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Inside edge - prevalence and factors associated with symptoms of anxiety/depression in professional cricketers. 内线--职业板球运动员焦虑/抑郁症状的发生率和相关因素。
IF 2.4 Pub Date : 2024-05-01 Epub Date: 2022-10-25 DOI: 10.1080/15438627.2022.2139619
Sharief Hendricks, Nur Amino, J P van Wyk, Vincent Gouttenbarge, Stephen Mellalieu, Ruan Schlebusch

The purpose of this study was to i) determine the prevalence of anxiety/depression symptoms in professional cricketers and ii) identify factors associated with symptoms of anxiety/depression. One-hundred and seventy-seven (n = 177, response rate of 76%) professional cricketers completed the General Health Questionnaire 12 (GHQ-12). Odd ratios (OR) for anxiety/depression symptoms were related to players' career, family and education. Prevalence of symptoms of anxiety/depression was 59% (n = 104/177). Anxiety/depression symptoms increased when players were contracted for more than 2 years (OR: 5.0; 95% CI: 1.2-21.3; p = 0.028) and if they played their last offseason overseas (OR: 3.5; 95% CI: 1.3-9.6; p = 0.013). Anxiety/depression symptoms decreased by 70% when players made "productive use" of their time in the offseason (OR: 0.3; 95% CI: 0.1-0.9; p = 0.036) and contracted for 2 years (OR: 0.3; 95% CI: 0.1-1.0; p = 0.049). These findings can be incorporated into cricket mental health literacy programmes to improve awareness and understanding, and to encourage early help-seeking.

本研究的目的是 i) 确定职业板球运动员焦虑/抑郁症状的发生率;ii) 找出与焦虑/抑郁症状相关的因素。177 名(n = 177,回复率为 76%)职业板球运动员填写了《一般健康问卷 12》(GHQ-12)。焦虑/抑郁症状的奇数比(OR)与球员的职业、家庭和教育有关。焦虑/抑郁症状的患病率为 59%(n = 104/177)。如果球员的合同期超过 2 年(OR:5.0;95% CI:1.2-21.3;p = 0.028),并且最后一个季后赛是在海外进行(OR:3.5;95% CI:1.3-9.6;p = 0.013),焦虑/抑郁症状就会增加。当球员 "有效利用 "休赛期时间(OR:0.3;95% CI:0.1-0.9;p = 0.036)和签约 2 年(OR:0.3;95% CI:0.1-1.0;p = 0.049)时,焦虑/抑郁症状会减少 70%。这些发现可以被纳入板球心理健康扫盲计划,以提高人们对板球的认识和理解,并鼓励人们及早寻求帮助。
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引用次数: 0
Exosomal mitochondrial tRNAs and miRNAs as potential predictors of inflammation in renal proximal tubular epithelial cells. 外泌体线粒体 tRNA 和 miRNA 作为肾近曲小管上皮细胞炎症的潜在预测因子。
IF 6.5 Pub Date : 2022-05-04 eCollection Date: 2022-06-14 DOI: 10.1016/j.omtn.2022.04.035
Glory Ranches, Maximilian Zeidler, Roman Kessler, Martina Hoelzl, Michael W Hess, Jonathan Vosper, Paul Perco, Herbert Schramek, Kai K Kummer, Michaela Kress, Anne Krogsdam, Michael Rudnicki, Gert Mayer, Alexander Huettenhofer

Exosomes have emerged as a valuable repository of novel biomarkers for human diseases such as chronic kidney disease (CKD). From a healthy control group, we performed microRNA (miRNA) profiling of urinary exosomes and compared it with a cell culture model of renal proximal tubular epithelial cells (RPTECs). Thereby, a large fraction of abundant urinary exosomal miRNAs could also be detected in exosomes derived from RPTECs, indicating them as a suitable model system for investigation of CKD. We subsequently analyzed exosomes from RPTECs in pro-inflammatory and pro-fibrotic states, mimicking some aspects of CKD. Following cytokine treatment, we observed a significant increase in exosome release and identified 30 dysregulated exosomal miRNAs, predominantly associated with the regulation of pro-inflammatory and pro-fibrotic-related pathways. In addition to miRNAs, we also identified 16 dysregulated exosomal mitochondrial RNAs, highlighting a pivotal role of mitochondria in sensing renal inflammation. Inhibitors of exosome biogenesis and release significantly altered the abundance of selected candidate miRNAs and mitochondrial RNAs, thus suggesting distinct sorting mechanisms of different non-coding RNA (ncRNA) species into exosomes. Hence, these two exosomal ncRNA species might be employed as potential indicators for predicting the pathogenesis of CKD and also might enable effective monitoring of the efficacy of CKD treatment.

