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Barriers and benefits to leisure-time physical activity among older Mexican Americans. 老年墨西哥裔美国人闲暇时间体育活动的障碍和益处。
Pub Date : 2000-09-01 DOI: 10.1001/archfami.9.9.892
C P Mouton, W L Calmbach, R Dhanda, D V Espino, H Hazuda

Objective: To identify the perceived barriers to and benefits of leisure-time physical activity among older Mexican Americans (MA) and European Americans (EA).

Design: Cross-sectional survey using in-home interviews of subjects.

Setting: Subjects recruited from 10 family practice offices in South Texas that are part of a practice-based research network.

Participants: Two hundred ten MA and EA adults, aged 60 years and older, interviewed between April 1994 and April 1996.

Measurements: The perceived benefits and barriers summary score from the San Diego Health and Exercise Questionnaire, the Minnesota Leisure Time Physical Activity Questionnaire, body mass index, chronic diseases, depressive symptoms, and demographics.

Main results: Older MA reported greater perceived benefits to physical activity and fewer perceived barriers than older MA while having lower levels of habitual physical activity. Lower levels of education, male sex, higher body mass index, and older age were also associated with lower levels of habitual physical activity.

Conclusions: Although MA reported lower levels of physical activity, they perceived greater benefits and fewer barriers to physical activity. These attitudes about physical activity held by older MA may present an opportunity to encourage greater levels of physical activity throughout this population.

目的:确定老年墨西哥裔美国人(MA)和欧洲裔美国人(EA)的休闲时间体育活动的感知障碍和益处。设计:采用家庭访谈的横断面调查。背景:研究对象从南德克萨斯州的10个家庭诊所招募,这些诊所是基于实践的研究网络的一部分。参与者:1994年4月至1996年4月期间接受采访的210名MA和EA成年人,年龄在60岁及以上。测量方法:从圣地亚哥健康和运动问卷、明尼苏达休闲时间体育活动问卷、体重指数、慢性疾病、抑郁症状和人口统计数据中获得的感知益处和障碍总结得分。主要结果:与习惯体育活动水平较低的老年MA相比,老年MA报告了更多的体育活动的感知益处和更少的感知障碍。受教育程度较低、性别为男性、身体质量指数较高和年龄较大也与习惯性体育活动水平较低有关。结论:尽管MA报告的体力活动水平较低,但他们认为体力活动的益处更大,障碍更少。老年MA对体育活动的态度可能为鼓励整个人群进行更高水平的体育活动提供了机会。
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引用次数: 46
Good grief. 好悲伤。
Pub Date : 2000-09-01 DOI: 10.1001/archfami.9.9.833
C G Olsen
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引用次数: 0
Detecting symptoms of alcohol abuse in primary care settings. 在初级保健机构检测酒精滥用症状。
Pub Date : 2000-09-01 DOI: 10.1001/archfami.9.9.814
W H McQuade, S M Levy, L R Yanek, S W Davis, M R Liepman

Background: Studies on alcohol abuse are frequently based on patients who meet minimum diagnostic criteria, thus ignoring patients with individual symptoms of harmful or hazardous use. Consequently, we are unable to characterize alcohol-abusing patients with sufficient clarity to effectively focus screening for primary prevention.

Objective: To determine the prevalence of harmful and hazardous use of alcohol, assess screening instruments for detecting alcohol abuse or dependence, and assess the impact of alcohol use on other diagnoses treated in outpatient settings.

Design: Survey (cross-sectional study).

Setting: Hospital-based outpatient clinic.

Participants: Three hundred randomly selected adults (aged 18 years and older).

Main outcome measure: Diagnosis of alcohol abuse or dependence based on the Diagnostic Interview Schedule (DIS).

Results: About 18% met DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) criteria of abuse or dependence while almost 50% had at least one symptom of harmful or hazardous use. The T-ACE questionnaire, a modified version of the CAGE questionnaire, was the most effective screening instrument for both men and women. Selected diagnoses, personal characteristics such as family history of alcohol abuse, and self-reported patterns of alcohol use could identify patients likely to meet diagnostic criteria.

