首页 > 最新文献

Quality in primary care最新文献

英文 中文
Knowledge, attitude and practice of danger signs during pregnancy among mothers attending antenatal care at Melka Oda hospital, southeast Ethiopia 在埃塞俄比亚东南部Melka Oda医院接受产前护理的母亲对怀孕期间危险迹象的知识、态度和做法
Pub Date : 2021-01-01 DOI: 10.36648/1479-1072.29.3.41-46
Bruck Tesfaye, Geroma Morka
Background: Danger signs of pregnancies are a signs that women encounter during pregnancy, child birth and postpartum which is fatal for both Mather and child health. It is important, to know these warning signs for women and health care providers to rule out serious complications and initiate treatment immediately. Objectives: To determine the level of knowledge, attitude, and practice of pregnant mothers on danger signs during pregnancy among antenatal care attendants at Malka Oda general Hospital, 2019. Methods: A cross-sectional study was conducted among 208 pregnant women attending Antenatal Care from March 11-June 20/2019. A total 208 pregnant mother was selected randomly using Systematic random sampling technique. Data was collected by face to face interview. Data were processed and Analyzed. Results: This study found that 80(38.5%) were heard about obstetric danger signs while 128(61.5%) were not. One hundred ninety-two (92.3%), 15(7.2%) mothers agreed on importance of seeking medical advice on dangerous signs during pregnancy. Sixty-two (29.8%) had experienced any of danger sign during pregnancy. Of those who had experienced any of the danger signs, 59(95.2%) were sought medical care while 3 of the mothers reported that they sought care from traditional birth attendants. Conclusion: The study showed that More than two fourth of the study participants had good knowledge about danger signs during pregnancy and large number of participants had good practice. In addition, almost two over four of the studied pregnant mothers had a positive attitude towards danger sign during pregnancy.
背景:怀孕危险迹象是妇女在怀孕、分娩和产后遇到的一种迹象,对母亲和儿童健康都是致命的。了解这些警告信号对妇女和卫生保健提供者排除严重并发症并立即开始治疗是很重要的。目的:了解2019年Malka Oda综合医院产前护理人员对妊娠危险体征的知识、态度和实践水平。方法:对2019年3月11日至6月20日期间参加产前护理的208名孕妇进行横断面研究。采用系统随机抽样方法,随机抽取208名孕妇。数据采用面对面访谈的方式收集。对数据进行处理和分析。结果:80例(38.5%)被告知分娩危险体征,128例(61.5%)未被告知。192名(92.3%)、15名(7.2%)母亲同意就怀孕期间的危险迹象寻求医疗咨询的重要性。62例(29.8%)在怀孕期间出现过任何危险迹象。在经历过任何危险迹象的妇女中,59人(95.2%)寻求医疗护理,而3名母亲报告说她们向传统助产士寻求护理。结论:研究表明,超过四分之二的研究参与者对怀孕期间的危险迹象有很好的了解,大量参与者有良好的实践。此外,近四分之二的孕妇对怀孕期间的危险信号持积极态度。
{"title":"Knowledge, attitude and practice of danger signs during pregnancy among mothers attending antenatal care at Melka Oda hospital, southeast Ethiopia","authors":"Bruck Tesfaye, Geroma Morka","doi":"10.36648/1479-1072.29.3.41-46","DOIUrl":"https://doi.org/10.36648/1479-1072.29.3.41-46","url":null,"abstract":"Background: Danger signs of pregnancies are a signs that women encounter during pregnancy, child birth and postpartum which is fatal for both Mather and child health. It is important, to know these warning signs for women and health care providers to rule out serious complications and initiate treatment immediately. Objectives: To determine the level of knowledge, attitude, and practice of pregnant mothers on danger signs during pregnancy among antenatal care attendants at Malka Oda general Hospital, 2019. Methods: A cross-sectional study was conducted among 208 pregnant women attending Antenatal Care from March 11-June 20/2019. A total 208 pregnant mother was selected randomly using Systematic random sampling technique. Data was collected by face to face interview. Data were processed and Analyzed. Results: This study found that 80(38.5%) were heard about obstetric danger signs while 128(61.5%) were not. One hundred ninety-two (92.3%), 15(7.2%) mothers agreed on importance of seeking medical advice on dangerous signs during pregnancy. Sixty-two (29.8%) had experienced any of danger sign during pregnancy. Of those who had experienced any of the danger signs, 59(95.2%) were sought medical care while 3 of the mothers reported that they sought care from traditional birth attendants. Conclusion: The study showed that More than two fourth of the study participants had good knowledge about danger signs during pregnancy and large number of participants had good practice. In addition, almost two over four of the studied pregnant mothers had a positive attitude towards danger sign during pregnancy.","PeriodicalId":88096,"journal":{"name":"Quality in primary care","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82916955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Care General Medicine 初级保健全科医学
