Pub Date : 2004-01-10Epub Date: 2009-07-02DOI: 10.1002/scin.5591650213
J A N U A R Y 1 0 , 2 0 0 4 V O L . 1 6 5 2 9 report in the Dec. 6, 2003 Lancet. The response was best after the booster shot, but signs of immunity were already present 2 weeks after the first injection, Gambotto says. What’s more, when the scientists took blood from each monkey and exposed the sample to live SARS virus in a lab dish, the antibodies and T cells neutralized the virus. Gambotto and his colleagues now intend to test the vaccine in ferrets exposed to SARS virus. Ferrets are more susceptible to the disease than rhesus macaques are. Several groups are working on SARS vaccines. Gambotto predicts that one or more of these vaccines could reach large human trials within a year or two, especially if more outbreaks warrant an expedited approach. —N.S.
{"title":"Astronomy: X-ray images highlight galaxy collisions.","authors":"","doi":"10.1002/scin.5591650213","DOIUrl":"https://doi.org/10.1002/scin.5591650213","url":null,"abstract":"J A N U A R Y 1 0 , 2 0 0 4 V O L . 1 6 5 2 9 report in the Dec. 6, 2003 Lancet. The response was best after the booster shot, but signs of immunity were already present 2 weeks after the first injection, Gambotto says. What’s more, when the scientists took blood from each monkey and exposed the sample to live SARS virus in a lab dish, the antibodies and T cells neutralized the virus. Gambotto and his colleagues now intend to test the vaccine in ferrets exposed to SARS virus. Ferrets are more susceptible to the disease than rhesus macaques are. Several groups are working on SARS vaccines. Gambotto predicts that one or more of these vaccines could reach large human trials within a year or two, especially if more outbreaks warrant an expedited approach. —N.S.","PeriodicalId":80166,"journal":{"name":"Science news","volume":"165 2","pages":"29"},"PeriodicalIF":0.0,"publicationDate":"2004-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/scin.5591650213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37866516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-01-10Epub Date: 2009-07-02DOI: 10.1002/scin.5591650211
{"title":"Biology: Brain gene is tied to obesity.","authors":"","doi":"10.1002/scin.5591650211","DOIUrl":"https://doi.org/10.1002/scin.5591650211","url":null,"abstract":"","PeriodicalId":80166,"journal":{"name":"Science news","volume":"165 2","pages":"28"},"PeriodicalIF":0.0,"publicationDate":"2004-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/scin.5591650211","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37854869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2004-01-10Epub Date: 2009-07-02DOI: 10.1002/scin.5591650214
J A N U A R Y 1 0 , 2 0 0 4 V O L . 1 6 5 2 9 report in the Dec. 6, 2003 Lancet. The response was best after the booster shot, but signs of immunity were already present 2 weeks after the first injection, Gambotto says. What’s more, when the scientists took blood from each monkey and exposed the sample to live SARS virus in a lab dish, the antibodies and T cells neutralized the virus. Gambotto and his colleagues now intend to test the vaccine in ferrets exposed to SARS virus. Ferrets are more susceptible to the disease than rhesus macaques are. Several groups are working on SARS vaccines. Gambotto predicts that one or more of these vaccines could reach large human trials within a year or two, especially if more outbreaks warrant an expedited approach. —N.S.
