Raneen Sawaid Kaiyal, Darren J. Bryk, Shinnosuke Kuroda, Johnathan Doolittle, Neel V. Parekh, Edmund Sabanegh, Nina Desai, Scott D. Lundy, Sarah C. Vij
IntroductionMicrosurgical testicular sperm extraction (microTESE) is crucial for treating non‐obstructive azoospermia (NOA), offering both ‘fresh’ and ‘frozen’ options. This study evaluates the impact of fresh versus frozen microTESE on the progression to intra‐cytoplasmic sperm injection (ICSI) cycles, focusing on sperm motility.Materials and MethodsWe conducted a retrospective analysis of microTESE procedures at a major medical centre from 2007 to 2021, excluding cases of obstructive azoospermia and cryptozoospermia. Patients were divided into two groups: fresh microTESE (Group FR) and frozen microTESE (Group FZ). Sperm motility was assessed, and ICSI outcomes were compared between groups.ResultsOut of 128 microTESE procedures on 113 NOA patients, 31 were fresh and 97 were frozen. Sperm was found in 67.7% of fresh cases and 45.3% of frozen cases. In fresh cases, 85.7% had motile sperm for ICSI, whereas in frozen cases, 81.8% had motile sperm initially, but only 52.7% retained motility post‐thaw.ConclusionsOur findings indicate a significant drop in motile sperm availability for ICSI in frozen microTESE cases compared to fresh ones. This suggests a potential advantage of fresh microTESE for certain couples, despite the logistical challenges, highlighting the need for careful patient selection and counselling.
{"title":"Comparative motility assessment of sperm retrieved from micro‐testicular sperm extraction: A single‐centre study comparing fresh and frozen–thawed sperm","authors":"Raneen Sawaid Kaiyal, Darren J. Bryk, Shinnosuke Kuroda, Johnathan Doolittle, Neel V. Parekh, Edmund Sabanegh, Nina Desai, Scott D. Lundy, Sarah C. Vij","doi":"10.1111/ajo.13880","DOIUrl":"https://doi.org/10.1111/ajo.13880","url":null,"abstract":"IntroductionMicrosurgical testicular sperm extraction (microTESE) is crucial for treating non‐obstructive azoospermia (NOA), offering both ‘fresh’ and ‘frozen’ options. This study evaluates the impact of fresh versus frozen microTESE on the progression to intra‐cytoplasmic sperm injection (ICSI) cycles, focusing on sperm motility.Materials and MethodsWe conducted a retrospective analysis of microTESE procedures at a major medical centre from 2007 to 2021, excluding cases of obstructive azoospermia and cryptozoospermia. Patients were divided into two groups: fresh microTESE (Group FR) and frozen microTESE (Group FZ). Sperm motility was assessed, and ICSI outcomes were compared between groups.ResultsOut of 128 microTESE procedures on 113 NOA patients, 31 were fresh and 97 were frozen. Sperm was found in 67.7% of fresh cases and 45.3% of frozen cases. In fresh cases, 85.7% had motile sperm for ICSI, whereas in frozen cases, 81.8% had motile sperm initially, but only 52.7% retained motility post‐thaw.ConclusionsOur findings indicate a significant drop in motile sperm availability for ICSI in frozen microTESE cases compared to fresh ones. This suggests a potential advantage of fresh microTESE for certain couples, despite the logistical challenges, highlighting the need for careful patient selection and counselling.","PeriodicalId":8599,"journal":{"name":"Australian and New Zealand Journal of Obstetrics and Gynaecology","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142256687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa Hui, Pema Hayman, Ali Buckland, Michael C Fahey, David A Mackey, Andrew J Mallett, Daniel R Schweitzer, Clare P Stuart, Wai Yan Yau, John Christodoulou
Mitochondrial donation to reduce the risk of primary mitochondrial disease transmission from mother to child is now permitted under Australian law as part of a clinical trial. The energy demands of pregnancy have the potential to worsen mitochondrial disease symptoms and severity in affected women. We conducted a systematic literature review on mitochondrial disease in pregnancy; five cohort studies and 19 case reports were included. For many women with mitochondrial disease, pregnancy does not have a negative effect on health status. However, serious adverse outcomes may occur. We provide suggested guidelines for preconception counselling and antenatal care.
