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Mohs Surgery for Basal Cell Carcinoma: A Systematic Review Mohs手术治疗基底细胞癌:系统回顾
Pub Date : 2020-01-01 DOI: 10.20431/2456-0022.0501001
A. M. Benítez, E. Rodríguez, Alberto Robles Méndez, Hernández, R. Audirac, L. P. Hernández, Lourdes, R. A. López, A. A. Rodríguez
Keratinocyte carcinomas (KCs) are, by far, the most common malignancies worldwide and exceed the prevalence of all other cancers combined. Traditionally, approximately 80% of KC cases have been attributed to basal cell carcinoma (BCC) and 20% to squamous cell carcinoma (SCC). However, recent studies point to an increasing SCC incidence relative to BCC, moving the historical 4:1 ratio to 2.5:1 or even closer. [1]
到目前为止,角化细胞癌(KCs)是世界上最常见的恶性肿瘤,其患病率超过了所有其他癌症的总和。传统上,大约80%的KC病例归因于基底细胞癌(BCC), 20%归因于鳞状细胞癌(SCC)。然而,最近的研究表明,相对于BCC, SCC的发病率在增加,将历史上的4:1的比例移动到2.5:1,甚至更接近。[1]
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引用次数: 0
Primary Cicatricial Alopecia Successfully Treated with A Combination of Oral Zinc with Nd: YAG Laser. A Case Series of Five Patients 口服锌与Nd: YAG激光联合治疗原发性瘢痕性脱发疗效观察。五个病人的病例系列
Pub Date : 2020-01-01 DOI: 10.20431/2456-0022.0501002
R. Giménez-García, Dra Teresa E. Lázaro Cantalejo
Cicatricial (Scarring) alopecia (CA) refers to a group of uncommon inflammatory hair loss disorders which are characterized by the destruction of the hair follicle unit that is replaced by fibrous tissue and result in permanent hair loss. Clinically there is loss of visible follicular ostia. CAs are classified as primary cicatricial alopecia (PCA), secondary cicatricial alopecia and development/hereditary CA. In primary cicatricial alopecia (PCA), the hair follicle is the main target for destruction with sparing of the interfollicular reticular dermis. The inflammatory cells target and destroy the stem cells in the bulge area of hair follicles. PCA are divided into subgroups depending upon the predominant inflammatory infiltrates. The neutrophilic PCA group comprises folliculitis decalvans (FD) and dissecting cellulitis/folliculitis of the scalp (perifolliculitis abscedens et suffodiens) [1-5]. We here report five cases PCA showing complete remission after treatment based on oral zinc in combination with Nd:YAG laser
瘢痕性脱发(CA)是指一组罕见的炎症性脱发疾病,其特征是毛囊单位被纤维组织所取代,并导致永久性脱发。临床上可见滤泡口缺失。CA分为原发性瘢痕性脱发(PCA)、继发性瘢痕性脱发和发展/遗传性CA。在原发性瘢痕性脱发(PCA)中,毛囊是破坏的主要目标,保留了毛囊间网状真皮。炎性细胞以毛囊膨出区域的干细胞为目标并破坏它们。根据主要的炎症浸润,PCA分为亚组。中性粒细胞PCA组包括脱斑状毛囊炎(FD)和剥离性蜂窝织炎/头皮毛囊炎(脱落性毛囊炎)[1-5]。我们在此报告5例PCA患者在口服锌联合Nd:YAG激光治疗后完全缓解
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引用次数: 0
Isolation and Characterization of Some Fungi Associated with Superficial Fungal Infections 浅表真菌感染相关真菌的分离与鉴定
Pub Date : 2020-01-01 DOI: 10.20431/2456-0022.0501003
S. Diso, S. Adam, Lurwan Mu’azu, M. Abdallah, Muhammad Ali
Dermatophytosis (syn. ringworm, tinea) is a zoonotic disease caused by a group of fungi called dermatophytes. Dermatophytosis has a worldwide distribution. It is the most frequent mycotic infection in both humans and animals [1]. Epidermophyton, Microsporum and Trichophyton are the main genera of dermatophytes. Based on their ecology, they are classified into anthropophilic, geophilic and zoophilic. They can directly infect human through a contact with the infested animal or human and indirectly by acquiring the infective materials from the environment [2]. The infection mainly occurs in young camels less than three years [3]. Trichophyton and Microsporum genera are responsible for the majority of human infections causing more virulent disease when the infection are transmitted from animal to human than that transmitted from human to human [4]. Outbreaks of Trichophyton infection transmitted from cattle to humans are also reported [5]. Tinea capitis (ringworm of the scalp) is the most common fungal infection in children. More than 90% of the infections are caused by Trichophyton tonsurans, and fewer than 5% are caused by Microsporum species [6].
