Background: Pemphigus vulgaris (PV) is a blistering autoimmune disease of the skin and mucous membranes defined histologically by intraepidermal blister due to acantholysis. Systemic corticosteroids and immunosuppressive agents had greatly improved the prognosis of pemphigus. However, steroid use often leads to metabolic complications, such as diabetes mellitus. This case report describes steroid-induced diabetes mellitus in PV, where the side effect of long-term high dosages steroid used and the method to manage it can be used as a study case.Case report: A 31-year-old man complained of new blisters from almost the entire body. He had a history of PV 1 year ago and no history of diabetes mellitus in the patient or family. He had a medication history of methylprednisolone 8 mg every 8 hours. Dermatological status showed erythema macules, extensive erosion almost on the entire body, the Nikolsky sign (+), and the Asboe-Hansen sign (+). Blood laboratory result: random blood glucose 451 mg/dl, HbA1c 12.3%. Histopathological examination: suprabasal blister, in which the basal cells still attached to the basement membrane show a “tombstone” appearance. The diagnosis was steroid-induced diabetes in pemphigus vulgaris. He was treated with steroids and insulin.Conclusion: Steroid use in PV treatment can lead to metabolic complications, such as diabetes mellitus. Regularly monitoring is needed to prevent complications due to steroid use.
{"title":"Steroid-induced diabetes mellitus in pemphigus vulgaris patient at Bali Mandara Hospital: a case report","authors":"Felicia Aviana, I. M. Birawan","doi":"10.15562/bdv.v4i2.43","DOIUrl":"https://doi.org/10.15562/bdv.v4i2.43","url":null,"abstract":"Background: Pemphigus vulgaris (PV) is a blistering autoimmune disease of the skin and mucous membranes defined histologically by intraepidermal blister due to acantholysis. Systemic corticosteroids and immunosuppressive agents had greatly improved the prognosis of pemphigus. However, steroid use often leads to metabolic complications, such as diabetes mellitus. This case report describes steroid-induced diabetes mellitus in PV, where the side effect of long-term high dosages steroid used and the method to manage it can be used as a study case.Case report: A 31-year-old man complained of new blisters from almost the entire body. He had a history of PV 1 year ago and no history of diabetes mellitus in the patient or family. He had a medication history of methylprednisolone 8 mg every 8 hours. Dermatological status showed erythema macules, extensive erosion almost on the entire body, the Nikolsky sign (+), and the Asboe-Hansen sign (+). Blood laboratory result: random blood glucose 451 mg/dl, HbA1c 12.3%. Histopathological examination: suprabasal blister, in which the basal cells still attached to the basement membrane show a “tombstone” appearance. The diagnosis was steroid-induced diabetes in pemphigus vulgaris. He was treated with steroids and insulin.Conclusion: Steroid use in PV treatment can lead to metabolic complications, such as diabetes mellitus. Regularly monitoring is needed to prevent complications due to steroid use.","PeriodicalId":8684,"journal":{"name":"Bali Dermatology and Venereology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75273836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. Syphilis in pregnancy is often asymptomatic, so early detection of syphilis is needed to prevent a poor pregnancy outcome and transmission of infection to the baby.Case: A 25-year-old woman, pregnant with her second child at 24 weeks of gestation, came without any health complaint for a routine prenatal check-up. On syphilis screening, reactive TPHA and RPR titer of 1:2 were found. The patient was diagnosed with syphilis infection in pregnancy. The patient has been treated with Benzathine Benzylpenicillin 2.4 million IU intramuscular injection once a week for 3 consecutive weeks.Conclusion: Syphilis is a sexually transmitted infection that infects pregnant women. Treponemal transmission in pregnant women was detected early in the ninth week of pregnancy. The diagnosis of syphilis was made by dark-field microscopy, treponemal antibody tests (TPHA, FTA-ABS), and non-treponemal antibody tests (VDRL, RPR). Penicillin is the gold standard therapy for syphilis in pregnant women.
