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Therapeutic drug monitoring. 治疗药物监测。
Pub Date : 1984-01-01

Therapeutic drug monitoring (TDM), a clinical laboratory technology that measures drug concentrations to regulate drug dosage, has become an important treatment aid in both inpatient and ambulatory care. TDM laboratory methods, including immunoassay (EIA, FIA, and RIA) and chromatographic techniques, are used to assay blood, urine, and saliva samples of patients taking therapeutic drugs; TDM is also useful in identifying abused drugs. This assessment describes specific drug assay techniques, their respective advantages and disadvantages, and costs. TDM's contribution to treatment outcomes, its impact on existing services, implications for laboratory personnel, and the extent of the TDM marketplace are discussed. Future techniques and TDM's contribution to reducing the length of patient stays are also reviewed.

治疗性药物监测(TDM)是一种通过测量药物浓度来调节药物剂量的临床实验室技术,已成为住院和门诊护理的重要治疗辅助手段。TDM实验室方法,包括免疫分析(EIA、FIA和RIA)和色谱技术,用于检测服用治疗药物患者的血液、尿液和唾液样本;TDM在识别滥用药物方面也很有用。本评估描述了具体的药物分析技术,它们各自的优点和缺点,以及成本。讨论了TDM对治疗结果的贡献、对现有服务的影响、对实验室人员的影响以及TDM市场的范围。未来的技术和TDM对减少患者住院时间的贡献也进行了回顾。
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引用次数: 0
Diffusion of new technologies: rational and irrational. 新技术的传播:理性与非理性。
Pub Date : 1984-01-01
S Perry

The diffusion of medical technology, the process by which new clinical procedures and devices come into use in the health care system, is an historical topic, as old as medicine itself. Hospitals, physicians, manufacturers, third-party payers, and patients all are factors in the demand for, and adoption and diffusion of, new medical technologies. The federal government also plays a role both in furthering technology diffusion through federally financed health programs and in attempting to control diffusion by stimulating state certificate of need and other regulatory programs. The history of the CT scanner's diffusion illustrates the problems that can result from the lack of a coherent strategy to control the diffusion of major medical technologies. Some of these same problems are now appearing in the diffusion of magnetic resonance imaging (MRI) devices. In the current health care environment, prospective payment and the continuing period of remarkable technological innovation are major influences on technology diffusion and on initiatives for technology assessment. The diffusion of technology can be made more rational by instituting a formal process to identify technologies (both old and new) that require assessment, by financial support for assessment efforts, by selective reimbursement for clinical trials, and by regionalization of costly procedures.

医疗技术的传播,即新的临床程序和设备在医疗保健系统中投入使用的过程,是一个与医学本身一样古老的历史话题。医院、医生、制造商、第三方支付方和患者都是影响新医疗技术需求、采用和传播的因素。联邦政府还通过联邦资助的健康项目来促进技术的传播,并试图通过刺激国家需求证明和其他监管项目来控制技术的传播。CT扫描仪的传播历史说明了由于缺乏连贯的策略来控制主要医疗技术的传播而导致的问题。一些同样的问题现在也出现在磁共振成像(MRI)设备的扩散上。在目前的卫生保健环境中,预期付款和持续的显著技术创新时期是技术扩散和技术评估举措的主要影响因素。通过建立一个正式的程序来确定需要评估的技术(旧的和新的),通过为评估工作提供财政支持,通过有选择地偿还临床试验费用,以及通过将昂贵的程序区域化,可以使技术的传播更加合理。
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引用次数: 0
The role of hospitals and physicians in technology diffusion. 医院和医生在技术传播中的作用。
Pub Date : 1984-01-01
F D Rollo

Hospitals and physicians play pivotal roles in the diffusion of health care technology because they, for the most part, are the owners and operators of medical equipment. At the same time, the way in which technology spreads through the health care community has an impact on the number of patients seen, and revenue earned, by hospitals and physicians. This synergistic relationship has been subjected to new forces with the ongoing development of new technologies and the reduction of insurers' generous cost reimbursements. "Competition" is the rallying cry about which much of this change has grown. Medicare's prospective payment system, federal and state cost-containment activities, and an increase in the number of alternative health care providers continue to incite competitive activities among hospitals and physicians as they vie for patients. To survive financially today, hospitals and physicians must have a clear understanding of the health care technology environment in which they function. Only then can a strategic plan be designed that identifies the tactics that would enable the hospital or physician not only to compete, but to succeed, in the battle to offer high-quality services that attract patients.