Conclusions: Many symptoms of substance use disorders are not adequately addressed in outpatient practice. Little is known about how alcohol use in varying quantities affects health care utilization and treatment of conditions commonly seen in outpatient medicine. Consequently, we lack a full appreciation of the burden of disease borne by alcohol use and have yet to achieve a universally accepted method of approaching primary and secondary prevention of alcohol-related problems.

背景:关于酒精滥用的研究通常是基于满足最低诊断标准的患者,从而忽略了具有有害或危险使用个体症状的患者。因此,我们无法充分明确酒精滥用患者的特征,从而有效地集中筛查进行一级预防。目的:确定有害和危险使用酒精的患病率,评估检测酒精滥用或依赖的筛查工具,并评估酒精使用对门诊治疗的其他诊断的影响。设计:调查(横断面研究)。地点:医院门诊。参与者:随机选择300名成年人(18岁及以上)。主要结果测量:基于诊断访谈表(DIS)的酒精滥用或依赖诊断。结果:约18%的人符合DSM-IV(精神障碍诊断与统计手册,第四版)滥用或依赖的标准,而近50%的人至少有一种有害或危险使用的症状。T-ACE问卷是CAGE问卷的改良版,对男性和女性都是最有效的筛查工具。选定的诊断、个人特征(如酒精滥用家族史)和自我报告的酒精使用模式可以确定可能符合诊断标准的患者。结论:药物使用障碍的许多症状在门诊实践中没有得到充分解决。对于不同数量的酒精使用如何影响医疗保健的利用和门诊医学中常见的疾病的治疗,人们知之甚少。因此,我们没有充分认识到酒精使用所带来的疾病负担,也尚未找到一种普遍接受的方法来处理与酒精有关的问题的一级和二级预防。
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引用次数: 59
Prevalence of anxiety, depression, and substance use disorders in an urban general medicine practice. 城市全科医学实践中焦虑、抑郁和物质使用障碍的患病率。
Pub Date : 2000-09-01 DOI: 10.1001/archfami.9.9.876
M Olfson, S Shea, A Feder, M Fuentes, Y Nomura, M Gameroff, M M Weissman

Background: Most research on the prevalence of mental disorders in primary care has been conducted in practices that serve middle- and upper-income patients.

Objective: To determine the prevalence of major mental disorders in a primary care practice that serves a predominantly low-income immigrant patient population.

Design: Cross-sectional survey; criterion standard.

Setting: Urban general medicine practice.

Participants: Systematic sample of consecutive adult patients with scheduled appointments. Of 1266 approached eligible patients, 1007 (80%) participated.

Main outcome measures: PRIME-MD Patient Health Questionnaire major depression, generalized anxiety disorder, panic disorder, alcohol use disorder, and suicidal ideation; drug use disorder; functional status; work loss; family distress; and mental health treatment.

Results: Major depression (18. 9%), generalized anxiety (14.8%), panic (8.3%), and substance use (7. 9%) disorders and suicidal ideation (7.1%) were highly prevalent. Many patients had more than 1 disorder (range, 36.3% [substance use disorder] to 76.9% [panic disorder]). In multivariate analyses, each disorder was significantly associated with an increase in impairment after controlling for demographic characteristics, perceived health, and the other disorders. A minority of patients with each disorder (range, 22.5% [substance use disorder] to 46.4% [panic disorder]) reported receiving mental health treatment in the last month.

