩短拔管时间、减少阿片类药物的用量、尽早开始物理治疗以降低并发症风险,从而帮助这类患者尽早进行呼吸康复。
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引用次数: 0
Congenital Sub-Mitral Aneurysm: Anesthetics and Surgical Management 先天性髋臼下动脉瘤:麻醉和手术管理
IF 0.9 Q2 Medicine Pub Date : 2024-01-12 DOI: 10.4103/aca.aca_39_23
Jitendra Kalbande, Subrata S. Singha, N. Bodhey, Preetam Sahani
ABSTRACT A sub-mitral left ventricular aneurysm is a rare condition. It is a congenital outpouching of the left ventricular wall, invariably occurring adjacent to the posterior mitral leaflet. Sub-mitral aneurysm (SMA) has usually been reported as a consequence of myocardial ischemia (MI), rheumatic heart disease, tuberculosis, and infective endocarditis. Nevertheless, there have been few case reports of congenital SMA in India. It usually presents with symptoms of heart failure. We report a rare case of congenital SMA in a 27-year-old young Indian and its successful management through a trans-aneurysmal approach.
摘要 二尖瓣下左心室动脉瘤是一种罕见病。它是左心室壁的先天性外翻,通常发生在二尖瓣后叶附近。据报道,二尖瓣下动脉瘤(SMA)通常是心肌缺血(MI)、风湿性心脏病、结核病和感染性心内膜炎的结果。然而,印度很少有先天性 SMA 的病例报告。它通常表现为心力衰竭症状。我们报告了一例罕见的先天性 SMA 病例,患者是一名 27 岁的印度年轻人,通过经动脉瘤途径成功治愈了该病。
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引用次数: 0
Coronary Artery Aneurysm with Fistula Associated with Tricuspid Valve Regurgitation 三尖瓣反流伴有瘘管的冠状动脉动脉瘤
IF 0.9 Q2 Medicine Pub Date : 2024-01-12 DOI: 10.4103/aca.aca_60_23
F. A. Donoo, Faris Alghamdi, Abdul Basit Mir, Fahad Alkhedhairi
ABSTRACT Aneurysmal dilation of coronary arteries is a rare condition detected during coronary angiography. Due to their poorly elucidated underlying mechanisms, their variable presentations, and the lack of large-scale outcome data on their various treatment modalities, coronary artery aneurysms, and coronary ectasia pose a challenge to the managing clinician. This case presentation provides insight into the challenges regarding the management of the coronary artery aneurysm during the perioperative period.
摘要 冠状动脉瘤样扩张是冠状动脉造影术中发现的一种罕见疾病。冠状动脉瘤和冠状动脉异位症的基本机制尚未阐明,表现各异,且缺乏各种治疗方法的大规模结果数据,因此给临床医生的管理带来了挑战。本病例介绍了围手术期冠状动脉瘤治疗所面临的挑战。
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引用次数: 0
Regulating Personal Ultrasound Use Is Moot in 21st Century when Self-Identified Gender Will Be Self-Determined Way after Birth, Whereafter Future Procreation Will Be Further Self-Limited by Self-Determined Fertility 在 21 世纪,对个人超声波的使用进行监管是毫无意义的,因为自我性别鉴定将在出生后自行决定,此后的生育将进一步受到自我生育能力的限制。
IF 0.9 Q2 Medicine Pub Date : 2024-01-12 DOI: 10.4103/aca.aca_125_23
Deepak Gupta
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引用次数: 0
Thoracotomy Patients Under General Anesthesia: A Comparison on Intra-Operative Anesthetic and Analgesic Requirements, When Combined with Either Epidural Analgesia or Continuous Unilateral Paravertebral Analgesia 全身麻醉下的胸廓切开术患者:结合硬膜外镇痛或持续单侧椎旁镇痛时术中麻醉和镇痛需求的比较
IF 0.9 Q2 Medicine Pub Date : 2024-01-12 DOI: 10.4103/aca.aca_83_23
Saravana Babu, Muthu Kumar, S. Gadhinglajkar, D. M. Gregory, Neelam Aggarwal, Subin Sukesan