医院和医生在医疗保健技术的传播中发挥着关键作用,因为他们在很大程度上是医疗设备的所有者和经营者。与此同时,技术在医疗保健社区传播的方式对医院和医生看病的人数和收入产生了影响。随着新技术的不断发展和保险公司慷慨的费用报销的减少,这种协同关系受到了新的力量的影响。“竞争”是这场变革的战斗口号。联邦医疗保险的预期支付系统,联邦和州的成本控制活动,以及替代医疗服务提供者数量的增加,在医院和医生争夺病人的过程中,继续激起他们之间的竞争活动。为了在今天的经济环境中生存,医院和医生必须清楚地了解他们所处的医疗保健技术环境。只有这样,才能设计出战略计划,确定各种策略,使医院或医生在提供吸引患者的高质量服务的战斗中不仅能够竞争,而且能够取得成功。
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引用次数: 0
An ethical obligation to ensure access to new medical technologies? 确保获得新医疗技术的道德义务?
Pub Date : 1984-01-01
A M Capron

Because of health care's special status, society has an ethical obligation to ensure that all people have access to an adequate level of health care (including access to new technologies as well as existing ones), without facing excessive burdens in obtaining such care. Society's recognition and implementation of this obligation is all the more important because market forces, alone, will not produce appropriate distribution of health care resources. For those making decisions about resource allocation, ethical pitfalls can best be avoided if policy formulation is differentiated from clinical decisions about specific patients' access to care. The latter can and should be made by each patient's physician, but, to be effective, the former must be accomplished in broadly based political processes by both health care professionals and others. Further, decision making about access to new technologies should begin early in the research and development process, and should involve Medicare and other insurance carriers that will be called upon to pay for the technology. This course is highly preferable to waiting until the technology is ready for wide use--as is now common--and only then deciding whether to pay for it.

由于卫生保健的特殊地位,社会在道德上有义务确保所有人都能获得适当水平的卫生保健(包括获得新技术和现有技术),而不会在获得这种保健方面面临过重的负担。社会对这一义务的认识和执行更为重要,因为单靠市场力量不会产生保健资源的适当分配。对于那些做出资源分配决策的人来说,如果将政策制定与关于特定患者获得护理的临床决策区分开来,就可以最好地避免伦理陷阱。后者可以而且应该由每个病人的医生制定,但是,要想有效,前者必须由卫生保健专业人员和其他人在基础广泛的政治进程中完成。此外,关于获得新技术的决策应该在研发过程的早期就开始,并且应该让医疗保险和其他保险公司参与进来,因为它们将被要求为这项技术买单。这比等到技术准备好广泛应用——现在很普遍——然后再决定是否为它买单要好得多。
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引用次数: 0
A preliminary assessment. Digital imaging storage and retrieval in the 1980s. 初步评估。20世纪80年代的数字图像存储和检索。
Pub Date : 1984-01-01

The current status of digital imaging storage and retrieval is described, as applied to both digitally created images and those converted from conventional films. Technologies that are beginning to play a role in digital image management--particularly, different configurations of Picture Archiving and Communications Systems (PACS)--are examined in terms of their stage of development, equipment, and operating costs. This assessment finds that the future success and diffusion of these systems will depend upon the diagnostic adequacy of digital images, improvements in image digitizing processes, and the availability of optical disk or other low-cost mass storage. In addition, the paper concludes that Medicare's prospective payment system will greatly influence the spread of this technology because of both the cost-saving incentives the system will place on health care professionals and the still-undetermined method of capital cost reimbursement.

描述了数字图像存储和检索的现状,既适用于数字创建的图像,也适用于从传统胶片转换的图像。开始在数字图像管理中发挥作用的技术-特别是不同配置的图像存档和通信系统(PACS)-根据其开发阶段,设备和运营成本进行检查。这项评估发现,这些系统未来的成功和推广将取决于数字图像诊断的充分性、图像数字化过程的改进以及光盘或其他低成本大容量存储的可用性。此外,该论文得出结论,医疗保险的预期支付系统将极大地影响这项技术的传播,因为该系统将对医疗保健专业人员提供节省成本的激励,以及尚未确定的资本成本报销方法。
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引用次数: 0
Therapeutic drug monitoring. 治疗药物监测。
Pub Date : 1900-01-01 DOI: 10.1093/labmed/21.9.592
M. Oellerich
Therapeutic drug monitoring (TDM), a clinical laboratory technology that measures drug concentrations to regulate drug dosage, has become an important treatment aid in both inpatient and ambulatory care. TDM laboratory methods, including immunoassay (EIA, FIA, and RIA) and chromatographic techniques, are used to assay blood, urine, and saliva samples of patients taking therapeutic drugs; TDM is also useful in identifying abused drugs. This assessment describes specific drug assay techniques, their respective advantages and disadvantages, and costs. TDM's contribution to treatment outcomes, its impact on existing services, implications for laboratory personnel, and the extent of the TDM marketplace are discussed. Future techniques and TDM's contribution to reducing the length of patient stays are also reviewed.
治疗性药物监测(TDM)是一种通过测量药物浓度来调节药物剂量的临床实验室技术,已成为住院和门诊护理的重要治疗辅助手段。TDM实验室方法,包括免疫分析(EIA、FIA和RIA)和色谱技术,用于检测服用治疗药物患者的血液、尿液和唾液样本;TDM在识别滥用药物方面也很有用。本评估描述了具体的药物分析技术,它们各自的优点和缺点,以及成本。讨论了TDM对治疗结果的贡献、对现有服务的影响、对实验室人员的影响以及TDM市场的范围。未来的技术和TDM对减少患者住院时间的贡献也进行了回顾。
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引用次数: 1
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Journal of health care technology
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