Yusuke Onishi, Shigeru Kawabata, Emi Yasuda, N. Ibuki, Haruhito Azuma, Yuka Hirota, Koichi Ueda, Masashi Neo, M. Daimon, Yoshitaka Kurisu, Y. Hirose
{"title":"Bronchogenic cysts in rare sites (retroperitoneum, skin, spinal cord and pericardial cavity): A case series and characterization of epithelial phenotypes","authors":"Yusuke Onishi, Shigeru Kawabata, Emi Yasuda, N. Ibuki, Haruhito Azuma, Yuka Hirota, Koichi Ueda, Masashi Neo, M. Daimon, Yoshitaka Kurisu, Y. Hirose","doi":"10.3892/br.2023.1709","DOIUrl":"https://doi.org/10.3892/br.2023.1709","url":null,"abstract":"","PeriodicalId":8863,"journal":{"name":"Biomedical reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139005276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Dop, I. Marcu, V. Pădureanu, D. Caragea, R. Pădureanu, S. Niculescu, Carmen Niculescu
{"title":"Clostridium difficile infection in pediatric patients (Review)","authors":"D. Dop, I. Marcu, V. Pădureanu, D. Caragea, R. Pădureanu, S. Niculescu, Carmen Niculescu","doi":"10.3892/br.2023.1706","DOIUrl":"https://doi.org/10.3892/br.2023.1706","url":null,"abstract":"","PeriodicalId":8863,"journal":{"name":"Biomedical reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138589861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdulwahid Salih, L. Pshtiwan, Ari Abdullah, H. Dhahir, Halkawt Ali, Aso S. Muhialdeen, Bushra Hussein, Shko H. Hassan, Fahmi Kakamad
{"title":"Granulomatous mastitis masking ductal carcinoma in situ: A case report with literature review","authors":"Abdulwahid Salih, L. Pshtiwan, Ari Abdullah, H. Dhahir, Halkawt Ali, Aso S. Muhialdeen, Bushra Hussein, Shko H. Hassan, Fahmi Kakamad","doi":"10.3892/br.2023.1705","DOIUrl":"https://doi.org/10.3892/br.2023.1705","url":null,"abstract":"","PeriodicalId":8863,"journal":{"name":"Biomedical reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138588545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of animal venom toxins on the main links of the homeostasis of mammals (Review)","authors":"Ruzhena Matkivska, Inha Samborska, Oleksandr Maievskyi","doi":"10.3892/br.2023.1704","DOIUrl":"https://doi.org/10.3892/br.2023.1704","url":null,"abstract":"","PeriodicalId":8863,"journal":{"name":"Biomedical reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138589990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Re‑examining the mechanism of eccentric exercise‑induced skeletal muscle damage from the role of the third filament, titin (Review)","authors":"Zhao Qian, Liu Ping, Xuelin Zhang","doi":"10.3892/br.2023.1703","DOIUrl":"https://doi.org/10.3892/br.2023.1703","url":null,"abstract":"","PeriodicalId":8863,"journal":{"name":"Biomedical reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138623095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Min, Ying Zhao, Jie Du, Yongzhong Ning, Zhiqiang Wu
{"title":"Arthritis caused by Cryptococcus neoformans infection: A case report","authors":"Juan Min, Ying Zhao, Jie Du, Yongzhong Ning, Zhiqiang Wu","doi":"10.3892/br.2023.1694","DOIUrl":"https://doi.org/10.3892/br.2023.1694","url":null,"abstract":"","PeriodicalId":8863,"journal":{"name":"Biomedical reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139258426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suvinai Jiraboonsri, Panicha Hemvipat, Supitcha Kamolratanakul, Narumol Bhummaphan, T. Siritientong, N. Kitkumthorn, A. Mutirangura, Jiraroch Meevassana
{"title":"CpG methylation changes in Alu repetitive sequences in normal aging due to diastolic hypertension in human dermal fibroblasts from the facial area","authors":"Suvinai Jiraboonsri, Panicha Hemvipat, Supitcha Kamolratanakul, Narumol Bhummaphan, T. Siritientong, N. Kitkumthorn, A. Mutirangura, Jiraroch Meevassana","doi":"10.3892/br.2023.1693","DOIUrl":"https://doi.org/10.3892/br.2023.1693","url":null,"abstract":"","PeriodicalId":8863,"journal":{"name":"Biomedical reports","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139263001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ari Abdullah, Fahmi Kakamad, Aland Abdullah, Soran Tahir, Rezheen Rashid, Jihad Hama, Bnar Hama Amin, Pavel Kareem
Pulmonary osseous metaplasia is a disease in which mature bone is found within the parenchyma of the lung. The current study presents a case of pulmonary osseous metaplasia in a 64‑year‑old female. The patient was previously diagnosed with transitional cell carcinoma (TCC) of the lower ureter. During a routine check‑up, an enhancing basal lung nodule was found on chest computed tomography scan, which was suspected to be metastatic lung disease. The patient underwent a thoracoscopic resection of the nodule. The histopathological examination of the specimen confirmed it to be myeloid osseous metaplasia. The disease usually has no significant complications and can also be found in association with other pulmonary diseases. Very limited information is available on the phenomenon; therefore, there is no exact treatment guide for clinicians to follow. In conclusion, myeloid osseous metaplasia of the lung is a rare finding, and based on this report, it may be associated with TCC.