外泌体已成为慢性肾脏病(CKD)等人类疾病的新型生物标记物的宝贵宝库。我们对健康对照组的尿液外泌体进行了微RNA(miRNA)分析,并与肾近曲小管上皮细胞(RPTECs)的细胞培养模型进行了比较。结果表明,在 RPTECs 的外泌体中也能检测到大量的尿液外泌体 miRNA,这表明它们是研究 CKD 的合适模型系统。随后,我们模拟 CKD 的某些方面,分析了促炎和促纤维化状态下 RPTECs 的外泌体。经细胞因子处理后,我们观察到外泌体释放量显著增加,并鉴定出了30种调控失调的外泌体miRNA,这些miRNA主要与促炎症和促纤维化相关通路的调控有关。除了 miRNAs 外,我们还发现了 16 种调控失调的外泌体线粒体 RNAs,突显了线粒体在感知肾脏炎症中的关键作用。外泌体生物生成和释放抑制剂显著改变了所选候选miRNA和线粒体RNA的丰度,从而表明不同的非编码RNA(ncRNA)物种进入外泌体的分拣机制各不相同。因此,这两种外泌体ncRNA可作为预测CKD发病机制的潜在指标,也可有效监测CKD的治疗效果。
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引用次数: 0
Prevalence of Toxocara species in park soils of Ahvaz City, southwest of Iran 伊朗西南部阿瓦士市公园土壤中弓形虫种类的流行
Pub Date : 2017-11-27 DOI: 10.12980/APJTD.7.2017D7-173
F. Kazemi, R. Arjmand, M. Tavalla
Prevalence of Toxocara species in park soils of Ahvaz City, southwest of Iran Forough Kazemi, Reza Arjmand, Mehdi Tavalla Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Department of Parasitology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Golestan Hospital Clinical Research Development Unit, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Asian Pac J Trop Dis 2017; 7(12): 705-707
Forough Kazemi, Reza Arjmand, Mehdi Tavalla学生研究委员会,Ahvaz Jundishapur医科大学,Ahvaz医学院寄生虫学系,Ahvaz伊朗Golestan医院临床研究开发部,Ahvaz Jundishapur医科大学,Ahvaz伊朗卫生研究所,Ahvaz伊朗阿瓦士Jundishapur医科大学感染性和热带病研究中心,阿瓦士,伊朗。7 (12): 705 - 707
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引用次数: 2
Determine the prevalence of intestinal and soil-transmitted helminths using different copromicroscopic techniques in Krabi Province, Thailand 在泰国甲米省使用不同的共显微技术确定肠道和土壤传播蠕虫的流行情况
Pub Date : 2017-11-27 DOI: 10.12980/APJTD.7.2017D7-196
S. Kitvatanachai, Aree Taylor, Pochong Rhongbutsri, W. Pongstaporn
Sirima Kitvatanachai, Aree Taylor, Pochong Rhongbutsri, Wanida Pongstaporn Faculty of Medical Technology, Rangsit University, Pathumthani, 12000, Thailand Department of Preclinical Science, Faculty of Medicine, Thammasat University, Pathumthani, 12120, Thailand Department of Biomedical Science, Faculty of Science, Rangsit University, Pathumthani, 12000, Thailand Asian Pac J Trop Dis 2017; 7(12): 719-723
Sirima Kitvatanachai,Aree Taylor,Pochong Rhongbutsri,Wanida Pongstaporn医学技术学院,朗西特大学,Pathumthani,12000,泰国医学院临床前科学系,帕图姆萨尼,12120,朗西特大学,泰国生物医学科学系,科学院,帕图姆萨尼,12000,2017年泰国亚洲太平洋医学奖;7(12):719-723
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引用次数: 3
Isolation and genetic detection of pathogenic Leptospira spp. from environmental soils and water in Central Luzon, Philippines 菲律宾吕宋岛中部环境土壤和水体致病性钩端螺旋体的分离与遗传检测
Pub Date : 2017-11-27 DOI: 10.12980/APJTD.7.2017D7-220
Ourlad Alzeus G. Tantengco, N. Gloriani
*Corresponding author: Nina Gonzales Gloriani, MD, PhD, Department of Medical Microbiology, College of Public Health, University of the Philippines Manila, Pedro Gil Street, Ermita, Manila, Philipppines. Tel: +632 525 5874 Fax: +632 521 1394 E-mail: nggloriani@up.edu.ph The journal implements double-blind peer review practiced by specially invited international editorial board members.
