首页 > 最新文献

Annals of Surgical Treatment and Research最新文献

英文 中文
Addressing the challenges of missed parathyroid glands in ultrasonography for secondary hyperparathyroidism: a retrospective observational study. 应对继发性甲状旁腺功能亢进症超声造影漏检甲状旁腺的挑战:一项回顾性观察研究。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-08-26 DOI: 10.4174/astr.2024.107.3.136
Shen-En Chou,Cheng-Hsi Yeh,Shun-Yu Chi,Fong-Fu Chou,Yi-Ju Wu,Yen-Hsiang Chang,Yi-Chia Chan
PurposePreoperative localization plays an important role in secondary hyperparathyroidism (SHPT) surgery. The advantages of neck ultrasound (US) include high availability and low cost. However, the reported sensitivity of US is 54%-76%, and the reason for missed parathyroid glands (PGs) on US has been rarely addressed.MethodsFifty-four patients who were diagnosed with renal SHPT from September 2020 to March 2022 were included in this retrospective study. Preoperative localization included surgeon-oriented US and technetium 99m-sestamibi single-photon emission CT (SPECT)/CT.ResultsA total of 212 PGs were pathologically confirmed, resulting in a success rate of 96.2% (52 of 54). Using echo, 193 PGs (91.0%) were accurately localized, while 19 glands (9.0%) were not identified, including those in ectopic positions (n = 12, at thymus or intrathyroid or others), of small size (<1 cm, n = 6), or overlapping with an ipsilateral PG (n = 1). US accurately detected 4 PGs in 36 (66.7%) patients, while SPECT/CT localized 4 glands in 19 patients (35.2%). Although the number of US-detectable PGs was not associated with success rate, it showed a significant negative correlation with surgical time (rs = -0.459, P = 0.002).ConclusionUS detected 4 glands in 66% of SHPT patients with a sensitivity of 90% for localization. Ectopic position and small size were the most common reasons for the failure to detect PG on US. Complete preoperative echo localization might shorten operating time.
目的 术前定位在继发性甲状旁腺功能亢进症(SHPT)手术中起着重要作用。颈部超声波(US)的优点是可用性高、成本低。方法这项回顾性研究纳入了2020年9月至2022年3月期间确诊为肾性SHPT的54例患者。结果共有 212 个 PG 得到病理证实,成功率为 96.2%(54 例中有 52 例)。通过回波检查,193 个 PG(91.0%)被准确定位,19 个腺体(9.0%)未被识别,其中包括异位腺体(12 个,位于胸腺或甲状腺内或其他部位)、小腺体(<1 厘米,6 个)或与同侧 PG 重叠的腺体(1 个)。36 名患者(66.7%)通过 US 准确检测到 4 个 PG,而 19 名患者(35.2%)通过 SPECT/CT 定位到 4 个腺体。虽然 US 检测到的 PG 数量与成功率无关,但与手术时间呈显著负相关(rs = -0.459,P = 0.002)。异位和体积小是 US 未检测到 PG 的最常见原因。术前完整的回声定位可缩短手术时间。
{"title":"Addressing the challenges of missed parathyroid glands in ultrasonography for secondary hyperparathyroidism: a retrospective observational study.","authors":"Shen-En Chou,Cheng-Hsi Yeh,Shun-Yu Chi,Fong-Fu Chou,Yi-Ju Wu,Yen-Hsiang Chang,Yi-Chia Chan","doi":"10.4174/astr.2024.107.3.136","DOIUrl":"https://doi.org/10.4174/astr.2024.107.3.136","url":null,"abstract":"PurposePreoperative localization plays an important role in secondary hyperparathyroidism (SHPT) surgery. The advantages of neck ultrasound (US) include high availability and low cost. However, the reported sensitivity of US is 54%-76%, and the reason for missed parathyroid glands (PGs) on US has been rarely addressed.MethodsFifty-four patients who were diagnosed with renal SHPT from September 2020 to March 2022 were included in this retrospective study. Preoperative localization included surgeon-oriented US and technetium 99m-sestamibi single-photon emission CT (SPECT)/CT.ResultsA total of 212 PGs were pathologically confirmed, resulting in a success rate of 96.2% (52 of 54). Using echo, 193 PGs (91.0%) were accurately localized, while 19 glands (9.0%) were not identified, including those in ectopic positions (n = 12, at thymus or intrathyroid or others), of small size (<1 cm, n = 6), or overlapping with an ipsilateral PG (n = 1). US accurately detected 4 PGs in 36 (66.7%) patients, while SPECT/CT localized 4 glands in 19 patients (35.2%). Although the number of US-detectable PGs was not associated with success rate, it showed a significant negative correlation with surgical time (rs = -0.459, P = 0.002).ConclusionUS detected 4 glands in 66% of SHPT patients with a sensitivity of 90% for localization. Ectopic position and small size were the most common reasons for the failure to detect PG on US. Complete preoperative echo localization might shorten operating time.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142269915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The clinical effect of endoscopic and open surgery in the treatment of thyroid cancer and their effect on the blood coagulation state: a comparative study. 内窥镜手术和开放手术治疗甲状腺癌的临床效果及其对血液凝固状态的影响:一项比较研究。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-08-26 DOI: 10.4174/astr.2024.107.3.127
Qiyin Xu,Li Zhu,Weiping Chen,Weibin Peng
PurposeThis study was performed to compare the therapeutic efficacy of endoscopic surgery and open surgery and their effects on postoperative blood coagulation state in patients with thyroid cancer, and to provide evidence for the prevention measurement of thrombosis in the perioperative period.MethodsOne hundred patients with thyroid cancer who received treatment in our hospital from January 2021 to December 2021, were randomly divided into an endoscopic group and an open surgery group, with 50 patients in each group. The patients in the open surgery group were treated by traditional open surgery, while patients in the endoscopic group accepted endoscopic surgery. The clinically therapeutic effect and blood coagulation of the 2 groups were compared.ResultsIntraoperative blood loss and length of hospital stay were lower, and operative time was longer in the endoscopic group than in the open surgery group (P < 0.05). The 24-hour postoperative fibrinogen and D-dimer levels were higher in both groups than in the preoperative period, while PT was shorter (P < 0.05). There were no significant differences in postoperative complications and follow-up between the 2 groups (P > 0.05), but the incidence of complications, postoperative metastases, and thrombosis was relatively low in the endoscopic group.ConclusionIn the treatment of patients with thyroid cancer, endoscopic surgery has the advantages of less blood loss, fewer complications, and so on. Endoscopic and open surgery can lead to a hypercoagulable state, but the effect of endoscopic surgery is better than that of open surgery.
摘要] 目的 比较内镜手术与开放手术对甲状腺癌患者术后血凝状态的疗效及影响,为围手术期血栓的预防测量提供依据。开放手术组患者接受传统开放手术治疗,内镜组患者接受内镜手术治疗。结果内镜组患者的术中失血量和住院时间低于开放手术组,手术时间长于开放手术组(P < 0.05)。两组术后 24 小时纤维蛋白原和 D-二聚体水平均高于术前,而 PT 缩短(P < 0.05)。两组患者术后并发症和随访无明显差异(P>0.05),但内镜组并发症、术后转移和血栓形成的发生率相对较低。内镜手术和开放手术均可导致高凝状态,但内镜手术的效果优于开放手术。
{"title":"The clinical effect of endoscopic and open surgery in the treatment of thyroid cancer and their effect on the blood coagulation state: a comparative study.","authors":"Qiyin Xu,Li Zhu,Weiping Chen,Weibin Peng","doi":"10.4174/astr.2024.107.3.127","DOIUrl":"https://doi.org/10.4174/astr.2024.107.3.127","url":null,"abstract":"PurposeThis study was performed to compare the therapeutic efficacy of endoscopic surgery and open surgery and their effects on postoperative blood coagulation state in patients with thyroid cancer, and to provide evidence for the prevention measurement of thrombosis in the perioperative period.MethodsOne hundred patients with thyroid cancer who received treatment in our hospital from January 2021 to December 2021, were randomly divided into an endoscopic group and an open surgery group, with 50 patients in each group. The patients in the open surgery group were treated by traditional open surgery, while patients in the endoscopic group accepted endoscopic surgery. The clinically therapeutic effect and blood coagulation of the 2 groups were compared.ResultsIntraoperative blood loss and length of hospital stay were lower, and operative time was longer in the endoscopic group than in the open surgery group (P < 0.05). The 24-hour postoperative fibrinogen and D-dimer levels were higher in both groups than in the preoperative period, while PT was shorter (P < 0.05). There were no significant differences in postoperative complications and follow-up between the 2 groups (P > 0.05), but the incidence of complications, postoperative metastases, and thrombosis was relatively low in the endoscopic group.ConclusionIn the treatment of patients with thyroid cancer, endoscopic surgery has the advantages of less blood loss, fewer complications, and so on. Endoscopic and open surgery can lead to a hypercoagulable state, but the effect of endoscopic surgery is better than that of open surgery.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142264711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effective utilization of polypectomy in endoscopic salvage treatment of rectal neuroendocrine tumors: a retrospective cohort study. 在直肠神经内分泌肿瘤的内镜挽救治疗中有效利用息肉切除术:一项回顾性队列研究。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-08-26 DOI: 10.4174/astr.2024.107.3.151