皮肤癣是一种人畜共患疾病,由一组称为皮肤癣菌的真菌引起。皮肤癣病在世界各地都有分布。它是人类和动物中最常见的真菌感染[1]。表皮菌属、小孢子菌属和毛菌属是皮生植物的主要属。根据它们的生态,它们被分为亲人类、亲地球和亲动物。它们可以通过与被感染动物或人的接触直接感染人类,也可以通过从环境中获取感染物质间接感染人类[2]。感染主要发生在3岁以下的幼骆驼中[3]。毛菌属和小孢子菌属是大多数人类感染的罪魁祸首,当动物传染给人时,其致病性比人传染给人时更强[4]。牛向人类传播毛癣菌感染的暴发也有报道[5]。头癣(头皮癣)是儿童最常见的真菌感染。90%以上的感染是由毛癣菌引起的,而由小孢子菌引起的感染不到5%[6]。
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引用次数: 1
Sandpaper and Topical 5-Fluorouracil: A Different Therapeutic Modality for Acral Vitiligo 砂纸和外用5-氟尿嘧啶:肢端白癜风的不同治疗方式
Pub Date : 2019-01-01 DOI: 10.20431/2456-0022.0401001
Eman Asker, G. Mohammed, A. H. Gomaa, M. Eyada
Acral vitiligo (AV) is resistant to treatment [1, 2]. There are many factors help in developing this resistance. Low density of pilosebaceous follicles, melanocyte, melanocyte stem cell reservoirs, baseline epidermal stem cell factor from which the melanocytes could migrate, lower stem cell factor (SCF), c-kit, MHCII expression as well as lower density of Langerhans cells (LC), and high rate of koebnerization are playing roles in resistance of acral lesions [1,3,4]
肢端白癜风(AV)对治疗具有耐药性[1,2]。有许多因素有助于产生这种耐药性。毛囊皮脂腺毛囊的低密度、黑素细胞、黑素细胞干细胞库、黑色素细胞可迁移的基线表皮干细胞因子、较低的干细胞因子(SCF)、c-kit、MHCII表达以及较低的朗格汉斯细胞(LC)密度和高的koebnerization率在肢端病变的抵抗中发挥作用[1,3,4]
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引用次数: 2
Is there any Relation Exists between Moles on Face and Urine Leukocytes? 脸上的痣和尿中的白细胞有关系吗?
Pub Date : 2019-01-01 DOI: 10.20431/2456-0022.0402002
M. Qadir, Babar Saeed
Leukocytes or white platelets are cells that courses in our blood and body liquids and shield us from irresistible maladies or outside substances. Basophils, eosinophils, neutrophils, lymphocytes and monocytes are principle kinds of white platelets. Five fundamental sorts. White platelets have short life cycle, living from 10 days to about a month and they got and created from multipotent cell. They assume critical job in blood thickening, immerse microscopic organisms and produce antibodies. Leukocytes esterase is a compound found in leukocytes.
白细胞或血小板是在我们的血液和体液中流动的细胞,保护我们免受不可抗拒的疾病或外界物质的侵害。嗜碱性粒细胞、嗜酸性粒细胞、中性粒细胞、淋巴细胞和单核细胞是白细胞的主要种类。五种基本类型。白细胞的生命周期很短,从10天到一个月不等,它们是由多能细胞形成的。它们在血液增稠、浸泡微生物和产生抗体中起着至关重要的作用。白细胞酯酶是一种在白细胞中发现的化合物。
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引用次数: 0
Psoriasiform Febrile Ulceronecrotic Mucha Habermann Disease: A New Clinical Presentation of a Case Report from Upper Egypt 牛皮癣样发热性溃疡坏死Mucha Habermann病:上埃及病例报告的新临床表现
Pub Date : 2019-01-01 DOI: 10.20431/2456-0022.0402001
A. Mahran, Alaa Ghazally, Y. Salah, M. Ghazaly, A. Ahmed
FUMHD is a rare life-threatening variant of pityriasis lichenoides et varioliformis acuta (PLEVA) that is characterized clinically by rapidly progressive necrotic and ulcerating skin lesions together with high fever and various systemic affections. Histological characteristics are typical of PLEVA. The exact pathogenesis of FUMHD remains unclear, with no universally effective treatment [1]. As far as we know, only one case was reported in our country (Lower Egypt) in children by Nofel et al in 2016 [2]. However, no cases were reported from Upper Egypt.