Pub Date : 2021-01-01 DOI: 10.36648/1479-1072.29.1.16
Gowthami Bainaboina
Primary care means that frontline care, and it will come back from doctors (family physicians, internists, or pediatricians), medico assistants, or nurse practitioners. Medical care clinician’s area unit the quarterbacks of patient care. They create certain that their patients and their problems don’t flop the cracks of our more and more confusing health care system. Internal medicine could be a field of observe centred on treating adults. Doctors forestall, diagnose, and treat diseases that afflict all adults, from inveterately sick patients, to shortrun care. Once a doctor completes an enclosed medication residency, they're later on said as specialist. Internists generally opt to subspecialize on one malady or one a part of the body
初级保健意味着一线护理,它将来自医生(家庭医生、内科医生或儿科医生)、医疗助理或执业护士。医疗保健临床医师区单位是病人护理的四分卫。他们确保他们的病人和他们的问题不会从我们越来越混乱的医疗保健系统的裂缝中消失。内科可能是一个以治疗成人为中心的观察领域。医生预防、诊断和治疗折磨所有成年人的疾病,从久病不愈的病人到短期护理。一旦医生完成了封闭的药物住院治疗,他们后来就被称为专家。内科医生通常选择专攻一种疾病或身体的某一部分
{"title":"Primary Care General Medicine","authors":"Gowthami Bainaboina","doi":"10.36648/1479-1072.29.1.16","DOIUrl":"https://doi.org/10.36648/1479-1072.29.1.16","url":null,"abstract":"Primary care means that frontline care, and it will come back from doctors (family physicians, internists, or pediatricians), medico assistants, or nurse practitioners. Medical care clinician’s area unit the quarterbacks of patient care. They create certain that their patients and their problems don’t flop the cracks of our more and more confusing health care system. Internal medicine could be a field of observe centred on treating adults. Doctors forestall, diagnose, and treat diseases that afflict all adults, from inveterately sick patients, to shortrun care. Once a doctor completes an enclosed medication residency, they're later on said as specialist. Internists generally opt to subspecialize on one malady or one a part of the body","PeriodicalId":88096,"journal":{"name":"Quality in primary care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83737848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Influencing Trainees Career Choice among Technical and Vocational Training Trainees: Implications for Psycho-Educational Intervention 技职培训学员职业选择的影响因素:心理教育干预的启示
Pub Date : 2021-01-01 DOI: 10.36648/1479-1072.21.29.60-64
Wossen Ayalew Tegegne
Purpose: The major purpose of this study was to examine factors influencing trainees’ career choice among technical and vocational training trainees. Materials and Methods: This study was delimited to see factors influencing trainees’ career choice like family influence, peer influence, job opportunity influence and school influence on trainees’ career choice in the study area. This study was conducted in Kidus Lalibela and Kobo technical and vocational colleges. A total of 140 (78 male and 62 female) trainees was taken as samples of the study. The Stratified random sampling technique was applied to select these samples. The data gathering instruments used in the study were questionnaire. Cronbach alpha was employed to test the reliability of the instrument. The data were analyzed by using mean, variance; standard deviation and one sample t-test to describe the characteristics of the sample. Result: The findings of this study revealed that: there was a statistically significant mean difference between peer influence, school influence, job opportunity influence and the expected mean value, but there was no statistically significant mean difference between trainee’s family influence on career choice and expected mean value. Conclusion: Family, school, ministry of labor and social affairs and ministry of education should work jointly in providing accurate, timely, and relevant career related information for students at different levels.