Yeonuk Ju,Jun Woo Bong,Chinock Cheong,Sanghee Kang,Byung Wook Min,Sun Il Lee
PurposeCurrent guidelines recommend endoscopic resection for rectal neuroendocrine tumors (RNETs) under 10 mm. Incomplete resections necessitate salvage procedures, highlighting the need for complete R0 resection. This study evaluates the efficacy and safety of wide hot snare polypectomy (WHSP) compared to endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) for the salvage treatment of small RNETs.MethodsThis retrospective study was conducted at Korea University Guro Hospital from January 2018 to December 2022. It compared the outcomes of salvage resections for RNETs ≤10 mm using 2 approaches: ESD and EMR vs. WHSP. Demographics, tumor characteristics, and clinical outcomes were compared. Efficacy was evaluated by the histological complete resection rate and procedure time, while safety was assessed by the incidence of complications.ResultsOut of 135 patients undergoing salvage resection for RNET, 14 who underwent transanal excision were excluded. Of the remaining 121, 99 underwent EMR or ESD, and 22 underwent WHSP. Baseline characteristics were similar between the 2 groups. The WHSP group demonstrated a significantly higher R0 resection rate (72.7% vs. 49.5%, P = 0.010) and a shorter median procedure time (3.5 minutes vs. 8.3 minutes). No complications were reported in the WHSP group.ConclusionWHSP is a rapid, straightforward, safe, and effective approach for the salvage treatment of RNETs less than 10 mm in diameter, particularly in patients without additional risk factors.
目的现行指南建议对10毫米以下的直肠神经内分泌肿瘤(RNET)进行内窥镜切除。如果切除不彻底,就必须进行挽救手术,这凸显了完全R0切除的必要性。本研究评估了宽热网膜息肉切除术(WHSP)与内镜下粘膜下剥离术(ESD)和内镜下粘膜切除术(EMR)相比,对小型RNETs进行挽救性治疗的有效性和安全性。方法这项回顾性研究于2018年1月至2022年12月在韩国大学九老医院进行。该研究比较了使用两种方法对≤10毫米的RNET进行挽救性切除的结果:ESD和EMR vs. WHSP。比较了人口统计学、肿瘤特征和临床结果。根据组织学完全切除率和手术时间评估疗效,根据并发症发生率评估安全性。其余121人中,99人接受了EMR或ESD,22人接受了WHSP。两组患者的基线特征相似。WHSP 组的 R0 切除率明显更高(72.7% 对 49.5%,P = 0.010),中位手术时间更短(3.5 分钟对 8.3 分钟)。结论WHSP是挽救治疗直径小于10毫米的RNET的一种快速、直接、安全和有效的方法,尤其适用于无其他风险因素的患者。
{"title":"Effective utilization of polypectomy in endoscopic salvage treatment of rectal neuroendocrine tumors: a retrospective cohort study.","authors":"Yeonuk Ju,Jun Woo Bong,Chinock Cheong,Sanghee Kang,Byung Wook Min,Sun Il Lee","doi":"10.4174/astr.2024.107.3.151","DOIUrl":"https://doi.org/10.4174/astr.2024.107.3.151","url":null,"abstract":"PurposeCurrent guidelines recommend endoscopic resection for rectal neuroendocrine tumors (RNETs) under 10 mm. Incomplete resections necessitate salvage procedures, highlighting the need for complete R0 resection. This study evaluates the efficacy and safety of wide hot snare polypectomy (WHSP) compared to endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) for the salvage treatment of small RNETs.MethodsThis retrospective study was conducted at Korea University Guro Hospital from January 2018 to December 2022. It compared the outcomes of salvage resections for RNETs ≤10 mm using 2 approaches: ESD and EMR vs. WHSP. Demographics, tumor characteristics, and clinical outcomes were compared. Efficacy was evaluated by the histological complete resection rate and procedure time, while safety was assessed by the incidence of complications.ResultsOut of 135 patients undergoing salvage resection for RNET, 14 who underwent transanal excision were excluded. Of the remaining 121, 99 underwent EMR or ESD, and 22 underwent WHSP. Baseline characteristics were similar between the 2 groups. The WHSP group demonstrated a significantly higher R0 resection rate (72.7% vs. 49.5%, P = 0.010) and a shorter median procedure time (3.5 minutes vs. 8.3 minutes). No complications were reported in the WHSP group.ConclusionWHSP is a rapid, straightforward, safe, and effective approach for the salvage treatment of RNETs less than 10 mm in diameter, particularly in patients without additional risk factors.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142264714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive factors for postoperative ileus after elective right hemicolectomy performed on over 80% Enhanced Recovery After Surgery-adherent patients: a retrospective cohort study. 一项回顾性队列研究:对 80% 以上坚持 "术后加强康复 "的患者实施择期右半结肠切除术后出现术后回肠梗阻的预测因素。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-08-26 DOI: 10.4174/astr.2024.107.3.158
Mohamud Aden,Tom Scheinin,Shamel Ismail,Antti J Kivelä,Suvi Rasilainen
PurposeLaparoscopic right hemicolectomy is the standard surgical approach for treatment of right-sided colonic neoplasms. Although performed within a strict Enhanced Recovery After Surgery (ERAS) program, patients still develop postoperative ileus. The aim of this study was to describe the factors responsible for postoperative ileus after right hemicolectomy in a patient population with over 80% ERAS adherence.MethodsIn this retrospective study, we analyzed 499 consecutive patients undergoing elective right-sided colectomy for neoplastic disease in a single high-volume center. All patients followed an updated ERAS program.ResultsThe overall median ERAS adherence was 80%. Patients with ≥ 80% adherence (n = 271) were included in further analysis. Their median ERAS adherence was 88.9% (interquartile range, 80-90; range, 80-100). Twenty-four of 271 patients (8.9%) developed postoperative ileus. A univariate regression analysis revealed carcinoma situated in the transverse colon, duration of operation over 200 minutes, and opiate consumption over 10 mg on the second postoperative day (POD) to be associated with a significantly higher risk of postoperative ileus. Multivariate regression analysis revealed that duration of surgery over 200 minutes (odds ratio [OR], 2.4; 95% confidence interval [CI], 1.0-5.8; P = 0.045) and opiate consumption over 10 mg on POD 2 (OR, 4.8; 95% CI, 1.6-14.3; P = 0.005) independently predict a higher risk for postoperative ileus. The median length of hospital stay was significantly longer in patients with postoperative ileus (8 days vs. 3 days, P < 0.001). None of the 271 patients died during a 30-day follow-up.ConclusionLong duration of surgery, even minor postoperative opiate use, predict a higher risk for postoperative ileus in strictly ERAS-adherent patients undergoing laparoscopic right hemicolectomy.
目的腹腔镜右半结肠切除术是治疗右侧结肠肿瘤的标准手术方法。尽管手术是在严格的术后恢复(ERAS)计划下进行的,但患者仍会出现术后回肠梗阻。本研究的目的是描述在ERAS遵守率超过80%的患者群体中,导致右半结肠切除术后回肠淤血的因素。方法在这项回顾性研究中,我们分析了在一个高产量中心接受肿瘤性疾病右侧结肠切除术的499名连续患者。所有患者都遵守了最新的ERAS计划。结果ERAS遵守率的总体中位数为80%。坚持率≥80%的患者(n = 271)被纳入进一步分析。他们的ERAS坚持率中位数为88.9%(四分位间范围为80-90;范围为80-100)。271 例患者中有 24 例(8.9%)出现术后回肠梗阻。单变量回归分析表明,横结肠癌、手术时间超过 200 分钟以及术后第二天(POD)服用阿片类药物超过 10 毫克与术后回肠梗阻的风险显著增加有关。多变量回归分析表明,手术时间超过 200 分钟(几率比 [OR],2.4;95% 置信区间 [CI],1.0-5.8;P = 0.045)和术后第 2 天服用阿片类药物超过 10 毫克(OR,4.8;95% 置信区间 [CI],1.6-14.3;P = 0.005)可独立预测较高的术后回肠梗阻风险。术后回肠梗阻患者的中位住院时间明显更长(8 天 vs. 3 天,P < 0.001)。结论在严格遵守ERAS的腹腔镜右半结肠切除术患者中,手术时间长,甚至术后轻微使用阿片类药物都会增加术后回肠梗阻的风险。