Conclusions: Clinically significant depression, anxiety, substance use, and suicidal ideation are quite common in this practice and associated with significant functional impairment. Primary care practices that serve poor urban immigrant populations have a critical need to provide access to mental health services. Arch Fam Med. 2000;9:876-883

背景:大多数关于初级保健中精神障碍患病率的研究都是在服务中高收入患者的实践中进行的。目的:确定主要服务于低收入移民患者人群的初级保健实践中主要精神障碍的患病率。设计:横断面调查;标准的标准。背景:城市全科医学实践。参与者:系统抽样的连续成人患者的预约。在1266名接近的符合条件的患者中,1007名(80%)参与了研究。主要结局指标:主要抑郁、广泛性焦虑障碍、惊恐障碍、酒精使用障碍和自杀意念;药物使用障碍;功能状态;工作损失;家庭的痛苦;以及心理健康治疗。结果:重度抑郁(18。9%),广泛性焦虑(14.8%),恐慌(8.3%)和物质使用(7.7%)。9%)精神障碍和自杀意念(7.1%)非常普遍。许多患者有一种以上的障碍(范围从36.3%[物质使用障碍]到76.9%[恐慌障碍])。在多变量分析中,在控制了人口统计学特征、感知健康和其他疾病之后,每种疾病都与损伤的增加显著相关。每种障碍的少数患者(范围从22.5%[物质使用障碍]到46.4%[恐慌障碍])报告在上个月接受了心理健康治疗。结论:临床显著的抑郁、焦虑、药物使用和自杀意念在这一实践中相当普遍,并与显著的功能损害相关。为贫穷的城市移民人口提供服务的初级保健做法迫切需要提供获得精神卫生服务的机会。中华医学杂志。2000;9:876-883
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引用次数: 283
A questionnaire survey of family practice physicians' perceptions of bereavement care. 家庭医生对丧亲护理认知的问卷调查。
Pub Date : 2000-09-01 DOI: 10.1001/archfami.9.9.822
J P Lemkau, B Mann, D Little, P Whitecar, P Hershberger, J A Schumm

Survey responses were obtained from 113 family physicians in an exploratory investigation of bereavement care by family physicians. Respondents generally indicated that they believed that bereavement presented significant health risks to their patients and that the identification and treatment of bereaved patients was an important part of their role. However, physicians were highly variable in how they reported identifying and responding to bereaved patients in terms of counseling, addressing spiritual concerns, and medically treating symptoms. The "grief-responsive" physician is described based on these data. We document the interest and need for training in bereavement care.

本文对113名家庭医生的丧亲护理进行了探索性调查。答复者普遍表示,他们认为丧亲之痛对其病人的健康构成重大风险,查明和治疗丧亲之痛病人是其职责的重要组成部分。然而,医生们在如何识别和回应丧亲患者的咨询、解决精神问题和治疗症状方面存在很大差异。“对悲伤有反应”的医生是根据这些数据来描述的。我们记录了对丧亲护理培训的兴趣和需求。
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引用次数: 27
Sexual orientation and health: comparisons in the women's health initiative sample. 性取向与健康:妇女健康倡议样本的比较。
Pub Date : 2000-09-01 DOI: 10.1001/archfami.9.9.843
B G Valanis, D J Bowen, T Bassford, E Whitlock, P Charney, R A Carter

Context: Little is known about older lesbian and bisexual women. Existing research rarely compares characteristics of these women with comparable heterosexual women.

Objective: To compare heterosexual and nonheterosexual women 50 to 79 years on specific demographic characteristics, psychosocial risk factors, screening practices, and other health-related behaviors associated with increased risk for developing particular diseases or disease outcomes.

Design: Analysis of data from 93,311 participants in the Women's Health Initiative (WHI) study of health in postmenopausal women, comparing characteristics of 5 groups: heterosexuals, bisexuals, lifetime lesbians, adult lesbians, and those who never had sex as an adult.

Setting: Subjects were recruited at 40 WHI study centers nationwide representing a range of geographic and ethnic diversity.

Participants: Postmenopausal women aged 50 to 79 years who met WHI eligibility criteria, signed an informed consent to participate in the WHI clinical trial(s) or observational study, and responded to the baseline questions on sexual orientation.

Main outcome measures: Demographic characteristics, psychosocial risk factors, recency of screening tests, and other health-related behaviors as assessed on the WHI baseline questionnaire.