FUMHD是一种罕见的危及生命的急性地衣样变性糠疹(PLEVA)变种,其临床特征是快速进展的坏死和溃疡性皮肤病变,并伴有高烧和各种全身病变。组织学特征是典型的PLEVA。FUMHD的确切发病机制尚不清楚,没有普遍有效的治疗方法[1]。据我们所知,2016年Nofel等在我国(下埃及)仅报告了1例儿童病例[2]。然而,上埃及没有报告病例。
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引用次数: 0
Characterization and Determination of Antibiotic Sensitivity Profile of Pseudomonasaeruginosa Isolated from Infected Wound 感染创面铜绿假单胞菌的鉴定及敏感性分析
Pub Date : 2019-01-01 DOI: 10.20431/2456-0022.0402004
Muhammad Ali, S. Diso, I. S. Ibrahim, Sumayya A. Wayya
Microbial resistance to antibiotics is one of the most serious health threats threatening human well-being today. Antibiotic resistance is a type of drug resistance where a microorganism is able to survive exposure to an antibiotic [1]. Infections from resistant bacteria are now too common and some pathogens have even become resistant to multiple types or classes of antibiotics. The widespread use of antibiotics both inside and outside of medicine is playing a significant role in the emergence of resistant bacteria [2]. One such microbial resistance of much interest nowadays to the scientific world in general and medical perspective in particular is the resistance of Pseudomonas aeruginosato different class of antibiotics.
微生物对抗生素的耐药性是当今威胁人类福祉的最严重的健康威胁之一。抗生素耐药性是指微生物能够在暴露于抗生素下存活的一种耐药性[1]。耐药细菌引起的感染现在太常见了,一些病原体甚至对多种类型或类别的抗生素产生了耐药性。药物内外抗生素的广泛使用是耐药菌出现的重要原因[2]。一个这样的微生物耐药性,现在非常感兴趣的科学界一般和医学的角度来看,特别是铜绿假单胞菌对不同种类的抗生素的耐药性。
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引用次数: 0
Nanobionics - Nanoscale View of a Biological System 纳米仿生学-生物系统的纳米尺度观点
Pub Date : 2019-01-01 DOI: 10.20431/2456-0022.0401003
T. Khan
Nanobionics is covering all the future scientific domains by studying biological system at nano scale. This technology is employed in various disciplines such as agriculture, textile, mycology and medicine. Nanobionics plays a platform for scientists to fabricate specific nanoparticles that can be easily embedded in a biological system to enhance its functioning and performance.
纳米仿生学通过在纳米尺度上研究生物系统,涵盖了未来所有的科学领域。这项技术被应用于农业、纺织、真菌学和医学等各个学科。纳米仿生学为科学家制造特定的纳米颗粒提供了一个平台,这些纳米颗粒可以很容易地嵌入生物系统中,以增强其功能和性能。
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引用次数: 2
Micelles-A Brief Insight 胶束——一个简短的见解
Pub Date : 2019-01-01 DOI: 10.20431/2456-0022.0401004
N. Khan
Micelle is formed by the aggregation of several atoms, electrically charged molecules etc, attaining a spherical assembly which is hydrophobic from the inside and hydrophilic from the outer surface enabling its interaction with water molecule [1, 2]. Micelles exhibits high degree of compatibility with other biological molecules [3]. Thus displayed high stability with the potential to solubilise weakly soluble drugs [4, 5].
胶束是由几个原子、带电分子等聚集而成,形成一个内疏水、外亲水的球形组装体,使其能够与水分子相互作用[1,2]。胶束与其他生物分子具有高度的相容性[3]。因此显示出高稳定性,具有溶解弱溶性药物的潜力[4,5]。
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引用次数: 0
Itch, Revisited 痒,重新审视
Pub Date : 2019-01-01 DOI: 10.20431/2456-0022.0402003
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引用次数: 0
期刊
ARC Journal of Dermatology
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