Pub Date : 2026-02-01Epub Date: 2025-10-02DOI: 10.5546/aap.2025-10789
Jimena Fraga, Cecilia E Zubiri, Juan Varón, Silvia Del C Intruvini, Vanesa E Zaslavsky, Judith Cohen Sabban, Ana M Rocca, Guillermo P Alarcón, Karina A Leta, Horacio Bignón, Pablo E Aubone, Hernán Gaviño, Florencia Vans Landschoot
Gastrostomy (GTT) is a procedure that surgically or endoscopically connects the stomach to the outside of the abdomen, providing a long-term enteral feeding route. It is an essential nutritional alternative for children and adolescents with oral feeding difficulties, as it significantly improves their physical, psychological, and social quality of life, as well as that of their caregivers. This consensus has several key objectives: to identify children and adolescents who are candidates for this intervention, to describe the different types of procedures, to unify diagnostic criteria, to promote rational use of resources, to detail associated complications, to improve the quality of life of patients and their families and to foster interdisciplinary collaboration. To achieve this, a comprehensive review of the scientific literature was conducted, selecting the best available evidence to develop practical recommendations specific to pediatricians and adaptable to the local context.
{"title":"Consensus on gastrostomies in pediatrics: a multidisciplinary approach.","authors":"Jimena Fraga, Cecilia E Zubiri, Juan Varón, Silvia Del C Intruvini, Vanesa E Zaslavsky, Judith Cohen Sabban, Ana M Rocca, Guillermo P Alarcón, Karina A Leta, Horacio Bignón, Pablo E Aubone, Hernán Gaviño, Florencia Vans Landschoot","doi":"10.5546/aap.2025-10789","DOIUrl":"10.5546/aap.2025-10789","url":null,"abstract":"<p><p>Gastrostomy (GTT) is a procedure that surgically or endoscopically connects the stomach to the outside of the abdomen, providing a long-term enteral feeding route. It is an essential nutritional alternative for children and adolescents with oral feeding difficulties, as it significantly improves their physical, psychological, and social quality of life, as well as that of their caregivers. This consensus has several key objectives: to identify children and adolescents who are candidates for this intervention, to describe the different types of procedures, to unify diagnostic criteria, to promote rational use of resources, to detail associated complications, to improve the quality of life of patients and their families and to foster interdisciplinary collaboration. To achieve this, a comprehensive review of the scientific literature was conducted, selecting the best available evidence to develop practical recommendations specific to pediatricians and adaptable to the local context.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510789"},"PeriodicalIF":0.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2025-08-14DOI: 10.5546/aap.2025-10708.eng
Ana Feller, Mariana Aziz, Silvia Gil, Daniela Fortunati, Marianela Viso, María de Los Ángeles Insúa Beverina, Natalia Bermejo, Ianina Soria, Adriana Rosé, Marta Ciaccio, Gisela Viterbo
Denosumab has been shown to improve post-surgical morbidity in resectable lytic bone neoplasms with high RANK-L expression and to halt disease progression in unresectable cases. Intra- and post-treatment adverse effects have been reported. We conducted a prospective, descriptive study including six patients with lytic bone neoplasms treated with denosumab. The median age at onset treatment was 7.4 years, and the male-to-female ratio was 5:1. Five patients showed a favorable response. All patients developed hypocalcemia and hypophosphatemia during treatment, requiring adjustments in calcium and ergocalciferol/cholecalciferol supplementation (6/6), the addition of calcitriol (5/6), and phosphate salts (3/6). Metaphyseal bands were observed in 4 out of 6 patients. No fractures were reported, and most patients did not show evidence of impaired growth. Four patients experienced post-treatment hypercalcemia. Risk factors included younger age, a higher number of doses, and the presence of metaphyseal bands.