{"title":"Environment: When testosterone gets down and dirty.","authors":"","doi":"10.1002/scin.5591650214","DOIUrl":"https://doi.org/10.1002/scin.5591650214","url":null,"abstract":"J A N U A R Y 1 0 , 2 0 0 4 V O L . 1 6 5 2 9 report in the Dec. 6, 2003 Lancet. The response was best after the booster shot, but signs of immunity were already present 2 weeks after the first injection, Gambotto says. What’s more, when the scientists took blood from each monkey and exposed the sample to live SARS virus in a lab dish, the antibodies and T cells neutralized the virus. Gambotto and his colleagues now intend to test the vaccine in ferrets exposed to SARS virus. Ferrets are more susceptible to the disease than rhesus macaques are. Several groups are working on SARS vaccines. Gambotto predicts that one or more of these vaccines could reach large human trials within a year or two, especially if more outbreaks warrant an expedited approach. —N.S.","PeriodicalId":80166,"journal":{"name":"Science news","volume":"165 2","pages":"29"},"PeriodicalIF":0.0,"publicationDate":"2004-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/scin.5591650214","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37866515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2003-11-29Epub Date: 2009-07-02DOI: 10.2307/4018991
John Travis
N O V E M B E R 2 9 , 2 0 0 3 V O L . 1 6 4 3 4 1 S. D A V IS /P N A S Martin A.J. Williams, a geographer at Australia’s University of Adelaide. West of these contours, the terrain slopes gently toward the river, dropping about 15 centimeters across each westward kilometer. East of the features, the ground rises at a steeper gradient of 3 meters per kilometer. The consistent level of the features, like that of a gargantuan bathtub ring, marks the wave-scoured shoreline of an ancient lake, says Williams. North of Esh Shawal, traces of the lake’s eastern shoreline become vague, because sediments dumped there by the Blue Nile have covered the area. However, signs of erosion along the opposite shore can be found more than 200 km north of the town. Neither the satellite images nor previous surveys provide any clue about where the ancient lake’s southern shore may have been located. Williams and his colleagues describe their findings in the November Geology. Because the southeastern shoreline is well defined, the arc-shaped features probably took a long time to form, says Michael R. Talbot, a geologist at the University of Bergen in Norway. The apparent absence of multiple shorelines at various elevations along the river valley indicates the lake was a permanent and stable feature, not one that rose and fell with the seasons and reached different levels each year. The White Nile’s ancient lake couldn’t exist today because the river doesn’t carry enough water to keep up with evaporation over a lake-size area. At some sites in the region, reservoirs can lose as much as 1 cm of water per day, says Williams. Analyses of clay-rich sediments excavated from a trench near Esh Shawal suggest that layers now 5 m below ground level were deposited on the lake bottom more than 250,000 years ago. Williams and his colleagues suggest that the lake formed and existed between 420,000 and 360,000 years ago, during a wetter-than-normal period between ice ages. —S. PERKINS
{"title":"Protein portal: Enzyme acts as door for the sars virus.","authors":"John Travis","doi":"10.2307/4018991","DOIUrl":"https://doi.org/10.2307/4018991","url":null,"abstract":"N O V E M B E R 2 9 , 2 0 0 3 V O L . 1 6 4 3 4 1 S. D A V IS /P N A S Martin A.J. Williams, a geographer at Australia’s University of Adelaide. West of these contours, the terrain slopes gently toward the river, dropping about 15 centimeters across each westward kilometer. East of the features, the ground rises at a steeper gradient of 3 meters per kilometer. The consistent level of the features, like that of a gargantuan bathtub ring, marks the wave-scoured shoreline of an ancient lake, says Williams. North of Esh Shawal, traces of the lake’s eastern shoreline become vague, because sediments dumped there by the Blue Nile have covered the area. However, signs of erosion along the opposite shore can be found more than 200 km north of the town. Neither the satellite images nor previous surveys provide any clue about where the ancient lake’s southern shore may have been located. Williams and his colleagues describe their findings in the November Geology. Because the southeastern shoreline is well defined, the arc-shaped features probably took a long time to form, says Michael R. Talbot, a geologist at the University of Bergen in Norway. The apparent absence of multiple shorelines at various elevations along the river valley indicates the lake was a permanent and stable feature, not one that rose