Results: Although of higher socioeconomic status than the heterosexuals, the lesbian and bisexual women more often used alcohol and cigarettes, exhibited other risk factors for reproductive cancers and cardiovascular disease, and scored lower on measures of mental health and social support. Notable is the 35% of lesbians and 81% of bisexual women who have been pregnant. Women reporting that they never had sex as an adult had lower rates of Papanicolaou screening and hormone replacement therapy use than other groups.

Conclusions: This sample of older lesbian and bisexual women from WHI shows many of the same health behaviors, demographic, and psychosocial risk factors reported in the literature for their younger counterparts, despite their higher socioeconomic status and access to health care. The lower rates of recommended screening services and higher prevalence of obesity, smoking, alcohol use, and lower intake of fruit and vegetables among these women compared with heterosexual women indicate unmet needs that require effective interactions between care providers and nonheterosexual women.

背景:人们对老年女同性恋和双性恋女性知之甚少。现有的研究很少将这些女性的特征与异性恋女性进行比较。目的:比较50 - 79岁异性恋和非异性恋女性的特定人口统计学特征、社会心理风险因素、筛查做法和其他与特定疾病或疾病结局风险增加相关的健康相关行为。设计:分析来自妇女健康倡议(WHI)绝经后妇女健康研究的93311名参与者的数据,比较5组的特征:异性恋者、双性恋者、终身女同性恋者、成年女同性恋者和成年后从未有过性行为的人。背景:研究对象在全国40个WHI研究中心招募,代表了地理和种族的多样性。参与者:年龄在50 - 79岁的绝经后妇女,符合WHI的资格标准,签署知情同意书参加WHI临床试验或观察性研究,并回答性取向的基线问题。主要结果测量指标:人口统计学特征、社会心理风险因素、筛查试验的近代性,以及在WHI基线问卷上评估的其他与健康相关的行为。结果:虽然女同性恋和双性恋女性的社会经济地位高于异性恋,但她们更经常使用酒精和香烟,表现出其他生殖癌症和心血管疾病的危险因素,在心理健康和社会支持方面得分较低。值得注意的是,35%的女同性恋和81%的双性恋女性怀孕过。报告称,成年后从未有过性行为的女性接受帕帕尼科劳筛查和激素替代疗法的比例低于其他群体。结论:来自WHI的老年女同性恋和双性恋女性的样本显示,尽管她们的社会经济地位更高,获得医疗保健的机会也更多,但她们的许多健康行为、人口统计学和心理社会风险因素与文献中报道的年轻女性相同。与异性恋妇女相比,这些妇女的推荐筛查服务率较低,肥胖、吸烟、饮酒的流行率较高,水果和蔬菜的摄入量也较低,这表明需要护理提供者和非异性恋妇女之间有效的互动才能满足需求。
{"title":"Sexual orientation and health: comparisons in the women's health initiative sample.","authors":"B G Valanis,&nbsp;D J Bowen,&nbsp;T Bassford,&nbsp;E Whitlock,&nbsp;P Charney,&nbsp;R A Carter","doi":"10.1001/archfami.9.9.843","DOIUrl":"https://doi.org/10.1001/archfami.9.9.843","url":null,"abstract":"<p><strong>Context: </strong>Little is known about older lesbian and bisexual women. Existing research rarely compares characteristics of these women with comparable heterosexual women.</p><p><strong>Objective: </strong>To compare heterosexual and nonheterosexual women 50 to 79 years on specific demographic characteristics, psychosocial risk factors, screening practices, and other health-related behaviors associated with increased risk for developing particular diseases or disease outcomes.</p><p><strong>Design: </strong>Analysis of data from 93,311 participants in the Women's Health Initiative (WHI) study of health in postmenopausal women, comparing characteristics of 5 groups: heterosexuals, bisexuals, lifetime lesbians, adult lesbians, and those who never had sex as an adult.</p><p><strong>Setting: </strong>Subjects were recruited at 40 WHI study centers nationwide representing a range of geographic and ethnic diversity.</p><p><strong>Participants: </strong>Postmenopausal women aged 50 to 79 years who met WHI eligibility criteria, signed an informed consent to participate in the WHI clinical trial(s) or observational study, and responded to the baseline questions on sexual orientation.</p><p><strong>Main outcome measures: </strong>Demographic characteristics, psychosocial risk factors, recency of screening tests, and other health-related behaviors as assessed on the WHI baseline questionnaire.</p><p><strong>Results: </strong>Although of higher socioeconomic status than the heterosexuals, the lesbian and bisexual women more often used alcohol and cigarettes, exhibited other risk factors for reproductive cancers and cardiovascular disease, and scored lower on measures of mental health and social support. Notable is the 35% of lesbians and 81% of bisexual women who have been pregnant. Women reporting that they never had sex as an adult had lower rates of Papanicolaou screening and hormone replacement therapy use than other groups.</p><p><strong>Conclusions: </strong>This sample of older lesbian and bisexual women from WHI shows many of the same health behaviors, demographic, and psychosocial risk factors reported in the literature for their younger counterparts, despite their higher socioeconomic status and access to health care. The lower rates of recommended screening services and higher prevalence of obesity, smoking, alcohol use, and lower intake of fruit and vegetables among these women compared with heterosexual women indicate unmet needs that require effective interactions between care providers and nonheterosexual women.</p>","PeriodicalId":8295,"journal":{"name":"Archives of family medicine","volume":"9 9","pages":"843-53"},"PeriodicalIF":0.0,"publicationDate":"2000-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21862465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 399
The urgent need to improve hypertension care. 迫切需要改善高血压护理。
Pub Date : 2000-09-01 DOI: 10.1001/archfami.9.9.794
J S Trilling, J Froom