{"title":"Experience with denosumab in the treatment of bone diseases in pediatrics at a tertiary care hospital.","authors":"Ana Feller, Mariana Aziz, Silvia Gil, Daniela Fortunati, Marianela Viso, María de Los Ángeles Insúa Beverina, Natalia Bermejo, Ianina Soria, Adriana Rosé, Marta Ciaccio, Gisela Viterbo","doi":"10.5546/aap.2025-10708.eng","DOIUrl":"10.5546/aap.2025-10708.eng","url":null,"abstract":"<p><p>Denosumab has been shown to improve post-surgical morbidity in resectable lytic bone neoplasms with high RANK-L expression and to halt disease progression in unresectable cases. Intra- and post-treatment adverse effects have been reported. We conducted a prospective, descriptive study including six patients with lytic bone neoplasms treated with denosumab. The median age at onset treatment was 7.4 years, and the male-to-female ratio was 5:1. Five patients showed a favorable response. All patients developed hypocalcemia and hypophosphatemia during treatment, requiring adjustments in calcium and ergocalciferol/cholecalciferol supplementation (6/6), the addition of calcitriol (5/6), and phosphate salts (3/6). Metaphyseal bands were observed in 4 out of 6 patients. No fractures were reported, and most patients did not show evidence of impaired growth. Four patients experienced post-treatment hypercalcemia. Risk factors included younger age, a higher number of doses, and the presence of metaphyseal bands.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510708"},"PeriodicalIF":0.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2025-05-22DOI: 10.5546/aap.2025-10742.eng
Norma E Rossato, Néstor E Vain
{"title":"Impact of meconium-stained amniotic fluid from birth to childhood: Adverse or protective effects?","authors":"Norma E Rossato, Néstor E Vain","doi":"10.5546/aap.2025-10742.eng","DOIUrl":"10.5546/aap.2025-10742.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510742"},"PeriodicalIF":0.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2025-10-09DOI: 10.5546/aap.2025-10771.eng
Zeynep G Ergün Özdel, Güven Özkaya, Şenay Türe
Background: This study aims to determine parents' cyberchondria and health literacy levels and examine how these levels affect parents' behaviors regarding their own and their children's health. Method: This descriptive cross-sectional study was conducted between January 1, 2023, and June 30, 2023. Survey forms were used, and the surveys were filled out face to face. Results: 619 parents participated in the study. The parents' Cyberchondria Severity Scale (CSS) score was 71.51±22.46 (medium-high), and the Turkish Health Literacy Scale (THLS-32) score was 21.37±6.60 (insufficient); 92.2% of the parents stated that they diagnosed themselves and 91.1% of their children via the Internet, 14.2% of parents and 12% of their children stopped taking their medication due to information they read on the Internet. Conclusion: Parental internet use for health purposes is very high. Inadequate health literacy and high levels of cyberchondria increase the risk of making wrong health decisions. Health professionals should prioritize efforts to increase parents' health literacy and reduce the severity of cyberchondria.
{"title":"Parental health information seeking online: How cyberchondria and health literacy shape pediatric health decisions.","authors":"Zeynep G Ergün Özdel, Güven Özkaya, Şenay Türe","doi":"10.5546/aap.2025-10771.eng","DOIUrl":"10.5546/aap.2025-10771.eng","url":null,"abstract":"<p><p>Background: This study aims to determine parents' cyberchondria and health literacy levels and examine how these levels affect parents' behaviors regarding their own and their children's health. Method: This descriptive cross-sectional study was conducted between January 1, 2023, and June 30, 2023. Survey forms were used, and the surveys were filled out face to face. Results: 619 parents participated in the study. The parents' Cyberchondria Severity Scale (CSS) score was 71.51±22.46 (medium-high), and the Turkish Health Literacy Scale (THLS-32) score was 21.37±6.60 (insufficient); 92.2% of the parents stated that they diagnosed themselves and 91.1% of their children via the Internet, 14.2% of parents and 12% of their children stopped taking their medication due to information they read on the Internet. Conclusion: Parental internet use for health purposes is very high. Inadequate health literacy and high levels of cyberchondria increase the risk of making wrong health decisions. Health professionals should prioritize efforts to increase parents' health literacy and reduce the severity of cyberchondria.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510771"},"PeriodicalIF":0.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145237820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Langerhans cell histiocytosis is a rare disease characterized by the accumulation of Langerhans cells, which are myeloid dendritic cells, associated with significant inflammation and varied systemic involvement. Gastrointestinal involvement is rare, preceded in more than 80% of cases by skin lesions. We report the case of a 5-month-old girl whose clinical presentation was skin lesions and proctorrhagia. A transdisciplinary approach allowed us to reach a diagnosis and initiate timely treatment.