{"title":"Predictive factors for postoperative ileus after elective right hemicolectomy performed on over 80% Enhanced Recovery After Surgery-adherent patients: a retrospective cohort study.","authors":"Mohamud Aden,Tom Scheinin,Shamel Ismail,Antti J Kivelä,Suvi Rasilainen","doi":"10.4174/astr.2024.107.3.158","DOIUrl":"https://doi.org/10.4174/astr.2024.107.3.158","url":null,"abstract":"PurposeLaparoscopic right hemicolectomy is the standard surgical approach for treatment of right-sided colonic neoplasms. Although performed within a strict Enhanced Recovery After Surgery (ERAS) program, patients still develop postoperative ileus. The aim of this study was to describe the factors responsible for postoperative ileus after right hemicolectomy in a patient population with over 80% ERAS adherence.MethodsIn this retrospective study, we analyzed 499 consecutive patients undergoing elective right-sided colectomy for neoplastic disease in a single high-volume center. All patients followed an updated ERAS program.ResultsThe overall median ERAS adherence was 80%. Patients with ≥ 80% adherence (n = 271) were included in further analysis. Their median ERAS adherence was 88.9% (interquartile range, 80-90; range, 80-100). Twenty-four of 271 patients (8.9%) developed postoperative ileus. A univariate regression analysis revealed carcinoma situated in the transverse colon, duration of operation over 200 minutes, and opiate consumption over 10 mg on the second postoperative day (POD) to be associated with a significantly higher risk of postoperative ileus. Multivariate regression analysis revealed that duration of surgery over 200 minutes (odds ratio [OR], 2.4; 95% confidence interval [CI], 1.0-5.8; P = 0.045) and opiate consumption over 10 mg on POD 2 (OR, 4.8; 95% CI, 1.6-14.3; P = 0.005) independently predict a higher risk for postoperative ileus. The median length of hospital stay was significantly longer in patients with postoperative ileus (8 days vs. 3 days, P < 0.001). None of the 271 patients died during a 30-day follow-up.ConclusionLong duration of surgery, even minor postoperative opiate use, predict a higher risk for postoperative ileus in strictly ERAS-adherent patients undergoing laparoscopic right hemicolectomy.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142269470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical significance and outcomes of adult living donor liver transplantation for acute liver failure: a retrospective cohort study based on 15-year single-center experience. 成人活体肝移植治疗急性肝功能衰竭的临床意义和疗效:基于 15 年单中心经验的回顾性队列研究。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-08-26 DOI: 10.4174/astr.2024.107.3.167
Geun-Hyeok Yang,Young-In Yoon,Shin Hwang,Ki-Hun Kim,Chul-Soo Ahn,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Gil-Chun Park,Sung-Gyu Lee
PurposeThis study aimed to describe adult living donor liver transplantation (LDLT) for acute liver failure and evaluate its clinical significance by comparing its surgical and survival outcomes with those of deceased donor liver transplantation (DDLT).MethodsWe retrospectively reviewed the medical records of 267 consecutive patients (161 LDLT recipients and 106 DDLT recipients) aged 18 years or older who underwent liver transplantation between January 2006 and December 2020.ResultsThe mean periods from hepatic encephalopathy to liver transplantation were 5.85 days and 8.35 days for LDLT and DDLT, respectively (P = 0.091). Among these patients, 121 (45.3%) had grade III or IV hepatic encephalopathy (living, 34.8% vs. deceased, 61.3%; P < 0.001), and 38 (14.2%) had brain edema (living, 16.1% vs. deceased, 11.3%; P = 0.269) before liver transplantation. There were no significant differences in in-hospital mortality (living, 11.8% vs. deceased, 15.1%; P = 0.435), 10-year overall survival (living, 90.8% vs. deceased, 84.0%; P = 0.096), and graft survival (living, 83.5% vs. deceased, 71.3%; P = 0.051). However, postoperatively, the mean intensive care unit stay was shorter in the LDLT group (5.0 days vs. 9.5 days, P < 0.001). In-hospital mortality was associated with vasopressor use (odds ratio [OR], 3.40; 95% confidence interval [CI], 1.45-7.96; P = 0.005) and brain edema (OR, 2.75; 95% CI, 1.16-6.52; P = 0.022) of recipient at the time of transplantation. However, LDLT (OR, 1.26; 95% CI, 0.59-2.66; P = 0.553) was not independently associated with in-hospital mortality.ConclusionLDLT is feasible for acute liver failure when organs from deceased donors are not available.
目的本研究旨在描述成人活体肝移植(LDLT)治疗急性肝功能衰竭的情况,并通过比较其与死亡供体肝移植(DDLT)的手术和存活结果来评估其临床意义。方法我们回顾性地查看了2006年1月至2020年12月期间接受肝移植手术的267名年龄在18岁或18岁以上的连续患者(161名LDLT受者和106名DDLT受者)的病历。在这些患者中,有121人(45.3%)在肝移植前出现了III级或IV级肝性脑病(生者34.8%,死者61.3%;P < 0.001),38人(14.2%)出现了脑水肿(生者16.1%,死者11.3%;P = 0.269)。院内死亡率(活体,11.8%;死亡,15.1%;P = 0.435)、10年总存活率(活体,90.8%;死亡,84.0%;P = 0.096)和移植物存活率(活体,83.5%;死亡,71.3%;P = 0.051)均无明显差异。不过,术后 LDLT 组的重症监护室平均住院时间较短(5.0 天 vs. 9.5 天,P < 0.001)。院内死亡率与移植时受者使用血管加压药(几率比 [OR],3.40;95% 置信区间 [CI],1.45-7.96;P = 0.005)和脑水肿(OR,2.75;95% CI,1.16-6.52;P = 0.022)有关。然而,LDLT(OR,1.26;95% CI,0.59-2.66;P = 0.553)与院内死亡率无独立关联。
{"title":"Clinical significance and outcomes of adult living donor liver transplantation for acute liver failure: a retrospective cohort study based on 15-year single-center experience.","authors":"Geun-Hyeok Yang,Young-In Yoon,Shin Hwang,Ki-Hun Kim,Chul-Soo Ahn,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Gil-Chun Park,Sung-Gyu Lee","doi":"10.4174/astr.2024.107.3.167","DOIUrl":"https://doi.org/10.4174/astr.2024.107.3.167","url":null,"abstract":"PurposeThis study aimed to describe adult living donor liver transplantation (LDLT) for acute liver failure and evaluate its clinical significance by comparing its surgical and survival outcomes with those of deceased donor liver transplantation (DDLT).MethodsWe retrospectively reviewed the medical records of 267 consecutive patients (161 LDLT recipients and 106 DDLT recipients) aged 18 years or older who underwent liver transplantation between January 2006 and December 2020.ResultsThe mean periods from hepatic encephalopathy to liver transplantation were 5.85 days and 8.35 days for LDLT and DDLT, respectively (P = 0.091). Among these patients, 121 (45.3%) had grade III or IV hepatic encephalopathy (living, 34.8% vs. deceased, 61.3%; P < 0.001), and 38 (14.2%) had brain edema (living, 16.1% vs. deceased, 11.3%; P = 0.269) before liver transplantation. There were no significant differences in in-hospital mortality (living, 11.8% vs. deceased, 15.1%; P = 0.435), 10-year overall survival (living, 90.8% vs. deceased, 84.0%; P = 0.096), and graft survival (living, 83.5% vs. deceased, 71.3%; P = 0.051). However, postoperatively, the mean intensive care unit stay was shorter in the LDLT group (5.0 days vs. 9.5 days, P < 0.001). In-hospital mortality was associated with vasopressor use (odds ratio [OR], 3.40; 95% confidence interval [CI], 1.45-7.96; P = 0.005) and brain edema (OR, 2.75; 95% CI, 1.16-6.52; P = 0.022) of recipient at the time of transplantation. However, LDLT (OR, 1.26; 95% CI, 0.59-2.66; P = 0.553) was not independently associated with in-hospital mortality.ConclusionLDLT is feasible for acute liver failure when organs from deceased donors are not available.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142264712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exposure to postoperative hypothermia and its association with complications after major abdominal surgery: a retrospective cohort study. 腹部大手术后低体温及其与并发症的关系:一项回顾性队列研究。
IF 1.2 4区 医学 Q3 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-07-30 DOI: 10.4174/astr.2024.107.2.120
Saeyeon Kim, In-Ae Song, Tak Kyu Oh