ABSTRACT Background and Objective: Regional analgesia is effective for post-thoracotomy pain. The primary objective of the study is to compare the intraoperative requirement of isoflurane and fentanyl between general anaesthesia (GA) with epidural analgesia and GA with paravertebral analgesia. Methods and Material: A prospective observational comparative study was conducted on 56 patients undergoing open thoracotomy procedures. The patients were divided into two groups of 28 by assigning the study participants alternatively to each group: Group GAE - received thoracic epidural catheterization with GA, and Group GAP - received ultrasound guided thoracic paravertebral catheterization on the operative side with GA. Intraoperative requirement of isoflurane, fentanyl, postoperative analgesia, stress response, need of rescue analgesics and adverse effects were observed and analysed. Results: 25 patients in each group were included in the data analysis. The intraoperative requirement of isoflurane (32.28 ± 1.88 vs 48.31 ± 4.34 ml; p < 0.0001) and fentanyl (128.87 ± 25.12 vs 157 ± 30.92 μg; p = 0.0009) were significantly less in the GAE group than in the GAP group. VAS scores and need of rescue analgesics and blood glucose levels were not statistically significant during the postoperative period (p > 0.05). The incidence of adverse effects was comparable except for hypotension and urinary retention which were significantly higher in the GAE group. Conclusion: GA with epidural analgesia resulted in significant reduction in the intraoperative consumption of isoflurane and fentanyl in comparison to GA with paravertebral analgesia. However, both the techniques were equally effective in the postoperative period.
摘要 背景与目的:区域镇痛对胸廓切开术后疼痛有效。本研究的主要目的是比较硬膜外镇痛全身麻醉(GA)和椎旁镇痛全身麻醉(GA)术中对异氟烷和芬太尼的需求量。方法和材料:对 56 名接受开胸手术的患者进行了前瞻性观察比较研究。将患者分为两组,每组 28 人:GAE组--使用GA进行胸腔硬膜外导管植入术,GAP组--使用GA在超声引导下在手术侧进行胸椎旁导管植入术。对术中异氟醚、芬太尼的需求量、术后镇痛、应激反应、镇痛药的需求量和不良反应进行了观察和分析。结果:数据分析包括每组 25 名患者。GAE 组术中所需的异氟醚(32.28 ± 1.88 vs 48.31 ± 4.34 ml;p < 0.0001)和芬太尼(128.87 ± 25.12 vs 157 ± 30.92 μg;p = 0.0009)明显少于 GAP 组。术后期间,VAS 评分、镇痛药和血糖水平均无统计学意义(p > 0.05)。除低血压和尿潴留在 GAE 组明显较高外,其他不良反应的发生率相当。结论与采用椎旁镇痛的 GA 相比,采用硬膜外镇痛的 GA 能显著减少术中异氟醚和芬太尼的用量。不过,这两种技术在术后同样有效。
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引用次数: 0
Inadvertent Puncture of Dilated Right Ventricle During Transversus Thoracic Muscle Plane Block: Lessons Learnt 横胸肌平面阻滞时不慎刺穿扩张的右心室:经验教训
IF 0.9 Q2 Medicine Pub Date : 2024-01-12 DOI: 10.4103/aca.aca_61_23
A.V. Varsha, S. Gadhinglajkar, Mamatha Munaf
ABSTRACT The transversus thoracic muscle plane (TTP) block is gaining widespread recognition in cardiac surgery, particularly in facilitating fast-tracking. Here, we report a case of inadvertent puncture of the right ventricle (RV) during the administration of ultra sound-guided (USG) TTP block in a 3-year-old child posted for atrial septal defect (ASD) closure and mitral valve repair. We also discuss the care that should be taken to avoid such complications and such cases require extra caution during TTP block.