{"title":"Multisystem Langerhans cell histiocytosis with gastrointestinal involvement in an infant: A case report.","authors":"Kerly Fiestas, Wilma Geraige, Mariana Torres, Paula Roitman, Karina Arco, Giuliana Vaquer","doi":"10.5546/aap.2025-10752.eng","DOIUrl":"10.5546/aap.2025-10752.eng","url":null,"abstract":"<p><p>Langerhans cell histiocytosis is a rare disease characterized by the accumulation of Langerhans cells, which are myeloid dendritic cells, associated with significant inflammation and varied systemic involvement. Gastrointestinal involvement is rare, preceded in more than 80% of cases by skin lesions. We report the case of a 5-month-old girl whose clinical presentation was skin lesions and proctorrhagia. A transdisciplinary approach allowed us to reach a diagnosis and initiate timely treatment.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510752"},"PeriodicalIF":0.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144783358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2025-09-18DOI: 10.5546/aap.2025-10755.eng
Diana Kabbache, Natalia V Ratti, Silvina Tasat, Gabriel Vinderola
Breastfeeding is the gold standard in pediatric nutrition. When it is not possible, desired, or sufficient, infant formulas and foods for specific medical purposes are available, developed to meet special nutritional requirements. These products are manufactured using complex technological processes, under strict quality, hygiene, safety, and international regulations. Unlike other mass-market products (cookies, snacks), they are designed to contribute to children's nutrition. Their formulation includes adaptations in proteins, lipids, carbohydrates, vitamins, and minerals, according to the infant's needs.They are recommended in cases of prematurity, allergies, intolerances, digestive or metabolic disorders, or special conditions, and should always be recommended by a healthcare professional. Their correct use ensures the nutrients necessary for proper growth and development, as well as those essential for dietary and nutritional therapy.
{"title":"Processes applied to the manufacture of infant formulas and foods for special medical purposes.","authors":"Diana Kabbache, Natalia V Ratti, Silvina Tasat, Gabriel Vinderola","doi":"10.5546/aap.2025-10755.eng","DOIUrl":"10.5546/aap.2025-10755.eng","url":null,"abstract":"<p><p>Breastfeeding is the gold standard in pediatric nutrition. When it is not possible, desired, or sufficient, infant formulas and foods for specific medical purposes are available, developed to meet special nutritional requirements. These products are manufactured using complex technological processes, under strict quality, hygiene, safety, and international regulations. Unlike other mass-market products (cookies, snacks), they are designed to contribute to children's nutrition. Their formulation includes adaptations in proteins, lipids, carbohydrates, vitamins, and minerals, according to the infant's needs.They are recommended in cases of prematurity, allergies, intolerances, digestive or metabolic disorders, or special conditions, and should always be recommended by a healthcare professional. Their correct use ensures the nutrients necessary for proper growth and development, as well as those essential for dietary and nutritional therapy.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510755"},"PeriodicalIF":0.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2025-11-13DOI: 10.5546/aap.2025-10738.eng
Mariana J Cyunel, Sabina I Ramos Elizagaray, Ricardo J Ponce, César E Santini, Mariela I Subirá
Introduction. Advances in medicine have made organ and tissue transplantation a feasible therapeutic option. However, the shortage of pediatric donors leads to deaths among children on the organ waiting list in Argentina. The objective of this study was to identify variables related to the donation process that may offer opportunities to improve the pediatric donation rate. Population and methods. This was a retrospective observational study conducted in five institutions. Data were obtained from the medical records of patients aged 0 to 18 years who met the clinical criteria for death based on neurological criteria (DNC) in pediatric intensive care units (PICUs), emergency departments, and cardiovascular intensive care units between January 1, 2018, and December 31, 2022. Results. Among the participating centers, three were pediatric and two were general hospitals. A total of 124 patients with clinical DNC were included (1.3% of PICU admissions, 23% of deaths). Of these, 21 (17%) were donors. An 83% rate of missed donation opportunities was identified; the main areas for improvement were detection, diagnosis, and evaluation. Conclusion. DNC is an uncommon condition in pediatrics. This study identifies key areas for action to optimize the evaluation, detection, and management of potential donors-necessary steps to reduce deaths among children on transplant waiting lists.
