Pub Date : 2020-01-01DOI: 10.37532/1758-1907.2020.10(4).E102
Khomassuridze
It is a great platform to share a new things on obesity and diabetes and it is organizing with the International Researchers, Doctors, Scientists, Endocrinologists, Diabetologists, Health care professionals, Delegates and Students across the globe will assemble on the venue and justify the phenomenon, the theme “Advanced approaches for Obesity and Endocrinology.Overweight and obesity has proceeded as one of the most regular global issues as it is affecting more than a billion adults worldwide. Both general and abdominal obesity have been shown as risk factors contributing for morbidity and mortality. Major global organizations have focused today on speedy treatment and prevention strategies for this epidemic which has been recognized to pose drastic threat to public health. Obesity results in reduced quality of life. This global health issue is becoming more prevalent among women and in lower social classes or immigrants; while over weight is increasing especially among children.
{"title":"Advanced approaches for Obesity and Endocrinology","authors":"Khomassuridze","doi":"10.37532/1758-1907.2020.10(4).E102","DOIUrl":"https://doi.org/10.37532/1758-1907.2020.10(4).E102","url":null,"abstract":"It is a great platform to share a new things on obesity and diabetes and it is organizing with the International Researchers, Doctors, Scientists, Endocrinologists, Diabetologists, Health care professionals, Delegates and Students across the globe will assemble on the venue and justify the phenomenon, the theme “Advanced approaches for Obesity and Endocrinology.Overweight and obesity has proceeded as one of the most regular global issues as it is affecting more than a billion adults worldwide. Both general and abdominal obesity have been shown as risk factors contributing for morbidity and mortality. Major global organizations have focused today on speedy treatment and prevention strategies for this epidemic which has been recognized to pose drastic threat to public health. Obesity results in reduced quality of life. This global health issue is becoming more prevalent among women and in lower social classes or immigrants; while over weight is increasing especially among children.","PeriodicalId":89355,"journal":{"name":"Diabetes management (London, England)","volume":"19 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69923190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.37532/1758-1907.2020.10(2).137-146
K. El-Said, Amany Abdel hamid Ezz, Amira Mohamed
Background: Diabetes Mellitus is a metabolic defect that has the ability to produce an irreversible injury, abnormality of function and defect of several organs. Stem cell treatment posses a fantastic hope for the remedy damaged tissues or organs, and it is one of the utmost hopeful remedy for diabetic people. Thus, the current research direct to highlights of the potency function of MSCs of diabetic female rats. Methodology: Male albino bone marrow mesenchymal stem cells have been isolated and confirmed by their adhesion, spindle shape and also by cluster differentiation marker. Streptozotocin-induced diabetic female rats were intravenous injected by 1 x 105 MSCs (cell/rat). Results: MSCs group is capable of lowering blood glucose level, the activities of α-amylase, and S. L-MDA. However, hepatic glycogen contents showed an incredible increase when compared with the STZ-diabetic female nontreated rats. The histopathological and immuno-histochemical photo results confirmed that MSCs group noteworthy diminutive the degenerative alteration in pancreatic β-cells islet. Conclusions: Using bone marrow MSCs in remedy of STZ-diabetic female rats have the ability to recover odd biochemical parameters to normal or near normal level in STZ-induced diabetes model. But, MSCs needs more research and it may be more effective by injection more than one dose.
{"title":"The potential role of male bone marrow mesenchymal stem cells of diabetic female rats","authors":"K. El-Said, Amany Abdel hamid Ezz, Amira Mohamed","doi":"10.37532/1758-1907.2020.10(2).137-146","DOIUrl":"https://doi.org/10.37532/1758-1907.2020.10(2).137-146","url":null,"abstract":"Background: Diabetes Mellitus is a metabolic defect that has the ability to produce an irreversible injury, abnormality of function and defect of several organs. Stem cell treatment posses a fantastic hope for the remedy damaged tissues or organs, and it is one of the utmost hopeful remedy for diabetic people. Thus, the current research direct to highlights of the potency function of MSCs of diabetic female rats. Methodology: Male albino bone marrow mesenchymal stem cells have been isolated and confirmed by their adhesion, spindle shape and also by cluster differentiation marker. Streptozotocin-induced diabetic female rats were intravenous injected by 1 x 105 MSCs (cell/rat). Results: MSCs group is capable of lowering blood glucose level, the activities of α-amylase, and S. L-MDA. However, hepatic glycogen contents showed an incredible increase when compared with the STZ-diabetic female nontreated rats. The histopathological and immuno-histochemical photo results confirmed that MSCs group noteworthy diminutive the degenerative alteration in pancreatic β-cells islet. Conclusions: Using bone marrow MSCs in remedy of STZ-diabetic female rats have the ability to recover odd biochemical parameters to normal or near normal level in STZ-induced diabetes model. But, MSCs needs more research and it may be more effective by injection more than one dose.","PeriodicalId":89355,"journal":{"name":"Diabetes management (London, England)","volume":"10 1","pages":"10-20"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69923088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.37532/1758-1907.2020.10(4).E105
L. Kao
Diabetes Management presents findings, analysis and commentary on the battle with Type I and Type II diabetes. Articles published in Diabetes Management address improvements in current therapeutics and patient compliance together with perspectives on future prospects. Coverage focuses on the key objective of stabilizing blood glucose levels in individuals with either form of the disease, and the associated issues of patient co-operation and education. The journal also reflects the frontiers of current research, such as attempts to recreate pancreatic cells through stem cell technology or islet cell transplantation, the development of a vaccine for Type 1 disease and the potential for biomarkers to be used for the detection. The increasing understanding of the molecular basis of the disease and associated genetics will play an important part in future diabetes management.
{"title":"Glimpses of Diabetes Management","authors":"L. Kao","doi":"10.37532/1758-1907.2020.10(4).E105","DOIUrl":"https://doi.org/10.37532/1758-1907.2020.10(4).E105","url":null,"abstract":"Diabetes Management presents findings, analysis and commentary on the battle with Type I and Type II diabetes. Articles published in Diabetes Management address improvements in current therapeutics and patient compliance together with perspectives on future prospects. Coverage focuses on the key objective of stabilizing blood glucose levels in individuals with either form of the disease, and the associated issues of patient co-operation and education. The journal also reflects the frontiers of current research, such as attempts to recreate pancreatic cells through stem cell technology or islet cell transplantation, the development of a vaccine for Type 1 disease and the potential for biomarkers to be used for the detection. The increasing understanding of the molecular basis of the disease and associated genetics will play an important part in future diabetes management.","PeriodicalId":89355,"journal":{"name":"Diabetes management (London, England)","volume":"10 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69923011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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