Hypertension is the most prevalent health problem among adult primary care patients, but its recognition and treatment are suboptimal. Although there is ample evidence from several large-scale randomized, controlled studies that treatment of hypertension reduces morbidity and mortality, current management of hypertension is characterized by underdiagnosis, misdiagnosis, undertreatment, overtreatment, and misuse of medications. As a result, roughly 75% of the estimated 50 million adults with hypertension in the United States are at increased risk for vascular complications. Optimal therapy requires careful attention to patients' age, sex, race, diet, exercise, tobacco use, comorbid conditions, choice of antihypertensive drug treatment, compliance with treatment, and achievement of blood pressure control. Other issues that deserve scrutiny are accuracy of the initial diagnosis, self-monitoring of blood pressure, and the advisability of attempting reduction of dosage or possible withdrawal from administration of antihypertensive drug treatment in patients whose blood pressures have been controlled for 1 year or more. Physicians' knowledge and use of the Sixth Joint National Committee on Prevention, Detection, and Treatment of High Blood Pressure report are deficient. Several responses to this current crisis in care of hypertensive patients are reviewed, including computer-aided management, medical chart audit, academic detailing, and a nurse case manager using prepared algorithms in consultation with the physician.

高血压是成人初级保健患者中最普遍的健康问题,但其认识和治疗是次优的。尽管一些大规模的随机对照研究有充分的证据表明,高血压治疗可以降低发病率和死亡率,但目前的高血压管理存在诊断不足、误诊、治疗不足、过度治疗和药物滥用的特点。因此,在美国估计的5000万成年高血压患者中,大约75%的人患血管并发症的风险增加。最佳治疗需要仔细考虑患者的年龄、性别、种族、饮食、运动、吸烟、合并症、抗高血压药物治疗的选择、治疗依从性和血压控制的实现。其他值得仔细检查的问题是初始诊断的准确性,血压的自我监测,以及血压控制1年或1年以上的患者尝试减少剂量或可能停药降压药的可行性。医生对第六届全国预防、检测和治疗高血压联合委员会报告的了解和使用不足。本文回顾了当前高血压患者护理危机的几种应对措施,包括计算机辅助管理、医疗图表审计、学术详细说明以及与医生协商使用准备好的算法的护士病例管理。
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引用次数: 85
Predictors of screening mammography: implications for office practice. 乳房x光筛查的预测因素:对办公室实践的影响。
Pub Date : 2000-09-01 DOI: 10.1001/archfami.9.9.870
D M Cummings, L Whetstone, A Shende, D Weismiller

Background: The completion of annual screening mammography and other preventive health services among women aged 50 years and older remains an important quality of care indicator.