{"title":"Syphilis in pregnancy at Public Health Centre III North Denpasar","authors":"Odilia Dea Novena, Gusti Ayu Vina Mery Giovani","doi":"10.15562/bdv.v4i2.54","DOIUrl":"https://doi.org/10.15562/bdv.v4i2.54","url":null,"abstract":"Introduction: Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. Syphilis in pregnancy is often asymptomatic, so early detection of syphilis is needed to prevent a poor pregnancy outcome and transmission of infection to the baby.Case: A 25-year-old woman, pregnant with her second child at 24 weeks of gestation, came without any health complaint for a routine prenatal check-up. On syphilis screening, reactive TPHA and RPR titer of 1:2 were found. The patient was diagnosed with syphilis infection in pregnancy. The patient has been treated with Benzathine Benzylpenicillin 2.4 million IU intramuscular injection once a week for 3 consecutive weeks.Conclusion: Syphilis is a sexually transmitted infection that infects pregnant women. Treponemal transmission in pregnant women was detected early in the ninth week of pregnancy. The diagnosis of syphilis was made by dark-field microscopy, treponemal antibody tests (TPHA, FTA-ABS), and non-treponemal antibody tests (VDRL, RPR). Penicillin is the gold standard therapy for syphilis in pregnant women.","PeriodicalId":8684,"journal":{"name":"Bali Dermatology and Venereology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78818818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adi Agung Anantawijaya Daryago, F. Fitriani, Soenarto Kartowigno, Inda Astri Aryani, Y. Yahya, S. Diba, A. Stephanie
Diabetes mellitus (DM) is a chronic and complex disease that affects various parts of the body. It can lead to multiple systemic complications and also cutaneous manifestation. Diabetic foot ulcer (DFU) is one of the most devastating complications of DM in dermatology. The main etiology is an increase in plasma glucose, risk factors, or comorbidities due to DM itself. Neglected DFU can lead to further complications, including high amputation and mortality rates; thus, the healing of ulcers is the main objective of the treatment. Management is divided into the standard of care and adjuvant therapies. This study aims to optimize DFU management, so it can provide proper treatment and prevent complications.
{"title":"Management of diabetic foot ulcers: dermatology perspective","authors":"Adi Agung Anantawijaya Daryago, F. Fitriani, Soenarto Kartowigno, Inda Astri Aryani, Y. Yahya, S. Diba, A. Stephanie","doi":"10.15562/bdv.v4i2.65","DOIUrl":"https://doi.org/10.15562/bdv.v4i2.65","url":null,"abstract":"Diabetes mellitus (DM) is a chronic and complex disease that affects various parts of the body. It can lead to multiple systemic complications and also cutaneous manifestation. Diabetic foot ulcer (DFU) is one of the most devastating complications of DM in dermatology. The main etiology is an increase in plasma glucose, risk factors, or comorbidities due to DM itself. Neglected DFU can lead to further complications, including high amputation and mortality rates; thus, the healing of ulcers is the main objective of the treatment. Management is divided into the standard of care and adjuvant therapies. This study aims to optimize DFU management, so it can provide proper treatment and prevent complications.","PeriodicalId":8684,"journal":{"name":"Bali Dermatology and Venereology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81437960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Putu Dyah Sawitri, I. D. Karmila, Marrietta Sugiarti Sadeli
Superficial fungal infections are one of the most common skin infection infections. It is caused by fungal pathogens and are limited to the outer layer of the skin, hair, and nails. Superficial fungal infections include dermatophytosis, superficial candidiasis, and diseases caused by Malassezia spp. Most physicians diagnose and treat superficial fungal infections based solely on clinical appearance. But unfortunately, there are many other infectious and non-infectious diseases that have similar clinical appearance.Dermoscopy is a practical and noninvasive imaging method that allows magnifying clinical surface images that are normally invisible under a magnifying lens. In diagnosing superficial mycosis, dermoscopy was found to have a higher sensitivity and specifity compared to pottasium chloride (KOH) and fungal culture.More understanding is needed about the use of dermoscopy in diagnosing superficial fungal infections in the hope of being able to provide an overview of superficial fungal infections and dermoscopy, as well as dermoscopy features in some superficial fungal infections. In this article, the author describe dermoscopic findings in various superficial fungal infections on the skin, hair, and nails.