摘要目的:本研究的主要目的是探讨职业技术培训学员职业选择的影响因素。材料与方法:本研究通过对研究区域内影响学员职业选择的家庭影响、同伴影响、工作机会影响、学校影响等因素的划分,考察影响学员职业选择的因素。这项研究是在基多斯·拉利贝拉和科博职业技术学院进行的。共选取140名学员(男78名,女62名)作为研究样本。采用分层随机抽样技术对样本进行选择。本研究的数据收集工具为问卷调查。采用Cronbach alpha检验仪器的可靠性。数据分析采用均值、方差;标准偏差和单样本t检验来描述样本的特征。结果:本研究结果显示:同伴影响、学校影响、工作机会影响与期望均值的均值差异有统计学意义,而家庭影响与期望均值的均值差异无统计学意义。结论:家庭、学校、劳动和社会事务部、教育部应共同努力,为不同层次的学生提供准确、及时、相关的职业相关信息。
{"title":"Factors Influencing Trainees Career Choice among Technical and Vocational Training Trainees: Implications for Psycho-Educational Intervention","authors":"Wossen Ayalew Tegegne","doi":"10.36648/1479-1072.21.29.60-64","DOIUrl":"https://doi.org/10.36648/1479-1072.21.29.60-64","url":null,"abstract":"Purpose: The major purpose of this study was to examine factors influencing trainees’ career choice among technical and vocational training trainees. Materials and Methods: This study was delimited to see factors influencing trainees’ career choice like family influence, peer influence, job opportunity influence and school influence on trainees’ career choice in the study area. This study was conducted in Kidus Lalibela and Kobo technical and vocational colleges. A total of 140 (78 male and 62 female) trainees was taken as samples of the study. The Stratified random sampling technique was applied to select these samples. The data gathering instruments used in the study were questionnaire. Cronbach alpha was employed to test the reliability of the instrument. The data were analyzed by using mean, variance; standard deviation and one sample t-test to describe the characteristics of the sample. Result: The findings of this study revealed that: there was a statistically significant mean difference between peer influence, school influence, job opportunity influence and the expected mean value, but there was no statistically significant mean difference between trainee’s family influence on career choice and expected mean value. Conclusion: Family, school, ministry of labor and social affairs and ministry of education should work jointly in providing accurate, timely, and relevant career related information for students at different levels.","PeriodicalId":88096,"journal":{"name":"Quality in primary care","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90240046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact 0f Pandemic Ebola Virus 0n Global Public Health 大流行埃博拉病毒对全球公共卫生的影响
Pub Date : 2021-01-01 DOI: 10.36648/1479-1072.29.4.50
Gowthami Bainaboina
{"title":"The Impact 0f Pandemic Ebola Virus 0n Global Public Health","authors":"Gowthami Bainaboina","doi":"10.36648/1479-1072.29.4.50","DOIUrl":"https://doi.org/10.36648/1479-1072.29.4.50","url":null,"abstract":"","PeriodicalId":88096,"journal":{"name":"Quality in primary care","volume":"108 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72929324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Major Factors of Elders Begging in Bahir Dar City Administration Ethiopia 埃塞俄比亚巴希尔达尔市政府老年人乞讨的主要因素
Pub Date : 2021-01-01 DOI: 10.36648/1479-1072.21.29.52-59
Mequanint Kassa Getahun
This study was conducted to explore major factors of elders who engaged in begging life. The study applied a qualitative research method. The participants were 11 elder beggars selected using accidental sampling technique and head of Bahir Dar City Administration Labour and Social affairs Department using purposive sampling technique. The main data gathering instruments used for this study were interview, observation and document review. In-depth interviews were used to collect data from participants. The study revealed that the major factors of elders to engage in begging were death of support providers, disengagement from work places, economic, family, environmental, and physical and health problems. Finally, the study recommended that the local government must include the help of NGOs, Social psychologists and also the civic bodies, so that the growth of beggary can be eliminated.