*通讯作者:Nina Gonzales Gloriani,医学博士,菲律宾马尼拉大学公共卫生学院医学微生物学系,Pedro Gil Street, Ermita, Manila, Philippines。电话:+632 525 5874传真:+632 521 1394 E-mail: nggloriani@up.edu.ph特邀国际编委会成员进行双盲同行评议。
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引用次数: 1
A fatal case of imported malaria in a non-endemic developing country – Mongolia, 2016 2016年在一个非流行发展中国家——蒙古发生的输入性疟疾致命病例
Pub Date : 2017-11-27 DOI: 10.12980/apjtd.7.2017D7-216
M. E. Fricken, Bekhochir Baigalmaa, Ganbold Dalantai, L. Valenzuela, N. Tsogbadrakh, Julia E. Painter, P. Lantos
Michael Emery von Fricken, Bekh-Ochir Baigalmaa, Ganbold Dalantai, Leslie Valenzuela, Nymadorj Tsogbadrakh, Julia Ellenberg Painter, Paul Michael Lantos Department of Global and Community Health, George Mason University, Fairfax, VA, USA National Center for Zoonotic Diseases, Ministry of Health, Ulaanbaatar, Mongolia Division of Pediatric Infectious Diseases, School of Medicine, Duke University, Durham, NC, USA Division of General Internal Medicine, School of Medicine, Duke University, Durham, NC, USA Duke Global Health Institute, Duke University, Durham, NC, USA Asian Pac J Trop Dis 2017; 7(12): 815-816
Michael Emery von Fricken、Bekh Ochir Baigalmaa、Ganbold Dalantai、Leslie Valenzuela、Nymadorj Tsogbadrakh、Julia Ellenberg Painter、Paul Michael Lantos乔治梅森大学全球和社区卫生系、弗吉尼亚州费尔法克斯、美国国家动物传染病中心、乌兰巴托卫生部、杜克大学医学院蒙古儿科传染病司,美国北卡罗来纳州达勒姆市杜克大学医学院普通内科,北卡罗来纳州达勒姆市,美国杜克大学全球健康研究所,北卡罗来纳大学达勒姆市,2017年美国亚洲太平洋医学会Trop Dis;7(12):815-816
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引用次数: 0
Antileishmanial activity of medicinal plants from Africa: A review 非洲药用植物的抗癫痫活性研究进展
Pub Date : 2017-11-27 DOI: 10.12980/APJTD.7.2017D7-215
A. Et-Touys, A. Bouyahya, H. Fellah, Meryem Mniouil, H. Boury, N. Dakka, A. Sadak, Y. Bakri
*Corresponding author: Abdelhakim Bouyahya, Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, and Genomic Center of Human Pathologies, Mohammed V University, Rabat 4, Av. Ibn battouta BP1014, Rabat, Morocco. Tel: +2126013508 E-mail: boyahyaa-90@hotmail.fr Peer review under responsibility of Hainan Medical University. The journal implements double-blind peer review practiced by specially invited international editorial board members.
