Pub Date : 2023-11-10DOI: 10.29011/2575-8241.001327
{"title":"Defining The Disease of Movement Dysfunction Related Low Back Pain - An Observational Study and Description of The Necessary Paradigm Shift Required to Cure the Root Cause of Globally Prevalent Low Back Pain Symptoms","authors":"","doi":"10.29011/2575-8241.001327","DOIUrl":"https://doi.org/10.29011/2575-8241.001327","url":null,"abstract":"","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139280714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.29011/2575-8241.001322
Objective: To explore the current situation of end-of-life care self-efficacy of junior nurses in the operating room of a tertiary general hospital and the factors affecting it, and to provide a basis for improving the quality of end-of-life care services for junior nurses in the operating room. Methods: A cross-sectional survey of 185 clinical nurses in a tertiary general hospital in Guangdong Province was conducted using a convenience sampling method, a general information questionnaire
{"title":"Comparatively Low End-of-Life Care Self-Efficacy Among Junior Nurses in the Operating Room in China: A Cross-Sectional Survey","authors":"","doi":"10.29011/2575-8241.001322","DOIUrl":"https://doi.org/10.29011/2575-8241.001322","url":null,"abstract":"Objective: To explore the current situation of end-of-life care self-efficacy of junior nurses in the operating room of a tertiary general hospital and the factors affecting it, and to provide a basis for improving the quality of end-of-life care services for junior nurses in the operating room. Methods: A cross-sectional survey of 185 clinical nurses in a tertiary general hospital in Guangdong Province was conducted using a convenience sampling method, a general information questionnaire","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135646450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.29011/2575-8241.001324
Abstract Purpose: The consequences of Anterior Cruciate Ligament (ACL) injury and subsequent reconstruction in handball players are understudied. The aim of the present study is to present the effects of ACL reconstruction exclusively on handball players regarding return to play. Methods: Fourteen knees with an ACL tear in twelve patients were included in the study. Nine injuries ( ) occurred during games, and five ( during training. The mechanism of injury was non-contact in of cases. All cases were treated with a hamstrings autograft. Results: The athletes returned to unrestricted full team training in a mean of 7.7 months. Return to competitive play was achieved in twelve of the fourteen cases ( in a mean time of 9.6 months post-operatively. Nine of the athletes that returned to play ( ) reached the same level of competition as before injury. At a mean follow-up of 37.1 months post-operatively, of the players included in the study and of those that returned to play were still active players; all playing at their pre-injury competition level. There was one recurrence of an ACL tear ( , while two athletes ( had a contralateral ACL rupture during the follow-up period. All athletes - including the ones that quitted - had excellent knee scores at the latest follow-up. IKDC mean score was 94.7 Lysholm mean score was 95 EuroQoL mean score was 100, and KOOS mean score was 97.3. Conclusions: A high proportion of elite handball players can return to play following ACL reconstruction with a low rate of recurrence. However, not all players can stay in the sport for long and this should be kept in mind when an ACL tear occurs.
{"title":"Return to Play and Long-Term Participation Following ACL Reconstruction in Elite Handball Players","authors":"","doi":"10.29011/2575-8241.001324","DOIUrl":"https://doi.org/10.29011/2575-8241.001324","url":null,"abstract":"Abstract Purpose: The consequences of Anterior Cruciate Ligament (ACL) injury and subsequent reconstruction in handball players are understudied. The aim of the present study is to present the effects of ACL reconstruction exclusively on handball players regarding return to play. Methods: Fourteen knees with an ACL tear in twelve patients were included in the study. Nine injuries ( ) occurred during games, and five ( during training. The mechanism of injury was non-contact in of cases. All cases were treated with a hamstrings autograft. Results: The athletes returned to unrestricted full team training in a mean of 7.7 months. Return to competitive play was achieved in twelve of the fourteen cases ( in a mean time of 9.6 months post-operatively. Nine of the athletes that returned to play ( ) reached the same level of competition as before injury. At a mean follow-up of 37.1 months post-operatively, of the players included in the study and of those that returned to play were still active players; all playing at their pre-injury competition level. There was one recurrence of an ACL tear ( , while two athletes ( had a contralateral ACL rupture during the follow-up period. All athletes - including the ones that quitted - had excellent knee scores at the latest follow-up. IKDC mean score was 94.7 Lysholm mean score was 95 EuroQoL mean score was 100, and KOOS mean score was 97.3. Conclusions: A high proportion of elite handball players can return to play following ACL reconstruction with a low rate of recurrence. However, not all players can stay in the sport for long and this should be kept in mind when an ACL tear occurs.","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135646448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.29011/2575-8241.001323
Objective: To investigate the social support, work stress and retention intention of nurses in newly built hospital districts and to explore their correlation. Methods: Convenience sampling, general information questionnaire, social support rating scale, nurses’ work stressor scale, and nurses’ willingness to stay in the job questionnaire were used to investigate 134 nurses in newly built hospital districts. Results: The total score of willingness to stay (19.12±4.29), social support was significantly positively correlated with willingness to stay (R=0.354, P<0.01), and work stress was significantly negatively correlated with willingness to stay (R=-0.63, P<0.01). Conclusions: Nursing managers should take appropriate measures to improve social support for nurses, reduce nurses’ work pressure, and then enhance nurses’ willingness to stay in their jobs and stabilize the nursing team.
