1. Samples of cutaneous sebum were taken from different skin regions, according to the method of Herrmann and Prose. 2. Some samples were removed from the skin using diethyl ether, while others were removed under similar conditions, with cyclohexane. 3. As a rule, thin-layer chromatography revealed darker, clearer and more numerous bands after the use of diethyl ether, than after the use of cyclohexane. However, some exceptions were seen. 4. The chromatograms showed individual differences while the differences between the samples taken from different skin regions of one and the same person were less considerable. 5. Despite the individual differences, the samples taken from persons without skin diseases showed some characteristic features.
{"title":"[Effects of various solvents on skin surface lipid composition].","authors":"H G Glasemann, F Herrmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>1. Samples of cutaneous sebum were taken from different skin regions, according to the method of Herrmann and Prose. 2. Some samples were removed from the skin using diethyl ether, while others were removed under similar conditions, with cyclohexane. 3. As a rule, thin-layer chromatography revealed darker, clearer and more numerous bands after the use of diethyl ether, than after the use of cyclohexane. However, some exceptions were seen. 4. The chromatograms showed individual differences while the differences between the samples taken from different skin regions of one and the same person were less considerable. 5. Despite the individual differences, the samples taken from persons without skin diseases showed some characteristic features.</p>","PeriodicalId":8796,"journal":{"name":"Berufs-Dermatosen","volume":"23 1","pages":"1-15"},"PeriodicalIF":0.0,"publicationDate":"1975-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12303937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the present study the contact irritative--eczematogenic--effect of alkaline protease enzymes (PE) contained in syndet laundry detergents has been investigated. The method employed was the occlusive epicutaneous test (ET) involving the use of increasing serial dilutions of PE and various times of exposure. The tests were made on sympton-free skin, on skin showing premorbid or slight irritative changes, on skin previously acid- or base-treated, in the presence of increased skin permeability and following the skin stripping method. The results obtained in the 912 test series indicate that the PEs tested ("Tenzym prilled" Grindstedvoerkek, and "Maxatase" Gist-Brocases) caused no irritation or other damage to the intact or slightly lesioned skin even in response to close contact lasting several days. When as a result of increased irritation, or for other reasons, the PEs may be assumed to penetrate into the subcorneal layers, they may exert a proteolytic effect, as manifested in the increasing number of positive ETs. In such cases the PE concentrations exceeded by far those employed in the commercial detergents. It is most likely that the skin changes noted in connection with the use of bioactive laundry detergents are due not to the PE content of these detergents, but to other factors.
{"title":"Skin irritancy and sensitivity to laundry detergents containing proteolytic enzymes. Part I.","authors":"M Valér","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the present study the contact irritative--eczematogenic--effect of alkaline protease enzymes (PE) contained in syndet laundry detergents has been investigated. The method employed was the occlusive epicutaneous test (ET) involving the use of increasing serial dilutions of PE and various times of exposure. The tests were made on sympton-free skin, on skin showing premorbid or slight irritative changes, on skin previously acid- or base-treated, in the presence of increased skin permeability and following the skin stripping method. The results obtained in the 912 test series indicate that the PEs tested (\"Tenzym prilled\" Grindstedvoerkek, and \"Maxatase\" Gist-Brocases) caused no irritation or other damage to the intact or slightly lesioned skin even in response to close contact lasting several days. When as a result of increased irritation, or for other reasons, the PEs may be assumed to penetrate into the subcorneal layers, they may exert a proteolytic effect, as manifested in the increasing number of positive ETs. In such cases the PE concentrations exceeded by far those employed in the commercial detergents. It is most likely that the skin changes noted in connection with the use of bioactive laundry detergents are due not to the PE content of these detergents, but to other factors.</p>","PeriodicalId":8796,"journal":{"name":"Berufs-Dermatosen","volume":"23 1","pages":"16-30"},"PeriodicalIF":0.0,"publicationDate":"1975-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12303938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The author reports the results of patch tests using various aromatic compounds in subjects sensitized to PPD. It was found that aromatic nitro and hydroxyl compounds as well as secondary and tertiary amines do not cause cross-reactions. Positive reactions were obtained only with primary aromatic amines, independently of the position of the amino group in the ring-para, ortho or meta.
{"title":"Studies on hypersensitivity to \"para group\".","authors":"D Kleniewska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author reports the results of patch tests using various aromatic compounds in subjects sensitized to PPD. It was found that aromatic nitro and hydroxyl compounds as well as secondary and tertiary amines do not cause cross-reactions. Positive reactions were obtained only with primary aromatic amines, independently of the position of the amino group in the ring-para, ortho or meta.</p>","PeriodicalId":8796,"journal":{"name":"Berufs-Dermatosen","volume":"23 1","pages":"31-6"},"PeriodicalIF":0.0,"publicationDate":"1975-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12303939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Procedure for the recognition of occupational diseases, from the medical report to the final decision].","authors":"M Kühl","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8796,"journal":{"name":"Berufs-Dermatosen","volume":"22 4","pages":"143-55"},"PeriodicalIF":0.0,"publicationDate":"1974-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15388157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Alkali resistance of the skin in adolescents and its evaluation].","authors":"H Schubert, A Ziegler, V Ziegler, R Apel","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8796,"journal":{"name":"Berufs-Dermatosen","volume":"22 4","pages":"160-8"},"PeriodicalIF":0.0,"publicationDate":"1974-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15388158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Skin tolerance of flame proof fabric made of poly(terephthaloyl)-oxalic acid bis-amidrazone (PTO)].","authors":"W Nesswetha","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8796,"journal":{"name":"Berufs-Dermatosen","volume":"22 1","pages":"28-33"},"PeriodicalIF":0.0,"publicationDate":"1974-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15927312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Use of radioisotopes in dermatologic diagnosis].","authors":"V Kubícková, M Kubícek","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8796,"journal":{"name":"Berufs-Dermatosen","volume":"22 1","pages":"23-8"},"PeriodicalIF":0.0,"publicationDate":"1974-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15927311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}