Methods: A biracial sample of 843 rural women (aged > or =50 years) from a population-based sample reported demographic and preventive health services utilization in the last year including the completion of screening mammography. Bivariate analysis and logistic regression were used to investigate the extent to which completion of other screening examinations, including Papanicolaou (Pap) smears and clinical breast examination, is associated with successful completion of mammography relative to demographic and health service variables.

Results: The completion of mammography was associated with age, race, education, health insurance, and the presence of a regular primary care physician, but the strongest predictors were the completion of a clinical breast examination and/or a Pap smear.

Conclusions: Women who receive a clinical breast examination and/or a Pap smear appear far more likely to receive screening mammography, suggesting a synergy in screening services. The relative efficacy of interventions to increase the completion of clinical breast examinations as well as other age-appropriate preventive services during routine office visits or during a single preventive services office visit should be further explored in primary care settings. Residency programs should provide training on the successful incorporation of such services into office practice patterns in an effort to continually improve quality of care.

背景:在50岁及以上的妇女中完成年度乳房x光检查和其他预防性保健服务仍然是一个重要的护理质量指标。方法:以人口为基础的843名农村妇女(年龄>或=50岁)的混血人样本报告了去年人口统计学和预防性保健服务的利用情况,包括完成乳房x光筛查。使用双变量分析和逻辑回归来调查其他筛查检查(包括巴氏涂片检查和临床乳房检查)的完成程度与成功完成乳房x光检查(相对于人口统计学和卫生服务变量)的关系。结果:乳房x光检查的完成程度与年龄、种族、教育程度、健康保险和常规初级保健医生的存在有关,但最有力的预测因素是临床乳房检查和/或巴氏涂片检查的完成程度。结论:接受临床乳房检查和/或巴氏涂片检查的妇女似乎更有可能接受筛查性乳房x光检查,这表明筛查服务的协同作用。在初级保健机构中,应进一步探讨在常规办公室就诊期间或在单次预防服务办公室就诊期间提高临床乳房检查和其他适龄预防服务完成率的干预措施的相对有效性。住院医师项目应提供培训,使其成功地将此类服务纳入办公室实践模式,以不断提高护理质量。
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引用次数: 38
Traumatic life events in primary care patients: a study in an ethnically diverse sample. 初级保健病人的创伤性生活事件:一项不同种族样本的研究。
Pub Date : 2000-09-01 DOI: 10.1001/archfami.9.9.802
E A Holman, R C Silver, H Waitzkin

Objective: To examine among immigrants and others seeking primary care: (1) the prevalence, types, and predictors of traumatic life events; and (2) the relations among traumatic life events, psychiatric disorders, and utilization of primary care services.

Design: Survey with structured diagnostic interview.

Setting: Community-based, university-affiliated primary care clinic in southern California.

Participants: Fourteen hundred fifty-six adult patients representing 4 ethnic groups (Mexican immigrants, Central American immigrants, US-born Latinos of Mexican descent, and US-born non-Latino whites).

Dependent measures: Rates of traumatic events measured with the Posttraumatic Stress Disorder section of the Diagnostic Interview Schedule; psychiatric disorders identified by the Composite International Diagnostic Interview using Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition criteria; physical functioning (Short Form Health Survey); and the number of medical clinic visits during a 6-month period.