{"title":"Nurses with Low Willingness to Stay in New Hospital District and Need More Social Support: A Cross-Sectional Survey","authors":"","doi":"10.29011/2575-8241.001323","DOIUrl":"https://doi.org/10.29011/2575-8241.001323","url":null,"abstract":"Objective: To investigate the social support, work stress and retention intention of nurses in newly built hospital districts and to explore their correlation. Methods: Convenience sampling, general information questionnaire, social support rating scale, nurses’ work stressor scale, and nurses’ willingness to stay in the job questionnaire were used to investigate 134 nurses in newly built hospital districts. Results: The total score of willingness to stay (19.12±4.29), social support was significantly positively correlated with willingness to stay (R=0.354, P<0.01), and work stress was significantly negatively correlated with willingness to stay (R=-0.63, P<0.01). Conclusions: Nursing managers should take appropriate measures to improve social support for nurses, reduce nurses’ work pressure, and then enhance nurses’ willingness to stay in their jobs and stabilize the nursing team.","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135646449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.29011/2575-8241.001321
Introduction: Conventional radiographs are not doing justice to the complexity of 3D hip pathologies. Some methods based on 3D technology did not find their way to clinical practice. The goal of this study was to develop a 3D measurement method (named spidermap) for the acetabular coverage that can be used for the diagnosis of DDH as well as for the quantification of correction after Periacetabular Osteotomy (PAO). Methods: In a first step we defined the threshold between physiological and dysplastic hips using this spidermap and in a second step we compared physiological to surgically treated dysplastic hips to quantify the correction. The population included three groups: Group A consisted of 18 physiological, group B of 21 dysplastic and group C of 8 surgically corrected hips. CT scans were used to calculate femoral head
{"title":"A CT based 3D Algorithm for Diagnosis of DDH and Quantification of Surgical Correction","authors":"","doi":"10.29011/2575-8241.001321","DOIUrl":"https://doi.org/10.29011/2575-8241.001321","url":null,"abstract":"Introduction: Conventional radiographs are not doing justice to the complexity of 3D hip pathologies. Some methods based on 3D technology did not find their way to clinical practice. The goal of this study was to develop a 3D measurement method (named spidermap) for the acetabular coverage that can be used for the diagnosis of DDH as well as for the quantification of correction after Periacetabular Osteotomy (PAO). Methods: In a first step we defined the threshold between physiological and dysplastic hips using this spidermap and in a second step we compared physiological to surgically treated dysplastic hips to quantify the correction. The population included three groups: Group A consisted of 18 physiological, group B of 21 dysplastic and group C of 8 surgically corrected hips. CT scans were used to calculate femoral head","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136238298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-06DOI: 10.29011/2575-8241.001318
Bryce Allen Hendrix, Aaron Schrayer, John C.P. Floyd
Metal has long been the basis for implants used in orthopedic surgery. The first metals used were stainless steel and cobalt-chrome based alloys with progression through the years to include titanium, nickel, and most recently, carbon fiber.[1] Multiple previous studies describe carbon fiber as a safe, biocompatible material that can be used in problematic fractures. [2-6] However to our knowledge, no study has examined the use of carbon fiber specifically in buttress plate application. Compared to conventional metal implants, carbon fiber offers several potential benefits. It provides a modulus of elasticity closer to that of bone, improved fatigue strength, and more complete imaging compatibility. [3-6] In addition, carbon fiber has a large elastic deformation phase with little to no plastic deformation, and it is this distinctive quality that would seem to make carbon fiber potentially ideal for buttress plate fracture fixation. The objective of this case series was to outline the preliminary experience of carbon fiber buttress plating in ankle fractures. This study was performed at a level II trauma center and includes four patients that underwent open reduction and internal fixation with carbon fiber buttress plating for either a bimalleolar equivalent fracture, bimalleolar ankle fracture, or trimalleolar ankle fracture. The main outcome measure included radiographic fracture visualization of healing, adverse tissue reaction, infection, subsequent fracture, or hardware failure. Overall, all patients achieved union with no adverse effects, drawing to the conclusion that carbon fiber is a safe and effective alternative when used in a buttress plate fashion,