Purpose: Many patients who undergo major abdominal surgery experience inadvertent hypothermia during the perioperative period. This study aimed to identify risk factors related to postoperative hypothermia and their association with postoperative complications.

Methods: This retrospective cohort study used data from Seoul National University Bundang Hospital, a tertiary university medical center in South Korea, between January 1, 2018 and December 31, 2022. We included patients aged ≥18 years who underwent elective major abdominal surgery for more than 2 hours in the operating room. The patients were categorized into the hypothermia (body temperature <36.5℃) and non-hypothermia (body temperature ≥36.5℃) groups.

Results: The study sample comprised 30,194 patients, and we classified 21,293 and 8,901 into the hypothermic and non-hypothermic groups, respectively. Some factors associated with the occurrence of postoperative hypothermia included the type of surgery. In the multivariable logistic regression model, the incidence of postoperative complications was 9% higher in the hypothermia group than in the non-hypothermic group (odds ratio [OR], 1.09; 95% confidence interval [CI], 1.01-1.19; P = 0.040). Among postoperative complications, the hypothermic group showed a 14% higher incidence of acute kidney injury (OR, 1.14; 95% CI, 1.04-1.25; P = 0.007) than the non-hypothermic group.

Conclusion: The appearance of postoperative hypothermia during the first 30 minutes of the recovery period was significantly associated with the appearance of postoperative complications, especially acute kidney injury. However, further studies are required to validate these findings.