本研究旨在探讨老年人从事乞讨生活的主要因素。本研究采用定性研究方法。参与者是11名老年乞丐,采用偶然抽样技术和有目的抽样技术选择了巴希尔达尔市行政劳动和社会事务部的负责人。本研究的主要资料收集方法为访谈法、观察法和文献法。采用深度访谈的方式收集参与者的数据。研究表明,老年人从事乞讨的主要因素是赡养者死亡、脱离工作场所、经济、家庭、环境以及身体和健康问题。最后,该研究建议,地方政府必须包括非政府组织、社会心理学家和民间团体的帮助,这样才能消除乞讨者的增长。
{"title":"Major Factors of Elders Begging in Bahir Dar City Administration Ethiopia","authors":"Mequanint Kassa Getahun","doi":"10.36648/1479-1072.21.29.52-59","DOIUrl":"https://doi.org/10.36648/1479-1072.21.29.52-59","url":null,"abstract":"This study was conducted to explore major factors of elders who engaged in begging life. The study applied a qualitative research method. The participants were 11 elder beggars selected using accidental sampling technique and head of Bahir Dar City Administration Labour and Social affairs Department using purposive sampling technique. The main data gathering instruments used for this study were interview, observation and document review. In-depth interviews were used to collect data from participants. The study revealed that the major factors of elders to engage in begging were death of support providers, disengagement from work places, economic, family, environmental, and physical and health problems. Finally, the study recommended that the local government must include the help of NGOs, Social psychologists and also the civic bodies, so that the growth of beggary can be eliminated.","PeriodicalId":88096,"journal":{"name":"Quality in primary care","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82352991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Integrating the Physical Examination of The Respiratory System With Hand-Held Devices 将呼吸系统体检与手持设备相结合
Pub Date : 2021-01-01 DOI: 10.36648/1479-1072.29.3.36-40
J. Benbassat, D. Gilon, Z. Fridlender
Educators have repeatedly commented on the poor physical examination (PE) skills that students display during clerkship rotations, and since the 1970s, there have been calls to replace the traditional head-to-toe examination by other teaching approaches. The need to update the teaching of the PE is further indicated by the availability of hand-held devices. In this monograph we propose an approach to teaching the respiratory PE that consists of (a) teaching by purpose of the PE and by its clinical context (b) restricting the number of PE maneuvers by discerning between "essential", "important" and "optional" PE signs, and (c) combining the instruction of the PE with the use of hand-held devices.
教育工作者一再批评学生在实习轮转期间表现出的糟糕的身体检查(PE)技能,自20世纪70年代以来,一直有人呼吁用其他教学方法取代传统的从头到脚的检查。手持设备的出现进一步表明了更新体育教学的必要性。在这篇专著中,我们提出了一种呼吸性体育教学方法,包括(a)根据体育目的及其临床背景进行教学;(b)通过区分“必要”、“重要”和“可选”的体育标志来限制体育动作的数量;(c)将体育教学与手持设备的使用结合起来。
{"title":"Integrating the Physical Examination of The Respiratory System With Hand-Held Devices","authors":"J. Benbassat, D. Gilon, Z. Fridlender","doi":"10.36648/1479-1072.29.3.36-40","DOIUrl":"https://doi.org/10.36648/1479-1072.29.3.36-40","url":null,"abstract":"Educators have repeatedly commented on the poor physical examination (PE) skills that students display during clerkship rotations, and since the 1970s, there have been calls to replace the traditional head-to-toe examination by other teaching approaches. The need to update the teaching of the PE is further indicated by the availability of hand-held devices. In this monograph we propose an approach to teaching the respiratory PE that consists of (a) teaching by purpose of the PE and by its clinical context (b) restricting the number of PE maneuvers by discerning between \"essential\", \"important\" and \"optional\" PE signs, and (c) combining the instruction of the PE with the use of hand-held devices.","PeriodicalId":88096,"journal":{"name":"Quality in primary care","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81497741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medicine and civilization: The role of medicine in population control and civilization building from the dawn of civilization until the present time 医学与文明:医学在人口控制和文明建设中的作用,从文明之初到现在
Pub Date : 2018-01-02 DOI: 10.33140/mcr.03.01.04
Kevin M Galalae
What I am about to say will make all doctors reconsider whether they will remain in the profession or look for a different one. It will also irrevocably change the way doctors practice medicine and how people in the general population view medicine. More importantly, it will forever alter the relationship between medicine and society. And last, it will change the profession and society in ways that we can scarcely fathom but that will greatly reduce the profession’s footprint and influence and greatly increase individual and general wellbeing.