{"title":"Myeloid osseous metaplasia of the lung: A case report","authors":"Ari Abdullah, Fahmi Kakamad, Aland Abdullah, Soran Tahir, Rezheen Rashid, Jihad Hama, Bnar Hama Amin, Pavel Kareem","doi":"10.3892/br.2023.1691","DOIUrl":"https://doi.org/10.3892/br.2023.1691","url":null,"abstract":"Pulmonary osseous metaplasia is a disease in which mature bone is found within the parenchyma of the lung. The current study presents a case of pulmonary osseous metaplasia in a 64‑year‑old female. The patient was previously diagnosed with transitional cell carcinoma (TCC) of the lower ureter. During a routine check‑up, an enhancing basal lung nodule was found on chest computed tomography scan, which was suspected to be metastatic lung disease. The patient underwent a thoracoscopic resection of the nodule. The histopathological examination of the specimen confirmed it to be myeloid osseous metaplasia. The disease usually has no significant complications and can also be found in association with other pulmonary diseases. Very limited information is available on the phenomenon; therefore, there is no exact treatment guide for clinicians to follow. In conclusion, myeloid osseous metaplasia of the lung is a rare finding, and based on this report, it may be associated with TCC.","PeriodicalId":8863,"journal":{"name":"Biomedical reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134991545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Protein induced by vitamin K (VK) absence‑II (PIVKA‑II) is a sensitive marker for diagnosing hepatoma but is occasionally detected in patients without hepatoma Here, the clinical significance of serum PIVKA‑II levels in patients who were not administered warfarin and did not have hepatoma or liver disease were evaluated. As VK is related to muscle and bone metabolism, PIVKA‑II and clinical factors related to bone and muscle were compared. A total of 441 patients with various liver diseases were evaluated. Of these, 236 patients were female. Clinical factors and anthropometric measurements were obtained for each participant during outpatient visits. Among the clinical factors, type I procollagen N‑propeptide (P1NP), a low titer of undercarboxylated osteocalcin (ucOC), and 25(OH) vitamin D (VD) were used as bone metabolic markers, and SARC‑F and grip strength were used as muscle‑related markers. Serum PIVKA‑II levels above the upper limit were associated with Child B/C (Child‑Pugh score), high titers of total P1NP, and low titers of ucOC in females, and alcohol‑related liver disease and low VD in males. The titer of PIVKA‑II were associated with immunoglobulin (Ig) A and prothrombin time (PT)‑international normalized ratio (INR) in females, and fibrosis‑4‑4, IgG, total bilirubin, PT‑INR, and SARC‑F in males. Elevated PIVKA‑II levels were associated with abnormal bone physiology in females, weak muscles in males, and severe liver disease in both sexes. Assessing PIVKA‑II may assist in evaluating the clinical and bone‑muscle metabolic stages in liver disease. Nutrition and supplementation with fat‑soluble vitamins, including VK and VD may thus serve as a potential method to alleviate or prevent bone‑muscle pathophysiology in patients with liver disease.
{"title":"PIVKA‑II is associated with liver function, bone metabolism, and muscle function in patients with liver disease","authors":"Takuya Honda, Tatsuki Ichikawa, Mio Yamashima, Shinobu Yamamichi, Makiko Koike, Yusuke Nakano, Tetsurou Honda, Hiroyuki Yajima, Osamu Miyazaki, Yasutaka Kuribayashi, Tomonari Ikeda, Takuma Okamura, Kazuyoshi Nagata, Kazuhiko Nakao","doi":"10.3892/br.2023.1690","DOIUrl":"https://doi.org/10.3892/br.2023.1690","url":null,"abstract":"Protein induced by vitamin K (VK) absence‑II (PIVKA‑II) is a sensitive marker for diagnosing hepatoma but is occasionally detected in patients without hepatoma Here, the clinical significance of serum PIVKA‑II levels in patients who were not administered warfarin and did not have hepatoma or liver disease were evaluated. As VK is related to muscle and bone metabolism, PIVKA‑II and clinical factors related to bone and muscle were compared. A total of 441 patients with various liver diseases were evaluated. Of these, 236 patients were female. Clinical factors and anthropometric measurements were obtained for each participant during outpatient visits. Among the clinical factors, type I procollagen N‑propeptide (P1NP), a low titer of undercarboxylated osteocalcin (ucOC), and 25(OH) vitamin D (VD) were used as bone metabolic markers, and SARC‑F and grip strength were used as muscle‑related markers. Serum PIVKA‑II levels above the upper limit were associated with Child B/C (Child‑Pugh score), high titers of total P1NP, and low titers of ucOC in females, and alcohol‑related liver disease and low VD in males. The titer of PIVKA‑II were associated with immunoglobulin (Ig) A and prothrombin time (PT)‑international normalized ratio (INR) in females, and fibrosis‑4‑4, IgG, total bilirubin, PT‑INR, and SARC‑F in males. Elevated PIVKA‑II levels were associated with abnormal bone physiology in females, weak muscles in males, and severe liver disease in both sexes. Assessing PIVKA‑II may assist in evaluating the clinical and bone‑muscle metabolic stages in liver disease. Nutrition and supplementation with fat‑soluble vitamins, including VK and VD may thus serve as a potential method to alleviate or prevent bone‑muscle pathophysiology in patients with liver disease.","PeriodicalId":8863,"journal":{"name":"Biomedical reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136346824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}