目的:许多接受腹部大手术的患者在围手术期会不慎出现低体温。本研究旨在确定与术后低体温有关的风险因素及其与术后并发症的关系:这项回顾性队列研究使用了韩国三级大学医疗中心首尔国立大学盆唐医院在2018年1月1日至2022年12月31日期间的数据。我们纳入了年龄≥18岁、在手术室接受择期大腹部手术时间超过2小时的患者。这些患者被分为体温过低(体温结果:研究样本包括 30,194 名患者,我们将 21,293 名患者和 8,901 名患者分别分为低体温组和非低体温组。与术后低体温相关的一些因素包括手术类型。在多变量逻辑回归模型中,低体温组的术后并发症发生率比非低体温组高 9%(几率比 [OR],1.09;95% 置信区间 [CI],1.01-1.19;P = 0.040)。在术后并发症中,低体温组急性肾损伤的发生率比非低体温组高14%(OR,1.14;95% CI,1.04-1.25;P = 0.007):结论:术后恢复期前 30 分钟内出现低体温与术后并发症,尤其是急性肾损伤的出现有显著相关性。然而,还需要进一步的研究来验证这些发现。
{"title":"Exposure to postoperative hypothermia and its association with complications after major abdominal surgery: a retrospective cohort study.","authors":"Saeyeon Kim, In-Ae Song, Tak Kyu Oh","doi":"10.4174/astr.2024.107.2.120","DOIUrl":"10.4174/astr.2024.107.2.120","url":null,"abstract":"<p><strong>Purpose: </strong>Many patients who undergo major abdominal surgery experience inadvertent hypothermia during the perioperative period. This study aimed to identify risk factors related to postoperative hypothermia and their association with postoperative complications.</p><p><strong>Methods: </strong>This retrospective cohort study used data from Seoul National University Bundang Hospital, a tertiary university medical center in South Korea, between January 1, 2018 and December 31, 2022. We included patients aged ≥18 years who underwent elective major abdominal surgery for more than 2 hours in the operating room. The patients were categorized into the hypothermia (body temperature <36.5℃) and non-hypothermia (body temperature ≥36.5℃) groups.</p><p><strong>Results: </strong>The study sample comprised 30,194 patients, and we classified 21,293 and 8,901 into the hypothermic and non-hypothermic groups, respectively. Some factors associated with the occurrence of postoperative hypothermia included the type of surgery. In the multivariable logistic regression model, the incidence of postoperative complications was 9% higher in the hypothermia group than in the non-hypothermic group (odds ratio [OR], 1.09; 95% confidence interval [CI], 1.01-1.19; P = 0.040). Among postoperative complications, the hypothermic group showed a 14% higher incidence of acute kidney injury (OR, 1.14; 95% CI, 1.04-1.25; P = 0.007) than the non-hypothermic group.</p><p><strong>Conclusion: </strong>The appearance of postoperative hypothermia during the first 30 minutes of the recovery period was significantly associated with the appearance of postoperative complications, especially acute kidney injury. However, further studies are required to validate these findings.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11317361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141974987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surface treatment of artificial implants with hybrid nanolayers: results of antibacterial tests, leachates and scanning electron microscope analysis. 用混合纳米涂层对人工植入物进行表面处理:抗菌测试、浸出物和扫描电子显微镜分析的结果。
IF 1.2 4区 医学 Q3 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-07-30 DOI: 10.4174/astr.2024.107.2.108
Jiřĺ Škach, Irena Šlamborová, Peter Hromádka, Petr Exnar, Robert Gürlich

Purpose: The aim of this study was to evaluate the antibacterial efficacy of surface-treated hernia implants modified by a hybrid nanolayer with incorporated Ag, Cu, and Zn cations using the sol-gel method.

Methods: The materials (polypropylene, polyester, and polyvinylidene difluoride) were activated by vacuum plasma treatment or UV C radiation, then modified and tested for bacterial strains of Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive). The AATCC 100 (2019) method for quantitative and the ISO 20645 agar plate propagation method for qualitative evaluation of microbiological efficacy were used. The gradual release of incorporated ions was monitored over time in simulated body fluids (blood plasma, peritoneal fluid) and physiological saline using an inductively coupled plasma mass spectrometer. The thickness and the homogeneity of the layers were measured for individual random samples with scanning electron microscope analysis (SEMA) and evaluated with an elemental analysis.

Results: Qualitative and quantitative microbiological tests clearly show the great suitability of vacuum plasma and UV C with sol AD30 (dilution 1:1) surface treatment of the implants. The absolute concentration of Ag, Cu, and Zn cations in leachates was very low. SEMA showed a high degree of homogeneity of the layer and only very rare nanocracks by all tested materials appear after mechanical stress.

Conclusion: This study confirms that surface treatment of meshes using the sol-gel method significantly increases the antibacterial properties. The nanolayers are sufficiently mechanically resistant and stable and pose no threat to health.

目的:本研究的目的是评估采用溶胶-凝胶法对加入 Ag、Cu 和 Zn 阳离子的混合纳米层修饰的表面处理疝植入物的抗菌效果:材料(聚丙烯、聚酯和聚偏二氟乙烯)经真空等离子处理或紫外线 C 辐射活化后进行改性,并对大肠杆菌(革兰氏阴性)和金黄色葡萄球菌(革兰氏阳性)进行细菌菌株测试。微生物功效的定量评估采用 AATCC 100 (2019) 法,定性评估采用 ISO 20645 琼脂平板繁殖法。使用电感耦合等离子体质谱仪监测了在模拟体液(血浆、腹腔液)和生理盐水中随着时间推移逐渐释放的掺杂离子。通过扫描电子显微镜分析(SEMA)测量了随机样品的厚度和层的均匀性,并通过元素分析进行了评估:定性和定量微生物测试清楚地表明,真空等离子体和紫外线 C 与溶胶 AD30(稀释度 1:1)对植入物的表面处理非常合适。浸出液中的银、铜和锌阳离子的绝对浓度非常低。SEMA 显示出高度均匀的层,在机械应力作用下,所有测试材料仅出现极少量的纳米裂缝:本研究证实,使用溶胶-凝胶法对网格进行表面处理可显著提高抗菌性能。纳米层具有足够的机械耐受性和稳定性,不会对健康造成威胁。
{"title":"Surface treatment of artificial implants with hybrid nanolayers: results of antibacterial tests, leachates and scanning electron microscope analysis.","authors":"Jiřĺ Škach, Irena Šlamborová, Peter Hromádka, Petr Exnar, Robert Gürlich","doi":"10.4174/astr.2024.107.2.108","DOIUrl":"10.4174/astr.2024.107.2.108","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to evaluate the antibacterial efficacy of surface-treated hernia implants modified by a hybrid nanolayer with incorporated Ag, Cu, and Zn cations using the sol-gel method.</p><p><strong>Methods: </strong>The materials (polypropylene, polyester, and polyvinylidene difluoride) were activated by vacuum plasma treatment or UV C radiation, then modified and tested for bacterial strains of <i>Escherichia coli</i> (gram-negative) and <i>Staphylococcus aureus</i> (gram-positive). The AATCC 100 (2019) method for quantitative and the ISO 20645 agar plate propagation method for qualitative evaluation of microbiological efficacy were used. The gradual release of incorporated ions was monitored over time in simulated body fluids (blood plasma, peritoneal fluid) and physiological saline using an inductively coupled plasma mass spectrometer. The thickness and the homogeneity of the layers were measured for individual random samples with scanning electron microscope analysis (SEMA) and evaluated with an elemental analysis.</p><p><strong>Results: </strong>Qualitative and quantitative microbiological tests clearly show the great suitability of vacuum plasma and UV C with sol AD30 (dilution 1:1) surface treatment of the implants. The absolute concentration of Ag, Cu, and Zn cations in leachates was very low. SEMA showed a high degree of homogeneity of the layer and only very rare nanocracks by all tested materials appear after mechanical stress.</p><p><strong>Conclusion: </strong>This study confirms that surface treatment of meshes using the sol-gel method significantly increases the antibacterial properties. The nanolayers are sufficiently mechanically resistant and stable and pose no threat to health.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11317359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141974992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intracorporeal anastomosis in minimally invasive right hemicolectomy: a nationwide survey of the Korean Society of Coloproctology. 体腔内吻合术在微创右半结肠切除术中的应用:韩国结肠直肠协会的一项全国性调查。
IF 1.2 4区 医学 Q3 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-07-30 DOI: 10.4174/astr.2024.107.2.59
Song Soo Yang, Bong Hyeon Kye, Sang Hee Kang, Chang Hyun Kim, Ji Hoon Kim, Woo Ram Kim, Kil Yeon Lee, In Kyu Park