我要说的话将使所有的医生重新考虑他们是继续从事这个职业还是另谋高就。它还将不可逆转地改变医生行医的方式,以及普通民众对医学的看法。更重要的是,它将永远改变医学与社会之间的关系。最后,它将以我们几乎无法理解的方式改变职业和社会,但这将大大减少职业的足迹和影响,极大地提高个人和整体福祉。
{"title":"Medicine and civilization: The role of medicine in population control and civilization building from the dawn of civilization until the present time","authors":"Kevin M Galalae","doi":"10.33140/mcr.03.01.04","DOIUrl":"https://doi.org/10.33140/mcr.03.01.04","url":null,"abstract":"What I am about to say will make all doctors reconsider whether they will remain in the profession or look for a different one. It will also irrevocably change the way doctors practice medicine and how people in the general population view medicine. More importantly, it will forever alter the relationship between medicine and society. And last, it will change the profession and society in ways that we can scarcely fathom but that will greatly reduce the profession’s footprint and influence and greatly increase individual and general wellbeing.","PeriodicalId":88096,"journal":{"name":"Quality in primary care","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74730412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacological Study and Overcome theCardiotoxicity Associated with Anticancer DrugDoxorubicin 抗癌药物阿霉素对心脏毒性的药理研究与克服
Pub Date : 2017-01-01 DOI: 10.29011/2576-9588.100016
Muhammad Zafar, Huma Sabir
Doxorubicin, also known as Adriamycin, is an anthracycline drug commonly used in cancer chemotherapy. Adriamycin is being used clinically for solid tumours, e.g. adenocarcinoma of breast, malignant sarcomas, neuroblastoma, ovarian cancer, small lung cancer as well as hematologic malignancies including lymphomas and leukaemias. In this review we can answers different questions from which mainly we focus on that how we can prevent its toxicity and interactions with other agents and which parameters we use for to overcome this. Unfortunately, its therapeutic potential can be limited to cardiotoxicity so for to overcome this liposomal encapsulation of doxorubicin done for to overcome toxicity problems. However its use has been limited by its major clinical side effect, cardiotoxicity. Toxic effect of Adriamycin can be prevented by using different pharmacologic substances like antioxidants. Adriamycin produces its antineoplastic effect by multiple mechanisms and the exact mechanism of action of Adriamycin is still unknown. The proposed mechanism of the antineoplastic effect of Adriamycin at the cellular level is drug binding to DNA by intercalation between base pairs and inhibition of RNA synthesis by template disordering and steric obstruction.