{"title":"Pregnancy in women with mitochondrial disease—A literature review and suggested guidance for preconception and pregnancy care","authors":"Lisa Hui, Pema Hayman, Ali Buckland, Michael C Fahey, David A Mackey, Andrew J Mallett, Daniel R Schweitzer, Clare P Stuart, Wai Yan Yau, John Christodoulou","doi":"10.1111/ajo.13874","DOIUrl":"https://doi.org/10.1111/ajo.13874","url":null,"abstract":"Mitochondrial donation to reduce the risk of primary mitochondrial disease transmission from mother to child is now permitted under Australian law as part of a clinical trial. The energy demands of pregnancy have the potential to worsen mitochondrial disease symptoms and severity in affected women. We conducted a systematic literature review on mitochondrial disease in pregnancy; five cohort studies and 19 case reports were included. For many women with mitochondrial disease, pregnancy does not have a negative effect on health status. However, serious adverse outcomes may occur. We provide suggested guidelines for preconception counselling and antenatal care.","PeriodicalId":8599,"journal":{"name":"Australian and New Zealand Journal of Obstetrics and Gynaecology","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142222794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Journal Editorial Board","authors":"","doi":"10.1111/ajo.13564","DOIUrl":"https://doi.org/10.1111/ajo.13564","url":null,"abstract":"","PeriodicalId":8599,"journal":{"name":"Australian and New Zealand Journal of Obstetrics and Gynaecology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84059457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Journal Editorial Board","authors":"","doi":"10.1111/ajo.13388","DOIUrl":"https://doi.org/10.1111/ajo.13388","url":null,"abstract":"","PeriodicalId":8599,"journal":{"name":"Australian and New Zealand Journal of Obstetrics and Gynaecology","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85163714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The rupture of a splenic artery aneurysm (SAA) in pregnancy is a highly lethal condition, but so rare that most obstetricians would not encounter it during their career. In the seven official ‘Maternal Deaths in Australia’ reports, that covered 21 years from 1997 to 2017, among a total of 449 direct and indirect deaths, there were nine deaths (2%) from a ruptured SAA. These cases, and other cases from the literature and the Cochrane Library, are reviewed. The aim of the review is to raise awareness among clinicians of this potentially fatal condition.
{"title":"Maternal deaths in Australia from ruptured splenic artery aneurysms","authors":"G. Lawson","doi":"10.1111/ajo.13537","DOIUrl":"https://doi.org/10.1111/ajo.13537","url":null,"abstract":"The rupture of a splenic artery aneurysm (SAA) in pregnancy is a highly lethal condition, but so rare that most obstetricians would not encounter it during their career. In the seven official ‘Maternal Deaths in Australia’ reports, that covered 21 years from 1997 to 2017, among a total of 449 direct and indirect deaths, there were nine deaths (2%) from a ruptured SAA. These cases, and other cases from the literature and the Cochrane Library, are reviewed. The aim of the review is to raise awareness among clinicians of this potentially fatal condition.","PeriodicalId":8599,"journal":{"name":"Australian and New Zealand Journal of Obstetrics and Gynaecology","volume":"102 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80460332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. A. Rajadurai, E. Nathan, J. Pontré, B. Mcelhinney, K. Karthigasu, R. Hart
To test for the association between increasing patient body mass index (BMI) and the cost of total laparoscopic hysterectomy (TLH). Secondary outcomes include the relationship between increasing BMI and both peri‐ and post‐operative morbidity.
