Pub Date : 2026-01-19DOI: 10.1136/archdischild-2025-329602
Yincent Tse
{"title":"First century: Most cited papers in <i>Archives of Disease in Childhood</i>.","authors":"Yincent Tse","doi":"10.1136/archdischild-2025-329602","DOIUrl":"10.1136/archdischild-2025-329602","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":"123-127"},"PeriodicalIF":3.2,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145367446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-19DOI: 10.1136/archdischild-2025-328742
Zoe Rooke, Caroline Harris, Ina Schim van der Loeff, Ahmed Hegab, Louise Kenny, Laura Nabarro, Matthew Thomas, Marieke Emonts
{"title":"Cystic echinococcosis in a child.","authors":"Zoe Rooke, Caroline Harris, Ina Schim van der Loeff, Ahmed Hegab, Louise Kenny, Laura Nabarro, Matthew Thomas, Marieke Emonts","doi":"10.1136/archdischild-2025-328742","DOIUrl":"10.1136/archdischild-2025-328742","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":"185-186"},"PeriodicalIF":3.2,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145494292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1136/archdischild-2025-329995
C Ronny Cheung, Joanna O'Sullivan
{"title":"Improving primary care registration for children and young people.","authors":"C Ronny Cheung, Joanna O'Sullivan","doi":"10.1136/archdischild-2025-329995","DOIUrl":"https://doi.org/10.1136/archdischild-2025-329995","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145987830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-14DOI: 10.1136/archdischild-2025-329730
Theresa Walls
{"title":"Child death in the emergency department: what is known and what more can be done?","authors":"Theresa Walls","doi":"10.1136/archdischild-2025-329730","DOIUrl":"https://doi.org/10.1136/archdischild-2025-329730","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145984399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-14DOI: 10.1136/archdischild-2025-329509
Robin Dhersin, Estelle Trebucq, Marie Rimbert, Jérémie Rouger-Gaudichon, Florent Neumann, Pascal Chastagner, Grégory Guimard, Dominique Plantaz, Sandrine Billet, Wadih Abouchahla, Audrey Petit, Eric Jeziorski, Valérie Li Thiao Te, Nathalie Cheikh, Nathalie Aladjidi, Liana Carausu, Caroline Thomas, Audrey Grain, Joy Benadiba, Laurence Blanc, Elie Cousin, Aude Marie-Cardine, Despina Moshous, Marlène Pasquet, Julien Lejeune, Saba Azarnoush, Blandine Beaupain, Vincent Dubée, Isabelle Pellier, Jean Donadieu, Coralie Mallebranche
Background: Autoimmune neutropenia (AIN) is the main cause of chronic neutropenia in children, but its infectious consequences remain poorly studied. The primary objective of this study was to evaluate infectious events leading to emergency department or hospital admissions during the first 2 years following the diagnosis of AIN in children.
Methods: We performed a retrospective, multicentre analysis of medical records from 21 French university hospitals of patients aged under 18 years diagnosed with AIN with positive antineutrophils autoantibodies. We collected data on emergency room visits and hospitalisations in the 2 years following diagnosis, causes of these events, microbiology results, management and outcome.
Results: One hundred and sixty-eight patients were enrolled. Median age at diagnosis of AIN was 13 months. AIN was predominantly diagnosed during an infectious episode (n=120, 71%). In the 2 years of follow-up after diagnosis, 248 events of emergency room visits and/or hospitalisations were reported (0.77 per patient-year). The most frequent diagnoses were common childhood viral or bacterial infections. The incidence rate of severe infections was 0.003 per patient-year. Despite the predominance of viral infections, 177 episodes (71%) led to hospitalisation and 166 (68%) to the initiation of antibiotic therapy, for a median duration of 7 days (IQR 3-10).
Conclusion: The risk of severe infections in children with AIN is low. During follow-up, we suggest being attentive to signs of severity during fever, particularly in children over 3 years of age and/or with other immunological comorbidities but not proposing systematic hospitalisation or additional antibiotic therapy.