{"title":"Preliminary Experience of Carbon Fiber Buttress Plating: A Case Series","authors":"Bryce Allen Hendrix, Aaron Schrayer, John C.P. Floyd","doi":"10.29011/2575-8241.001318","DOIUrl":"https://doi.org/10.29011/2575-8241.001318","url":null,"abstract":"Metal has long been the basis for implants used in orthopedic surgery. The first metals used were stainless steel and cobalt-chrome based alloys with progression through the years to include titanium, nickel, and most recently, carbon fiber.[1] Multiple previous studies describe carbon fiber as a safe, biocompatible material that can be used in problematic fractures. [2-6] However to our knowledge, no study has examined the use of carbon fiber specifically in buttress plate application. Compared to conventional metal implants, carbon fiber offers several potential benefits. It provides a modulus of elasticity closer to that of bone, improved fatigue strength, and more complete imaging compatibility. [3-6] In addition, carbon fiber has a large elastic deformation phase with little to no plastic deformation, and it is this distinctive quality that would seem to make carbon fiber potentially ideal for buttress plate fracture fixation. The objective of this case series was to outline the preliminary experience of carbon fiber buttress plating in ankle fractures. This study was performed at a level II trauma center and includes four patients that underwent open reduction and internal fixation with carbon fiber buttress plating for either a bimalleolar equivalent fracture, bimalleolar ankle fracture, or trimalleolar ankle fracture. The main outcome measure included radiographic fracture visualization of healing, adverse tissue reaction, infection, subsequent fracture, or hardware failure. Overall, all patients achieved union with no adverse effects, drawing to the conclusion that carbon fiber is a safe and effective alternative when used in a buttress plate fashion,","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41333198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-16DOI: 10.29011/2575-8241.001316
Shahid A Akhund, Khalid Said, Khalid S. Mohammad
Complications associated with advanced cancer pose a clinical challenge, particularly when bone metastases are involved, as they can worsen the prognosis and reduce the patient’s chances of survival. Solid tumors, such as those originating from the breast, prostate, and lungs, can potentially metastasize to bone. Mineralized bone matrices contain potent growth factors and cytokines. The bone microenvironment is distinctive, furnishing prolific soil for cancer cell proliferation. Following tumor-induced bone destruction by osteoclast, the Transforming Growth Factor (TGFβ) is released from the mineralized bone matrix. It is one of the most abundant growth factors released from the bone matrix. TGFβ stimulates tumor cell secretion of factors that accelerate bone resorption and stimulate tumor cell colonization. Consequently, TGFβ is essential for fueling cancer’s vicious cycle of cancer growth and bone destruction. In addition, TGFβ promotes Epithelial-Mesenchymal Transition (EMT), increasing cell invasiveness, angiogenesis, and metastasis progression. Emerging evidence demonstrates that TGFβ inhibits immune responses, allowing opportunistic cancer cells to evade immune checkpoints and promote bone metastasis. By inhibiting TGFβ signaling pathways, cancer progression in the bone could be broken, EMT could be reversed, and immune response could be improved. However, the dual function of TGFβ as both a tumor suppressor and an enhancer pose a formidable obstacle to developing therapeutics that target TGFβ signaling. This review delves into the significance of TGFβ in the advancement of cancer and bone metastases, in addition to examining the current therapeutic prospects of TGFβ pathway targeting.