{"title":"The effect of obesity on cost of total laparoscopic hysterectomy","authors":"V. A. Rajadurai, E. Nathan, J. Pontré, B. Mcelhinney, K. Karthigasu, R. Hart","doi":"10.1111/ajo.13520","DOIUrl":"https://doi.org/10.1111/ajo.13520","url":null,"abstract":"To test for the association between increasing patient body mass index (BMI) and the cost of total laparoscopic hysterectomy (TLH). Secondary outcomes include the relationship between increasing BMI and both peri‐ and post‐operative morbidity.","PeriodicalId":8599,"journal":{"name":"Australian and New Zealand Journal of Obstetrics and Gynaecology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89678637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asthma in pregnancy has been shown in a number of studies to be associated with adverse perinatal outcomes including low birth weight and perinatal death.1– 4 However, the majority of studies in this area have been in general populations in the US, Europe and Australia. It is therefore of interest that Clifton et al.5 recently published a study on perinatal outcomes in an Australian Indigenous population, especially as adverse perinatal outcomes in this population remain high, (although declining), with mortality and low birth weight rates double that of nonIndigenous rates.6 However, I do have some concerns about the results presented and their interpretation, namely around the choices of control group and confounders. In the abstract and results section the authors have stated they observed a twofold increase in neonatal deaths in Indigenous babies whose mothers had asthma compared to nonIndigenous women who did not have asthma. However, in Table 2 where odds ratios of Indigenous women with asthma have been presented the reference group is referred to as being ‘nonIndigenous women without asthma’. Given the existing risk of adverse perinatal outcomes in the Australian Indigenous population it is therefore not possible to tell what role asthma plays in these findings or whether the reported associations are in fact driven by Indigenous status (or rather, the risk factors and behaviours as a results of colonisation and racism that continue to drive Indigenous health outcomes). Further, the findings in Table 2 that asthma does not show any added effect on perinatal outcomes in nonIndigenous women supports the argument, that at least in this dataset, asthma may not be making a difference on perinatal outcomes. The other possible source of confounding is socioeconomic status. The authors have stated that the inclusion of confounders was determined by the univariate associations between covariates and outcomes. Table 1 shows that socioeconomic status measured as attained education level was significantly different between Indigenous and nonIndigenous mothers, P < 0.001. Given these findings and that it is well recognised that socioeconomic determinants are a strong driver of health,7 it is unclear then why the multivariate associations were not adjusted for education level. Although no other similar studies exist for Indigenous groups, studies comparing Black, Hispanic and White American women found that although Black women had a higher prevalence of asthma and were more likely to have lower socioeconomic determinants, asthma was not able to explain the increase in adverse perinatal outcomes in Black populations.8 These authors concluded that asthma does not contribute to racial disparities in obstetric and neonatal complications. It is therefore my suspicion that the results from Clifton et al. are driven in large part by Indigenous status and socioeconomic differences rather than by asthma. It may be that asthma is an effect modifier of the impact
{"title":"Adverse perinatal outcomes in the Australian Indigenous population, the role of asthma","authors":"Bronwyn K Brew","doi":"10.1111/ajo.13468","DOIUrl":"https://doi.org/10.1111/ajo.13468","url":null,"abstract":"Asthma in pregnancy has been shown in a number of studies to be associated with adverse perinatal outcomes including low birth weight and perinatal death.1– 4 However, the majority of studies in this area have been in general populations in the US, Europe and Australia. It is therefore of interest that Clifton et al.5 recently published a study on perinatal outcomes in an Australian Indigenous population, especially as adverse perinatal outcomes in this population remain high, (although declining), with mortality and low birth weight rates double that of nonIndigenous rates.6 However, I do have some concerns about the results presented and their interpretation, namely around the choices of control group and confounders. In the abstract and results section the authors have stated they observed a twofold increase in neonatal deaths in Indigenous babies whose mothers had asthma compared to nonIndigenous women who did not have asthma. However, in Table 2 where odds ratios of Indigenous women with asthma have been presented the reference group is referred to as being ‘nonIndigenous women without asthma’. Given the existing risk of adverse perinatal outcomes in the Australian Indigenous population it is therefore not possible to tell what role asthma plays in these findings or whether the reported associations are in fact driven by Indigenous status (or rather, the risk factors and behaviours as a results of colonisation and racism that continue to drive Indigenous health outcomes). Further, the findings in Table 2 that asthma does not show any added effect on perinatal outcomes in nonIndigenous women supports the argument, that at least in this dataset, asthma may not be making a difference on perinatal outcomes. The other possible source of confounding is socioeconomic status. The authors have stated that the inclusion of confounders was determined by the univariate associations between covariates and outcomes. Table 1 shows that socioeconomic status measured as attained education level was significantly different between Indigenous and nonIndigenous mothers, P < 0.001. Given these findings and that it is well recognised that socioeconomic determinants are a strong driver of health,7 it is unclear then why the multivariate associations were not adjusted for education level. Although no other similar studies exist for Indigenous groups, studies comparing Black, Hispanic and White American women found that although Black women had a higher prevalence of asthma and were more likely to have lower socioeconomic determinants, asthma was not able to explain the increase in adverse perinatal outcomes in Black populations.8 These authors concluded that asthma does not contribute to racial disparities in obstetric and neonatal complications. It is therefore my suspicion that the results from Clifton et al. are driven in large part by Indigenous status and socioeconomic differences rather than by asthma. It may be that asthma is an effect modifier of the impact","PeriodicalId":8599,"journal":{"name":"Australian and New Zealand Journal of Obstetrics and Gynaecology","volume":"103 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74372046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katrina Calvert, S. Leathersich, P. Howat, Sarah Van Der Wal
‘Tomorrow belongs to those who can hear it coming’ David Bowie. Language is a living entity that moves and changes. Use of gender‐neutral language in medical literature is increasingly common. It is time for obstetricians and gynaecologists in Australia and New Zealand to interrogate their own bias and desire to maintain the status quo, and to consider reasons for change.