Purpose: We investigated the current practices and perceptions of colorectal surgeons in South Korea regarding intracorporeal ileocolic anastomosis (IIA) in minimally invasive right hemicolectomy (RHC).

Methods: Members of the Korean Society of Coloproctology (KSCP) participated in an online survey encompassing demographic information, surgical experiences, methods for IIA, and advantages, barriers, and perceptions of IIA. We performed a statistical analysis of survey results.

Results: Among the 1,074 KSCP members contacted, 178 responded to the survey. Most respondents were males aged 40-49 years with >10 years of experience who were affiliated with a tertiary healthcare facility. One hundred fifty-six respondents had performed <100 colorectal cancer surgeries annually. Fifty-nine respondents reported experiences of the IIA technique in minimally invasive RHC. Most respondents favored the isoperistaltic side-to-side (S-S) anastomosis and stapled S-S anastomosis, hand-sewn closure for the common channel, and the periumbilical area for primary specimen extraction. Respondents with IIA experience emphasized the reduction in postoperative complications as the primary reason for performing IIA, whereas respondents without IIA experience cited the lack of benefits as the main deterrent. Respondents commonly cited concerns regarding anastomotic leakage and intraabdominal contamination as the primary reasons for not performing IIA. Respondents with IIA experience demonstrated a more positive response towards attempting or transitioning to IIA than those without. Respondents with IIA experience prioritized self-sufficiency, whereas respondents without IIA experience prioritized proctorship and discussions of the initial cases.

Conclusion: Measures to standardize the IIA technique and appropriate training programs must be implemented to enhance its use in minimally invasive RHC.

目的:我们调查了韩国结直肠外科医生目前对微创右半结肠切除术(RHC)中体外回肠结肠吻合术(IIA)的做法和看法:韩国结肠直肠外科学会(KSCP)成员参与了一项在线调查,调查内容包括人口统计学信息、手术经验、IIA的方法以及IIA的优势、障碍和看法。我们对调查结果进行了统计分析:在我们联系的 1,074 名 KSCP 会员中,有 178 人对调查做出了回复。大多数受访者为男性,年龄在 40-49 岁之间,工作经验超过 10 年,隶属于一家三级医疗机构。156 名受访者曾进行过结肠癌手术:必须采取措施规范 IIA 技术并实施适当的培训计划,以提高其在微创 RHC 中的应用。
{"title":"Intracorporeal anastomosis in minimally invasive right hemicolectomy: a nationwide survey of the Korean Society of Coloproctology.","authors":"Song Soo Yang, Bong Hyeon Kye, Sang Hee Kang, Chang Hyun Kim, Ji Hoon Kim, Woo Ram Kim, Kil Yeon Lee, In Kyu Park","doi":"10.4174/astr.2024.107.2.59","DOIUrl":"10.4174/astr.2024.107.2.59","url":null,"abstract":"<p><strong>Purpose: </strong>We investigated the current practices and perceptions of colorectal surgeons in South Korea regarding intracorporeal ileocolic anastomosis (IIA) in minimally invasive right hemicolectomy (RHC).</p><p><strong>Methods: </strong>Members of the Korean Society of Coloproctology (KSCP) participated in an online survey encompassing demographic information, surgical experiences, methods for IIA, and advantages, barriers, and perceptions of IIA. We performed a statistical analysis of survey results.</p><p><strong>Results: </strong>Among the 1,074 KSCP members contacted, 178 responded to the survey. Most respondents were males aged 40-49 years with >10 years of experience who were affiliated with a tertiary healthcare facility. One hundred fifty-six respondents had performed <100 colorectal cancer surgeries annually. Fifty-nine respondents reported experiences of the IIA technique in minimally invasive RHC. Most respondents favored the isoperistaltic side-to-side (S-S) anastomosis and stapled S-S anastomosis, hand-sewn closure for the common channel, and the periumbilical area for primary specimen extraction. Respondents with IIA experience emphasized the reduction in postoperative complications as the primary reason for performing IIA, whereas respondents without IIA experience cited the lack of benefits as the main deterrent. Respondents commonly cited concerns regarding anastomotic leakage and intraabdominal contamination as the primary reasons for not performing IIA. Respondents with IIA experience demonstrated a more positive response towards attempting or transitioning to IIA than those without. Respondents with IIA experience prioritized self-sufficiency, whereas respondents without IIA experience prioritized proctorship and discussions of the initial cases.</p><p><strong>Conclusion: </strong>Measures to standardize the IIA technique and appropriate training programs must be implemented to enhance its use in minimally invasive RHC.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11317360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141974988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Learning curve analysis for hand-assisted laparoscopic living donor nephrectomy: an analysis of 96 consecutive cases performed by a trained gastrointestinal surgeon. 徒手辅助腹腔镜活体供体肾切除术的学习曲线分析:对一名训练有素的胃肠外科医生连续实施的 96 例病例的分析。
IF 1.2 4区 医学 Q3 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-07-30 DOI: 10.4174/astr.2024.107.2.81
Chang In Choi, Kyeong Jun Lee, Min Joo Kim, Jae-Kyun Park, Da Woon Kim, Hyo Jin Kim, Harin Rhee, Sang Heon Song, Eun Young Seong, Dae-Hwan Kim, Tae Yong Jeon, Hyuk Jae Jung

Purpose: This study aims to analyze the learning curve of hand-assisted laparoscopic living donor nephrectomy (HLDN) conducted by a trained gastrointestinal surgeon.