{"title":"Analysis of infectious complications in paediatric autoimmune neutropenia: a French nationwide retrospective cohort study.","authors":"Robin Dhersin, Estelle Trebucq, Marie Rimbert, Jérémie Rouger-Gaudichon, Florent Neumann, Pascal Chastagner, Grégory Guimard, Dominique Plantaz, Sandrine Billet, Wadih Abouchahla, Audrey Petit, Eric Jeziorski, Valérie Li Thiao Te, Nathalie Cheikh, Nathalie Aladjidi, Liana Carausu, Caroline Thomas, Audrey Grain, Joy Benadiba, Laurence Blanc, Elie Cousin, Aude Marie-Cardine, Despina Moshous, Marlène Pasquet, Julien Lejeune, Saba Azarnoush, Blandine Beaupain, Vincent Dubée, Isabelle Pellier, Jean Donadieu, Coralie Mallebranche","doi":"10.1136/archdischild-2025-329509","DOIUrl":"https://doi.org/10.1136/archdischild-2025-329509","url":null,"abstract":"<p><strong>Background: </strong>Autoimmune neutropenia (AIN) is the main cause of chronic neutropenia in children, but its infectious consequences remain poorly studied. The primary objective of this study was to evaluate infectious events leading to emergency department or hospital admissions during the first 2 years following the diagnosis of AIN in children.</p><p><strong>Methods: </strong>We performed a retrospective, multicentre analysis of medical records from 21 French university hospitals of patients aged under 18 years diagnosed with AIN with positive antineutrophils autoantibodies. We collected data on emergency room visits and hospitalisations in the 2 years following diagnosis, causes of these events, microbiology results, management and outcome.</p><p><strong>Results: </strong>One hundred and sixty-eight patients were enrolled. Median age at diagnosis of AIN was 13 months. AIN was predominantly diagnosed during an infectious episode (n=120, 71%). In the 2 years of follow-up after diagnosis, 248 events of emergency room visits and/or hospitalisations were reported (0.77 per patient-year). The most frequent diagnoses were common childhood viral or bacterial infections. The incidence rate of severe infections was 0.003 per patient-year. Despite the predominance of viral infections, 177 episodes (71%) led to hospitalisation and 166 (68%) to the initiation of antibiotic therapy, for a median duration of 7 days (IQR 3-10).</p><p><strong>Conclusion: </strong>The risk of severe infections in children with AIN is low. During follow-up, we suggest being attentive to signs of severity during fever, particularly in children over 3 years of age and/or with other immunological comorbidities but not proposing systematic hospitalisation or additional antibiotic therapy.</p>","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145984234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-14DOI: 10.1136/archdischild-2025-329898
Margaret DeJong
{"title":"Child mental health: some reflections on the past 100 years.","authors":"Margaret DeJong","doi":"10.1136/archdischild-2025-329898","DOIUrl":"https://doi.org/10.1136/archdischild-2025-329898","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145984420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1136/archdischild-2025-329890
Samuel Jake Riches, Kellen Beck-Sander, Anna Datsenko, Magdalena Olechowska, Suzannah August
{"title":"Familial generalised multiple glomangiomas in the paediatric population.","authors":"Samuel Jake Riches, Kellen Beck-Sander, Anna Datsenko, Magdalena Olechowska, Suzannah August","doi":"10.1136/archdischild-2025-329890","DOIUrl":"https://doi.org/10.1136/archdischild-2025-329890","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145942202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1136/archdischild-2025-329600
Phillip Harniess, Jennifer McAnuff, Niina Kolehmainen
{"title":"Selecting meaningful functional outcomes and measures: a persistent dilemma in child health trials.","authors":"Phillip Harniess, Jennifer McAnuff, Niina Kolehmainen","doi":"10.1136/archdischild-2025-329600","DOIUrl":"https://doi.org/10.1136/archdischild-2025-329600","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145942290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-08DOI: 10.1136/archdischild-2025-329891
Rakhee Shah, Dougal Hargreaves
{"title":"Autism, paracetamol and folic acid: the perils of health misinformation.","authors":"Rakhee Shah, Dougal Hargreaves","doi":"10.1136/archdischild-2025-329891","DOIUrl":"https://doi.org/10.1136/archdischild-2025-329891","url":null,"abstract":"","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-06DOI: 10.1136/archdischild-2025-329747
Nanette Ryan, Dominic Wilkinson, Julian Savulescu
Semaglutide, marketed as Ozempic, Wegovy and Rybelsus, has rapidly become one of the most prominent medications of recent years. Initially approved in 2021 for type 2 diabetes in adults, semaglutide is now authorised for obesity management in adults and children in several countries, including Germany, the UK, Denmark and the United Arab Emirates. Despite this broad regulatory approval, its paediatric use remains a subject of debate. Advocates highlight its potential to reduce cardiovascular risk and prevent obesity-related illness, while critics emphasise uncertainties about long-term safety, efficacy and impacts on child development.This paper examines the ethical challenges raised by prescribing semaglutide to children, focusing on access barriers, stigma and the neglect of structural determinants of obesity, and provides ethical recommendations for clinicians aimed at mitigating harm, supporting autonomy and promoting children's health.
{"title":"Ethical considerations for semaglutide use in children.","authors":"Nanette Ryan, Dominic Wilkinson, Julian Savulescu","doi":"10.1136/archdischild-2025-329747","DOIUrl":"https://doi.org/10.1136/archdischild-2025-329747","url":null,"abstract":"<p><p>Semaglutide, marketed as Ozempic, Wegovy and Rybelsus, has rapidly become one of the most prominent medications of recent years. Initially approved in 2021 for type 2 diabetes in adults, semaglutide is now authorised for obesity management in adults and children in several countries, including Germany, the UK, Denmark and the United Arab Emirates. Despite this broad regulatory approval, its paediatric use remains a subject of debate. Advocates highlight its potential to reduce cardiovascular risk and prevent obesity-related illness, while critics emphasise uncertainties about long-term safety, efficacy and impacts on child development.This paper examines the ethical challenges raised by prescribing semaglutide to children, focusing on access barriers, stigma and the neglect of structural determinants of obesity, and provides ethical recommendations for clinicians aimed at mitigating harm, supporting autonomy and promoting children's health.</p>","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145909694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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