{"title":"Time to make some noise about a quiet revolution","authors":"Katrina Calvert, S. Leathersich, P. Howat, Sarah Van Der Wal","doi":"10.1111/ajo.13530","DOIUrl":"https://doi.org/10.1111/ajo.13530","url":null,"abstract":"‘Tomorrow belongs to those who can hear it coming’ David Bowie. Language is a living entity that moves and changes. Use of gender‐neutral language in medical literature is increasingly common. It is time for obstetricians and gynaecologists in Australia and New Zealand to interrogate their own bias and desire to maintain the status quo, and to consider reasons for change.","PeriodicalId":8599,"journal":{"name":"Australian and New Zealand Journal of Obstetrics and Gynaecology","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79212445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
6. Australian Institute of Health and Welfare & National Indigenous Australians Agency. Aboriginal and Torres Strait Islander Health Performance Framework; 2020. Available from URL: https://www. indig enous hpf.gov.au/. Accessed 16/08/2021. 7. Marmot M. The Health Gap. London: Bloomsbury Publishing, 2016. 8. Flores KF, Robledo CA, Hwang BS et al. Does maternal asthma contribute to racial/ethnic disparities in obstetrical and neonatal complications? Ann Epidemiol 2015; 25: 392– 397.e1.
{"title":"Response to Letter to the Editor ‘Adverse perinatal outcomes in the Australian Indigenous population, the role of asthma’","authors":"Vicki L. Clifton, J. Das, V. Flenady, Kym Rae","doi":"10.1111/ajo.13480","DOIUrl":"https://doi.org/10.1111/ajo.13480","url":null,"abstract":"6. Australian Institute of Health and Welfare & National Indigenous Australians Agency. Aboriginal and Torres Strait Islander Health Performance Framework; 2020. Available from URL: https://www. indig enous hpf.gov.au/. Accessed 16/08/2021. 7. Marmot M. The Health Gap. London: Bloomsbury Publishing, 2016. 8. Flores KF, Robledo CA, Hwang BS et al. Does maternal asthma contribute to racial/ethnic disparities in obstetrical and neonatal complications? Ann Epidemiol 2015; 25: 392– 397.e1.","PeriodicalId":8599,"journal":{"name":"Australian and New Zealand Journal of Obstetrics and Gynaecology","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80491434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. McCaughey, Samantha S. Mooney, Keryn Harlow, M. Healey, K. Stone
Adenomyosis is a benign disorder defined by ectopic endometrial glands within the uterine myometrium. A study by Mooney et al reported the myometrial‐cervical ratio (MCR), a novel ultrasound measurement that was found to improve the preoperative diagnosis of adenomyosis.
{"title":"The use of the myometrial‐cervical ratio in the ultrasound diagnosis of adenomyosis – A validation study","authors":"T. McCaughey, Samantha S. Mooney, Keryn Harlow, M. Healey, K. Stone","doi":"10.1111/ajo.13515","DOIUrl":"https://doi.org/10.1111/ajo.13515","url":null,"abstract":"Adenomyosis is a benign disorder defined by ectopic endometrial glands within the uterine myometrium. A study by Mooney et al reported the myometrial‐cervical ratio (MCR), a novel ultrasound measurement that was found to improve the preoperative diagnosis of adenomyosis.","PeriodicalId":8599,"journal":{"name":"Australian and New Zealand Journal of Obstetrics and Gynaecology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72862976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：