阿霉素,又称阿霉素,是一种常用于癌症化疗的蒽环类药物。阿霉素在临床上用于治疗实体肿瘤,如乳腺腺癌、恶性肉瘤、神经母细胞瘤、卵巢癌、小肺癌以及包括淋巴瘤和白血病在内的血液恶性肿瘤。在这篇综述中,我们可以回答不同的问题,我们主要关注的是如何预防其毒性和与其他药物的相互作用以及我们使用哪些参数来克服这一点。不幸的是,它的治疗潜力可能局限于心脏毒性,因此为了克服阿霉素的脂质体包封是为了克服毒性问题。然而,由于其主要的临床副作用——心脏毒性,它的使用受到限制。阿霉素的毒性作用可以通过使用抗氧化剂等不同的药理物质来预防。阿霉素的抗肿瘤作用机制多种多样,其确切作用机制尚不清楚。在细胞水平上,阿霉素抗肿瘤作用的机制可能是药物通过插入碱基对与DNA结合,并通过模板紊乱和位阻抑制RNA合成。
{"title":"Pharmacological Study and Overcome theCardiotoxicity Associated with Anticancer DrugDoxorubicin","authors":"Muhammad Zafar, Huma Sabir","doi":"10.29011/2576-9588.100016","DOIUrl":"https://doi.org/10.29011/2576-9588.100016","url":null,"abstract":"Doxorubicin, also known as Adriamycin, is an anthracycline drug commonly used in cancer chemotherapy. Adriamycin is being used clinically for solid tumours, e.g. adenocarcinoma of breast, malignant sarcomas, neuroblastoma, ovarian cancer, small lung cancer as well as hematologic malignancies including lymphomas and leukaemias. In this review we can answers different questions from which mainly we focus on that how we can prevent its toxicity and interactions with other agents and which parameters we use for to overcome this. Unfortunately, its therapeutic potential can be limited to cardiotoxicity so for to overcome this liposomal encapsulation of doxorubicin done for to overcome toxicity problems. However its use has been limited by its major clinical side effect, cardiotoxicity. Toxic effect of Adriamycin can be prevented by using different pharmacologic substances like antioxidants. Adriamycin produces its antineoplastic effect by multiple mechanisms and the exact mechanism of action of Adriamycin is still unknown. The proposed mechanism of the antineoplastic effect of Adriamycin at the cellular level is drug binding to DNA by intercalation between base pairs and inhibition of RNA synthesis by template disordering and steric obstruction.","PeriodicalId":88096,"journal":{"name":"Quality in primary care","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75849681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Breast Cancer Chemoprevention in Primary Care- Assessing Readiness for Change 初级保健中的乳腺癌化学预防——评估改变的准备程度
Pub Date : 2016-05-20 DOI: 10.1200/JCO.2016.34.15_SUPPL.1547
Haiyun Wang, C. Snyder, Sharon Larson, V. Vogel, H. Kirchner, Haiyan Sun, Xiaowei Yan
Purpose: Despite breast cancer chemoprevention recommendations, chemoprevention use remains low. We assess primary care providers’ (PCP) awareness and use of breast cancer chemoprevention, and perceived barriers/ solutions. Methods: We conducted an online survey to investigate PCPs’ awareness and use of breast cancer chemoprevention, and perceived barriers/solutions. 161/426 (38%) eligible PCPs completed the survey. Results: Of providers, 42% reported using breast cancer risk assessment models, only 9% prescribed breast cancer chemoprevention drugs in the past year. Providers using risk models were more likely to have made a breast cancer diagnosis in the past year (77% vs. 56%; p=0.01). Providers prescribed chemoprevention were older (mean 49 years vs. 40; p=0.01), more likely to be in practice ≥ 10 years (71% vs. 43%; p=0.04) and full time (79% vs. 49%; P=0.04); they all had diagnosed breast cancer in the past year (100% vs. 61%; p=0.002). Top three reported barriers to chemoprevention guideline adherence were lack of knowledge about chemoprevention drugs, unaware of chemoprevention guidelines, and inability to identify high-risk women. After adjustment for other provider characteristics and barriers, the PCPs who are unaware of chemoprevention guidelines have 3.1 increased odds (CI: 1.4-6.7) for not using risk assessment models. If high-risk women can be identified, 85% of respondents prefer referring appropriate women to a high-risk breast clinic. Conclusion: PCPs infrequently assess breast cancer risk and rarely prescribe chemoprevention drugs for risk reduction. PCP education on breast cancer prevention and establishing high-risk breast clinics may improve breast cancer chemoprevention uptake.