{"title":"Dermoscopy in superficial fungal infection","authors":"Putu Dyah Sawitri, I. D. Karmila, Marrietta Sugiarti Sadeli","doi":"10.15562/bdv.v4i2.52","DOIUrl":"https://doi.org/10.15562/bdv.v4i2.52","url":null,"abstract":" Superficial fungal infections are one of the most common skin infection infections. It is caused by fungal pathogens and are limited to the outer layer of the skin, hair, and nails. Superficial fungal infections include dermatophytosis, superficial candidiasis, and diseases caused by Malassezia spp. Most physicians diagnose and treat superficial fungal infections based solely on clinical appearance. But unfortunately, there are many other infectious and non-infectious diseases that have similar clinical appearance.Dermoscopy is a practical and noninvasive imaging method that allows magnifying clinical surface images that are normally invisible under a magnifying lens. In diagnosing superficial mycosis, dermoscopy was found to have a higher sensitivity and specifity compared to pottasium chloride (KOH) and fungal culture.More understanding is needed about the use of dermoscopy in diagnosing superficial fungal infections in the hope of being able to provide an overview of superficial fungal infections and dermoscopy, as well as dermoscopy features in some superficial fungal infections. In this article, the author describe dermoscopic findings in various superficial fungal infections on the skin, hair, and nails.","PeriodicalId":8684,"journal":{"name":"Bali Dermatology and Venereology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73926711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elice Wijaya, Nitu Karna, Ida Ayu Uttari Priyadarshini
Background: Neurofibromatosis is a genetic disorder which manifests as a tumor that surrounds the nerves and several other pathologic presentations.Case: Female, 11 years old, according to history, physical examination and supporting investigation was consistent with the diagnostic criteria of type 1 neurofibromatosis (NF-1). Patient also has intellectual disability. On the patient, a tumor on the foot region that was functionally disabling was found and a surgical treatment was performed.Discussion: Cognitive disorder is the most common neurological complication in individuals with NF-1 and usually present with low intelligence quotient (IQ). There is no specific treatment to prevent the development of NF-1. However, early treatment can minimize and prevent further complication. Treatment for the patient involve multiple clinical discipline.Conclusion: A neurofibromatosis case can be diagnosed clinically alone, however, since there are many other systemic involvements that require multi-disciplinary approach.
{"title":"Case report: a child with type 1 neurofibromatosis and intellectual disability","authors":"Elice Wijaya, Nitu Karna, Ida Ayu Uttari Priyadarshini","doi":"10.15562/bdv.v4i2.55","DOIUrl":"https://doi.org/10.15562/bdv.v4i2.55","url":null,"abstract":"Background: Neurofibromatosis is a genetic disorder which manifests as a tumor that surrounds the nerves and several other pathologic presentations.Case: Female, 11 years old, according to history, physical examination and supporting investigation was consistent with the diagnostic criteria of type 1 neurofibromatosis (NF-1). Patient also has intellectual disability. On the patient, a tumor on the foot region that was functionally disabling was found and a surgical treatment was performed.Discussion: Cognitive disorder is the most common neurological complication in individuals with NF-1 and usually present with low intelligence quotient (IQ). There is no specific treatment to prevent the development of NF-1. However, early treatment can minimize and prevent further complication. Treatment for the patient involve multiple clinical discipline.Conclusion: A neurofibromatosis case can be diagnosed clinically alone, however, since there are many other systemic involvements that require multi-disciplinary approach.","PeriodicalId":8684,"journal":{"name":"Bali Dermatology and Venereology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85108856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tritya Mudita, N. M. Puspawati, I. G. A. Sattwika, A. Wirya
Introduction: Syphilis is an infection caused by Treponema pallidum of the spirochaete family.Case: A 19-year-old Balinese came with a complaint of red spots on the palms of the hands and feet one month ago. The patient has a hearing disability and is currently enrolled in a special-needs school in Denpasar. VDRL examination with reactive results with titer 1:256 and TPHA reactive with TPHA titer 1:5120. The patient received benzathine penicillin G 2.4 million units intramuscularly. Significant improvement was obtained, and the serological test was decreased.Discussion: Syphilis transmits through sexual contact, vertically from pregnant women to their fetuses, through needle sharing. People with hearing disabilities and adolescents are considered vulnerable as objects of harassment and sexual violence.Conclusion: People with disabilities and adolescents are vulnerable to sexually transmitted diseases. Information on reproductive health and sexually transmitted diseases need to be more readily available for people with disabilities. Secondary syphilis therapy with a single dose of benzathine penicillin is effective from clinical or serological observations.