Methods: A retrospective analysis was performed on the perioperative clinical data of 96 consecutive patients who underwent HLDN from May 2013 to March 2023. The learning curve was evaluated using the cumulative sum (CUSUM) test based on operation time and risk-adjusted CUSUM for postoperative complications. Patients were divided into three groups (novice, development, and competency phases) based on changes in operation time. Patient demographics and perioperative outcomes were compared between each group.

Results: Among the patients, 35 were male, with a mean age of 48.9 ± 11.3 years and a mean body mass index (BMI) of 24.5 ± 3.2 kg/m2. The novice phase (phase 1) included the first 30 cases, with the development phase (phase 2) up to the 65th case. Operation times were significantly different across phases, averaging 263.2 ± 33.4, 211.1 ± 34.4, and 161.1 ± 31.3 minutes for phases 1, 2, and 3, respectively (P < 0.001). Blood loss decreased gradually across phases (phase 1, 264.7 ± 144.4 mL; phase 2, 239.7 ± 166.3 mL; phase 3, 198.8 ± 103.5 mL), though not statistically significant. BMI impacted operation time only in phase 1. Overall postoperative complications occurred in 13 cases (Clavien-Dindo grade I, 4 cases; grade II, 9 cases), with no significant differences across phases.

Conclusion: HLDN can be safely performed by a trained gastrointestinal surgeon, with approximately 30 cases needed to achieve proficiency.

目的:本研究旨在分析由训练有素的胃肠外科医生实施的手辅助腹腔镜活体供体肾切除术(HLDN)的学习曲线:方法:对2013年5月至2023年3月期间接受HLDN手术的96例连续患者的围手术期临床数据进行回顾性分析。使用基于手术时间的累积总和(CUSUM)检验和术后并发症的风险调整CUSUM来评估学习曲线。根据手术时间的变化,将患者分为三组(新手期、发展期和胜任期)。比较了各组患者的人口统计学特征和围手术期结果:患者中有 35 名男性,平均年龄为(48.9±11.3)岁,平均体重指数(BMI)为(24.5±3.2)kg/m2。新手阶段(第 1 阶段)包括前 30 个病例,发展阶段(第 2 阶段)直至第 65 个病例。各阶段的手术时间有明显差异,第一、第二和第三阶段的平均手术时间分别为 263.2 ± 33.4 分钟、211.1 ± 34.4 分钟和 161.1 ± 31.3 分钟(P < 0.001)。各阶段失血量逐渐减少(第 1 阶段,264.7 ± 144.4 mL;第 2 阶段,239.7 ± 166.3 mL;第 3 阶段,198.8 ± 103.5 mL),但无统计学意义。体重指数仅在第一阶段影响手术时间。术后并发症共 13 例(Clavien-Dindo I 级 4 例;II 级 9 例),各阶段无显著差异:结论:训练有素的胃肠外科医生可以安全地进行 HLDN 手术,大约需要 30 例才能达到熟练程度。
{"title":"Learning curve analysis for hand-assisted laparoscopic living donor nephrectomy: an analysis of 96 consecutive cases performed by a trained gastrointestinal surgeon.","authors":"Chang In Choi, Kyeong Jun Lee, Min Joo Kim, Jae-Kyun Park, Da Woon Kim, Hyo Jin Kim, Harin Rhee, Sang Heon Song, Eun Young Seong, Dae-Hwan Kim, Tae Yong Jeon, Hyuk Jae Jung","doi":"10.4174/astr.2024.107.2.81","DOIUrl":"10.4174/astr.2024.107.2.81","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to analyze the learning curve of hand-assisted laparoscopic living donor nephrectomy (HLDN) conducted by a trained gastrointestinal surgeon.</p><p><strong>Methods: </strong>A retrospective analysis was performed on the perioperative clinical data of 96 consecutive patients who underwent HLDN from May 2013 to March 2023. The learning curve was evaluated using the cumulative sum (CUSUM) test based on operation time and risk-adjusted CUSUM for postoperative complications. Patients were divided into three groups (novice, development, and competency phases) based on changes in operation time. Patient demographics and perioperative outcomes were compared between each group.</p><p><strong>Results: </strong>Among the patients, 35 were male, with a mean age of 48.9 ± 11.3 years and a mean body mass index (BMI) of 24.5 ± 3.2 kg/m<sup>2</sup>. The novice phase (phase 1) included the first 30 cases, with the development phase (phase 2) up to the 65th case. Operation times were significantly different across phases, averaging 263.2 ± 33.4, 211.1 ± 34.4, and 161.1 ± 31.3 minutes for phases 1, 2, and 3, respectively (P < 0.001). Blood loss decreased gradually across phases (phase 1, 264.7 ± 144.4 mL; phase 2, 239.7 ± 166.3 mL; phase 3, 198.8 ± 103.5 mL), though not statistically significant. BMI impacted operation time only in phase 1. Overall postoperative complications occurred in 13 cases (Clavien-Dindo grade I, 4 cases; grade II, 9 cases), with no significant differences across phases.</p><p><strong>Conclusion: </strong>HLDN can be safely performed by a trained gastrointestinal surgeon, with approximately 30 cases needed to achieve proficiency.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11317363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141974989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of obesity on the outcomes of laparoscopic adrenal surgery in patients with Cushing syndrome. 肥胖对库欣综合征患者腹腔镜肾上腺手术效果的影响。
IF 1.2 4区 医学 Q3 SURGERY Pub Date : 2024-08-01 Epub Date: 2024-07-30 DOI: 10.4174/astr.2024.107.2.100
Orkun Özbebit, Sedat Çarkıt, Mustafa Karaağaç, Mustafa Gök, Bahadır Öz, Serap Doğan, Figen Öztürk, Ahmet Öztürk, Alper Akcan

Purpose: The aim of this study is to investigate the effect of obesity on the results of laparoscopic adrenal surgery in patients with Cushing syndrome.

Methods: This retrospective study was performed in Department of General Surgery at Erciyes University School of Medicine between January 2010 and January 2023. Our analysis included Cushing syndrome patients who underwent unilateral laparoscopic adrenalectomy (LA) with the transabdominal lateral approach. All patients were evaluated in terms of age, sex, tumor diameter, body mass index (BMI), American Society of Anesthesiologists physical status classification, morbidities, surgery history, tumor side, operative time, conversion to open surgery, complications, and length of hospital stay.

Results: A total of 90 patients (75 females and 15 males) underwent a transperitoneal LA. Patients were divided into 2 groups according to their BMI: obese group (≥30 kg/m2; n = 53, 58.8%) and nonobese group (<30 kg/m2; n = 37, 41.2%). All patients were classified into 3 subgroups: obese patient group, BMI ≥30-39 kg/m2 (n = 23); morbidly obese patient group, BMI ≥40 kg/m2 (n = 14); and nonobese patient group, BMI <30 kg/m2 (n = 53). There was no significant difference in intraoperative complications, conversion to open surgery, operative time, or length of hospital stay between the groups. Only conversion to open surgery was a risk factor for postoperative complications in univariate and multivariate analyses (odds ratio, 15.4; 95% confidence interval, 1.277-185.599; P = 0.031).