{"title":"Mechanism of TGFβ in Bone Metastases and its Potential Therapeutic Uses","authors":"Shahid A Akhund, Khalid Said, Khalid S. Mohammad","doi":"10.29011/2575-8241.001316","DOIUrl":"https://doi.org/10.29011/2575-8241.001316","url":null,"abstract":"Complications associated with advanced cancer pose a clinical challenge, particularly when bone metastases are involved, as they can worsen the prognosis and reduce the patient’s chances of survival. Solid tumors, such as those originating from the breast, prostate, and lungs, can potentially metastasize to bone. Mineralized bone matrices contain potent growth factors and cytokines. The bone microenvironment is distinctive, furnishing prolific soil for cancer cell proliferation. Following tumor-induced bone destruction by osteoclast, the Transforming Growth Factor (TGFβ) is released from the mineralized bone matrix. It is one of the most abundant growth factors released from the bone matrix. TGFβ stimulates tumor cell secretion of factors that accelerate bone resorption and stimulate tumor cell colonization. Consequently, TGFβ is essential for fueling cancer’s vicious cycle of cancer growth and bone destruction. In addition, TGFβ promotes Epithelial-Mesenchymal Transition (EMT), increasing cell invasiveness, angiogenesis, and metastasis progression. Emerging evidence demonstrates that TGFβ inhibits immune responses, allowing opportunistic cancer cells to evade immune checkpoints and promote bone metastasis. By inhibiting TGFβ signaling pathways, cancer progression in the bone could be broken, EMT could be reversed, and immune response could be improved. However, the dual function of TGFβ as both a tumor suppressor and an enhancer pose a formidable obstacle to developing therapeutics that target TGFβ signaling. This review delves into the significance of TGFβ in the advancement of cancer and bone metastases, in addition to examining the current therapeutic prospects of TGFβ pathway targeting.","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48375417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-07DOI: 10.29011/2575-8241.001314
Christina Karampampa, Efthymios Papasoulis, Dimitrios Hatzimanouil, Georgios Koutras, Trifon Totlis, I. Terzidis
) The Effects of Exercise with Blood Flow Restriction (BFR) in the Post Operative Rehabilitation of Anterior Cruciate Ligament (ACL) Reconstruction Patients: A Case Series
)血流量限制运动（BFR）在前交叉韧带（ACL）重建患者术后康复中的作用：一系列病例
{"title":"The Effects of Exercise with Blood Flow Restriction (BFR) in the Post Operative Rehabilitation of Anterior Cruciate Ligament (ACL) Reconstruction Patients: A Case Series","authors":"Christina Karampampa, Efthymios Papasoulis, Dimitrios Hatzimanouil, Georgios Koutras, Trifon Totlis, I. Terzidis","doi":"10.29011/2575-8241.001314","DOIUrl":"https://doi.org/10.29011/2575-8241.001314","url":null,"abstract":") The Effects of Exercise with Blood Flow Restriction (BFR) in the Post Operative Rehabilitation of Anterior Cruciate Ligament (ACL) Reconstruction Patients: A Case Series","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41439476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-28DOI: 10.29011/2575-8241.001313
Lauren Steiner, Anne Bodensteiner, Nathaniel R. Johnson
Although hypermobile Ehlers-Danlos Syndrome and hypermobility spectrum disorders are best known for musculoskeletal manifestations such as tendon ruptures, tendonitis, osteoarthritis
{"title":"Gastrointestinal Manifestations of Hypermobile Ehlers-Danlos Syndrome and Dietary Approaches Related to Their Management","authors":"Lauren Steiner, Anne Bodensteiner, Nathaniel R. Johnson","doi":"10.29011/2575-8241.001313","DOIUrl":"https://doi.org/10.29011/2575-8241.001313","url":null,"abstract":"Although hypermobile Ehlers-Danlos Syndrome and hypermobility spectrum disorders are best known for musculoskeletal manifestations such as tendon ruptures, tendonitis, osteoarthritis","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49366784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-12DOI: 10.29011/2575-8241.001311
Objectives: To investigate the value of PLR and LMR at admission for predicting in-hospital mortality in elderly patients with hip fracture (HF). Design: Prospective study. Setting
{"title":"Platelet-to-Lymphocyte Ratio (PLR) and Lymphocyte-to-Monocyte Ratio (LMR) at Admission Predict Survival in Hip Fracture Patients","authors":"","doi":"10.29011/2575-8241.001311","DOIUrl":"https://doi.org/10.29011/2575-8241.001311","url":null,"abstract":"Objectives: To investigate the value of PLR and LMR at admission for predicting in-hospital mortality in elderly patients with hip fracture (HF). Design: Prospective study. Setting","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43284125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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