{"title":"Secondary syphilis with stage III HIV in an adolescent deaf male with a history of sexual relationship with men: a case report","authors":"Tritya Mudita, N. M. Puspawati, I. G. A. Sattwika, A. Wirya","doi":"10.15562/bdv.v4i1.51","DOIUrl":"https://doi.org/10.15562/bdv.v4i1.51","url":null,"abstract":"Introduction: Syphilis is an infection caused by Treponema pallidum of the spirochaete family.Case: A 19-year-old Balinese came with a complaint of red spots on the palms of the hands and feet one month ago. The patient has a hearing disability and is currently enrolled in a special-needs school in Denpasar. VDRL examination with reactive results with titer 1:256 and TPHA reactive with TPHA titer 1:5120. The patient received benzathine penicillin G 2.4 million units intramuscularly. Significant improvement was obtained, and the serological test was decreased.Discussion: Syphilis transmits through sexual contact, vertically from pregnant women to their fetuses, through needle sharing. People with hearing disabilities and adolescents are considered vulnerable as objects of harassment and sexual violence.Conclusion: People with disabilities and adolescents are vulnerable to sexually transmitted diseases. Information on reproductive health and sexually transmitted diseases need to be more readily available for people with disabilities. Secondary syphilis therapy with a single dose of benzathine penicillin is effective from clinical or serological observations.","PeriodicalId":8684,"journal":{"name":"Bali Dermatology and Venereology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73464997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Syphilis frequently presents in tandem with conditions such as HIV, and the prevalence is increasing, particularly in men who have sex with men (MSM). The most common and recognizable manifestations are usually the secondary stage, characterized with or without constitutional symptoms. Choosing the first line or alternative therapy was based on patient condition and the availability of the medicine.Case report: It was reported a 22-year-old man with secondary syphilis and HIV infection. The diagnosis was established based on erythema and hyperpigmented maculopapular lesions with the scale on the forearms, palms, back, feet, and soles without pruritic sensation, a history of the same-sex sexual partners and the titer of VDRL 1:64, TPHA 1:2560. The patient also has a low CD4 level, and HIV-1 RNA was detected on a blood test. Patients received azithromycin 2 grams orally and continued by doxycycline twice a day for 30 days and also treated for the HIV Infection.Conclusion: Skin disorders have improved rapidly and significantly, accompanied by decreased VDRL titer.