and fell with the seasons and reached different levels each year. The White Nile’s ancient lake couldn’t exist today because the river doesn’t carry enough water to keep up with evaporation over a lake-size area. At some sites in the region, reservoirs can lose as much as 1 cm of water per day, says Williams. Analyses of clay-rich sediments excavated from a trench near Esh Shawal suggest that layers now 5 m below ground level were deposited on the lake bottom more than 250,000 years ago. Williams and his colleagues suggest that the lake formed and existed between 420,000 and 360,000 years ago, during a wetter-than-normal period between ice ages. —S. PERKINS","PeriodicalId":80166,"journal":{"name":"Science news","volume":"164 22","pages":"341-342"},"PeriodicalIF":0.0,"publicationDate":"2003-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2307/4018991","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37866507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2003-11-29Epub Date: 2009-07-02DOI: 10.2307/4018992
Peter Weiss
{"title":"Electronic thread: Fiber transistor may lead to woven circuits.","authors":"Peter Weiss","doi":"10.2307/4018992","DOIUrl":"https://doi.org/10.2307/4018992","url":null,"abstract":"","PeriodicalId":80166,"journal":{"name":"Science news","volume":"164 22","pages":"342"},"PeriodicalIF":0.0,"publicationDate":"2003-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2307/4018992","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37866508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2003-11-29Epub Date: 2009-07-02DOI: 10.1002/scin.5591642205
Sid Perkins
{"title":"Lake retreat: African river valley once hosted big lake.","authors":"Sid Perkins","doi":"10.1002/scin.5591642205","DOIUrl":"https://doi.org/10.1002/scin.5591642205","url":null,"abstract":"","PeriodicalId":80166,"journal":{"name":"Science news","volume":"164 22","pages":"340-341"},"PeriodicalIF":0.0,"publicationDate":"2003-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/scin.5591642205","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37866614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2003-11-29Epub Date: 2009-07-02DOI: 10.2307/4018993
Ben Harder
3 4 2 N O V E M B E R 2 9 , 2 0 0 3 V O L . 1 6 4 Md. “It’s absolutely amazing how quickly they did this.” Until now, ACE2 has largely interested cardiologists. Several decades ago, physicians began using inhibitors of a similar enzyme, ACE, to treat high blood pressure and heart disease. A few years ago, scientists discovered ACE2 and began to look for compounds that block its activities. There’s a good correspondence between tissues that make ACE2—the heart, lungs, and kidneys, for example—and ones affected by the SARS virus, notes Farzan. He and his colleagues are now looking into whether known ACE2 inhibitors block the SARS virus from cells. It’s possible that these inhibitors may thwart ACE2’s function but still allow the virus to grab onto the enzyme, cautions Farzan. Gary Nabel, director of the National Institutes of Health Vaccine Research Center in Bethesda, Md., calls the new work a “fascinating discovery” but notes that the SARS virus may exploit proteins other than ACE2 as receptors. —J. TRAVIS
{"title":"The next MTBE: Contamination from fuel additives could spread.","authors":"Ben Harder","doi":"10.2307/4018993","DOIUrl":"https://doi.org/10.2307/4018993","url":null,"abstract":"3 4 2 N O V E M B E R 2 9 , 2 0 0 3 V O L . 1 6 4 Md. “It’s absolutely amazing how quickly they did this.” Until now, ACE2 has largely interested cardiologists. Several decades ago, physicians began using inhibitors of a similar enzyme, ACE, to treat high blood pressure and heart disease. A few years ago, scientists discovered ACE2 and began to look for compounds that block its activities. There’s a good correspondence between tissues that make ACE2—the heart, lungs, and kidneys, for example—and ones affected by the SARS virus, notes Farzan. He and his colleagues are now looking into whether known ACE2 inhibitors block the SARS virus from cells. It’s possible that these inhibitors may thwart ACE2’s function but still allow the virus to grab onto the enzyme, cautions Farzan. Gary Nabel, director of the National Institutes of Health Vaccine Research Center in Bethesda, Md., calls the new work a “fascinating discovery” but notes that the SARS virus may exploit proteins other than ACE2 as receptors. —J. TRAVIS","PeriodicalId":80166,"journal":{"name":"Science news","volume":"164 22","pages":"342"},"PeriodicalIF":0.0,"publicationDate":"2003-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2307/4018993","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37866510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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