*通讯作者:Abdelhakim Bouyahya,穆罕默德五世大学生物学系人类病理生物学实验室和人类病理基因组中心,Rabat 4, Av. Ibn battouta BP1014, Rabat,摩洛哥。联系电话:+2126013508 E-mail: boyahyaa-90@hotmail.fr海南医科大学负责同行评议。本刊实行双盲同行评议,特邀国际编委会成员参与。
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引用次数: 7
Zika virus disease expansion rate: The analysis from the first detection in Thailand 寨卡病毒疾病扩展率:从泰国首次检测结果分析
Pub Date : 2017-11-27 DOI: 10.12980/apjtd.7.2017D7-204
S. Wiwanitkit, V. Wiwanitkit
Zika virus is a new problematic pathogen. The virus can cause acute febrile illness and can also induce unwanted teratogenic effect if it infects a pregnant subject. The outbreak of Zika virus infection is an important public health problem. Now it affects several countries around the world including those countries in tropical and non-tropical areas. The worldwide expansion of disease becomes a big health issue. In tropical area, the disease already exists and continuously expands[1]. The Zika virus infection is considered an acute denguelike illness. The disease might have the similar clinical presentations to dengue, but it can have unwanted clinical complications such as neurological disorder and teratogenic effect. The disease is widely distributed in several areas of the world at present and there is a need for disease control and management. To manage the case, early case detection and management is the basic principle. In preventive medicine, prevention of mosquito bite and safe sexual practice is generally recommended. At present, there is still no specific anitviral drug or vaccine against Zika virus for disease treatment or prophylaxis. In epidemiology, a close disease monitoring is required. The data from disease surveillance can be useful in public health and the surveillance is generally recommended for any countries. Implementation of a good surveillance system is the basic requirement. Nevertheless, how to make use of the derived surveillance data is the topic that should be discussed. At present, surveillance of Zika virus infection is done in many countries around the world but the further use of the collected data is extremely limited. There is still no specific report assessing the expansion rate of disease in affected county. Here, the authors studied on Zika virus disease expansion rate based on the analysis from ARTICLE INFO ABSTRACT
寨卡病毒是一种新的问题病原体。该病毒可引起急性发热性疾病,如果感染孕妇,也可引起不必要的致畸作用。寨卡病毒感染的爆发是一个重要的公共卫生问题。现在它影响了世界上几个国家,包括热带和非热带地区的国家。疾病在世界范围内的蔓延已成为一个重大的健康问题。在热带地区,该病已经存在并不断扩大。寨卡病毒感染被认为是一种急性登革热样疾病。该病可能具有与登革热相似的临床表现,但它可能具有不必要的临床并发症,如神经紊乱和致畸作用。目前该病在世界若干地区广泛分布,需要进行疾病控制和管理。对病例进行管理,早发现、早管理是基本原则。在预防医学中,一般建议预防蚊虫叮咬和安全的性行为。目前,仍没有针对寨卡病毒的特异性抗病毒药物或疫苗用于疾病的治疗或预防。在流行病学中,需要进行密切的疾病监测。疾病监测数据可用于公共卫生,一般建议对任何国家进行监测。实施良好的监测制度是基本要求。然而,如何利用衍生的监测数据是应该讨论的话题。目前,世界上许多国家都对寨卡病毒感染进行了监测,但收集到的数据的进一步利用极为有限。目前还没有具体的报告评估受影响县的疾病扩展率。本文在文章分析的基础上,对寨卡病毒疾病扩展率进行了研究
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引用次数: 0
Molecular characterization of Coxiella burnetii in the slaughtered animals of Southern Iran 伊朗南部屠宰动物伯纳氏科希氏菌分子特征分析
Pub Date : 2017-11-27 DOI: 10.12980/APJTD.7.2017D7-194
S. Hosseinzadeh, A. Oryan, S. K. Limaki, A. Moaddeli, M. Poormontaseri, Vahideh Taghadosi
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引用次数: 1
Evaluation on the bioefficacy of PermaNet® 2.0, a long lasting net against Anopheles stephensi 长效防按蚊蚊帐PermaNet®2.0生物功效评价
Pub Date : 2017-11-27 DOI: 10.12980/APJTD.7.2017D6-368
A. Bagheri, H. Vatandoost, M. Shayeghi, M. Abai, A. Raeisi, Nutifafa Gidiglo Godwin, M. Akbari, Soraya Sheikhi
*Corresponding author: Hassan Vatandoost, Department of Medical Entomology & Vector Control, School of Public Health & National Institute of Health Research, Tehran University of Medical Sciences, Tehran, Iran. Tel: +982188954441 E-mails: hvatandoost1@yahoo.com, vatando@tums.ac.ir Foundation Project: Funded by Tehran University of Medical Sciences under code number of 09211263003. The journal implements double-blind peer review practiced by specially invited international editorial board members.
*通讯作者:Hassan Vatandoost,伊朗德黑兰医科大学公共卫生学院和国家卫生研究所医学昆虫学与病媒控制系。联系电话:+982188954441电子邮件:hvatandoost1@yahoo.com, vatando@tums.ac.ir基金项目:德黑兰医科大学资助,项目代码:09211263003。本刊实行双盲同行评议,特邀国际编委会成员参与。
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引用次数: 5
期刊
Asian Pacific Journal of Tropical Disease
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