目的:尽管有乳腺癌化学预防的建议,化学预防的使用仍然很低。我们评估初级保健提供者(PCP)对乳腺癌化学预防的认识和使用,以及感知到的障碍/解决方案。方法:通过在线调查,了解pcp对乳腺癌化学预防的认知和使用情况,以及感知到的障碍/解决方案。161/426(38%)合资格的pcp完成调查。结果:42%的提供者报告使用乳腺癌风险评估模型,只有9%的提供者在过去一年中开了乳腺癌化学预防药物。使用风险模型的提供者在过去一年中更有可能做出乳腺癌诊断(77%对56%;p = 0.01)。开化学预防处方的提供者年龄较大(平均49岁vs. 40岁;P =0.01),更有可能在实践≥10年(71% vs. 43%;P =0.04)和全职(79% vs. 49%;P = 0.04);他们都在过去一年中被诊断出患有乳腺癌(100%比61%;p = 0.002)。据报道,遵守化学预防指南的前三大障碍是缺乏对化学预防药物的了解,不了解化学预防指南,以及无法识别高危妇女。在对其他提供者特征和障碍进行调整后,不了解化学预防指南的pcp不使用风险评估模型的几率增加了3.1 (CI: 1.4-6.7)。如果可以确定高危妇女,85%的答复者倾向于将适当的妇女转到高危乳房诊所。结论:pcp很少评估乳腺癌风险,很少开具化学预防药物以降低风险。预防乳腺癌的PCP教育和建立高危乳腺诊所可以提高乳腺癌化学预防的接受度。
{"title":"Breast Cancer Chemoprevention in Primary Care- Assessing Readiness for Change","authors":"Haiyun Wang, C. Snyder, Sharon Larson, V. Vogel, H. Kirchner, Haiyan Sun, Xiaowei Yan","doi":"10.1200/JCO.2016.34.15_SUPPL.1547","DOIUrl":"https://doi.org/10.1200/JCO.2016.34.15_SUPPL.1547","url":null,"abstract":"Purpose: Despite breast cancer chemoprevention recommendations, chemoprevention use remains low. We assess primary care providers’ (PCP) awareness and use of breast cancer chemoprevention, and perceived barriers/ solutions. \u0000Methods: We conducted an online survey to investigate PCPs’ awareness and use of breast cancer chemoprevention, and perceived barriers/solutions. 161/426 (38%) eligible PCPs completed the survey. \u0000Results: Of providers, 42% reported using breast cancer risk assessment models, only 9% prescribed breast cancer chemoprevention drugs in the past year. Providers using risk models were more likely to have made a breast cancer diagnosis in the past year (77% vs. 56%; p=0.01). Providers prescribed chemoprevention were older (mean 49 years vs. 40; p=0.01), more likely to be in practice ≥ 10 years (71% vs. 43%; p=0.04) and full time (79% vs. 49%; P=0.04); they all had diagnosed breast cancer in the past year (100% vs. 61%; p=0.002). Top three reported barriers to chemoprevention guideline adherence were lack of knowledge about chemoprevention drugs, unaware of chemoprevention guidelines, and inability to identify high-risk women. After adjustment for other provider characteristics and barriers, the PCPs who are unaware of chemoprevention guidelines have 3.1 increased odds (CI: 1.4-6.7) for not using risk assessment models. If high-risk women can be identified, 85% of respondents prefer referring appropriate women to a high-risk breast clinic. \u0000Conclusion: PCPs infrequently assess breast cancer risk and rarely prescribe chemoprevention drugs for risk reduction. PCP education on breast cancer prevention and establishing high-risk breast clinics may improve breast cancer chemoprevention uptake.","PeriodicalId":88096,"journal":{"name":"Quality in primary care","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81898852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A Profile of the National Breast and Cervical Cancer Early Detection Program (NBCCEDP) Provider Network: Results from the Year 1 NBCCEDP Survey of Program Implementation. 国家乳腺癌和宫颈癌早期检测计划(NBCCEDP)提供者网络概况:来自第1年NBCCEDP计划实施调查的结果
Pub Date : 2015-01-01
Zachary Myles, Ketra Rice, Amy Degroff, Jackie Miller
{"title":"A Profile of the National Breast and Cervical Cancer Early Detection Program (NBCCEDP) Provider Network: Results from the Year 1 NBCCEDP Survey of Program Implementation.","authors":"Zachary Myles, Ketra Rice, Amy Degroff, Jackie Miller","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":88096,"journal":{"name":"Quality in primary care","volume":"23 6","pages":"315-317"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912227/pdf/nihms793025.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34599776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Quality in primary care
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1