Results: Nearly 10% of patients had experienced a traumatic event in the previous year, and 57% had experienced at least 1 during their lifetimes. The most common forms of trauma were interpersonal violence occurring outside the family (21%), acute losses or accidents (17%), witnessing death or violence (13%), and domestic violence (12%). When compared with the US-born non-Latino whites, Mexican immigrants were half as likely, and Central American immigrants were 76% more likely, to report having experienced a traumatic event. Married individuals were significantly less likely to report traumas. Traumatic experiences, female gender, and non-Latino ethnicity were associated with the presence of a psychiatric disorder. One-year and lifetime psychiatric disorders were associated with poorer physical functioning and an increased number of clinic visits during a 6-month period.

Conclusions: Traumatic life events are common and associated with psychiatric disorders other than posttraumatic stress disorder in an ethnically diverse sample of primary care patients. Psychiatric disorders, in turn, are strongly associated with poor physical functioning and higher rates of primary care utilization. Screening for traumatic experiences should accompany assessments of psychiatric disorders to ensure adequate treatment of patients seeking primary care services.

目的:调查移民和其他寻求初级保健的人群:(1)创伤性生活事件的患病率、类型和预测因素;(2)创伤性生活事件、精神障碍与初级保健服务利用的关系。设计:采用结构化诊断访谈进行调查。环境:南加州以社区为基础的大学附属初级保健诊所。参与者:1456名成年患者,代表4个种族群体(墨西哥移民、中美洲移民、美国出生的墨西哥裔拉丁裔和美国出生的非拉丁裔白人)。依赖测量:创伤性事件发生率用诊断访谈表的创伤后应激障碍部分测量;使用《精神疾病诊断与统计手册》第三版修订版标准进行的综合国际诊断访谈确定的精神疾病;身体机能(简短健康调查);以及6个月内就诊的次数。结果:近10%的患者在前一年经历过创伤性事件,57%的患者在其一生中至少经历过一次。最常见的创伤形式是发生在家庭以外的人际暴力(21%)、严重损失或事故(17%)、目睹死亡或暴力(13%)和家庭暴力(12%)。与美国出生的非拉丁裔白人相比,墨西哥移民报告经历创伤性事件的可能性是墨西哥移民的一半,中美洲移民的可能性是76%。已婚人士报告创伤的可能性明显较低。创伤经历、女性性别和非拉丁裔与精神障碍的存在有关。一年和终身精神疾病与身体功能较差和6个月期间诊所就诊次数增加有关。结论:在不同种族的初级保健患者样本中,创伤性生活事件是常见的,并且与创伤后应激障碍以外的精神障碍有关。精神疾病反过来又与身体功能不良和初级保健使用率较高密切相关。对创伤经历的筛查应伴随对精神障碍的评估,以确保对寻求初级保健服务的患者进行适当治疗。
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引用次数: 149
Tamoxifen's clinical applications: old and new. 他莫昔芬的临床应用:新旧。
Pub Date : 2000-09-01 DOI: 10.1001/archfami.9.9.906
A U Buzdar

The American Cancer Society estimates that this year more than 180, 000 women in the United States will develop breast cancer and more than 40,000 women will die of the disease. According to a National Cancer Institute model, 5 years of preventive therapy with tamoxifen citrate reduced the risk of invasive breast cancer by 49% (P<.00001) in women at increased risk for breast cancer. The reduction in risk was greater in women with a history of lobular carcinoma in situ (LCIS; 56% relative risk reduction) or atypical hyperplasia (86% relative risk reduction). It should be noted, however, that no benefit was found in 2 European studies using notably different risk evaluation models and entry criteria. Because elevated risks of uterine cancer and thromboembolic disease have been associated with tamoxifen therapy, appropriate counseling should be given to any woman considering tamoxifen as a means of reducing breast cancer risk. Arch Fam Med. 2000;9:906-912

美国癌症协会估计,今年美国将有超过18万名女性患上乳腺癌,超过4万名女性将死于这种疾病。根据国家癌症研究所的模型,5年的柠檬酸他莫昔芬预防治疗使浸润性乳腺癌的风险降低了49% (P
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引用次数: 13
期刊
Archives of family medicine
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