{"title":"Secondary syphilis with HIV infection in men who have sex with men (MSM) patient treated with azithromycin and doxycycline: a case report","authors":"Hani Lusyana, Agus Walujo, Lina Damayanti","doi":"10.15562/bdv.v4i1.46","DOIUrl":"https://doi.org/10.15562/bdv.v4i1.46","url":null,"abstract":"Introduction: Syphilis frequently presents in tandem with conditions such as HIV, and the prevalence is increasing, particularly in men who have sex with men (MSM). The most common and recognizable manifestations are usually the secondary stage, characterized with or without constitutional symptoms. Choosing the first line or alternative therapy was based on patient condition and the availability of the medicine.Case report: It was reported a 22-year-old man with secondary syphilis and HIV infection. The diagnosis was established based on erythema and hyperpigmented maculopapular lesions with the scale on the forearms, palms, back, feet, and soles without pruritic sensation, a history of the same-sex sexual partners and the titer of VDRL 1:64, TPHA 1:2560. The patient also has a low CD4 level, and HIV-1 RNA was detected on a blood test. Patients received azithromycin 2 grams orally and continued by doxycycline twice a day for 30 days and also treated for the HIV Infection.Conclusion: Skin disorders have improved rapidly and significantly, accompanied by decreased VDRL titer.","PeriodicalId":8684,"journal":{"name":"Bali Dermatology and Venereology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73229009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sissy Sissy, A. Santoso, Dewi Gotama, L. M. Rusyati
Background: Varicella-zoster virus (VZV) is a virus of human neurotropic that remains within ganglionic neurons in a latent state after the primary infection throughout the entire neuroaxis.Case: A male patient, 32 years old Javanese, consulted from the pulmonary division with complaints of vesicular eruption in the facial area on September 27, 2020. The patient was diagnosed with ophthalmic herpes zoster and a mild COVID-19 infection since 2 days ago and was hospitalized. Management in patients was acyclovir, methylprednisolone, with analgesics and vitamins. COVID-19 as co-infection and other viruses has been known, but infrequently affect the respiratory tract.Conclusion: Herpes zoster patient should ruled out the COVID-19 and maximize the precaution for personal safety equipment until the SARS-CoV-2 is excluded.
{"title":"COVID-19 and ophthalmic herpes zoster co-infection in immunocompetent patient","authors":"Sissy Sissy, A. Santoso, Dewi Gotama, L. M. Rusyati","doi":"10.15562/bdv.v4i1.45","DOIUrl":"https://doi.org/10.15562/bdv.v4i1.45","url":null,"abstract":"Background: Varicella-zoster virus (VZV) is a virus of human neurotropic that remains within ganglionic neurons in a latent state after the primary infection throughout the entire neuroaxis.Case: A male patient, 32 years old Javanese, consulted from the pulmonary division with complaints of vesicular eruption in the facial area on September 27, 2020. The patient was diagnosed with ophthalmic herpes zoster and a mild COVID-19 infection since 2 days ago and was hospitalized. Management in patients was acyclovir, methylprednisolone, with analgesics and vitamins. COVID-19 as co-infection and other viruses has been known, but infrequently affect the respiratory tract.Conclusion: Herpes zoster patient should ruled out the COVID-19 and maximize the precaution for personal safety equipment until the SARS-CoV-2 is excluded.","PeriodicalId":8684,"journal":{"name":"Bali Dermatology and Venereology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75007704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Laboratory investigation for genital herpes (GH) includes serologic tests and polymerase chain reaction (PCR) with different sensitivity and specificity; occasionally, the results are not conclusive. Clinical symptoms are often atypical. We report a case of GH in HIV-infected patients with a non-reactive serologic test but positive PCR.Case Description: A 29-years old HIV-positive man presented with multiple painful shallow ulcers with pus on his penis in the last five days. PCR examination showed a positive result, whereas anti-HSV 1 IgM, anti-HSV 2 IgM, anti-HSV 2 IgG, VDRL, and TPHA were negative. The anti-HSV- 1 IgG result was reactive with a CD4 value of 122 cells/μL. The patient was given Acyclovir 3x400 mg for ten days and Co-amoxiclav 3x625 mg for seven days. Significant improvement was obtained, and the pain subsided.Conclusion: Clinical features of GH in infected HIV patients are often atypical and resemble other genital ulcers, thus requiring additional investigations. The serologic test may sometimes present a false negative, whereas PCR is much more sensitive and specific, nearing 100%. In patients with HIV infection, GH diagnosis at an early stage can shorten the course of the disease and prevent complications.