{"title":"Pediatric organ donation: retrospective study in five centers in Argentina.","authors":"Mariana J Cyunel, Sabina I Ramos Elizagaray, Ricardo J Ponce, César E Santini, Mariela I Subirá","doi":"10.5546/aap.2025-10738.eng","DOIUrl":"10.5546/aap.2025-10738.eng","url":null,"abstract":"<p><p>Introduction. Advances in medicine have made organ and tissue transplantation a feasible therapeutic option. However, the shortage of pediatric donors leads to deaths among children on the organ waiting list in Argentina. The objective of this study was to identify variables related to the donation process that may offer opportunities to improve the pediatric donation rate. Population and methods. This was a retrospective observational study conducted in five institutions. Data were obtained from the medical records of patients aged 0 to 18 years who met the clinical criteria for death based on neurological criteria (DNC) in pediatric intensive care units (PICUs), emergency departments, and cardiovascular intensive care units between January 1, 2018, and December 31, 2022. Results. Among the participating centers, three were pediatric and two were general hospitals. A total of 124 patients with clinical DNC were included (1.3% of PICU admissions, 23% of deaths). Of these, 21 (17%) were donors. An 83% rate of missed donation opportunities was identified; the main areas for improvement were detection, diagnosis, and evaluation. Conclusion. DNC is an uncommon condition in pediatrics. This study identifies key areas for action to optimize the evaluation, detection, and management of potential donors-necessary steps to reduce deaths among children on transplant waiting lists.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510738"},"PeriodicalIF":0.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145487464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-29DOI: 10.5546/aap.2025-10990.eng
Gustavo H Marín, Anahí Álvarez Rotondo
{"title":"The current dengue vaccine landscape, with a focus on TAK-003 (Qdenga®).","authors":"Gustavo H Marín, Anahí Álvarez Rotondo","doi":"10.5546/aap.2025-10990.eng","DOIUrl":"https://doi.org/10.5546/aap.2025-10990.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510990"},"PeriodicalIF":0.5,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-22DOI: 10.5546/aap.2025-10796.eng
Carlos Giuseppucci, Ramiro Ortiz, Luciano Korman, María S Canestrari, Juliana Lostra, María C Castro Coria, Daniela Quirós, Camila Marossero, Luciana Cotignola, Verónica Giubergia
Esophageal lung is an extremely rare congenital malformation characterized by an abnormal connection between the esophagus and the bronchial tree, without communication with the airway. We present the case of a 4-month-old female patient who was admitted to the hospital with a diagnosis of pneumonia. Complementary studies confirmed the presumptive diagnosis of esophageal lung. Surgical treatment was then decided upon, and a pneumonectomy with esophageal repair was performed. The patient progressed favorably.
{"title":"Esophageal lung in a 4-month-old infant.","authors":"Carlos Giuseppucci, Ramiro Ortiz, Luciano Korman, María S Canestrari, Juliana Lostra, María C Castro Coria, Daniela Quirós, Camila Marossero, Luciana Cotignola, Verónica Giubergia","doi":"10.5546/aap.2025-10796.eng","DOIUrl":"https://doi.org/10.5546/aap.2025-10796.eng","url":null,"abstract":"<p><p>Esophageal lung is an extremely rare congenital malformation characterized by an abnormal connection between the esophagus and the bronchial tree, without communication with the airway. We present the case of a 4-month-old female patient who was admitted to the hospital with a diagnosis of pneumonia. Complementary studies confirmed the presumptive diagnosis of esophageal lung. Surgical treatment was then decided upon, and a pneumonectomy with esophageal repair was performed. The patient progressed favorably.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510796"},"PeriodicalIF":0.5,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-22DOI: 10.5546/aap.2025-10805.eng
Natalia L Pugliese, Patricia I Tabacco, María Del C Campos
Medical and technological advances have increased the survival rate of children with congenital heart disease, which has led to a deeper understanding of various aspects of their subsequent development. Cardiovascular involvement has a direct impact on feeding, causing sucking and swallowing dysfunctions from birth that can trigger a series of consequences such as malnutrition, dysphagia, and clinical discomfort. This problem not only affects the physiological sphere but also the emotional and family dimensions. This article summarizes key findings in the growing literature on the impact of heart disease on pediatric nutrition and emphasizes the role of speech-language pathology. Further research on this issue is needed to provide greater knowledge that improves the quality of life of these children and their families.
{"title":"Feeding disorders in children with congenital heart disease: clinical implications and the role of the speech and language pathologist.","authors":"Natalia L Pugliese, Patricia I Tabacco, María Del C Campos","doi":"10.5546/aap.2025-10805.eng","DOIUrl":"https://doi.org/10.5546/aap.2025-10805.eng","url":null,"abstract":"<p><p>Medical and technological advances have increased the survival rate of children with congenital heart disease, which has led to a deeper understanding of various aspects of their subsequent development. Cardiovascular involvement has a direct impact on feeding, causing sucking and swallowing dysfunctions from birth that can trigger a series of consequences such as malnutrition, dysphagia, and clinical discomfort. This problem not only affects the physiological sphere but also the emotional and family dimensions. This article summarizes key findings in the growing literature on the impact of heart disease on pediatric nutrition and emphasizes the role of speech-language pathology. Further research on this issue is needed to provide greater knowledge that improves the quality of life of these children and their families.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510805"},"PeriodicalIF":0.5,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}