摘要 经胸横肌平面(TTP)阻滞在心脏手术中得到广泛认可,尤其是在促进快速通道方面。在此,我们报告了一例因房间隔缺损(ASD)封堵术和二尖瓣修复术而接受超音波引导(USG)TTP阻滞治疗的 3 岁患儿在治疗过程中不慎穿刺右心室(RV)的病例。我们还讨论了为避免此类并发症而应采取的护理措施,以及在进行 TTP 阻滞时需要格外小心的病例。
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引用次数: 0
Retrospective Analysis of Hospital Acquired Infection and Antibiotic Resistance in Coronary Care Unit (CCU), Adult, and Pediatric Cardiology Wards 冠心病监护病房 (CCU)、成人和儿童心脏病病房医院获得性感染和抗生素耐药性的回顾性分析
IF 0.9 Q2 Medicine Pub Date : 2024-01-12 DOI: 10.4103/aca.aca_121_23
S. Yadav, Rajiv Narang, S. Mohapatra, A. Kapil, Bhawna Rao
ABSTRACT Background: Antibiotics resistance is an paramount threat affecting the whole world but nowhere situation is as gloomy as in India. No study till date regarding epidemiology of hospital acquired infections in coronary care units(CCU) and cardiology wards from India. From Indian perspective it is the first observational study to analyse microbiological profile and antibiotic resistance in CCU. The purpose of this observational study is to explore the epidemiology and importance of infections in CCU patients. Methodology: After ethics committee approval, the records of all patients who were admitted in coronary care units, adult and pediatric cardiology wards surgery between January 2020 and December 2021 were reviewed retrospectively. The type of organism,source of infection ,age wise distribution and seasonal variability among patients who developed hospital acquired infection (HAI) were determined. Results: 271 patients developed microbiologically documented HAI during from January 2020 to December 2021. Maximum number of organisms(78/271 28.78%) are isolated from urinary samples ,followed by blood stream(60/271 22.14%) and Endotracheal tube (54/271 19.92%). Acinetobacter baumanii (53/271, 19.5%) being the most common isolate among all the samples taken . Acinetobacter was the most frequent pathogens isolated in patients with LRTI and blood stream infection while E. coli was from urinary tract infection . In the adult population, infection with E. coli(24.6%) is the most common followed by Klebsiella pneumoniae (12.8%) and Acinetobacter baumanii (10.1%). In the pediatric population Acinetobacter baumanii (38.6%%) is the most common followed by Klebsiella pneumoniae (20.5%) and Methicillin Resistant Staphylococcus aureus, MRSA (6.8%). Commonly used antibiotics eg ciprofloxacin,ceftazidime and amikacin were found to be resistant against the top three isolates. Conclusion: Urinary tract was the most common site of infection and Gram-negative bacilli, the most common pathogens in adult as well as pediatric population. Antibiotic resistance was maximum with commonly isolated microorganisms.
ABSTRACT 背景:抗生素耐药性是影响全世界的最大威胁,但印度的情况却不容乐观。迄今为止,印度还没有关于冠心病监护病房(CCU)和心脏科病房医院感染流行病学的研究。从印度的角度来看,这是第一项分析冠心病监护病房微生物概况和抗生素耐药性的观察性研究。本观察性研究的目的是探讨 CCU 患者感染的流行病学和重要性。研究方法:经伦理委员会批准后,对 2020 年 1 月至 2021 年 12 月期间冠心病监护病房、成人和儿童心脏病病房外科收治的所有患者的病历进行回顾性审查。确定了医院感染(HAI)患者的微生物类型、感染源、年龄分布和季节变化。结果:在 2020 年 1 月至 2021 年 12 月期间,有 271 名患者发生了微生物记录的 HAI。从尿液样本中分离出的微生物数量最多(78/271,28.78%),其次是血流(60/271,22.14%)和气管插管(54/271,19.92%)。鲍曼不动杆菌(53/271,19.5%)是所有样本中最常见的分离菌。鲍曼不动杆菌是 LRTI 和血流感染患者最常分离到的病原体,而大肠杆菌则来自尿路感染。在成年人群中,感染大肠杆菌(24.6%)最为常见,其次是肺炎克雷伯菌(12.8%)和鲍曼不动杆菌(10.1%)。在儿科人群中,鲍曼不动杆菌(38.6%)最常见,其次是肺炎克雷伯菌(20.5%)和耐甲氧西林金黄色葡萄球菌(6.8%)。常用抗生素如环丙沙星、头孢他啶和阿米卡星对前三种分离菌株均有耐药性。结论泌尿道是最常见的感染部位,革兰氏阴性杆菌是成人和儿童中最常见的病原体。常见微生物对抗生素的耐药性最高。
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引用次数: 0
Sternal Wound Infection: A Surgeon’s Nemesis 胸骨伤口感染:外科医生的克星
IF 0.9 Q2 Medicine Pub Date : 2024-01-12 DOI: 10.4103/aca.aca_202_23
Alok K. Sharma
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引用次数: 0
期刊
Annals of Cardiac Anaesthesia
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