{"title":"Discrepancy of PCR and serologic test on genital herpes: a case report","authors":"Jhauharina Rizki Fadhilla","doi":"10.15562/bdv.v4i1.49","DOIUrl":"https://doi.org/10.15562/bdv.v4i1.49","url":null,"abstract":"Background: Laboratory investigation for genital herpes (GH) includes serologic tests and polymerase chain reaction (PCR) with different sensitivity and specificity; occasionally, the results are not conclusive. Clinical symptoms are often atypical. We report a case of GH in HIV-infected patients with a non-reactive serologic test but positive PCR.Case Description: A 29-years old HIV-positive man presented with multiple painful shallow ulcers with pus on his penis in the last five days. PCR examination showed a positive result, whereas anti-HSV 1 IgM, anti-HSV 2 IgM, anti-HSV 2 IgG, VDRL, and TPHA were negative. The anti-HSV- 1 IgG result was reactive with a CD4 value of 122 cells/μL. The patient was given Acyclovir 3x400 mg for ten days and Co-amoxiclav 3x625 mg for seven days. Significant improvement was obtained, and the pain subsided.Conclusion: Clinical features of GH in infected HIV patients are often atypical and resemble other genital ulcers, thus requiring additional investigations. The serologic test may sometimes present a false negative, whereas PCR is much more sensitive and specific, nearing 100%. In patients with HIV infection, GH diagnosis at an early stage can shorten the course of the disease and prevent complications.","PeriodicalId":8684,"journal":{"name":"Bali Dermatology and Venereology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89503881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Psoriasis is a chronic inflammatory disease of the skin affecting patients of all ages, both males and females. Currently, the psoriasis area and severity index (PASI) method is the gold standard in assessing the severity of psoriasis. Phototherapy narrowband ultraviolet B (NBUVB) is one of the modalities of psoriasis therapy which is relatively safe and effective for repairing psoriasis lesions. Patient satisfaction with phototherapy, which can be assessed using a questionnaire, serves to determine the patient's motivation in carrying out routine therapy.Objective: This study was designed to determine the correlation between the level of NBUVB phototherapy satisfaction with PASI improvement.Method: The study subjects were 22 plaque-type psoriasis vulgaris patients who underwent NBUVB phototherapy from May 2018 to October 2018 in the dermatovenereology outpatient clinic of Dr. Moewardi Hospital Surakarta. Subjects filled in the Treatment Satisfaction Questionnaire for Medication (TSQM) included questions about satisfaction with NBUVB phototherapy, and PASI scores were measured before and after NBUVB phototherapy.Results: The data were analyzed with the Pearson correlation test with a significance value of p <0.05. There are significant differences between PASI before and after giving 24 times phototherapy with a value of p<0.05.Conclusion: There was a significant correlation between the degree of PASI improvement and the global patient satisfaction with NBUVB phototherapy.
{"title":"The correlation between patient satisfaction treatment of narrowband ultraviolet B phototherapy and the improvement of psoriasis severity index","authors":"Putti Fatiharani Dewi","doi":"10.15562/bdv.v4i1.48","DOIUrl":"https://doi.org/10.15562/bdv.v4i1.48","url":null,"abstract":"Background: Psoriasis is a chronic inflammatory disease of the skin affecting patients of all ages, both males and females. Currently, the psoriasis area and severity index (PASI) method is the gold standard in assessing the severity of psoriasis. Phototherapy narrowband ultraviolet B (NBUVB) is one of the modalities of psoriasis therapy which is relatively safe and effective for repairing psoriasis lesions. Patient satisfaction with phototherapy, which can be assessed using a questionnaire, serves to determine the patient's motivation in carrying out routine therapy.Objective: This study was designed to determine the correlation between the level of NBUVB phototherapy satisfaction with PASI improvement.Method: The study subjects were 22 plaque-type psoriasis vulgaris patients who underwent NBUVB phototherapy from May 2018 to October 2018 in the dermatovenereology outpatient clinic of Dr. Moewardi Hospital Surakarta. Subjects filled in the Treatment Satisfaction Questionnaire for Medication (TSQM) included questions about satisfaction with NBUVB phototherapy, and PASI scores were measured before and after NBUVB phototherapy.Results: The data were analyzed with the Pearson correlation test with a significance value of p <0.05. There are significant differences between PASI before and after giving 24 times phototherapy with a value of p<0.05.Conclusion: There was a significant correlation between the degree of PASI improvement and the global patient satisfaction with NBUVB phototherapy.","PeriodicalId":8684,"journal":{"name":"Bali Dermatology and Venereology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77061201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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