Conclusion: Our results showed that LA is safe and effective in patients with Cushing syndrome with morbid obesity, allowing acceptable morbidity and length of hospital stay.

目的:本研究旨在探讨肥胖对库欣综合征患者腹腔镜肾上腺手术效果的影响:这项回顾性研究于 2010 年 1 月至 2023 年 1 月在埃尔希耶斯大学医学院普外科进行。我们的分析包括采用经腹外侧入路进行单侧腹腔镜肾上腺切除术(LA)的库欣综合征患者。我们对所有患者的年龄、性别、肿瘤直径、体重指数(BMI)、美国麻醉医师协会身体状况分类、发病率、手术史、肿瘤侧、手术时间、转为开放手术、并发症和住院时间进行了评估:共有 90 名患者(75 名女性和 15 名男性)接受了经腹腔 LA 手术。根据体重指数将患者分为两组:肥胖组(≥30 kg/m2;n = 53,58.8%)和非肥胖组(2;n = 37,41.2%)。所有患者被分为三个亚组:肥胖患者组,BMI ≥30-39 kg/m2(n = 23);病态肥胖患者组,BMI ≥40 kg/m2(n = 14);非肥胖患者组,BMI 2(n = 53)。两组患者在术中并发症、转为开腹手术、手术时间或住院时间方面无明显差异。在单变量和多变量分析中,只有转为开放手术是术后并发症的风险因素(几率比为15.4;95%置信区间为1.277-185.599;P = 0.031):我们的研究结果表明,LA对伴有病态肥胖的库欣综合征患者安全有效,发病率和住院时间均可接受。
{"title":"The effect of obesity on the outcomes of laparoscopic adrenal surgery in patients with Cushing syndrome.","authors":"Orkun Özbebit, Sedat Çarkıt, Mustafa Karaağaç, Mustafa Gök, Bahadır Öz, Serap Doğan, Figen Öztürk, Ahmet Öztürk, Alper Akcan","doi":"10.4174/astr.2024.107.2.100","DOIUrl":"10.4174/astr.2024.107.2.100","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study is to investigate the effect of obesity on the results of laparoscopic adrenal surgery in patients with Cushing syndrome.</p><p><strong>Methods: </strong>This retrospective study was performed in Department of General Surgery at Erciyes University School of Medicine between January 2010 and January 2023. Our analysis included Cushing syndrome patients who underwent unilateral laparoscopic adrenalectomy (LA) with the transabdominal lateral approach. All patients were evaluated in terms of age, sex, tumor diameter, body mass index (BMI), American Society of Anesthesiologists physical status classification, morbidities, surgery history, tumor side, operative time, conversion to open surgery, complications, and length of hospital stay.</p><p><strong>Results: </strong>A total of 90 patients (75 females and 15 males) underwent a transperitoneal LA. Patients were divided into 2 groups according to their BMI: obese group (≥30 kg/m<sup>2</sup>; n = 53, 58.8%) and nonobese group (<30 kg/m<sup>2</sup>; n = 37, 41.2%). All patients were classified into 3 subgroups: obese patient group, BMI ≥30-39 kg/m<sup>2</sup> (n = 23); morbidly obese patient group, BMI ≥40 kg/m<sup>2</sup> (n = 14); and nonobese patient group, BMI <30 kg/m<sup>2</sup> (n = 53). There was no significant difference in intraoperative complications, conversion to open surgery, operative time, or length of hospital stay between the groups. Only conversion to open surgery was a risk factor for postoperative complications in univariate and multivariate analyses (odds ratio, 15.4; 95% confidence interval, 1.277-185.599; P = 0.031).</p><p><strong>Conclusion: </strong>Our results showed that LA is safe and effective in patients with Cushing syndrome with morbid obesity, allowing acceptable morbidity and length of hospital stay.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11317362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141974946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Annals of Surgical Treatment and Research
全部 Geobiology Appl. Clay Sci. Geochim. Cosmochim. Acta J. Hydrol. Org. Geochem. Carbon Balance Manage. Contrib. Mineral. Petrol. Int. J. Biometeorol. IZV-PHYS SOLID EART+ J. Atmos. Chem. Acta Oceanolog. Sin. Acta Geophys. ACTA GEOL POL ACTA PETROL SIN ACTA GEOL SIN-ENGL AAPG Bull. Acta Geochimica Adv. Atmos. Sci. Adv. Meteorol. Am. J. Phys. Anthropol. Am. J. Sci. Am. Mineral. Annu. Rev. Earth Planet. Sci. Appl. Geochem. Aquat. Geochem. Ann. Glaciol. Archaeol. Anthropol. Sci. ARCHAEOMETRY ARCT ANTARCT ALP RES Asia-Pac. J. Atmos. Sci. ATMOSPHERE-BASEL Atmos. Res. Aust. J. Earth Sci. Atmos. Chem. Phys. Atmos. Meas. Tech. Basin Res. Big Earth Data BIOGEOSCIENCES Geostand. Geoanal. Res. GEOLOGY Geosci. J. Geochem. J. Geochem. Trans. Geosci. Front. Geol. Ore Deposits Global Biogeochem. Cycles Gondwana Res. Geochem. Int. Geol. J. Geophys. Prospect. Geosci. Model Dev. GEOL BELG GROUNDWATER Hydrogeol. J. Hydrol. Earth Syst. Sci. Hydrol. Processes Int. J. Climatol. Int. J. Earth Sci. Int. Geol. Rev. Int. J. Disaster Risk Reduct. Int. J. Geomech. Int. J. Geog. Inf. Sci. Isl. Arc J. Afr. Earth. Sci. J. Adv. Model. Earth Syst. J APPL METEOROL CLIM J. Atmos. Oceanic Technol. J. Atmos. Sol. Terr. Phys. J. Clim. J. Earth Sci. J. Earth Syst. Sci. J. Environ. Eng. Geophys. J. Geog. Sci. Mineral. Mag. Miner. Deposita Mon. Weather Rev. Nat. Hazards Earth Syst. Sci. Nat. Clim. Change Nat. Geosci. Ocean Dyn. Ocean and Coastal Research npj Clim. Atmos. Sci. Ocean Modell. Ocean Sci. Ore Geol. Rev. OCEAN SCI J Paleontol. J. PALAEOGEOGR PALAEOCL PERIOD MINERAL PETROLOGY+ Phys. Chem. Miner. Polar Sci. Prog. Oceanogr. Quat. Sci. Rev. Q. J. Eng. Geol. Hydrogeol. RADIOCARBON Pure Appl. Geophys. Resour. Geol. Rev. Geophys. Sediment. Geol.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1